seminoma treatment in singapore which best

by Earline Ruecker Published 2 years ago Updated 2 years ago

Treatment is typically chemotherapy with 4 cycles of EP (etoposide and cisplatin) or 3 or 4 cycles of BEP (bleomycin, etoposide, and cisplatin). Another option might be VIP (etoposide, ifosfamide, and cisplatin) for 4 cycles. Radiation therapy is generally not used for stage IIC seminoma. Non-seminomas Stage I non-seminomas

Full Answer

What are the treatment options for seminoma?

A retrospective analysis was done of 49 patients treated for testicular seminoma over a 15-year period between January 1980 and April 1995 at the Department of Therapeutic Radiology, Singapore General Hospital. Their mean age was 39 years and their median period of follow-up was 67 months. Using the …

Who specializes in the best hemorrhoid treatment in Singapore?

Aug 16, 2018 · Evaluations consist of chest X-rays, CT scans, and checking for cancer markers. A review of previously published studies found that 17% of seminoma patients managed by surveillance experienced a cancer recurrence. Nearly all of these patients were cured with subsequent treatment.3. The advantage of surveillance is that the 85% of patients who ...

How many radiation treatments do I need for seminoma?

Feb 22, 2016 · The current management options for CSI seminomas include adjuvant radiotherapy (ART), AS, and ACT. ART has been the preferred treatment modality for a long time, but concerns regarding its side effects, such as risks of cardiovascular disease and secondary malignancies, resulted in a significant change in the concept of ART.

Is there a cure for Stage 3 non-seminoma cancer?

Chemotherapy: This is typically the preferred treatment. It is usually either 4 cycles of EP (etoposide and cisplatin) or 3 cycles of BEP (bleomycin, etoposide, and cisplatin). Radiation: This may be an option instead of chemo if the lymph nodes aren't enlarged from cancer spread.

What is the treatment for seminoma?

Stage IIC seminomas

Treatment is typically chemotherapy with 4 cycles of EP (etoposide and cisplatin) or 3 or 4 cycles of BEP (bleomycin, etoposide, and cisplatin). Another option might be VIP (etoposide, ifosfamide, and cisplatin) for 4 cycles. Radiation therapy is generally not used for stage IIC seminoma.Sep 4, 2019

What is better seminoma or nonseminoma?

Seminomas are very sensitive to radiation therapy. Nonseminoma: This more common type of testicular cancer tends to grow more quickly than seminomas. Nonseminoma tumors are often made up of more than one type of cell, and are identified according to these different cell types: Choriocarcinoma (rare)May 27, 2020

Is seminoma cancer curable?

Chemotherapy May Be as Effective as Radiation Therapy after Surgery. Stage I seminoma is a highly curable cancer, with cure rates in excess of 95%.

Is seminoma cured by radiation?

Recurrences of stage I seminoma can almost always be cured with radiation therapy, although a few patients will need chemotherapy. Surveillance. Surveillance is the standard method of managing stage I seminoma.

Is seminoma or non seminoma more common?

Seminomas may be slightly more common, accounting for about 55 percent of all testicular germ cell tumors in the United States, according to a 2014 study in Andrology. Non-seminomas account for about 44 percent of testicular germ cell tumors, according to the same study.

Can a seminoma return?

In seminomas, recurrences still occur until 3 years. Recurrences after 3 years are rare, occurring in less than 5% of people. Because of the risk of recurrence, you'll need regular tests to check if the cancer has returned.

What causes seminoma?

Later in development, germ cells in males are supposed to mature into sperm-producing cells within the testicles. If the germ cells don't mature as they are supposed to, they can sometimes change and multiply uncontrollably to form a seminoma or non-seminoma.May 6, 2022

Can you live a long life after testicular cancer?

more than 95 out of 100 men (more than 95%) will survive their cancer for 1 year or more after they are diagnosed. 95 out of 100 men (95%) will survive their cancer for 5 years or more after diagnosis. around 90 out of 100 men (around 90%) will survive their cancer for 10 years or more after diagnosis.

Do you lose your hair with chemo for testicular cancer?

Another common side effect of chemotherapy is hair loss, which many of the men associated with cancer. After about three weeks of chemotherapy they lost all their body hair, including eyebrows.

What is the prognosis of seminoma?

The 3-year survival rate for patients diagnosed with typical testicular seminoma was 100%, 93.8% for cases with testicular seminoma combined with embryonal carcinoma, and 84.6% for those with testicular seminoma combined with embryonal carcinoma and teratoma.Dec 30, 2015

What is metastatic seminoma?

Abstract. Retroperitoneal metastasis of seminoma often occurs in the higher stage through lymph nodes. Generally, seminoma expresses specific germ cell markers while being negative for carcinoma markers. We present a unique case of cytokeratin positive seminoma initially presented as retroperitoneal metastasis.

What is retroperitoneal surgery?

Retroperitoneal lymph node dissection (RPLND) is a surgical procedure that removes lymph nodes from the abdomen. Lymph nodes are small structures that help filter the body and fight disease. They are a part of the immune system.Sep 23, 2019

Carcinoma in Situ (Stage 0) Testicular Tumors

In this stage, the cancer has not spread outside the testicle, and your tumor marker levels (like HCG and AFP) are not elevated. If CIS is diagnose...

