Treatment FAQ

treatment for eye musclle which atrophy's due to lack of oxygen

by Noel Hoppe Published 2 years ago Updated 2 years ago

Treatment with intramuscular B12 as well as oral B12 supplementation has been found to result in dramatic improvement in vision. 1 Compressive optic neuropathy results from a tumor or other lesion pressing on the optic nerve or from eye movement muscle enlargement which is seen in hyperthyroidism (Graves' disease) patients.

Full Answer

Is there any treatment for optic atrophy?

There are some diseases of the eye and optic nerve that can cause optic atrophy too. Treatment for optic atrophy depends on the root cause. The optic nerve has about 1.2 million axons, originating at the ganglion cell layer, which is on the retina.

What is circulatory atrophy of the eye?

Circulatory atrophy (vascular): A type of ischemic optic neuropathy that is caused when perfusion pressure of the ciliary body falls below the intraocular pressure. This often can be appreciated in conditions such as central retinal artery occlusion, carotid artery occlusion, and cranial arteritis.

What are the causes of optic atrophy?

In the case of optic atrophy, something is interfering with the optic nerve's ability to transmit these impulses. The interference can be caused by numerous factors, including: Glaucoma. Stroke of the optic nerve, known as anterior ischemic optic neuropathy.

What is muscle atrophy and how is it treated?

Muscle atrophy is the wasting or thinning of muscle mass. It can be caused by disuse of your muscles or neurogenic conditions. Symptoms include a decrease in muscle mass, one limb being smaller than the other, and numbness, weakness and tingling in your limbs. Disuse atrophy can be reversed with exercise and a healthy diet.

Is there any treatment for optic atrophy?

There is no real cure or treatment for optic atrophy. Therefore, it's important to have regular eye exams (especially if you have a family history of eye diseases), and to see your ophthalmologist immediately if you have any changes in your vision.

Can optic atrophy reversed?

Damage from optic nerve atrophy cannot be reversed. The underlying disease must be found and treated. Otherwise, vision loss will continue. Rarely, conditions that lead to optic atrophy may be treatable.

Can optic atrophy be stopped?

Unfortunately, there is no effective treatment for optic atrophy. Once the nerve fibers in the optic nerve are lost they never heal or grow back. However, early diagnosis and treatment of the underlying causes of optic atrophy can help prevent further damage from the disease.

What causes lack of oxygen to the optic nerve?

Causes of Eye Stroke Eye stroke is caused by poor circulation in the blood vessels that supply the front portion of the optic nerve. The optic nerve is the cable that connects the brain to the eye and carries millions of nerve fibers and blood vessels.

Does optic atrophy show up on MRI?

[19] The diagnosis is based on opthalmoscopic findings. MRI reveals diffuse bilateral optic nerve atrophy.

Does optic atrophy get worse?

Unfortunately, medical science has not yet developed an effective treatment for Optic Atrophy, because once nerve fibers are lost, they cannot heal and do not grow back. However early diagnosis and treatment of the underlying cause of optic atrophy can help prevent damage from getting worse.

Can you drive with optic atrophy?

The patient with optic neuritis must not drive. The resolution of the causal clinical condition will force to evaluating the patient for possible visual sequels, and with a medical report before permitting driving.

How can I strengthen my optic nerve?

There are no effective treatments to regenerate nerve cells or to restore connections between the eye and brain once the optic nerve is lost. This is a major barrier in the field and one that must be overcome, given the substantial number of patients suffering from optic neuropathy-associated blindness.

What age group is affected by optic atrophy?

Optic atrophy type 1 (OPA1, or Kjer type optic atrophy) is characterized by bilateral and symmetric optic nerve pallor associated with insidious decrease in visual acuity (usually between ages 4 and 6 years), visual field defects, and color vision defects.

How can I get more oxygen to my eyes?

Exercise regularly Growing scientific evidence suggests that aerobic exercise can increase crucial oxygen supplies to the optic nerve and lower pressure in the eye.

What happens if your eyes don't get enough oxygen?

