Treatment FAQ

splenic hamartoma where to get treatment

by Lucinda Hessel Published 3 years ago Updated 2 years ago
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How do you get rid of a hamartoma?

Splenic hamartoma is a rare, benign vascular proliferation that is often found incidentally while working up other complaints or at autopsy. Women more commonly present with symptoms related to mass effect than men. Histologic findings consist of unorganized vascular channels of varying width, with intervening red pulp-like disorganized stroma ...

Can a hamartoma be left alone?

Splenic hamartoma (or splenoma) is a rare, benign, vascular tumor, often incidentally found at imaging, surgery or autopsy. Albeit usually asymptomatic and rare in children, when it occurs in the pediatric population it is more commonly symptomatic. ... TREATMENT & PROGNOSIS. As mentioned previously, splenic hamartoma usually remains ...

What is the best treatment for a splenic hamartoma?

Surgical procedures for splenic hamartoma include splenectomy, partial splenectomy, laparoscopic splenectomy, and hand-assisted laparoscopic splenectomy . In recent series, particularly in children, partial splenectomy has become the more popular surgical treatment of splenic masses due to the immunologic role of the spleen.

What are the symptoms of splenic hamartoma?

It can cause you to have breathing issues and may trigger pneumonia. In more severe cases, you may cough up blood or your lung tissue may collapse. Spleen. Splenic hamartomas, while …

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How do you treat hamartoma?

How are hypothalamic hamartomas treated?
  1. Resection surgery: A surgeon may perform brain surgery to remove the hamartoma. ...
  2. Stereotactic radiofrequency thermoablation: This form of ablation therapy uses heat to treat the hamartoma.
Nov 10, 2021

Can hamartomas become cancerous?

Sometimes they are left alone, but if they are causing symptoms due to their location, or if the diagnosis is uncertain, surgery to remove the tumor may be recommended. For some people, a hamartoma may be a sign of a gene mutation that can increase the risk of some cancers such as breast cancer and thyroid cancer.Nov 24, 2020

What causes splenic hamartoma?

The origin of splenic hamartomas is still controversial. Some consider them to be congenital malformations of the splenic red pulp, others to be neoplasms of the splenic red pulp or post-traumatic reactive lesions[2,9].

Can hamartomas grow?

Hamartomas are noncancerous growths that can appear anywhere on the body. While seen as harmless, these benign tumors can grow to large sizes and cause pressure on surrounding tissues. Depending on where they grow externally or internally, hamartomas can cause life-threatening symptoms.

How common are hamartomas?

Practice Essentials. Pulmonary hamartoma (PH) is the most common benign tumor of the lung and is the third most common cause of solitary pulmonary nodules. PHs occur mostly as peripheral solitary nodules and are incidentally detected on routine radiologic examinations, such as radiography and computed tomography (CT).Dec 17, 2018

How fast do hamartomas grow?

The nodular shadow increased in size from 12 × 15 mm to 15 × 20 mm within five months. The calculated tumor doubling time (TDT) in our case was approximately 132.2 days. A malignant tumor was strongly suspected based on the rapid growth, and tumorectomy was thus performed.

Can spleen hemangioma cause pain?

Hemangiomas are the most common benign primary neoplasm of spleen, yet they remain as a rare disorder. Less than 100 cases have been reported so far. The average age of presentation is 63 years. Most of the patients are asymptomatic, rest of the patients presenting with pain and a lump in the abdomen.Nov 7, 2017

Are splenic lesions cancerous?

The majority of such solid splenic nodules and masses are benign, with hemangioma being the most frequent diagnosis (8,9). However, CT imaging characteristics of benign and malignant splenic masses often overlap, making definitive differentiation difficult (8,10).Jan 24, 2018

Do spleen lesions cause pain?

Hamartomas are benign splenic neoplasms asymptomatic in most of the cases. Symptoms, when present, may either be related to the growth of the mass with abdominal discomfort and pain or be related to a hypersplenism syndrome.

Do hamartomas bleed?

Kidneys, stomach, spleen and other vascular organs

One general danger of hamartomas is that they may impinge into blood vessels, resulting in a risk of serious bleeding. Because a hamartoma typically lacks elastic tissue, it may lead to the formation of aneurysms and thus possible hemorrhage.

What is an example of hamartoma?

The literature describes several examples of hamartomas, including the following: Hemangioma and other vascular tumors that are not true neoplasms. Peutz-Jeghers polyp of the bowel, juvenile or retention. Polyp of the large bowel.Oct 12, 2021

Are hamartomas hereditary?

People with PTEN hamartoma tumor syndrome are at higher risk of developing breast, thyroid, kidney, uterus, colorectal, and skin cancer. PTEN hamartoma tumor syndrome is hereditary, which means it can be passed from parents to their children.

What is the procedure for a pulmonary hamartoma?

Procedures, when needed for pulmonary hamartomas include wedge resection (removal of the tumor and a wedge-shaped section of tissue surrounding the tumor), lobectomy (removal of one of the lobes of a lung), or pneumonectomy (removal of a lung). 14 .

Can hamartoma be left alone?