Stage III Seminomas and Non-Seminomas

Even though stage III tumors have spread by the time they are found, most of them can still be cured.Both stage III seminomas and non-seminomas are...

Recurrent Testicular Cancer

If the cancer goes away with treatment and then comes back, it's said to have recurred or relapsed. If this happens, it’s usually within the first...

Sertoli Cell and Leydig Cell Tumors

Typically, radical inguinal orchiectomy is the treatment for Sertoli cell and Leydig cell tumors. Radiation therapy and chemo generally don't work...

More Treatment Information For Testicular Cancer

For more details on treatment options – including some that may not be addressed here – the National Comprehensive Cancer Network (NCCN) and the Na...

What is stage 2 testicular seminoma?

Stage II testicular seminoma involves the testis and the retroperitoneal lymph nodes and is curable with surgery, and adjuvant treatment with radiation and or systemic therapy. Retroperitoneal lymph node involvement is further characterized by the number of nodes involved and the size of involved nodes. Patients with Stage II seminoma are often divided into “bulky” and “non-bulky” for treatment

What is the progress made in the treatment of testicular cancer?

The progress that has been made in the treatment of testicular cancer has resulted from improved development of chemotherapy and radiation treatments in patients with more advanced stages of cancer and participation in clinical trials. Future progress in the treatment of testicular cancer will result from continued participation in appropriate clinical trials.

What is the most commonly administered chemotherapy for cancer?

The most frequently administered chemotherapy combinations include bleomycin, etoposide and Platinol® (BEP) for 3 courses or etoposide and Platinol® (EP) for 4 courses in good-prognosis patients. Over 90% of patients who relapse after surgery or radiation therapy can be cured with chemotherapy.

What is the treatment for cancer after orchiectomy?

The delivery of cancer treatment following local treatment with surgery is referred to as “adjuvant” therapy and may include chemotherapy or radiation therapy. Following orchiectomy, 15-50% of patients will experience cancer recurrence if they are not treated with adjuvant therapy. By administering chemotherapy or radiation therapy to the retroperitoneal and inguinal lymph nodes after surgery, the chance of cancer recurrence can almost be completely eliminated. The choice of receiving radiation therapy or chemotherapy is influenced by side effects, convenience and whether the cancer is bulky.

What is the cure rate for non-bulky cancer?

This results in a cure rate of more than 90% . One of the controversies in management of Stage II seminoma is how much surveillance is necessary in patients who have received radiation therapy since the recurrence rate is so low.

What is an acceptable alternative to adjuvant therapy?

An acceptable alternative to adjuvant therapy is to give no additional treatment after surgery and to perform surveillance. The principle of surveillance is to perform frequent evaluations after surgery in order to detect an early cancer recurrence and then initiate further treatment. Evaluations consist of chest X-rays, CT scans, and checking for cancer markers.

Is seminoma a primary cancer?

A stage I seminoma is a primary cancer that is limited to the testes and is curable with surgical orchiectomy alone in more than 95% of individuals.

How often do you have to watch for stage 2 seminoma?

The doctor will then watch closely (every 3 to 6 months) for any signs that the cancer has come back .

What is the treatment for cancer after chemo?

If a man’s cancer recurs after chemo or if treatment is no longer working, he will be treated with different chemo, which typically includes ifosfamide, cisplatin, and either etoposide, paclitaxel, or vinblastine.

What is the procedure to remove lymph nodes?

If tumor marker levels are normal, there are 2 main options: Retroperitoneal lymph node dissection (RPLND): This is surgery to remove the lymph nodes at the back of the abdomen. If the lymph nodes that were removed contain cancer, chemo (typically for 2 cycles) might be given.

What is stage 0 testicular cancer?

Carcinoma in situ (stage 0) testicular tumors. In this stage, the cancer has not spread outside the testicle, and tumor marker levels (like HCG and AFP) are not elevated. If CIS is diagnosed after surgery removes the testicle, no other treatment is needed. If CIS is found after a testicular biopsy (such as for fertility problems), ...

Where are tumors left after treatment?

Sometimes a few tumors might be left after treatment. These are most often in the lung or in the retroperitoneal lymph nodes. Further treatment at this point depends on the type of cancer:

Can you get a cure for a stage 3 non-seminoma?

A stage III non-seminoma tumor that remains after treatment is usually removed surgically, which may result in a cure. If cancer is found in the tumors removed, you might need more chemo, maybe with different drugs. After this, surgery might be done to take out any tumors that remain.

Can stage 3 cancer be cured?

Even though stage III cancers have spread by the time they are found, most of them can still be cured.

How to confirm seminoma?

While all of the above tests (especially the ultrasound) point towards a diagnosis of testicular cancer, the only way to confirm a seminoma is to obtain a tissue sample.

How to tell if you have a seminoma?

