Treatment FAQ

testosterone is rising 380 post lupron when do i go for another treatment

by Prof. Caesar Ledner MD Published 2 years ago Updated 2 years ago

What is the normal range of testosterone after Lupron therapy?

Time interval for recovery of testosterone after Lupron therapy. The median PSA of 7.8 ng/mL and highest value of 12.3 ng/mL are relatively low, considering 61% of patients had stage T3 disease or higher, and 16% were node positive. There were 10 major treatment violations in the ADT arm; eight men received no protocol therapy,...

How does Lupron affect testosterone levels?

When a person first takes Lupron, their testosterone levels may rise, or flare, before dropping to very low levels. For some people, particularly those with advanced prostate cancer, a testosterone flare can temporarily cause their symptoms to worsen. The symptoms of a testosterone flare can include:

How is Lupron administered for hormone replacement therapy?

Doctors often prescribe hormone therapies in combination with radiation therapy or following surgery. They administer Lupron by injecting it under a person’s skin, which they will do between once a month and once every 6 months. Because Lupron lowers testosterone levels, it can cause a range of side effects.

How long does it take for T to recover from Lupron?

Based on my experience it's not unusual to recover T that quickly. Last time after six months of just lupron my T went from <20 to 275 as well in a few months. I hope it does again this time after 13 months of ADT3 are over in Nov.

How long does it take for testosterone to return to normal after Lupron?

Conclusion: After LHRHa treatment and radiotherapy, the testosterone levels of most men had recovered to normal by 18-24 weeks after the last LHRHa injection.

What happens when Lupron treatment is over?

When a person first starts treatment with Lupron, they may have a testosterone flare. Later on, they may experience side effects due to having very low testosterone levels in their body. After treatment stops, testosterone levels begin to return to normal.

How long does it take Lupron to lower testosterone?

After beginning treatment, testosterone levels will drop within 2 to 4 weeks and the manufacturer has noted that levels have been shown to remain at castrate levels for more than 5 years.

How long does it take for testosterone levels to recover?

Most men will recover normal testosterone levels within 18 months according to the findings from studies that frequently involved fewer than 3 years of androgen deprivation therapy.

How long can you take Lupron injections?

Thinning of the bones may occur during therapy with LUPRON DEPOT, which may not be completely reversible in some patients. The duration of therapy with LUPRON DEPOT is limited to 3 months. The symptoms associated with fibroids will return after stopping therapy.

Which is better eligard vs Lupron?

The bottom line. Both Eligard and Lupron Depot can be used for advanced prostate cancer. These two brand-name medications contain the same ingredient — leuprolide. They're similarly effective and carry the same side effects.

How long does it take to recover from low testosterone?

Most men feel improvement in symptoms within four to six weeks of taking testosterone replacement therapy, although changes like increases in muscle mass may take from three to six months.

How fast does Lupron injection 3.75 take to work?

How long does it take to work? Lupron Depot begins working right away in your body. However, it usually takes about 2 to 4 weeks to see the full effects of the treatment (such as symptom relief) because your body goes through monthly cycles to produce hormones.

Will my testosterone levels return to normal after steroids?

It can take up to 4 months to restore natural testosterone levels after being on anabolic steroids for a long time. Withdrawal symptoms from steroids can include: fatigue. weight loss due to lowered appetite.

How long do you have to wait between steroid cycles?

» Cycling is the amount of time you use steroids and the amount of time you take a break from using steroids. » Recommended cycle 6-8 weeks. » Recommended recovery period is equal to or greater than your period of use.

How do I restart my testosterone?

Alternative treatmentsMaintain a healthy weight. Overweight men are more likely to have low testosterone levels. ... Exercise regularly. Sedentary men tend to have reduced levels of testosterone, as the body doesn't need as much. ... Sleep 7 to 8 hours every night. Lack of sleep affects the hormones in your body.

When do testosterone levels peak after injection?