Sometimes they are left alone, but if they are causing symptoms due to their location, or if the diagnosis is uncertain, surgery to remove the tumor may be recommended. For some people, a hamartoma may be a sign of a gene mutation that can increase the risk of some cancers such as breast cancer and thyroid cancer.

Where is hamartoma found?

Douglas A. Nelson, MD. on November 24, 2020. A hamartoma is a benign tumor that may occur in the lungs, heart, skin, brain, breast, or other regions. 1  They are made up of abnormal but not cancerous cells similar to the cells that make up the tissue where they originate.

What is a hamartoma?

Douglas A. Nelson, MD. on November 24, 2020. A hamartoma is a benign tumor that may occur in the lungs, heart, skin, brain, breast, or other regions. 1  They are made up of abnormal but not cancerous cells similar to the cells that make up the tissue where they originate. Hamartomas can look similar to cancer on imaging studies, ...

Is a hamartoma tumor benign?

A hamartoma is a benign (non-cancerous) tumor that is made up of “normal” tissues that are found in the region in which they grow. For example, a lung (pulmonary) hamartoma is a growth of non-cancerous tissues including fat, connective tissue, and cartilage that is found in the regions of the lungs. 4 

Can hamartoma cause pain?

Hamartomas may not cause any symptoms, or they may cause discomfort due to pressure on nearby organs and tissues. 7  These symptoms will vary depending upon the location of the hamartoma. One of the most common "symptoms" is fear, as these tumors can look very much like cancer when found, especially on imaging tests.

Can a hamartoma be found in the lungs?

As noted above, lung (pulmonary) hamartomas are the most common benign tumors found in the lungs and are often discovered accidentally when chest imaging is done for some other reason. With the increased use of CT screening for lung cancer in people at risk, it’s likely that more people will be diagnosed with hamartomas in the future. 4 At the current time, hamartomas are the third most common cause of solitary pulmonary nodules in the lung.

Can a spleen hamartoma cause pain?

Spleen. Splenic hamartomas, while rare, trigger symptoms in more women than men. Hamartomas found on the spleen can cause pain and discomfort in the abdominal region.

What is the procedure for hamartoma?

A less invasive option, specifically for hypothalamic hamartoma growths, is gamma knife radiosurgery. This procedure uses multiple radiation beams to destroy the tumor cells. The concentrated beams will shrink the hamartoma growths.

Can a hamartoma tumor cause side effects?

Symptoms of hamartoma tumors. Hamartoma tumors sometimes grow without causing any symptoms. The location of the tumor, however, can trigger some harmful side effects. A common symptom from hamartoma growth is pressure, specifically when it begins pushing into other tissues or organs.

Can a hamartoma tumor grow without symptoms?

Hamartoma tumors sometimes grow without causing any symptoms. The location of the tumor, however, can trigger some harmful side effects. A common symptom from hamartoma growth is pressure, specifically when it begins pushing into other tissues or organs. If it grows, a hamartoma can change the appearance of the breast.

What happens if you have a hamartoma on your neck?

If they grow on your chest, you may experience some respiratory issues or a chronic cough. Heart. Hamartomas that grow on the heart can trigger heart failure symptoms. This is the most common heart tumor found in children. Breast.

What is a mammary hamartoma?

A mammary hamartoma is a benign tumor found on the breast. While these tumors can appear at any age, mammary hamartomas are typically found in women 35 years and older. Usually found by accident, they can grow to large sizes and cause breast deformities. Breast hamartomas can also cause swelling. Brain.

Can a hamartoma cause pneumonia?

Also referred to as pulmonary hamartomas, lung hamartomas are the most common benign lung tumors. It can cause you to have breathing issues and may trigger pneumonia. In more severe cases, you may cough up blood or your lung tissue may collapse. Spleen.

What is hamartoma in splenic parenchyma?

Hamartomas are solitary or multiple, round, well-circumscribed, unencapsulated bulging nodules compressing the adjacent normal splenic parenchyma and compounded by a mixture of normal splenic structures such as white and red pulp. Focal fibrosis and cystic areas can be seen.

Is a splenic hamartoma a nodule?

Splenic hamartomas are very rare lesions commonly found incidentally on imaging. They are most often solitary but may be present as multiple nodules in patients with tuberous scler osis or Wiskott-Aldrich syndrome.

What is a hamartoma?

Hamartomas are solitary or multiple, round, well-circumscribed, unencapsulated bulging nodules compressing the adjacent normal splenic parenchyma and compounded by a mixture of normal splenic structure s such as white and red pulp. Focal fibrosis and cystic areas can be seen.

What are the radiographic features of hamartomas?

Radiographic features. As hamartomas represent a focal disorganized overgrowth of splenic parenchyma, they tend to have similar echogenicity , attenuation , and signal intensity to the background normal parenchyma 7 .

Can hamartoma be treated with surgery?

For many patients with hypothalamic hamartoma, the related problems, most notably seizures, can be challenging to manage, but surgery can sometimes eradicate seizures. Many of the endocrine problems are treatable with medications. The seizure conditions require ongoing and diligent follow-up with a neurologist.

When do endocrinologists see a patient with hamartoma?

