Treatment FAQ

treatment of stroke may include which of the following medications?

by Dr. Trevor Murazik DDS Published 2 years ago Updated 2 years ago
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Medication

After a stroke, your doctor may prescribe oral drugs, such as clopidogrel (Plavix) or warfarin (Coumadin). These are used to thin your blood in order to reduce the risk of stroke in the future.

Procedures

Emergency treatment for stroke depends on whether you're having an ischemic stroke or a stroke that involves bleeding into the brain (hemorrhagic). To treat an ischemic stroke, doctors must quickly restore blood flow to your brain. This may be done with: Emergency IV medication.

Therapy

It aims to break up the blood clot that’s blocking or disrupting blood flow in the brain. Doctors often use aspirin in the treatment of strokes. Aspirin thins your blood and can even help prevent future strokes. As a preventive medication, it's especially effective in preventing secondary stroke.

Nutrition

Pharmacotherapeutic options for primary ischemic stroke are tissue plasminogen activator (tPA) and—under defined conditions—antiplatelet agents. Pharmacotherapeutic treatment for hemorrhagic stroke is aimed at controlling the patient’s blood pressure and intracranial pressure.

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What medications are used to treat stroke patients?

How is a stroke treated in the emergency room?

How does aspirin treat a stroke?

What are the pharmacotherapeutic options for primary ischemic stroke?

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What are the preventive measures for stroke?

Post-stroke preventive measures mainly focus on improving cardiovascular health. This might mean lowering your blood pressure and managing your blood sugar and cholesterol, or lipid, levels.

Why are statins used in stroke prevention?

These are used to thin your blood in order to reduce the risk of stroke in the future. Statins have also been shown to reduce the incidence of future stroke.

Why does hemorrhagic stroke cause swelling?

Hemorrhagic stroke occurs when a brain aneurysm bursts or a weakened blood vessel leaks. This causes blood to leak into your brain, creating swelling and pressure. Unlike ischemic strokes, treatment for hemorrhagic strokes doesn’t involve blood thinners. This is because thinning your blood would cause the bleeding in your brain to become worse.

How long does it take for a stroke to start?

They occur when a blood clot blocks blood flow to your brain. Medication treatment for this type of stroke must start within 4.5 hours of the event, according to 2018 guidelines from the American Heart Association (AHA) and the American Stroke Association (ASA).

How does a stroke affect you?

How a stroke affects you depends on the location in your brain where the stroke occurs. Evaluation and treatment for a stroke should begin as soon as possible. The quicker emergency treatment begins, the greater the chance of preventing lasting damage. Treatment depends on the type of stroke you’re having.

What is the best medication to break up a clot?

Your doctor may also administer drugs to break up clots. A common intravenous (IV) drug is tissue plasminogen activator (tPA). It’s given during an active stroke if the person is a good candidate. This medication works to stop a stroke by dissolving the clot that’s causing it.

Why does blood thinner cause brain bleeds?

This is because thinning your blood would cause the bleeding in your brain to become worse. If you’re already taking blood-thinning medications, your doctor may administer drugs to counteract them or to lower your blood pressure to slow the bleeding in your brain.

What is the best medicine for a stroke?

If you get to the hospital within 3 hours of the first symptoms of an ischemic stroke, you may get a type of medicine called a thrombolytic (a “clot-busting” drug) to break up blood clots. Tissue plasminogen activator (tPA) is a thrombolytic. tPA improves the chances of recovering from a stroke.

Why is it important to treat strokes?

Your doctor may give you medications or tell you to change your diet, exercise, or adopt other healthy lifestyle habits.

How to treat hemorrhagic stroke?

Surgical treatment. Hemorrhagic strokes may be treated with surgery. If the bleeding is caused by a ruptured aneurysm, a metal clip may be put in place to stop the blood loss.

What do you ask at a stroke hospital?

At the hospital, health professionals will ask about your medical history and about the time your symptoms started. Brain scans will show what type of stroke you had. You may also work with a neurologist who treats brain disorders, a neurosurgeon that performs surgery on the brain, or a specialist in another area of medicine.

What is the best way to get to the hospital for a stroke?

Stroke Treatment. Calling 9-1-1 at the first symptom of stroke can help you get to the hospital in time for lifesaving stroke care. Your stroke treatment begins the moment emergency medical services (EMS) arrives to take you to the hospital. Once at the hospital, you may receive emergency care, treatment to prevent another stroke, ...

Why do people go to the hospital for stroke?

Stroke patients who are taken to the hospital in an ambulance may get diagnosed and treated more quickly than people who do not arrive in an ambulance. 1 This is because emergency treatment starts on the way to the hospital. The emergency workers may take you to a specialized stroke center to ensure that you receive the quickest possible diagnosis ...

What is needed to stop brain bleed?

Medicine, surgery, or other procedures may be needed to stop the bleeding and save brain tissue. For example:

What is the first goal of the evaluation of a suspected ischemic stroke?

The first goal of the evaluation of a suspected ischemic stroke is to exclude intracranial hemorrhage with neuro-imaging.

What medications are used for maintenance therapy?

