Treatment FAQ

propranolol is used in the treatment of which disorders?

by Arch Beahan Published 2 years ago Updated 2 years ago
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About propranolol
It's used to treat heart problems, help with anxiety and prevent migraines. If you have a heart problem, you can take propranolol to: treat high blood pressure
high blood pressure
Known causes of high blood pressure

kidney disease. diabetes. long-term kidney infections. obstructive sleep apnoea – where the walls of the throat relax and narrow during sleep, interrupting normal breathing. glomerulonephritis – damage to the tiny filters inside the kidneys.
https://www.nhs.uk › high-blood-pressure-hypertension › causes
. treat conditions that cause an irregular heartbeat (arrhythmia), like atrial fibrillation.

What propanol is used for?

Propranolol is used to treat tremors, angina (chest pain), hypertension (high blood pressure), heart rhythm disorders, and other heart or circulatory conditions. It is also used to treat or prevent heart attack, and to reduce the severity and frequency of migraine headaches.

What type of anxiety does propranolol treat?

Propranolol is sometimes used off-label to help with certain kinds of anxiety, such as performance anxiety. Propranolol can help with physical performance anxiety symptoms, including dry mouth, nausea, fast pulse, or shaky hands. It's FDA-approved to treat many other conditions, such as high blood pressure and tremors.

Is propranolol used for panic disorder?

Because propranolol is so effective at reducing certain symptoms associated with anxiety—like sweating and rapid heartbeat—it is sometimes used for things like performance anxiety or stage fright (Srinivasan, 2019).

Can propranolol help depression?

The relationship between propranolol and depression is a subject of controversy. Numerous case reports suggest that propranolol can cause depression, but two small prospective trials have failed to confirm this. The contemporary psychiatric literature is divided as to whether propranolol can cause depression.

What's another name for propranolol?

The extended-release propranolol capsule (brand name: Inderal LA) usually is taken once a day. The extended-release capsule (Innopran XL, Inderal XL) is usually taken at bedtime and should consistently be taken either always with or always without food each time.

Will doctors prescribe propranolol for anxiety?

Although propranolol is not FDA-approved to treat mental health disorders, some physicians will prescribe it off-label to treat anxiety patients.

Does propranolol help with social anxiety?

Propranolol (Inderal) Used for short-term relief of social anxiety. May reduce some peripheral symptoms of anxiety, such as tachycardia and sweating, and general tension, can help control symptoms of stage fright and public-speaking fears, has few side effects.

What is the difference between propranolol and diazepam?

Though diazepam was in general more effective than propranolol or placebo in relieving anxiety, propranolol was more effective than placebo in patients with somatic anxiety but not in those with psychic anxiety. We suggest that propranolol should be reserved for patients whose anxiety symptoms are mainly somatic.

Can propranolol affect your memory?

Yes, it’s possible that propranolol may affect your memory. Central nervous system (CNS) side effects of propranolol include short-term memory loss...

Does propranolol lower blood pressure?

Yes, propranolol lowers blood pressure. In fact, it is prescribed to treat high blood pressure. Propranolol is a type of drug called a beta blocker...

Does propranolol help with anxiety?

Propranolol is not approved by the U.S Food and Drug Administration (FDA) for use in patients with anxiety. Propranolol has been studied for anxiet...

How long does propranolol last?

How long propranolol effects last depends on many factors, such as what dosage you take and how your body processes medicines. One study in Clinica...

Does propranolol cause weight gain?

Yes, there is some evidence that propranolol can cause weight gain. It is not well known how much weight a person taking propranolol can expect to...

How long does propranolol take to work?

The peak effect of propranolol immediate-acting solution and propranolol tablets occurs about 1 to 4 hours after it is given. The peak effect of pr...

What's the maximum dose of propranolol?

The maximum dosage for propranolol depends on which dosage and form of the drug is prescribed and what condition is being treated.

What is the difference between propranolol and beta blockers?