Endocrinologists most often encounter patients with hypothalamic hamartoma when they develop endocrine problems, most often early puberty. In some children, puberty may be the first recognized symptom.

Is hamartoma a tumor?

A hamartoma is a benign (non-cancerous) growth made up of an abnormal mixture of cells and tissues. A hypothalamic hamartoma is a tumor-like formation on the hypothalamus, the area at the base of the brain that controls the production and release of hormones by the pituitary gland. These hormones regulate a wide array of bodily functions, ...

Can hamartoma be inherited?

If they do, it is likely due to sporadic (not inherited) gene mutations. In the majority of cases, the person with hypothalamic hamartoma is the only one in the family to have the condition.

What are the symptoms of hamartoma?

Symptoms of hypothalamic hamartoma may include: Gelastic seizures (episodes of laughing with no apparent trigger) Other types of seizures, including seizures with altered awareness, with stiffening of the limbs, or with shaking. Problems with concentration, memory and learning.

What are the symptoms of hypothalamic hamartoma?

Symptoms of hypothalamic hamartoma may include: Gelastic seizures (episodes of laughing with no apparent trigger) Other types of seizures, including seizures with altered awareness, with stiffening of the limbs, or with shaking. Problems with concentration, memory and learning. Sudden episodes of rage, often with no apparent provocation.

Can a child have a hamartoma removed?

Other alternatives include removing or reducing the size of the hamartoma with surgery .

How rare is splenic hamartoma?

Splenic hamartoma is a rare benign lesion, with an incidence of 0.13% at autopsy 7 The average age of the occurrence of hamartoma and its diameter are older or greater in women than in men, 2 suggesting that hormonal factors may influence tumor growth. The diameter of the tumor ranges from a few millimeters to several centimeters. Being either multiple or singular, the multiplicity of the tumor has proved to be not related to the extent of hematologic symptoms. 2 Symptoms of hamartoma seem to depend on its size, 2,4,8,9 and symptomatic hamartoma is described to be of the red pulposal type. 4,8

Is splenic hamartoma a benign lesion?

Splenic hamartoma is a rare benign lesion, with an incidence of 0.13% at autopsy 7 The average age of the occurrence of hamartoma and its diameter are older or greater in women than in men, 2 suggesting that hormonal factors may influence tumor growth. The diameter of the tumor ranges from a few millimeters to several centimeters. Being either multiple or singular, the multiplicity of the tumor has proved to be not related to the extent of hematologic symptoms. 2 Symptoms of hamartoma seem to depend on its size, 2,4,8,9 and symptomatic hamartoma is described to be of the red pulposal type. 4,8

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Symptoms

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Hamartomas can look similar to cancer on imaging studies, and for this reason, can be very frightening. In some regions of the body, they may not cause any symptoms, or even regress in time, whereas in others, it can cause complications. Hamartomas may not cause any symptoms, or they may cause discomfort due t…
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Causes

  • They may also occur as part of syndromes that predispose people to cancer in several different organs. Often, there are no symptoms associated with a hamartoma, and they are found incidentally when a test is ordered for another reason, but when they cause symptoms, it is often related to the location where they occur. Nobody is sure what causes hamartomas, although the…
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Definition

  • A hamartoma is a benign (non-cancerous) tumor that is made up of normal tissues that are found in the region in which they grow. For example, a lung (pulmonary) hamartoma is a growth of non-cancerous tissues including fat, connective tissue, and cartilage that is found in the regions of the lungs.
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Epidemiology

  • The difference between hamartomas and normal tissue is that hamartomas grow in a disorganized mass. Most hamartomas grow slowly, at a rate similar to normal tissues. They are more common in men than in women. While some are hereditary, nobody knows for sure what causes many of these growths to occur. Many people have never heard of hamartomas, but the…
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Prevention

  • If you have recently had CT screening and your doctor is considering that you may have a benign tumor such as a hamartoma, learn about what happens when you have a nodule on screening and the chances that it's cancer. For some people, a hamartoma may be a sign of a gene mutation that can increase the risk of some cancers such as breast cancer and thyroid cancer. It's import…
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Pathophysiology

  • Unlike malignant (cancerous) tumors, hamartomas do not usually spread to other regions of the body. That said, depending on their location, they can cause damage by placing pressure on nearby structures.
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Diagnosis

  • Its also important to note that people with Cowdens disease (a syndrome in which people have multiple hamartomas) are more likely to develop cancers, especially of the breast and thyroid. So even though hamartomas are benign, your doctor may want to do a thorough examination and possibly imaging studies to rule out the presence of cancer. Syndromes such as Cowden's syndr…
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Treatment

  • Treatment options for a hamartoma will depend largely on the location of the tumor and whether or not it is causing symptoms. If hamartomas are not causing symptoms, your doctor may recommend that the tumor be left alone and observed over time. Hamartomas are benign (non-cancerous) tumors that will not spread to other parts of your body. Sometimes they are left alon…
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Risks

  • There has been much discussion over whether hamartomas should be observed or removed surgically. A 2015 review of studies attempted to clarify this issue by weighing the risk of mortality and complications due to surgery with the risk of recurrence of the tumor.
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