Note: Other oral antihypertensive medications (e.g., diuretics, captopril,clonidine, metoprolol, and hydralazine) may be utilized for maintenance therapy if the patient has passed a dysphagia screening

What is the maximum blood pressure for thrombolytic therapy?

Thrombolytic therapy is not given to patients who have a systolic blood pressure above 185 mmHg or a diastolic blood pressure above 110 mmHg despite non-aggressive blood pressure-lowering attempts. While there is no established definition of “non-aggressive” blood pressure reduction, a common approach is to use a maximum of two to three attempts with parenteral medications, with options including labetalol, enalaprilat or nicardipine. Uncontrolled blood pressure is an uncommon reason for ineligibility of IV alteplase for AIS. [6]

What is the treatment for AIS?

Drug treatment of AIS involves intravenous thrombolysis with alteplase (recombinant tissue plasminogen activator [rtPA]). Intravenous alteplase promotes thrombolysis by hydrolyzing plasminogen to form the proteolytic enzyme plasmin. Plasmin targets the blood clot with limited systemic thrombolytic effects. Alteplase must be administered within a short time window to appropriate patients to optimize its therapeutic efficacy. Recent trials have shown this time window may be extended from 3 to 4.5 hours in select patients. Other acute supportive interventions for AIS include maintaining normoglycemia, euthermia and treating severe hypertension. Urgent anticoagulation for AIS has generally not shown benefits that exceed the hemorrhage risks in the acute setting. Urgent antiplatelet use for AIS has limited benefits and should only promptly be initiated if alteplase was not administered, or after 24 hours if alteplase was administered. The majority of AIS patients do not receive thrombolytic therapy due to late arrival to emergency departments and currently there is a paucity of acute interventions for them. Ongoing clinical trials may lead to further medical breakthroughs to limit the damage inflicted by this devastating disease.

Why is body temperature important in stroke?

Increased body temperature in the setting of acute ischemic stroke has been associated with poor neurologic outcome, possibly due to increased metabolic demands, enhanced release of neurotransmitters, and increased free radical production. Maintaining normothermia might improve the prognosis of patients with severe events using antipyretic medications and cooling devices. [10,11]Hypothermia has been shown to be neuroprotective after experimental animal models of global and focal hypoxic brain injury, and it is currently under clinical study for acute ischemic stroke. [10,11]Antipyretic therapy is indicated for temperatures above 37.5 °C.

What is the blood pressure of a patient who is not aggressive?

Blood pressure not elevated (systolic <185 mmHg and diastolic <110 mmHg)after non-aggressive treatment

Does alteplase help with stroke?

Intravenous thrombolysis with alteplase is the mainstay medical treatment for acute ischemic stroke (AIS). While antiplatelet therapy with aspirin (acetylsalicylic acid) has been shown to decrease the risk of early recurrent stroke when initiated within 48 hours of ischemic stroke onset, it does not actually treat the stroke that has already occurred. Newer antiplatelet agents, alone and in combination with aspirin, have shown promising results for further prevention of early recurrence, and clinical trials are ongoing. Acute therapeutic anticoagulation with unfractionated heparin (UFH) and low molecular weight heparin (LMWH) administered to unselected patients have not demonstrated clinical benefits in the acute ischemic stroke setting over antiplatelet agents. More studies are needed to demonstrate the role of acute anticoagulation in specific circumstances in which the risk of early stroke recurrence is high. [12]

What blood pressure should be administered to a patient with a high systolic blood pressure?

D. You should administer nitroglycerin or labetalol if her systolic blood pressure is greater than 150 mm Hg.

Can fibrinolytic therapy be given in the emergency department?

B. The patient will likely receive fibrinolytic therapy in the emergency department if no contraindications exist.

Is a postictal phase present?

D. a postictal phase is not present.

What causes 50% of strokes?

A) They account for 50% of all strokes and are caused by an occlusion of a vein to a region of the brain.

What is the only treatment for an unstable tachycardic individual?

Medication is the only treatment for an unstable tachycardic individual.

Why should you defibrillate if you have no pulse?

If the AED advises no shock, you should still defibrillate because defibrillation often restarts the heart with no pulse.

Why is defibrillation important?

Urgent defibrillation is essential for survival in the management of acute strokes.

What causes strokes in the brain?

B) They account for 87% of all strokes and are usually caused by an occlusion of an artery to a region of the brain.

When should an individual be cleared before a shock?

An individual should be cleared-Ñ prior to a shock only when convenient.

Is 100% oxygen safe for early intervention?

100% oxygen is acceptable for early intervention but not for extended periods of time.

What is the pharmacologic treatment for a stroke?

9 The pharmacologic treatment of a stroke depends upon whether the stroke is ischemic or hemorrhagic. Pharmacotherapeutic options for primary ischemic stroke are tissue plasminogen activator (tPA) and—under defined conditions—antiplatelet agents. Pharmacotherapeutic treatment for hemorrhagic stroke is aimed at controlling the patient’s blood pressure and intracranial pressure.

How to treat a hemorrhagic stroke?