Testosterone levels peak two to three days after the injection and then slowly drop until the next dose of the hormone is given. There are also testosterone patches that men can use. These patches can be placed on areas of the body such as the back, stomach, upper arm, or thigh.

Testosterone up only five weeks out of lupron

five weeks without lupron, I only did two months of lupron, which lowered my psa from 13 to 2.2 ,...

Testosterone and Lupron

My husbands oncologist wants my husband to get back on Lupron. DH’s testosterone is 1.2. Is there...

Testosterone level rising toward end of Lupron cycle

just over a month, my PSA level dropped from 8.8 to 1.0, and my testosterone level dropped to less...

Fast testosterone recovery after Zytiga mono-therapy

stopped Lupron June 2019 and remained on Zytiga alone. One 500mg dose with breakfast. Testosterone...

Close to divorce after prostatectomy

I am in shock and am grieving what I think is coming soon. My husband had a radical prostatectomy a year ago, one nerve spared, the cancer had left the capsule. He is young (52), and so far, his PSA has been 0 (checked four times a year). When he had the surgery, he developed an infection and had a terrible reaction to cipro.

Is there any chance of a sex life when taking Lupron

Hi All, It looks like I will be going on a six month course of Lupron and I am wondering what this does to your sex life. I believe your libido no longer exists so you have no desire, but what happens if you try to have an orgasm whilst on this drug.

Orgasm after prostatectomy - time for honesty!

Hey guys, I've been thinking about writing this post for quite some time now. In fact about 29 months since my nerve-sparing robotic surgery. It seems the thing that no one wants to talk about honestly- so here goes. Yes we all know that, despite no ejaculation, some of us (maybe nearly all of us) can still get an orgasm.

ANY thoughts: use of Ivermectin for prostate cancer in the lungs?

Prostate cancer nodules just in the lungs. PSA controlled by Bicalutamide at 0.6 BUT, would like to see the cancer gone! Are there any thoughts on use of Ivermectin (Stromectol) tablets? 12mg per day till cancer is gone? Thanks for your thoughts. Sign up to continue reading

How long does it take for testosterone to recover after ADT?

Although 89% of men recovered normal testosterone levels after 18 months , the fact that some men remain hypogonadal after 2 years of adjuvant ADT is an important piece of information in counseling patients.

How long does it take for T to come back?

He said it will take 24 months for it to be at a negligable level in my body. He said not to expect much in the raise of T or change of side effects for the first 3-6 months as the drug is still working. After that its effects will fall off rapidly and the T should start coming back quickly and the side effects reversing.

What are the questions about hormone therapy in metastatic prostate cancer?

The first key question: is the PSA response to initial ADT important to predict response and survival? The second question: does the type of ADT matter for maximal response? And the third question: is achieving a very low testosterone level really important in the setting of M1 metastatic prostate cancer?

Does itterac stop testosterone production?

itterac @itterac It's Lupron, not Lipton and it is used to stop production of testosterone that the cancer feeds on. A similar treatment is Eligard that does the same thing. Google Androgen deprivation therapy.

Is PSA nadir a predictor of response to hormone therapy?

In a study published by Fowler in 1995, PSA nadir was a very significant predictor of response to hormone therapy. In this study, after patient exclusions, 245 patients with localized and 78 patients with newly diagnosed metastatic prostate cancer were treated with ADT in the form of orchiectomy or LH-RH agonist.

Close to divorce after prostatectomy

I am in shock and am grieving what I think is coming soon. My husband had a radical prostatectomy a year ago, one nerve spared, the cancer had left the capsule. He is young (52), and so far, his PSA has been 0 (checked four times a year). When he had the surgery, he developed an infection and had a terrible reaction to cipro.

Is there any chance of a sex life when taking Lupron

Hi All, It looks like I will be going on a six month course of Lupron and I am wondering what this does to your sex life. I believe your libido no longer exists so you have no desire, but what happens if you try to have an orgasm whilst on this drug.