The most typical symptom of a seminoma is the finding of a painless lump, mass, nodule, or swelling on one testicle. 3 . Other symptoms may include: A feeling of heaviness or dull achiness in the scrotum or lower abdomen. Breast tenderness and growth (due to a hormone secreted by the tumor)

How many patients with testicular seminoma have mild increases in HCG?

About 30% of patients with testicular seminoma have mild increases of hCG. 6

What are the two types of testicular seminomas?

There are two main sub-types of testicular seminomas—classical and spermatocytic seminomas. Classic seminoma is by far the most common sub-type and usually occurs in men between the ages of 25 and 45 years.

How does seminoma form?

A seminoma arises from germ cells that grow uncontrollably. Germ cells are the cells that form an embryo in a mother's womb. Later on in development, germ cells are supposed to mature into sperm-producing cells within the male testicles.

Where do seminomas occur?

The vast majority of seminomas occur in the testicle. Very rarely, a seminoma may develop in other areas of the body, such as the mediastinum (chest area) or the retroperitoneum (abdominal area). 1

How long do you have to monitor for stage 1 seminoma?

After surgery, most patients can be followed by active surveillance, which means close monitoring for up to 10 years (e.g., getting physical exams, imaging tests, and blood tests every few months, to start). 10 .

What is the Lim Clinic?

Lim Clinic is yet another place offering affordable customised skin treatments. It can handle all types of aesthetic issues, from hair loss to skin pigmentation by using laser treatments, fillers, and skincare products.

What is the best treatment for acne scars?

To treat pigmentation and acne scars, Sozo Clinic uses advanced PicoPlus laser treatment . This treatment offers better effectiveness with fewer risks to side effects like inflammation and burning.

Does Clifford Clinic have microdermabrasion?

The Clifford Clinic offers dermabrasion treatments to address pigmentation issues. Its microdermabrasion treatment shows positive results after just one 60-minute session.

Is S Aesthetics Clinic open?

S Aesthetics Clinic is famous for its pain-free treatments thanks to its numbing creams and gentle staff. One of the best things about this clinic is that it is open even on public holidays!

Does Lux Aesthetic Clinic offer chemical peels?

Additionally, Lux Aesthetic Clinic also offers chemical peels, so clients can continue and maintain their even skin. With these services and its customer treatment, the clinic forms long-term relationships with its clients.

Does Only Aesthetics have pigmentation treatments?

Aside from its custom products and services, ONLY Aesthetics also prides itself on being a multi-awarded cosmetic clinic.

Is Sozo Clinic a good option?

Now if you’re a busy workaholic who just can’t find the perfect time for your aesthetic needs, then Sozo Clinic may be a viable option for you. This clinic offers treatments with minimal downtime and quick recovery so you can go out and about as soon as possible.

Who is the best dermatologist in Singapore?

If you are looking for the best dermatologist in Singapore for acne that’s trusted and reputable, The Clifford Clinic already has over 18 years of experience. With its two doctors, Dr Gerard Ee and Dr Chow Yuen Ho, the clinic provides all types of treatments, from oral and topical medications to facial treatments.

Who is the doctor at S Aesthetics?

It has two doctors on-site, with one of them, Dr Sii Sik Liong, being an expert in botox fillers and medical laser treatments.

What is the best hospital for hemorrhoids in Singapore?

Tonyo Medical Hall. Tonyo Medical Hall is the ideal option for patients who don’t like to go under the knife because it specialises in non-surgical treatments for hemorrhoids, piles, anal fissures, and many more. This is why we call it one of the best hemorrhoids clinics in Singapore.

What time does a colorectal surgeon work in Singapore?

OPERATING HOURS. Mon–Fri: 9:00AM – 5:00PM. Saturday: 9:00AM – 12:30PM. Colorectal Surgeon Singapore is a clinic that offers a wide range of services, in order to provide customised care that is able to meet their client’s health needs.

What time does Tonyo Medical Hall open?

OPERATING HOURS. Monday – Friday, 9:00 AM – 5:00 PM. Tonyo Medical Hall is the ideal option for patients who don’t like to go under the knife because it specialises in non-surgical treatments for hemorrhoids, piles, anal fissures, and many more. This is why we call it one of the best hemorrhoids clinics in Singapore.

What time does HG surgery open?

OPERATING HOURS. Monday – Friday, 8:00 AM – 5:00 PM. HG Surgical Specialists is among the clinics on the island accredited by Medisave, allowing patients to have their medical bills expedited. It’s also composed of a large team of skilled and trained surgeons and specialists.

How to treat stage 2 testicular cancer?

Treatment of seminoma may include the following: When the tumor is 5 centimeters or smaller: Surgery to remove the testicle, followed by radiation therapy to lymph nodes in the abdomen and pelvis.

Can testicular cancer be cured?

Type of cancer. Size of the tumor. Number and size of retroperitoneal lymph nodes. Testicular cancer can usually be cured in patients who receive ad juvant chemotherapy or radiation therapy after their primary treatment .

Is a testicular tumor a nonseminoma?

Seminomas are more sensitive to radiation. A testicular tumor that contains both seminoma and nonseminoma cells is treated as a nonseminoma. Testicular cancer is the most common cancer in men 20 to 35 years old.