Beta-blockers affect the heart and circulation. Propranolol is used to treat tremors, angina (chest pain), hypertension (high blood pressure), heart rhythm disorders, and other heart or circulatory conditions.

Can you take propranolol if you have asthma?

You should not use propranolol if you have asthma, very slow heart beats, or a serious heart condition such as "sick sinus syndrome" or "AV block" (unless you have a pacemaker).

Is propranolol good for anxiety?

Propranolol for Anxiety and Overcoming Anxiety - Anxiety and Depression - Propranolol. There is Help. Anxiety disorders affect 18% of the population in the U.S.

What is propranolol used for?

2. Upsides. May be used to treat high blood pressure (hypertension), either alone or in combination with thiazide diuretics or other medicines for hypertension.

How does propranolol work?

Propranolol is a medicine that may be used to treat certain heart conditions, reduce essential tremor, or prevent migraine. It works by blocking beta-receptors. There are two types of beta receptors, beta-1 receptors (located in the heart) and beta-2 receptors (located in the bronchioles of the lungs and the arteries of skeletal muscle).

What medications interact with propranolol?

Common medications that may interact with propranolol include: Some heart medications, such as amiodarone, clonidine, digoxin, diltiazem, propafenone, quinidine, and verapamil. NSAIDs, such as diclofenac, ibuprofen, and indomethacin, may decrease the blood pressure-lowering capabilities of propranolol.

What are some heart medications?

Some heart medications, such as amiodarone, clonidine, digoxin, diltiazem, propafenone, quinidine, and verapamil. Other medications including celecoxib, hydralazine, and rifampicin. NSAIDs, such as diclofenac, ibuprofen, and indomethacin, may decrease the blood pressure-lowering capabilities of propranolol.

Can propranolol cause dreams?

Propranolol is more likely than some other beta-blockers (such as atenolol) to cause vivid or unusual dreams. Abrupt discontinuation has been associated with exacerbation of angina, and rarely, heart attacks. Only discontinue on a doctor's advice and reduce dosage gradually over a few weeks.

Does propranolol help with tremors?

Experts are not sure how propranolol works to prevent migraines or tremors.

Does propranolol lower blood pressure?

Propranolol blocks beta-1 receptors in the heart which slows the heart rate and decreases how hard the heart has to work to pump blood around the body, decreasing blood pressure. Propranolol has a "nonselective" action.

Is propranolol a beta blocker?

Propranolol is a chemical compound which is widely used in the treatment of high blood pressure. This medication can be classified as a beta blocker. Propranolol can also be used to treat thyrotoxicosis, irregular heart rate (cardiac arrhythmia), stage fright, capillary hemangiomas, and benign tremors. Another important application of propranolol is in the prevention of migraines. Some important uses of propranolol are provided in this article.

Is propranolol addictive?

The advantage of using propranolol for the treatment of such anxiety disorders is that the side effects are fewer. Another notable advantage is that this drug is not addictive.

How does propranolol work?

Beta blockers, like propranolol, work by blocking beta receptors in your body which can blunt the effect of the hormone adrenaline and prevent the physical manifestation of anxiety symptoms including rapid hear beat, shaky hands, tremors, sweaty palms, mind blanking, and more. SSRI’s on the other hand regulate the amount of serotonin in your brain and prevent rapid mood changes and feelings of depression and anxiety.

When was propranolol first used?

Propranolol was first discovered and patented in 1962 by British scientist James W Black who later received a Nobel Prize for this historical discovery in 1988. Shortly after its discovery in 1965 its anti-anxiety effects were noted in a study related to the ability of propranolol to to reduce tachycardia (rapid heart rate). This sparked great interest in the drug from the psychiatric community who experimented with using propranolol for high trait anxiety in 1969, substance abuse disorder (heroin) in 1972, schizophrenia in 1974, autism in 1987, and aggressive behavior in 2006 with varying degrees of success, conclusiveness, and test population sample sizes.

