Precautions
Why is morning the best time to take pantoprazole?
- Prolonged Fasting. When you wake up, you already have at least 6-8 hours of fasting (during your sleep). ...
- More activation of pantoprazole (more acid in the morning). As we explained before, more fasting leads to more acid inside your stomach. ...
- More acid inhibition (more H-K-ATPase enzyme in the morning). ...
- More control over the post-meal acid secretion.
When should you take pantoprazole?
Tips
- Usually taken once daily.
- Swallow tablets whole; do not split, crush, or chew. ...
- Delayed-release granules should be sprinkled on one teaspoonful of apple sauce or apple juice and then swallowed whole. ...
- Take pantoprazole exactly as directed. ...
How long should I take pantoprazole?
With doses above 80 mg daily, the dose should be divided and given twice daily. Furthermore, how much pantoprazole can you take daily? Adults—40 milligrams (mg) once a day for up to 8 weeks. Your doctor may want you to take pantoprazole for more than 8 weeks for certain conditions.
How much pantoprazole can you take in a day?
- You can supplement with a good digestive enzyme formula to reduce the need for stomach acid.
- Take a teaspoon of apple cider vinegar mixed with water and a little honey at each meal.
- Drink less with your meals. Fluids dilute stomach acid, which triggers the stomach to produce more to compensate.
- Eat less at one time. ...
What are the alternatives to pantoprazole?
Who needs pantoprazole?
Pantoprazole is used to treat damage from gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus (the tube between the throat and stomach) in adults and children 5 years of age and older.
What are side effects of pantoprazole?
Pantoprazole side effectsheadache.diarrhea.stomach pain.nausea or vomiting.gas.dizziness.joint pain.
Is pantoprazole a painkiller?
No, Pantoprazole is not a pain killer. It is a proton pump inhibitor (PPI) used to treat conditions like gastroesophageal reflux disease (GERD) and erosive gastritis. The pain caused during these conditions can be treated with Pantoprazole by reducing gastric acid secretion.
What is the health benefit of pantoprazole?
This medication relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. It helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Pantoprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).
What medications should not be taken with pantoprazole?
Do not use pantoprazole together with medicines containing rilpivirine (eg, Complera®, Edurant®, Odefsey®).
Can pantoprazole cause sleep problems?
What Are Side Effects of Protonix? sleep problems (insomnia).
Is it better to take pantoprazole in the morning or at night?
Available in capsule and powder form, the 40-mg dose given at bedtime has been shown to be superior to pantoprazole 40 mg given at dinner in control of overnight pH.
Does pantoprazole affect blood pressure?
Omeprazole, lansoprazole and pantoprazole had no effect on blood pressure and electrocardiogram of anesthetized rat. Pharmacol Res.
How long does it take for pantoprazole to kick in?
You should start to feel better within 2 to 3 days. It may take up to 4 weeks for pantoprazole to work properly. You may still have symptoms during this time.
Does pantoprazole reduce inflammation?
Our data suggest that pantoprazole may have some anti-inflammatory effects on patients.
Can acid reflux make you feel weak and shaky?
Shock-like symptoms, including sudden weakness, dizziness, fainting or confusion demand that you go to the emergency room immediately. Barring other causes, your symptoms may stem from severe acid reflux.
Will pantoprazole help with gas?
For more information about bloating, see the section below. Pantoprazole is used to treat gastroesophageal reflux disease (GERD) and other conditions caused by your body making too much stomach acid. With GERD, you may have nausea and trouble swallowing. This can lead to loss of appetite, which may cause weight loss.
When should you take pantoprazole?
Take pantoprazole tablets immediately before a meal, preferably in the morning. Pantoprazole tablets may be taken with food or on an empty stomach....
Can pantoprazole cause anxiety?
Pantoprazole may cause side effects, but it does not seem to cause anxiety. Some people in clinical trials reported headaches while taking pantopra...
How long does pantoprazole take to work?
Pantoprazole starts to work within 2 and a half (2.5) hours – this is the time it takes for it to block the secretion of acid in the stomach - and...
Pantoprazole vs. omeprazole: What's the difference between them?
Pantoprazole and omeprazole are both medicines from the class of medications called proton pump inhibitors (PPIs). The approved uses for pantoprazo...
Can you take pantoprazole 40 mg twice a day?
The usual dosage for pantoprazole 40mg is 40mg once a day if you are buying it without a prescription or a physician's evaluation of your symptoms....
How long can I take pantoprazole?
You should only take pantoprazole for up to 8 weeks if you are buying it without a prescription or a physician evaluation of your symptoms. This is...
Does pantoprazole cause bloating?
Bloating has been reported as a side effect of regular pantoprazole use. One study reported bloating in 43% of patients taking a similar proton pum...
