At the time of this writing, SSRI
Selective serotonin reuptake inhibitor
Selective serotonin reuptake inhibitors are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder and anxiety disorders. The exact mechanism of action of SSRIs is unknown. They are believed to increase the extracellular level of the neurotransmitter ser…
What is Prozac used to treat?
Prozac is used to treat major depressive disorder, bulimia nervosa (an eating disorder), obsessive-compulsive disorder, and panic disorder. ... Prozac is sometimes used together with another medication called olanzapine (Zyprexa) to treat manic depression caused by bipolar disorder.
How did Prozac change the world of Psychiatry?
The Story of Prozac: A Landmark Drug in Psychiatry Prozac changed the way we think about depression and the human mind. Posted March 1, 2020 |Reviewed by Gary Drevitch Share Tweet Email THE BASICS What Is Psychiatry? Find a therapist near me
How effective is Prozac for obsessive compulsive disorder?
In treatment, one group was given Prozac with no formal therapy, the other behavior therapy, in the form of exercises designed to prevent their compulsiveness, with no drugs. After 10 weeks, scans of their brains were compared with those taken at the beginning of treatment. Approximately two-thirds of each group improved.
Is Prozac the most popular antidepressant?
It is the most widely used antidepressant in history and has been prescribed to 54 million people worldwide. However, despite its popularity, there are many reports of people abusing Prozac and taking it to solve personal problems, rather than as a treatment for clinical depression.
What disorders are treated with Prozac?
It is approved for the treatment of major depressive disorder (MDD), obsessive compulsive disorder (OCD), panic disorder, bulimia nervosa, and premenstrual dysphoric disorder (PMDD).
What is Prozac most commonly used for?
Fluoxetine is used to treat depression, panic attacks, obsessive compulsive disorder, a certain eating disorder (bulimia), and a severe form of premenstrual syndrome (premenstrual dysphoric disorder).
Who does Prozac work best for?
Many children and teens with anxiety and depression find that Prozac helps them manage their symptoms safely. Prozac is FDA-approved to treat patients ages 7-18 with obsessive-compulsive disorder and pediatric patients ages 8-18 who have major depressive disorder (MDD).
What type of anxiety does Prozac treat?
It's approved by the Food and Drug Administration (FDA) to treat major depressive disorder, obsessive compulsive disorder (OCD), bulimia, and panic disorder, but doctors also prescribe Prozac off-label to manage other types of anxiety disorders.
Does Prozac help with bipolar?
Prozac (fluoxetine) is a type of antidepressant known as a selective serotonin reuptake inhibitor (SSRI), which is often used for the treatment of depression, bipolar disorder, and other mental illnesses.
Does Prozac help with ADHD?
Many clinicians opt for fluoxetine (Prozac), since it has no effect on ADHD and its long duration in the body makes it an ideal drug for patients who forget to take it. Some clinicians may use a second-line medication alone for cases of mild to moderate depression plus ADHD.
How does Prozac work for OCD?
When your brain is suffering from OCD or depression, the levels of serotonin in your brain are off-kilter, causing you to experience those painful symptoms. SSRIs like Prozac help to correct this chemical imbalance of serotonin in the brain.
Does Prozac help social anxiety?
Studies have found that antidepressants -- particularly the selective serotonin reuptake inhibitors (SSRIs) like Prozac -- help relieve social phobia. Through cognitive behavioral therapy (a form of psychotherapy) people learn to change negative thoughts and behaviors that feed the phobia, and they learn social skills.
Did Prozac help you?
User Reviews for Prozac to treat Anxiety and Stress. Prozac has an average rating of 7.3 out of 10 from a total of 356 ratings for the treatment of Anxiety and Stress. 67% of reviewers reported a positive experience, while 19% reported a negative experience.
Is Prozac good for generalized anxiety disorder?
Few studies directly compare Zoloft and Prozac in treating anxiety. However, they appear to be equally effective in improving anxiety in studies involving depression. One study that compared the 2 for treatment of major depression found that the drugs both improved symptoms in patients, including anxiety.
When should you take Prozac?
For example, the manufacturer of Prozac (fluoxetine) recommends it be taken in the morning because it can make some people feel more energized, especially at the beginning of treatment.
Before Taking This Medicine
Do not use Prozac if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarbo...
How Should I Take Prozac?
Take Prozac exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose....
What Happens If I Miss A Dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to...
What Should I Avoid While Taking Prozac?
Drinking alcohol can increase certain side effects of Prozac.See also: Prozac and alcohol (in more detail)Ask your doctor before taking a nonsteroi...
What Other Drugs Will Affect Prozac?
Taking Prozac with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before taking...
How long does it take for Prozac to work?
It may take up to 4 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve. Do not stop using Prozac suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.
How old do you have to be to take Prozac?
Prozac is not approved for use by anyone younger than 18 years old.
