Opioid treatment is contraindicated in a patient who has obstructive sleep apnea, because the patient may experience respiratory depression. Opioid analgesics may be safely used in a patient who has breast cancer, psychological illness, or rheumatoid arthritis.
Full Answer
What are the absolute contraindications to opioid prescribing?
The use of a pure agonist with a weak partial agonist is contraindicated because when a weak partial agonist such as pentazocine is given to a patient also receiving a full agonist (eg, morphine), there is a risk of diminishing analgesia or even inducing a state of withdrawal; combining full agonist with partial agonist opioids should be avoided.
Why is the use of opioids contraindicated in patients with elevated intracranial pressure?
Treatment of opioid overdose. Opioid overdose is usually treated with opioid receptor antagonists such as naloxone (Narcan) • Naloxone competes for the same receptors as opioid drugs, but blocks them rather than activating them. • The FDA recently approved naloxone as a nasal spray without the need for a prescription.
Why is the use of opioids contraindicated in pregnant women?
One of the most severe adverse reactions to opiate treatment is respiratory depression. Specific antagonists have been developed to reverse the respiratory depression associated with the opioid. ... Opioid antagonists contraindications. ... Use cautiously in pregnancy, opioid-dependent mothers, and in patients with an opioid dependency, or ...
When are opioids used intraoperatively in general anesthetics?
Opiate use is contraindicated in patients with known hypersensitivity to the drugs. These drugs are contraindicated in patients with acute bronchial asthma and emphysema or upper airway obstruction and in patients with head injury or increased intracranial pressure.
What are the contraindications for opioids?
Opioid therapy trial should NOT be initiated if any of the following absolute contraindications are evident:Severe respiratory instability.Acute psychiatric instability or uncontrolled suicide risk.Diagnosed substance use disorder not in remission or under treatment.True allergy to opioids.More items...
Which condition listed in the patients medical history could be a contraindication to administration of morphine?
4 CONTRAINDICATIONS Morphine sulfate is contraindicated in patients with acute or severe bronchial asthma or hypercarbia. Morphine sulfate is contraindicated in any patient who has or is suspected of having paralytic ileus.
What other indications can opioids be used for?
Opioids are used primarily for their strong analgesic effect, but may also be used for other indications such as for their anti-diarrheal and cough-suppressant effects. Adverse effects related to opioids include sedation/drowsiness, respiratory depression, nausea/vomiting and constipation.
What are contraindications of analgesics?
Who should not take ASPIRIN EC?systemic mastocytosis.low vitamin K levels.a type of joint disorder due to excess uric acid in the blood called gout.anemia.hemophilia.a decrease in the blood clotting protein prothrombin.blood clotting disorder - von Willebrand's disease.decreased blood platelets.More items...
Which condition is a contraindication for barbiturates?
Barbiturates should be administered with caution, if at all, to patients who are mentally depressed, have suicidal tendencies, or a history of drug abuse.
Which conditions are contraindications for therapy with pyridostigmine?
Contraindications / PrecautionsGeneral Information. ... Bromide hypersensitivity. ... Bladder obstruction, GI obstruction, ileus, urinary tract obstruction. ... Cholinesterase inhibitor toxicity. ... Asthma, bradycardia, cardiac arrhythmias, chronic obstructive pulmonary disease (COPD), glaucoma, hypertension. ... Neonates. ... Renal disease.More items...
When are opioids used for chronic pain?
Recommendations focus on the use of opioids in treating chronic pain (pain lasting longer than 3 months or past the time of normal tissue healing) outside of active cancer treatment, palliative care, and end-of-life care.
What are opioids examples?
Opioids are a class of drugs that include the illegal drug heroin, synthetic opioids such as fentanyl, and pain relievers available legally by prescription, such as oxycodone (OxyContin®), hydrocodone (Vicodin®), codeine, morphine, and many others.
What are the contraindications of acetaminophen?
Contraindications to the use of acetaminophen include hypersensitivity to acetaminophen, severe hepatic impairment, or severe active hepatic disease.
What is an opioid antagonist?
Opioid antagonist. has a greater affinity for a cell receptor than an opiate drug agonist. One of the most severe adverse reactions to opiate treatment is respiratory depression. Specific antagonists have been developed to reverse the respiratory depression associated with the opioid. Opioid antagonist action.
What is an opioid naive?
Opioid naive. No previous use or infrequent use of opioid medications. Opioid antagonist. has a greater affinity for a cell receptor than an opiate drug agonist. One of the most severe adverse reactions to opiate treatment is respiratory depression.
What is an antagonist?
Antagonist. Substance that counteracts the action of something else. Opioid naive. No previous use or infrequent use of opioid medications. Opioid antagonist. has a greater affinity for a cell receptor than an opiate drug agonist. One of the most severe adverse reactions to opiate treatment is respiratory depression.
What is a pregnancy category B?
Pregnancy category B. Opiate antagonist interactions. These drugs produce withdrawal symptoms in individuals who physically depend on the Opioid.. antagonist may prevent the action or intended use of opioid Antidiarrheals, antitussives, and analgesic.