Orgasm after prostatectomy - time for honesty!

Hey guys, I've been thinking about writing this post for quite some time now. In fact about 29 months since my nerve-sparing robotic surgery. It seems the thing that no one wants to talk about honestly- so here goes. Yes we all know that, despite no ejaculation, some of us (maybe nearly all of us) can still get an orgasm.

ANY thoughts: use of Ivermectin for prostate cancer in the lungs?

Prostate cancer nodules just in the lungs. PSA controlled by Bicalutamide at 0.6 BUT, would like to see the cancer gone! Are there any thoughts on use of Ivermectin (Stromectol) tablets? 12mg per day till cancer is gone? Thanks for your thoughts. Sign up to continue reading

How long does it take for testosterone to recover after ADT?

However, at the two-year mark after ADT cessation, testosterone recovery varied according to age, duration of treatment, and baseline TT levels. Eight percent of patients remained castrate, 76 percent returned to a normal TT level (above 300 ng/dL), and 51 percent recovered baseline TT.

How old was the average prostate cancer patient before ADT?

The mean age of patients was 65, plus or minus (±) eight years. Primary prostate cancer treatment was a radical prostatectomy in 10 percent of patients, radiation therapy in 31 percent, a radical prostatectomy and radiation therapy in 55 percent, and primary ADT in 5 percent. (1)

How long does ADT last?

Despite the intention to reduce testosterone temporarily, androgen deprivation therapy (ADT) may lower it for prolonged periods in patients over the age of 65 or those who take ADT for more than six months, according to the results of our recent retrospective study.

How long does it take for TT levels to recover?

Overall, mean TT levels recovered over time to 216 ± 205 ng/dL, 275 ± 241 ng/dL, 292 ± 199 ng/dL, and 321 ± 193 ng/dL at six to 12 months, 12 to 18 months, 18 to 24 months, and more than 24 months after ADT cessation, respectively .

What is ADT treatment?

Androgen Deprivation Therapy. Testosterone stimulates the growth of prostate cancer, the most common nonskin cancer diagnosed in men. (2) ADT is used to lower serum testosterone to a castrate level in patients with metastatic or intermediate-high-risk prostat e cancer who undergo radiation therapy. It is also used as a neoadjuvant therapy on an ...

What is luporn used for?

Lupron is a type of hormone therapy for prostate cancer. It works by lowering the amount of testosterone in a person’s body, which helps slow the growth of cancer cells.

What is the name of the drug that blocks the production of testosterone in the testicles?

Lupron belongs to a class of drugs called luteinizing hormone-releasing hormone (LHRH) agonists. These medications block the production of LHRH in the body, which results in the testicles producing less testosterone.

What is the purpose of LHRH antagonists?

These drugs work in a similar way to LHRH agonists, but they lower testosterone levels much more quickly. LHRH antagonists are a form of chemical castration, and doctors use them to treat people with advanced prostate cancer.

What is the treatment for prostate cancer?

There are several treatment options for prostate cancer, including other LHRH agonists and various types of hormone therapy.

How can hormone therapy help with prostate cancer?

For people with prostate cancer, the aim of hormone therapy is to reduce testosterone levels in the body. Male hormones, such as testosterone, encourage the growth of prostate cancer cells. Therefore, lowering testosterone levels in the body can help slow the progression of prostate cancer. Doctors typically prescribe hormone therapy ...

What is the name of the drug that doctors use to treat prostate cancer?

Alternative treatment. Outlook. Summary. Lupron is the brand name for leuprolide acetate. This drug is a type of hormone therapy that doctors typically use in combination with other treatments to treat people with prostate cancer.

Can you take Lupron with prostate cancer?

Hormone therapies, such as Lupron, are often effective in combination with other treatments for people with late-stage prostate cancer. Many doctors do not recommend hormone therapy during the early stages of this disease.

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