What is the best medication for short term anxiety?

Propranolol is Best Used to Treat Short Term Event Driven Anxiety Issues. Often times benzos are prescribed for treatment of long term generalized anxiety disorders on an ongoing basis, beta blockers like propranolol are used to treat short term situational anxiety on a temporary or as needed basis.

How long does propranolol last?

Propranolol has a half life of 8 to 10 hours, however the effects of the drug (duration of action) is slightly longer at around 12 hours. This time window gives an adequate time frame to suppress symptoms of anxiety during most stressful situations.

What is the best medicine for anxiety?

Benzodiazepines such as Xanax and Valium are commonly prescribed to treat various forms of anxiety and phobias. At first glance beta blockers may seem similar to these benzo medications however they actually differ significantly in the following ways:

Is propranolol FDA approved?

Propranolol is not FDA approved for the treatment of anxiety, however it has been safely prescribed for the treatment of performance anxiety for decades as an “off label” use at the sole discretion of a licensed physician. Experience intense anxiety, shakes, and sweating before engaging in a high stress task like public speaking, taking an exam, ...

How long does propranolol last?

Suzman noted that since 1964, a total of 725 individuals exhibited anxiety disorders and of the 725, a total of 513 were treated with propranolol for time spans ranging from a few days to over 10 years.

Does propranolol lower blood pressure?

Users are likely to notice decreased blood pressure and a significant reduction in physical symptoms of anxiety. 5-HT receptors: Research suggests that propranolol may exhibit a modest affinity for 5-HT receptors.

Does propranolol block beta receptors?

Beta-1 and Beta-2 receptor blocking : Propra nolol exerts an anxiolytic effect principally by acting as a nonselective beta blocker. When administered, propranolol binds to beta-1 and beta-2 adrenergic receptors and inhibits activity at the respective receptor sites. Beta adrenoceptors commonly bind to stimulatory neurotransmitters such as epinephrine and norepinephrine, leading to enhanced sympathetic activation and cardiac stimulation.

Does propranolol affect serotonin?

In addition, there is some evidence to suggest that propranolol may act upon serotonin (5-HT ) receptor sites such as: 5-HT1B, 5-HT1A, and 5-HT2. Therefore, it may be necessary to consider that its ability to modulate serotonergic transmission may contribute to its anxiolytic effect.

Is propranolol an antihypertensive?

In addition to its efficacy as an antihypertensive, propranolol is commonly dispensed by medical professionals as a treatment for conditions including: dysrhythmias, hyperthyroidism, kinetic tremors, and migraine headaches.

Is propranolol a good first line anxiolytic?

However, due to limitations associated with the research, it is difficult to elucidate whether propranolol would be an effective first-line anxiolytic. The most comprehensive review of evidence and meta-analysis was published in 2015 and noted that there is insufficient evidence to recommend propranolol as a treatment for anxiety.

Is propranolol a placebo?

The study author noted that single-blinded, placebo-controlled trials noted the efficacy of beta-blockers for the treatment of anxiety. In conclusion, the author suggests propranolol is an effective intervention for the treatment of both somatic and psychological anxiety.

What is phentolamine in critical care?

A nurse is caring for a client in the critical care unit. Phentolamine (Regitine, OraVerse) has been ordered for the management of tissue necrosis caused by extravasation of parenterally administered drugs. Before administering this drug, the nurse will check the client's chart for indications of: diabetes mellitus.

What should a nurse do to help a client with high blood pressure?

What should the nurse do? Continue to take the client's blood pressure using different BP machines until a better blood pressure is obtained. Call the provider and advise them of the client's blood pressure prior to administering the medication. Give the medication so that the blood pressure will increase.

Why does a client stop taking medications?

While obtaining the clients history, the nurse learns the client stopped taking medications because the prescriptions ran out and had no funds to refill them.