Symptoms of oxygen deprivation in the eyes includes blurred vision, burning, excessive tearing and a scratchy feeling, almost like there is sand in the eye. Mild cases typically result in swelling in the epithelial layer of the cornea and temporary blurred vision.

What is the treatment for optic neuropathy?

Optic neuritis usually improves on its own. In some cases, steroid medications are used to reduce inflammation in the optic nerve. Possible side effects from steroid treatment include weight gain, mood changes, facial flushing, stomach upset and insomnia. Steroid treatment is usually given by vein (intravenously).

How to treat ophthalmoplegia?

Surgery can be performed in some cases to remove brainstem lesions that are causing INO. There are some situations where the condition is caused by infections, Lyme disease, or syphilis, which can be treated with antibiotics and antiviral therapies. Patients find that once the underlying condition improves, so does the ophthalmoplegia.

What is the condition where the eye muscles are weak?

Ophthalmoplegia or eye muscle weakness is a condition that is characterized by either paralysis or weakness of the eye muscles. It can lead to a lack of eye mobility and even permanent eye drooping, since it can affect one or more of the six muscles that hold the eyes in place.

What Causes Muscle Weakness in the Eye?

Ophthalmoplegia causes vary from person-to-person and can be associated with muscle disorders, thyroid issues, stroke, and other neurological problems – or, you could be born with it. Medical research suggests that it’s due to a disruption of messages that are sent from the brain to the eyes.

Why does ophthalmoplegia occur?

Medical research suggests that it’s due to a disruption of messages that are sent from the brain to the eyes. Internal ophthalmoplegia has been linked to multiple sclerosis, trauma, and infarction, while mitochondrial diseases – including Graves’ disease or Kearns-Sayre syndrome – can cause external ophthalmoplegia.

What are the symptoms of ophthalmoplegia?

Difficulty moving the eye. Eye pain and/or headaches. Ptosis, which is the drooping of the eye. Decreased peripheral vision. People who are born with ophthalmoplegia often find that it advances to the point where they experience double vision along with some of the symptoms mentioned above.

When does progressive ophthalmoplegia start?

Chronic progressive ophthalmoplegia or PEO tends to appear in adults between the ages of 18 and 40. Usually, it starts with drooping eyelids and difficulty controlling muscles that are normally used to coordinate the eyes.

Why do we need to exercise our eyes?

Your eyes have muscles like the rest of your body which means they require exercise to boost circulation and strength. Incorporating eye exercises into your daily routine may help improve muscle weakness, which may help them work more efficiently.

What is the term for the weakness of the eye muscles?

What is Ophthalmoplegia (Weak Eye Muscles)? Ophthalmoplegia refers to the weakness or paralysis of the eye muscles. The condition can affect one or more of the six muscles that keep the eye in place and control its movement. This can lead to eye movement abnormalities.

How to diagnose ophthalmoplegia?

Ophthalmoplegia is diagnosed with a physical examination to assess eye movements. Then an MRI or CT scan may be required to look at the eye close up. Blood tests may be needed to determine whether ophthalmoplegia is caused by another condition, like thyroid disease.

What Causes Ophthalmoplegia?

Ophthalmoplegia can be congenital, which means present at birth. Or it can develop later in life.

What is the term for the area of the brain that is affected by MS?

The term internuclear refers to the area of the brain affected. It is an area that works as a pathway between the nuclei. These are two clusters of nerve cells in the brain. Around 23 percent of MS patients have internuclear ophthalmoplegia. Other conditions that may result in internuclear ophthalmoplegia include:

Which muscle moves the eye up and down?

These muscles enable the eye to move up, down, side to side, and roll in a circle. This type of ophthalmol may affect any of the following six extraocular muscles: Superior rectus. A muscle fixed to the top of the eye that moves the eye upward. Inferior rectus.

Which muscle is responsible for allowing the eye to focus on objects?

This type of opthalmoplegia may affect any of the following three internal muscles of the eye: Ciliary muscle . A ring of muscle that affects the shape of the lens. This enables the eye to focus on nearby or far away objects. Dilator pupillae. A muscle that largens the size of the pupil to let in more light.

Can you have double vision in one eye?