What is pantoprazole used for?
Pantoprazole is an acid-suppressing agent that may be used to treat conditions associated with excessive stomach acid production, such as gastroesophageal reflux (GERD), stomach ulcers, erosive esophagitis, and Zollinger-Ellison syndrome.
How does pantoprazole work?
Pantoprazole works by irreversibly blocking the actions of an enzyme responsible for acid production, called H+/K+ ATPase (also known as the gastric proton pump). The proton pump is located in the parietal cells of the stomach wall. Both baseline gastric acid secretion and stimulated gastric acid secretion are decreased in a dose-related manner (higher dosages cause a more pronounced decrease in stomach acid). Decreasing the production of stomach acid allows damaged tissue in the esophagus, stomach, and duodenum to heal.
How to make Protonix?
The mixture is stable for 62 days refrigerated. Removing the Protonix imprint from the tablets by rubbing with a paper towel impregnated with ethanol before crush ing them improves the look of the product.
How long does pantoprazole last?
The time to peak is 0.34 hours for the IV and 2.54 hours for the oral. Pantoprazole lasts for 24 hours (oral and IV).
How long can you take pantoprazole?
Pantoprazole is normally taken short term (up to 8 weeks), unless it is being used for hypersecretory conditions such as Zollinger-Ellison syndrome in adults. Talk to your doctor about how long you need to stay on pantoprazole for.
What class is pantoprazole?
Pantoprazole belongs to the class of medicines known as proton pump inhibitors (PPIs).
Can pantoprazole interfere with lab tests?
May also interfere with some laboratory tests. May mask the symptoms of gastric cancer. An endoscopy may be necessary for some people (especially seniors) before pantoprazole treatment to rule out malignancy, or for those who don't respond to treatment or relapse soon after pantoprazole is discontinued.
What is the purpose of pantoprazole?
Pantoprazole is used to treat certain stomach and esophagus problems (such as acid reflux ). It works by decreasing the amount of acid your stomach makes. This medication relieves symptoms such as heartburn, difficulty swallowing, and persistent cough.
How to report pantoprazole side effects in Canada?
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Before taking pantoprazole, tell your doctor or pharmacist if you are allergic to it; or to similar drugs (such as lansoprazole, omeprazole ); or if you have any other allergies.
Where do you give granules?
If you are giving the granules through a tube into the stomach (nasogastric or gastric tube), ask your health care professional for detailed instructions on how to properly mix and give it.
Does pantoprazole cause bone fractures?
Proton pump inhibitors (such as pantoprazole) may increase your risk for bone fractures, especially with longer use, higher doses, and in older adults. Talk with your doctor or pharmacist about ways to prevent bone loss /fracture, such as by taking calcium (such as calcium citrate) and vitamin D supplements.
Does Pantoprazole affect stomach acid?
Some products need stomach acid so that the body can absorb them properly. Pantoprazole decreases stomach acid, so it may change how well these products work. Some affected products include ampicillin, atazanavir, erlotinib, nelfinavir, pazopanib, rilpivirine, certain azole antifungals ( itraconazole, ketoconazole, posaconazole), among others.
What is Pantoprazole used for?
Pantoprazole oral tablet is used to reduce the amount of stomach acid your body makes. It helps treat painful symptoms caused by conditions such as gastroesophageal reflux disease (GERD). With GERD, gastric juices flow upward from your stomach and into the esophagus.
What is the name of the pill that is injected into the vein?
Brand-name: Protonix. Pantoprazole comes in three forms: an oral tablet, an oral liquida suspension, and an intravenous (IV) form that’s injected into your vein by a healthcare provider. Pantoprazole oral tablet is used to reduce the amount of stomach acid your body makes.
Can pantoprazole cause cutaneous lupus?
Cutaneous lupus erythematosus and systemic lupus erythematosus warning: Pantoprazole can cause cutaneous lupus erythematosus (CLE) and systemic lupus erythematosus (SLE). CLE and SLE are autoimmune diseases. Symptoms of CLE can range from a rash on the skin and nose, to a raised, scaly, red or purple rash on certain parts of the body.
Does pantoprazole affect stomach acid?
Pantoprazole affects stomach acid levels. As a result, it can reduce your body’s absorption of certain drugs that are sensitive to the effects of decreased stomach acid. This effect can make these drugs less effective. Examples of these drugs include: ketoconazole.
Can you take pantoprazole with HIV?
Taking certain HIV drugs with pantoprazole is not recommended. Pantoprazole may significantly decrease the amount of these drugs in your body. This can reduce their ability to control HIV infection. These drugs are:
Does pantoprazole cause bone fracture?