Treatment of any patient who has experienced a hemorrhagic stroke includes the following steps: determining the cause of bleeding; controlling the patient’s blood pressure; stopping any medications that may heighten the risk of further bleeding; and controlling the patient’s intracranial pressure. 16.

What causes a stroke to decrease blood flow?

The reduction in blood flow that occurs during a stroke is due primarily to either ischemia or hemorrhage. Of the two major types of stroke (ischemic and hemorrhagic), the ischemic form is more common, accounting for 85% to 87% of stroke cases. 3 Ischemic stroke occurs when an artery supplying the brain is occluded, leading to decreased blood flow to the affected area. A variety of diseases can cause occlusion, most commonly large-artery disease, small-vessel disease, and cardioembolism. 4 The causes of an ischemic stroke may be more generally categorized as embolism and thrombosis, with thrombosis occurring more frequently. Thrombotic stroke occurs when a clot forms in a vessel and reduces blood flow to the brain from the location where the clot originates. In embolic stroke, the clot forms in an area apart from the brain, loosens, and travels until it reaches a blood vessel that is too narrow to allow it to pass. This occlusion impedes the flow of blood to the brain.

What happens when a blood vessel in the brain becomes weak and ruptures?

Hemorrhagic stroke occurs when a blood vessel in the brain becomes weak and ruptures. The blood then leaks into other parts of the brain, damaging the surrounding tissue. Hemorrhagic stroke may be classified in one of two ways, depending upon the location of the bleed. Subarachnoid hemorrhage results from a ruptured blood vessel between ...

How long does it take for aspirin to work?

Aspirin therapy (325 mg) should begin within 24 to 48 hours of an ischemic stroke, but not within 24 hours of completion of alteplase therapy. 12 Alternatively, it is recommended that patients who are ineligible for treatment with a thrombolytic agent receive early aspirin therapy (starting dose 150-325 mg).

What causes occlusion in a stroke?

4 The causes of an ischemic stroke may be more generally categorized as embolism and thrombosis , with thrombosis occurring more frequently.

How many neurons are lost in a stroke?

For each minute that a patient with a large-vessel ischemic stroke goes untreated, an average of 1.9 million neurons are lost. 6 Stroke is a time-sensitive condition, making it important for patients, caregivers, and health professionals to recognize its signs and symptoms.

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Diagnosis

Treatment

Treatment Outcomes

Clinical Trials

Medically reviewed by
Dr. Karthikeya T M
Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Treatment is based on the type of stroke. For ischemic stroke or transient ischemic attack, medication or surgery or both can be recommended and for hemorrhagic stroke, surgery is recommended.
Medication

Clot dissolver: To dissolve clots and reopen arteries.

Plasminogen activator (tPA)


Anticoagulants: Has the effect of retarding or inhibiting the coagulation of blood.

Aspirin . Clopidogrel

Procedures

Catheter mediated intra-arterial thrombolysis: To attain reperfusion in case of ischemic stroke or transient ischemic attack.

Angioplasty and stent placement: Widens the blocked artery and a stent is placed.

Aneurysm clipping: To treat a balloon-like bulge of an artery wall known as an aneurysm.

Coil embolization: To treat aneurysm that may have caused hemorrhagic stroke.

Carotid endarterectomy: To correct stenosis (narrowing) in the common carotid artery or internal carotid artery.

AVM removal: Carried out in case of hemorrhagic stroke.

Therapy

Rehabilitation:The rehabilitation is advised to start as early as possible upon recovery. Rehabilitation program will be decided as per the necessity and usually focuses on speech therapy; cognitive therapy; sensory and motor skills; and physical therapy.

Nutrition

Foods to eat:

  • Fruits and vegetables: eat plenty of fruit and vegetables; between 5-7 servings per day
  • Whole grain breads and cereals containing fiber and vitamins: They may reduce the risk of stroke
  • Lean protein: Limiting the amount of cholesterol is another important step in reducing the risk of another stroke
  • Choose low-fat meats or other protein
  • Limit salt: Eating too much salt/sodium may cause you to retain water and raise your blood pressure

Foods to avoid:

  • Heavy cholesterol foods
  • foods rich in salt and sugar
  • Alcohol

Specialist to consult

Neurologist
Specializes in treating diseases of the nervous system, which includes the brain, the spinal cord, and the nerves.
Neuroradiologist
Specializes in the use of radioactive substances, x-rays and scanning devices for the diagnosis and treatment of diseases of the nervous system.
Occupational therapist
A healthcare professional who helps in development, recovery, or management of everyday activities, or occupations.
Speech therapist
A health professional who specializes in evaluating and treating voice, speech, language, or swallowing disorders.
Physical therapist
A health professional who helps patients reduce pain and improve or restore mobility.

Coping and Support

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Things will move quickly once you get to the hospital, as your emergency team tries to determine what type of stroke you're having. That means you'll have a CTscan or other imaging test soon after arrival. Doctors also need to rule out other possible causes of your symptoms, such as a brain tumor or a drug reaction.
See more on mayoclinic.org

Preparing For Your Appointment

  • Emergency treatment for stroke depends on whether you're having an ischemic stroke or a stroke that involves bleeding into the brain (hemorrhagic).
See more on mayoclinic.org

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