If the right eye is affected, the individual will have double vision when looking to the left. This type of ophthalmoplegia may develop in one eye (unilateral internuclear ophthalmoplegia) or both eyes (bilateral internuclear ophthalmoplegia).

When does optic nerve atrophy occur?

Optic nerve atrophy type 1 appears in childhood, or during puberty , with visual loss that progresses during puberty until adulthood. The subsequent progression is chronic and very slow. This is a complete and permanent breakdown of optic nerve fibers.

What is the term for the damage to the optic nerve?

Optic nerve atrophy , also known as optic neuropathy, simply defined, is the end result of any disease that damages nerve cells anywhere between the retina and a part of the thalamus that links the eye to the brain. Optic nerve atrophy is the condition wherein the optic nerve is limited in its capacity to transmit information accurately.

What does it mean when an ophthalmologist looks at your eye?

When the ophthalmologist looks in your eye she can see that the pale optic nerve is visibly atrophied and looks pale. It has partially or seriously wasted away resulting in partial or serious loss or change in vision.

What causes optic nerve damage?

Toxic optic neuropathy. Optic atrophy can result from nutritional deficiencies, some medications, and toxins which damage the optic nerve causing gradual or sudden vision loss. The most common optic neuropathy from poisons and toxins is called as tobacco-alcohol amblyopia, thought to be caused by exposure to cyanide from tobacco smoking, and by low vitamin B12. Other toxins include methyl alcohol (moonshine), ethylene glycol (antifreeze), cyanide, lead, and carbon monoxide.

What happens to the optic nerve when it is lost?

In optic nerve atrophy nerve fibers atrophy and are lost, the protective myelin sheath around them shrinks, gliosis occurs and the optic cup (where the optic nerve enters the retina) widens. Gliosis means that glia cells proliferate or enlarge, crowding the nerve cells.

Can optic nerve atrophy be caused by a faulty optic nerve?

Most commonly, optic nerve atrophy occurs without a known or proven cause.

Is optic neuropathy genetic?

It is closely associated to a group of conditions, some of which are genetically based , while others are due to lifestyle considerations, such as chronic systemic inflammation, trauma, toxins, poor blood flow, and/or a lack of essential nutrients getting to the optic nerve. Thus, the prevalence of optic nerve atrophy depends on the prevalence of an underlying cause.

Why is it important to protect the other eye during treatments involving optic atrophy?

It is also important to protect the other eye during treatments involving optic atrophy. While many conditions do not damage the eyes symmetrically , chronic health problems can begin to damage the other eye after the first optic nerve begin s to atrophy.

What Is Optic Atrophy?

Optic atrophy, or optic nerve atrophy, is damage to the optic nerve that causes the tissues to degrade and die. This leads to a loss of vision. Light that moves through the eye hits the retina and is not processed in the brain since the signals are not transmitted by the optic nerve.

What is secondary optic atrophy?

Secondary optic atrophy, in which optic nerve fibers degenerate with excessive proliferation and invasion of glial tissue, which dramatically changes how the area around the retina looks on eye exams.

What causes optic nerve atrophy?

Atrophy of the optic nerve most often occurs in older adults, usually 60 or older. Toxins in the environment, radiation, trauma, and shock can also cause optic atrophy by harming surrounding tissues or cutting off blood flow. Blindness attributed to optic atrophy occurs in about 0.8 percent of the population.

What is the optic nerve?

The optic nerve is a vital part of seeing the world around you. There are several conditions that can lead to damage to this area, including tumors, glaucoma, loss of blood flow, toxins, injury, and heredity. ( Learn More) Types of atrophy of the optic nerve depend on where the problem starts. ( Learn More)

How many axons does the optic nerve have?

The optic nerve has about 1.2 million axons, originating at the ganglion cell layer, which is on the retina. These cells are myelinated, and once they are damaged in any way, they do not regenerate. Vision loss stemming from this area is typically irreversible. There are four parts to the optic nerve:

How do you know if you have optic atrophy?