Long-term use warning: Long-term use of pantoprazole can lead to an increased risk of certain side effects and complications. These include: Increased risk of bone fracture in people taking higher, multiple daily doses for more than one year. Vitamin B-12 deficiency, which can lead to serious nerve damage and deteriorating brain functions.
Can pantoprazole interact with other medications?
Pantoprazole oral tablet can interact with other medications, herbs, or vitamins you might be taking. That’s why your doctor should manage all of your medications carefully. If you’re curious about how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.
Why is pantoprazole prescribed?
Why is this medication prescribed? Expand Section. Pantoprazole is used to treat damage from gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus (the tube between the throat and stomach) in adults and children 5 years of age and older.
How should this medicine be used?
Pantoprazole comes as a delayed-release (releases the medication in the intestine to prevent break-down of the medication by stomach acids) tablet and as delayed-release granules to take by mouth . The packets of delayed-release granules must be mixed with applesauce or apple juice and taken by mouth or given through a feeding tube. For the treatment and maintenance of GERD, pantoprazole is usually taken once a day. For the treatment of conditions where the stomach produces too much acid, pantoprazole is usually taken twice a day. The delayed-release tablets are usually taken with or without food, and the granules are usually taken 30 minutes before a meal. Take pantoprazole at around the same time (s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take pantoprazole exactly as directed. Do not take more or less of it or take it more often or for a longer period of time than prescribed by your doctor.
What should I know about storage and disposal of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
Can you take more or less pantoprazole?
Take pantoprazole exactly as directed. Do not take more or less of it or take it more often or for a longer period of time than prescribed by your doctor.
Can you swallow 40 mg of a tablet?
Swallow the tablets whole; do not split, chew, or crush them. If your doctor has prescribed the 40 mg tablet and it is too big for you to swallow, ask your doctor to prescribe two of the 20 mg tablets instead.
Can you take pantoprazole through a tube?
Pantoprazole granules mixed with apple juice may be given through a feeding tube. If you have a feeding tube, ask your doctor how you should take pantoprazole.
What is pantoprazole oral tablet?
If you have problems with your esophagus or stomach, your doctor may prescribe pantoprazole for you.
What are the side effects of pantoprazole?
Mild side effects of pantoprazole oral tablets that have been reported include: belly pain. diarrhea.
What are pantoprazole oral tablet’s side effects?
Like most drugs, pantoprazole oral tablets may cause mild or serious side effects . The lists below describe some of the more common side effects that pantoprazole may cause. These lists don’t include all possible side effects.
What should be done in case of overdose?
Don’t take more pantoprazole oral tablets than your doctor prescribes. Using more than this can lead to serious side effects.
What is the name of the drug that is used to treat similar conditions?
Both pantoprazole and esomeprazole (Nexium) belong to a group of drugs called proton pump inhibitors (PPIs). Both drugs are used to treat similar conditions.
What is the name of the drug that is a proton pump inhibitor?
Pantoprazole belongs to a group of drugs called proton pump inhibitors (PPIs).
What are the interactions with pantoprazole?
Interactions. Taking medications, vaccines, foods, and other things with a certain drug can affect how the drug works. These effects are called interactions. Before taking pantoprazole oral tablets, be sure to tell your doctor about all medications you take, including prescription and over-the-counter types.
What is pantoprazole (Protonix)? How does it work (mechanism of action)?
Pantoprazole is in a class of drugs called proton pump inhibitors ( PPIs ), which block the production of acid by the stomach. Other drugs in the same class include lansoprazole ( Prevacid ), omeprazole ( Prilosec) and rabeprazole ( Aciphex ). Proton pump inhibitors are used for the treatment of stomach conditions such as duodenal and peptic ulcers, gastroesophageal reflux disease ( GERD ), and Zollinger-Ellison syndrome that are caused by stomach acid.
When was Pantoprazole approved?
By blocking the enzyme, the production of acid is decreased, and this allows the stomach and esophagus to heal. The FDA approved Pantoprazole in February 2000.
What is the dosage for Protonix?
Pantoprazole used for treatment GERD and healing erosive esophagitis the recommended dose for adults is 40 mg daily for 4-8 weeks.
What is the name of the drug that is used to treat GERD?
Pantoprazole, brand name Protonix, is a drug that belongs to the class of drugs called proton pump inhibitors (PPIs). Protonix is used for the treatment of GERD (gastroesophageal reflux disease), stomach (peptic) and duodenum ulcers, and Zollinger-Ellison syndrome. Side effects of Protonix include phototoxicity (sensitivity to light) dizziness, ...
What are the effects of proton pump inhibitors?