How long after stopping Prozac can I take thioridazine?
You must wait 5 weeks after stopping Prozac before you can take thioridazine or an MAOI. Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Prozac could impair judgment, thinking, or motor skills.
What is the best medication to treat bipolar disorder?
Prozac is sometimes used together with another medication called olanzapine (Zyprexa) to treat manic depression caused by bipolar disorder. This combination is also used to treat depression after at least 2 other medications have been tried without successful treatment of symptoms.
What to do if you miss Prozac?
If you miss a dose of Prozac Weekly, take the missed dose as soon as you remember and take the next dose 7 days later. However, if it is almost time for the next regularly scheduled weekly dose, skip the missed dose and take the next one as directed. Do not take extra medicine to make up the missed dose.
How to tell if you are pregnant with fluoxetine?
If you are breastfeeding, tell your doctor if you notice agitation, fussiness, feeding problems, or poor weight gain in the nursing baby.
Is Prozac safe for you?
To make sure Prozac is safe for you, tell your doctor if you have ever had: cirrhosis of the liver; urination problems;
What is the role of Prozac in mental health?
Perhaps of equal significance is Prozac's role in reshaping the public perception of mental disorders, redefining the concept of clinical depression, and reorienting psychiatry —at least temporarily—away from psychotherapy and toward biological treatment.
When was Prozac introduced?
Among these gamechangers undoubtedly lies the introduction of fluoxetine (Prozac) by Eli Lilly and Company in 1987. The search for a drug specifically targeting depression began with the work of the pioneering psychopharmacologist Nathan S. Kline in the 1950s. Kline, director of research at Rockland Hospital in Rockland County, New York, ...
What was the best antidepressant in 1990?
By 1990, much to Lilly's surprise, Prozac became the best-selling antidepressant of all time. With Prozac's mass success, a new type of depressed patient emerged: the mildly depressed (see Shorter, 2013).
What was the consensus in psychiatry in the 1990s?
As psychiatrist Daniel Carlat described in his controversial 2010 book, Unhinged: The Trouble with Psychiatry, the general consensus in psychiatry at the time was that biology held all the answers to the problem of mental illness. Carlat, trained in the early 1990s at the Harvard-affiliated Massachusetts General Hospital, described his experience in psychiatric residency as one that emphasized biological understanding and treatment and minimized—and, at times, confidently dismissed—the role of psychotherapy. Claims of Freud's demise—clearly premature—were being asserted, both inside and outside of the profession.
What are some of the most important discoveries in psychiatry?
In the history of psychiatry, a few discoveries can be said to have forever changed the landscape of the discipline: the development of psychoanalysis by Freud; the discovery of electroconvulsive therapy by Ugo Cerletti; the (re-)discovery of lithium's effectiveness in bipo larmood disorders by John Cade. Among these gamechangers undoubtedly lies the introduction of fluoxetine (Prozac) by Eli Lilly and Company in 1987.
When was fluoxetine first discovered?
On July 24, 1972, they found one. Eli Lilly originally identified the chemical as "Lilly 110140" but renamed it "fluoxetine" in 1975. A couple of years later, the company filed an application with the FDA to investigate fluoxetine's potential as a treatment for clinical depression. Initial expectations were modest.
When did norepinephrine become a focus in psychiatry?
For a period of time in the 1960s and 1970s, norepinephrine took center stage as psychiatry's focus in mood disorders. Serotonin's role was minimized and seen only as ancillary to norepinephrine. This all changed with Prozac. In the early 1970s, the pharmaceutical company Eli Lilly began to investigate the possibility of developing an ...
How long does it take for Prozac to work?
Improvements are often noticed days to weeks after starting Prozac, but it can actually take up to several months before you experience the full effect. 7 .
What is the best medication for panic disorder?
If you have panic disorder, you will likely be treated with antidepressant medication. One popular antidepressant used to treat panic disorder and other conditions is Prozac (fluoxetine). 1 .
What is the black box warning for SSRIs?
Black box warning: In 2007, the Food and Drug Administration (FDA) issued a black box warning for all SSRIs. 10 The FDA cautioned that SSRI usage has the potential to increase thoughts and behaviors related to suicide.
When did SSRIs become available?
SSRIs first became available in the United States in the 1980s and quickly came to be the most commonly prescribed type of antidepressant medication. 2 Due to the effectiveness, safety, and limited side effects of SSRIs, their popularity continued to grow.
Is Prozac good for depression?
Doctors initially prescribed Prozac to treat depression. However, research has shown that it can treat a variety of mental health and medical conditions. 3 Currently, Prozac is used in the treatment of major depressive disorder, bipolar disorder, eating disorders, chronic pain, migraines, irritable bowel syndrome, obsessive-compulsive disorder , ...
Does Prozac cover all potential variables?