The most common and noticeable symptom of optic atrophy is dimming vision along with reduced field of vision. This could be sudden, with the experience passing, or it could be gradual and hard to fully notice. You may experience a dimming in your vision, which passes; you may slowly lose peripheral vision, or central vision; you may lose color vision; or you may lose spots of vision.

How to diagnose optic atrophy?

If your ophthalmologist suspects you may be suffering from optic atrophy, the first thing they will do is get a direct close up look at the eye with a tool called an ophthalmoscope. This tool will allow your doctor to look at the optic disc (the point where the optic nerve enters). Depending on the color of this disc, change in blood flow to the eye can be suspected. A pale optic disc would indicate decreased blood flow, for example.

What are the causes and symptoms of optic atrophy?

The term “optic atrophy” implies the wasting away of optic nerve cells due to underuse or neglect, which is not a completely accurate description of the condition, as damage to the optic nerve is a causative factor. Any disease that can compromise ganglion cell function (a type of neuron found near the inner surface of the retina) can lead to the development of optic atrophy over time.

Why is the optic nerve inflamed?

Because the optic nerve is an important player in visual signaling to the brain, inflammation of it is often impaired. Inflammation of the optic nerve can be seen in conditions such as multiple sclerosis, diabetes mellitus, low phosphorus levels, or hyperkalemia.

What is the ascending type of atrophy?

Consecutive atrophy: An ascending type of atrophy that includes the likes of chorioretinitis, pigmentary retinal dystrophy, and cerebromacular degeneration. Circulatory atrophy (vascular): A type of ischemic optic neuropathy that is caused when perfusion pressure of the ciliary body falls below the intraocular pressure.

What causes optic nerve atrophy?

However, optic atrophy may also be caused by shock, radiation, toxic substances, or trauma. Disease of the brain or central nervous system, stroke, brain tumor, as well as eye diseases such as glaucoma may also lead to the condition.

What is optic atrophy?

Optic atrophy (optic neuropathy) is a term used to refer to the end stage of a number of conditions that can cause optic nerve damage. The optic nerve is composed of a bundle of nerve fibers, each of which transports visual information from the retina to the visual processing centers of the brain. Significant damage or degeneration ...

What causes a person to lose vision?

Other causes: Giant cell arteritis (arthritic ischemic optic neuropathy) Chronic papilledema. Chronic optic neuritis.

What is the best way to check for optic atrophy?

Ophthalmologists usually conduct a detailed eye exam If they suspect that you could have optic atrophy. An instrument, an ophthalmoscope, is used to examine the optic disc, which is the point at which the optic nerve connects at the back of the eye. In people with optic nerve damage, this disc appears unusually pale in color.

What is optic nerve atrophy?

Optic atrophy is a visual complication that may occur as a result of certain eye diseases. Let’s take a brief look at the most common causes of optic nerve atrophy:

What does it mean when your eye is pale?

Also, a dilated eye examination with an ophthalmoscope shows that the eye with optic nerve atrophy appears pale, instead of the typically pinkish hue of the optic nerve.

What is the name of the condition where the optic nerve is underdeveloped?

Optic nerve hypoplasia (ONH) is a congenital disease in which the optic nerve is considerably underdeveloped and has much fewer nerve fibers out of the 1.2 million average nerve fibers in the optic nerve of a healthy person. Most of the time, children with ONH have diminished vision in both eyes.

What is the main cause of blindness?

In a research study published by National Institute of Health, Optic Atrophy was identified as one of the five main causes of blindness. Given the amount of visual damage that can be caused by optic nerve atrophy, we must look into its causes and ways to prevent the damage.

Why is IrisVision used?

Devices such as IrisVision are built to facilitate its users so they can attain the same level of visual acuity, color vision and quality as an average person. The headset covers for the visual difficulties caused by Nerve Atrophy, such as blurred vision, reduced vision, reduced peripheral vision etc.

Which part of the eye is responsible for the formation of vision?

The optic nerve extends at the back of each eye, which connects the retina to the brain. It holds a very vital role in the vision formation process. The visual stimuli we receive from the external environment travel towards the optic nerve, which transmits them to the brain. These stimuli are processed in the occipital lobe of the brain and are converted into images that we can understand, see and experience.