Proton pump inhibitors reduce blood levels of atazanavir ( Reyataz) or nelfinavir ( Viracept ), reducing their effect. Proton pump inhibitors may also increase the action of warfarin ( Coumadin. Jantoven ), increasing the risk of bleeding.
Is pantoprazole tolerated?
Pantoprazole like other PPIs is well tolerated. The most common side effects are:
Does Protonix cause rhabdomyolysis?
Serious side effects of Protonix are live damage, rhabdomyolysis ( muscle breakdown), pancreatitis, and reduces levels of blood cells. Adverse effects and risks of Protonix used in high doses and long-term (one year or longer) include osteoporosis, C. diff infection, low levels of magnesium, and heart attacks.
What is Pantoprazole used for?
Descriptions. Pantoprazole is used to treat certain conditions in which there is too much acid in the stomach. It is used to treat erosive esophagitis or "heartburn" caused by gastroesophageal reflux disease (GERD), a condition where the acid in the stomach washes back up into the esophagus. This medicine may also be used to treat Zollinger-Ellison ...
How does pantoprazole work?
Pantoprazole is a proton pump inhibitor (PPI). It works by decreasing the amount of acid produced by the stomach.
How It Works
Pantoprazole is used to treat certain stomach and esophagus problems (such as acid reflux).
May Treat: Gastroesophageal reflux disease · Erosive esophagitis · Zollinger-Ellison syndrome · Acute gastric ulcer with hemorrhage · Gastric hypersecretion with systemic mastocytosis and more
Brand Names: Protonix
Drug Class: Gastric Acid Secretion Reducer - Proton Pump Inhibitors (PPIs)
Availability: Prescription Required
Pregnancy: Consult a doctor before using
Lactation: Consult a doctor before using
- Call doctor if you are not getting better
- Call doctor if you are not getting better
- Call MD now for heartburn with sweating & dizziness
- Call doctor if you get severe diarrhea
- For granules delayed release for susp packet products : Wash down as directed. DO NOT chew granules.
- For tablet, delayed release products : Before use, important to read the Medication Guide. Call MD or RPh re. timing of taking with other meds. Swallow whole. Do not break/chew/crush/dissolve. Success is dependent on completing therapy course. May increase risk of bone fractures.
- For vial products : For intravenous injection dilute prior to use. Prepare carefully as you have been shown. Take at the same time(s) daily as directed. Recommended for short term use only. Tell doctor your complete medical history.
Upsides
Downsides
Bottom Line
Tips
- Pantoprazole is an acid-suppressing agent that may be used to treat conditions associated with excessive stomach acid production, such as gastroesophageal reflux (GERD), stomach ulcers, erosive eso...
- Pantoprazole works by irreversibly blocking the actions of an enzyme responsible for acid production, called H+/K+ ATPase (also known as the gastric proton pump). The proton pum…
- Pantoprazole is an acid-suppressing agent that may be used to treat conditions associated with excessive stomach acid production, such as gastroesophageal reflux (GERD), stomach ulcers, erosive eso...
- Pantoprazole works by irreversibly blocking the actions of an enzyme responsible for acid production, called H+/K+ ATPase (also known as the gastric proton pump). The proton pump is located in the...
- Pantoprazole belongs to the class of medicines known as proton pump inhibitors (PPIs).
Response and Effectiveness
- Oral pantoprazole may be used for the short-term treatment of erosive or nonerosive gastroesophageal reflux disease (GERD) in adults and children over the age of 5 years. May also be used for the m...
- Both oral and IV pantoprazole may be useful for the treatment of hypersecretory conditions such as Zollinger-Ellison syndrome in adults.
- Oral pantoprazole may be used for the short-term treatment of erosive or nonerosive gastroesophageal reflux disease (GERD) in adults and children over the age of 5 years. May also be used for the m...
- Both oral and IV pantoprazole may be useful for the treatment of hypersecretory conditions such as Zollinger-Ellison syndrome in adults.
- IV pantoprazole may be used short-term to treat gastroesophageal reflux disease associated with a history of erosive esophagitis.
- May be used off-label for aspiration prophylaxis in patients undergoing anesthesia, for Barrett's esophagus, for functional dyspepsia, for helicobacter pylori eradication, for primary prevention of...
Interactions
- If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: 1. A headache, dizziness, nausea or vomiting, abdominal pain, diarrhea, joint pain, and flatulence. 2. May also interfere with some laboratory tests. 3. May mask the symptoms of gastric cancer. An endoscopy may be nec…
Further Information
- Pantoprazole is a proton pump inhibitor that decreases acid secretion in the stomach and may be given to relieve the symptoms of heartburn or to allow inflamed tissue in the gastrointestinal tract to heal. Pantoprazole tablets are delayed-release and should not be split, crushed, or chewed; pantoprazole oral granules are available.