The information provided here is simply an overview regarding the use of Prozac for panic disorder. This information does not cover all potential variables, including possible side effects, precautions, and contraindications. Always talk to your medical provider about any questions and concerns you may have about your prescription.
Can you give a baby Prozac?
Pregnancy/nursing: Prozac can be passed on to unborn babies during pregnancy or through breast milk when a baby is nursing. 12 If you're pregnant or nursing, consult with your doctor about the possible risks of taking Prozac.
What is fluoxetine used for?
It is recurrently the paradigm for the development of any new therapy in the treatment of depression. Many controlled studies and meta-analyses were performed on Fluoxetine, to improve the understanding of its real impact in the psychiatric area. The main objective of this review is to assess the quality and the results reported in the meta-analyses published on Fluoxetine.
How many articles were identified as suitable for fluoxetine?
All meta-analyses, where fluoxetine was directly compared with placebo or with other drugs, were eligible for this paper. A total of 25 articles were identified as suitable.
How many articles have fluoxetine been published in?
Fluoxetine has been widely studied and described in the scientific literature; its use has been reported in over 8,500 articles present in the most important literature databases (Medline, Embase).
How long does fluoxetine stay in your system?
The parent compound, fluoxetine, has an elimination half-life of 1 to 4 days, whereas the active metabolite, norfluoxetine, has an half-life of 7 to 10 days[3]. This extended half-life appears to protect against sporadic noncompliance [2] and against the occurrence of withdrawal phenomena.
Is fluoxetine a drug?
Fluoxetine can be considered a drug successfully used in several diseases for its favorable safety/efficacy ratio. As the response rate of mentally ill patients is strictly related to each patient's personal characteristics, any new drug in this area, will have to be developed under these considerations.
Is fluoxetine effective for bulimia?
The meta-analysis available on the use of Fluoxetine in the treatment of bulimia nervosa shows that the drug is as effective as other agents with fewer patients dropping out of treatment.
Is fluoxetine safe for depression?
Data, based on a group of 9087 patients, who were included in 87 different randomized clinical trials, confirms that fluoxetine is safe and effective in the treatment of depression from the first week of therapy. Fluoxetine's main advantage over previously available antidepressants (TCAs) was its favorable safety profile, that reduced the incidence of early drop-outs and improved patient's compliance, associated with a comparable efficacy on depressive symptoms. In these patients, Fluoxetine has proven to be more effective than placebo from the first week of therapy.
Fluoxetine
Fluoxetine is a selective serotonin reuptake inhibitor (SSRI). This means that its essential action is to increase serotonin levels. This neurotransmitter enhances our well-being and brain balance.
Usage
We know that it’s effective in the treatment of depression, obsessive-compulsive disorders, and bulimia. Furthermore, it’s a good antiviral, and a valuable resource in enhancing neurogenesis. It’s also useful in many other clinical cases. For example:
Side-effects
As we mentioned earlier, until the arrival of fluoxetine, the treatment of depression was limited to tricyclic antidepressants. The side-effects of these drugs, as anyone who received treatment for depression in the 1970s will know, were quite adverse. However, with drugs like Prozac, everything changed.
How does Prozac help with anxiety?
When taken correctly under the supervision of a doctor, Prozac can improve mood, sleep, appetite, energy levels, and decrease feelings of depression, fear, anxiety, and panic. Prozac can be used to treat adults and children over the age of 10 and is available in several different forms, including liquid, tablet, ...
What is the purpose of Prozac?
Prozac is a selective serotonin reuptake inhibitor (SSRI) that is meant to treat depression, obsessive-compulsive disorder, panic disorder, and multiple other anxiety disorders. Being an SSRI, Prozac works by stopping the brain from reabsorbing naturally appearing serotonin. This helps the brain maintain it’s serotonin levels, ...
What are some examples of Prozac abuse?
Examples of Prozac abuse may include: Taking Prozac with other drugs or alcohol. Taking someone else’s Prozac prescription. Faking symptoms to get a Prozac prescription. “Doctor shopping” and getting multiple Prozac prescriptions. Taking larger or more frequent doses of Prozac than needed.
How does Prozac work?
As a selective serotonin reuptake inhibitor, also known as an SSRI, Prozac works by balancing the chemicals in the brain and inhibiting the absorption of the neurotransmitter serotonin. As a result, users can maintain a more positive and stable mood.
What are the signs of a person's addiction to Prozac?
Signs of psychological dependence and addiction to Prozac may include: Aggressive behavior. Irritability. Problems sleeping.
When was Prozac first used?
Introduced in 1986, Prozac was initially hailed as a miracle cure for depression. It is the most widely used antidepressant in history and has been prescribed to 54 million people worldwide.
Is Prozac addictive?
Although Prozac is not classified as an addictive drug, it alters the mood of users and therefore, may be psychologically addictive. It can also cause suicidal thoughts and behaviors in children and young adults under the age of 25. Other brand names for fluoxetine include: Sarafem.