What is high active antiretroviral therapy?
Highly active antiretroviral therapy (HAART) is a medication regimen used in the management and treatment of human immunodeficiency virus type 1 (HIV-1). It is composed of several drugs in the antiretroviral classes of medications.
What is the standard of care for treatment-naive patients with HIV-1?
Enhancing Healthcare Team Outcomes Currently, the standard of care for a treatment-naïve patient with HIV-1 is a three-drug, highly active antiretroviral therapy (HAART) regimen that is started as soon as possible after a patient tests positive for HIV.
Is adherence to highly active antiretroviral therapy required for successful treatment of HIV/AIDS?
Background: Adherence to highly active antiretroviral therapy (HAART) of 95% or greater seems to be required for successful treatment of HIV/AIDS.
Why are HAART regimens important in HIV treatment?
HAART regimens are essential to improve patient outcomes and reduce transmission of HIV, but medication management is a dynamic process that must be monitored by healthcare professionals. Proper utilization and adherence to a HAART regimen are essential to ensure a therapeutic response and prevent viral resistance.
Why does a 68 year old have a creatinine level of 2.3?
A 68 year old man has a serum creatinine of 2.3 mg/dL due to chronically increased hydrostatic pressure in Bowman space. Which of the following disorders is the most likely cause of these finding?
Why is heparin used in addition to warfarin?
I can't remember the exact answer but heparin is used in addition to beginning warfarin because of the half lives of coagulation factors II, VII, IX, X ... they have to be cleared from the system before an effect is seen since warfarin inhibits vit k epoxidase during the production of coagulation factors.
How does HAART help with HIV?
Improve immune function. Reducing the transmission of HIV-1 to others is a primary goal of HAART. With the use of HAART, a reduction of HIV-1 RNA levels has been shown to reduce the risk of sexual transmission to partners to nearly zero in some studies, even among couples that engaged in condomless sexual acts.
How many different types of HIV medications are there?
For the treatment of HIV, there are more than 25 different medications in six different classes, for which a detailed discussion will follow in further sections.
Why is a HAART regimen important?
HAART regimens are essential to improve patient outcomes and reduce transmission of HIV , but medication management is a dynamic process that must be monitored by healthcare professionals. Proper utilization and adherence to a HAART regimen are essential to ensure a therapeutic response and prevent viral resistance.
What medications should I avoid with hepatic dysfunction?
Patients with a history of hepatic dysfunction should avoid efavirenz, tenofovir-disoproxil fumarate (TDF), and maraviroc. Patients with a history of renal dysfunction should avoid or adjust dosages of tenofovir, maraviroc, and atazanavir.
What are some examples of integrase inhibitors?
Examples include: dolutegravir, elvitegravir, raltegravir. Fusion inhibitors (FIs) Fusion inhibitors bind to the envelope glycoprotein gp41 and prevent viral fusion to the CD4 T-cells.
Is Integrase inhibitor a good HAART?
Integrase Inhibitors (INSTIs)[39][40][41] INSTIs are generally well-tolerated, and in many cases, they are favorable as the third agent in a HAART regimen due to their neutral effects on cholesterol and triglyceride levels. Some patients may experience dizziness, sleep disturbances, or depression.
Does dolutegravir affect creatinine?
Dolutegravir can block the secretion of creatinine and occasionally cause a decrease in the GFR.[42] It can also interact with several medications, including those that inhibit/induce CYP3A4 enzymes, metformin, rifampin, and antiepileptics.