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How It Works

  1. Propranolol is a medicine that may be used to treat certain heart conditions, reduce essential tremor, or prevent migraine. It works by blocking beta-receptors. There are two types of beta receptor...
  2. Propranolol blocks beta-1 receptors in the heart which slows the heart rate and decreases how hard the heart has to work to pump blood around the body, decreasing blood pressure.
  1. Propranolol is a medicine that may be used to treat certain heart conditions, reduce essential tremor, or prevent migraine. It works by blocking beta-receptors. There are two types of beta receptor...
  2. Propranolol blocks beta-1 receptors in the heart which slows the heart rate and decreases how hard the heart has to work to pump blood around the body, decreasing blood pressure.
  3. Propranolol has a "nonselective" action. This means that it also blocks beta-2 receptors in the bronchioles, which can cause a narrowing of the bronchioles which may cause breathing difficulties in...
  4. Propranolol also has a membrane-stabilizing effect at higher dosages which can affect the electrical impulses of the heart, although is not thought to contribute much to its antiarrhyth…

Upsides

  1. May be used to treat high blood pressure (hypertension), either alone or in combination with thiazide diuretics or other medicines for hypertension.
  2. May improve the symptoms of angina and increase a person with angina's capacity to exercise.
  3. May be used in the prevention of migraine headaches.
  1. May be used to treat high blood pressure (hypertension), either alone or in combination with thiazide diuretics or other medicines for hypertension.
  2. May improve the symptoms of angina and increase a person with angina's capacity to exercise.
  3. May be used in the prevention of migraine headaches.
  4. May improve symptoms of hypertrophic subaortic stenosis; however, will not change the course of the disease.

Downsides

  • If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: 1. Low blood pressure (which may be felt as dizziness upon standing); cold extremities or Raynaud's phenomenon (characterized by numbness and cold in the fingers and toes in response to cold temperatures o…
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Bottom Line

  • Propranolol is mainly used for blood pressure and angina control; however, it also has a role in migraine prevention and the treatment of essential tremor. Propranolol may cause vivid dreams and is not usually recommended for people with pre-existing breathing difficulties.
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Tips

  1. May be taken with or without food. Take exactly as directed. Do not increase or decrease the dosage without your doctor's advice.
  2. Swallow extended-release capsules whole: do not prise apart or chew.
  3. Should always be used as part of a comprehensive cardiovascular risk reduction program that includes diabetes management, smoking cessation, exercise, and other drug therapies. May …
  1. May be taken with or without food. Take exactly as directed. Do not increase or decrease the dosage without your doctor's advice.
  2. Swallow extended-release capsules whole: do not prise apart or chew.
  3. Should always be used as part of a comprehensive cardiovascular risk reduction program that includes diabetes management, smoking cessation, exercise, and other drug therapies. May be used in addit...
  4. Seek immediate medical advice if you find it difficult to breathe.

Response and Effectiveness

  1. Peak concentrations are reached within six hours following administration of extended-release (ER) capsules; effects last for 24 hours following ER dosing so ER capsules may be given once daily.
  2. Propranolol is lipophilic and can cross the blood/brain barrier (a semipermeable membrane that separates blood from the fluid surrounding the brain). This means it is more likely than s…
  1. Peak concentrations are reached within six hours following administration of extended-release (ER) capsules; effects last for 24 hours following ER dosing so ER capsules may be given once daily.
  2. Propranolol is lipophilic and can cross the blood/brain barrier (a semipermeable membrane that separates blood from the fluid surrounding the brain). This means it is more likely than some water-so...
  3. When used for essential tremor, there is a wide variation in individual response, and effective dosages may range from 60mg to 320mg. May be used daily or as needed before or during social situatio...

Interactions

  • Medicines that interact with propranolol may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with propranolol. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions sh…
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Further Information

  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use propranolol only for the indication prescribed. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Copyright 1996-2022 Drugs.com. Revision date: November 3, 2021. Medical Dis…
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