What does it feel like to have oxygen in your eyes?

Symptoms of oxygen deprivation in the eyes includes blurred vision, burning, excessive tearing and a scratchy feeling, almost like there is sand in the eye. Mild cases typically result in swelling in the epithelial layer of the cornea and temporary blurred vision.

Why was oxygen deprivation a problem in those days?

Oxygen deprivation was a problem in those days because there was a solid barrier on the cornea. This was alleviated with the arrival of soft lenses and gas permeable rigid lenses that allow air to reach the eyes.

What happens if you don't have enough oxygen in your eye?

Without enough Oxygen the cornea will warp, become less transparent, less able to detect pain and can develop scars. Additionally, new blood vessels from the sclera (the white part of the eye) can grow into the cornea and cause further damage and scarring.

How to know if your eyes are not oxygenated?

Check with your optician to make sure you have the correct type to avoid damaging your eyes. Early symptoms of a lack of oxygen include dryness and irritation as well as blood shot eye. Solutions and moisturisers are available to help keep your eyes healthy and oxygenated.

Why does the retina pump up its veins?

Since the cornea is without blood vessels, the retina pumps up its veins in attempt to absorb more oxygen. This response can lead to other problems over time like corneal neovascularization and macular degeneration disease. The oxygen supply to the cornea is slightly less absorbed when contact lenses cover the cornea.

Why is the cornea transparent?

The cornea needs to be transparent so that light can pass through so there can be no blood vessels there, otherwise the light would be obscured. Without blood vessels the cornea must get it’s oxygen directly from the air. The oxygen first dissolves in the tears and then diffuses throughout the cornea to keep it healthy.

Can oxygen diffuse through the eye?

Some oxygen can diffuse through the aqueous humour within the eye but this is slow and limited. The main pathway is through the front of the eye so if this is restricted by your eyes being closed for extreme periods of time or via the use of the wrong type of contact lenses, then the cornea can become oxygen deprived.

Do contact lenses cover the cornea?

The oxygen supply to the cornea is slightly less absorbed when contact lenses cover the cornea. Contact lenses nowadays are a lot more permeable in order to allow more oxygen to pass through to the eye and some are designed to be in for long periods of time.

The Nervous System

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Everything we do consciously or unconsciously is intimately connected to the central nervous system (CNS), the central organizing power of the body. It is comprised of nerve cells in the brain and spinal cord. It receives, analyzes, and organizes all information coming from the five senses in every part of the body. It …
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The Optic Nerve

  • The optic nerve is responsible for carrying electrical impulses from the retina to our brain. Impulses that contain the information about what we see. The optic nerve is made up of ganglion nerve cells in the retina and glial cells. 1. Retinal ganglion cells receive information from the photoreceptors, and they transmit that information to different parts of the brain in the thalamus…
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Symptoms

  • The symptoms described here may not necessarily mean that you have optic nerve atrophy. However, if you experience one or more of these symptoms, contact your eye doctor for a complete exam. 1. Blurred vision 2. Decrease in visual functionsuch as a decrease in sharpness and clarity of vision (visual acuity) or decreases in side (peripheral) vision. Color vision and contr…
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Causes

  • Most commonly, optic nerve atrophy occurs without a known or proven cause. Causes leading to optic atrophy range from eye injury or trauma to systemic eye conditions and diseases. These include: 1. Optic neuritisoccurs when the optic nerve is inflammed due to autoimmune conditions, viral, fungal and bacterial infections, parasitic diseases, toxins, allergies, digestive problems, dia…
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Research

  • Though there are no specific studies on nutrients and this particular condition, there is extensive research on nutrients such as lutein, zeaxanthin and bilberry among others that have been shown to be essential for the health of the optic nerve. Based on these studies, Dr. Grossman has selected specific nutrients and products to help support the o...
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Footnote

  • 1. Nutrition & Optic Disease, Woon,C., et al, Neuro-Ophthalmology Department, University of Texas, Seminars in Ophthalmology 1995 Sep;10(3):195-202 Optic nerve & nervous system Types Symptoms Causes About the nervous system Treatment
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