What is the role of metronidazole in the treatment of bacterial vaginosis?
Brandt M, Abels C, May T, Lohmann K, Schmidts-Winkler I, Hoyme UB. Intravaginally applied metronidazole is as effective as orally applied in the treatment of bacterial vaginosis, but exhibits significantly less side effects.
Should I Call my doctor if I take metronidazole vaginal?
Call your doctor if your symptoms do not improve, or if they get worse. Metronidazole vaginal will not treat a vaginal yeast infection. You may even develop a new vaginal yeast infection after using this medicine. Watch for symptoms such as itching or discharge during or after treatment with metronidazole vaginal.
What are the recommended regimens for the treatment of metronidazole toxicity?
Three recommended regimens Metronidazole 500 mg orally twice daily for 7 days Metronidazole gel 0.75%, 1 full application (5 g) intravaginally, once daily for 5 days Clindamycin cream 2%, 1 full application (5 g) intravaginally at bedtime for 7 days
What is the optimal route of administration for metronidazole vaginal gel?
Routes of administration Two randomized controlled studies directly compared the efficacy of vaginal (0.75% metronidazole vaginal gel 5 g, twice daily for 5 days) vs oral regimens (500 mg twice daily for 7 days).
What are nursing interventions for metronidazole?
InterventionsBLACK BOX WARNING: Avoid use unless necessary. Metronidazole may be carcinogenic.Administer oral doses with food.Apply topically (MetroGel) after cleansing the area. Advise patient that cosmetics may be used over the area after application.Reduce dosage in hepatic disease.
What advice should be given to a patient taking metronidazole?
Swallow metronidazole tablets with plenty of water. Take them with a meal or a snack. Do not drink alcohol while you are taking metronidazole, and for 48 hours after finishing your course of treatment. Space your doses evenly throughout the day, and keep taking the medicine until the course is finished.
What is the role of Flagyl in nursing?
We use this drug for intraabdominal infections for gynecologic infections, skin infections, bone and joint infections, central nervous system infections septicemia also for endocarditis am EIC liver disease and peptic ulcer disease.
When taking metronidazole Flagyl What do you need to instruct the patient to avoid?
While taking metronidazole and for 3 days after your last dose: Do not drink alcohol or consume foods, medicines, or other products that contain alcohol or propylene glycol. You may have unpleasant effects such as headaches, nausea, vomiting, stomach cramps, and warmth or tingling under your skin.
What should I avoid while taking Flagyl?
While taking metronidazole and for 3 days after your last dose: Do not drink alcohol or consume foods, medicines, or other products that contain alcohol or propylene glycol. You may have unpleasant effects such as headaches, nausea, vomiting, stomach cramps, and warmth or tingling under your skin.
How do you take metronidazole for BV?
Metronidazole — Metronidazole vaginal gel is one of the most effective treatments; it is applied inside the vagina at bedtime for five days. Metronidazole can also be taken in pill form, 500 mg twice daily for seven days. The choice of pill versus vaginal gel depends upon the woman's preference.
What are the nursing responsibilities for giving antibiotics?
In relation to antibiotics, nurses are recommended to be active in antibiotic stewardship that ensures proper management of antibiotics to minimize antibiotic resistance. Some of the roles of nurses include administering antibiotics, monitoring its effectiveness and educating the patient.
What is a nursing consideration?
Nursing consideration and implications are generally summed up as being what a nurse needs to know and do in a particular situation.
How do you use metronidazole?
Adults—One 500 milligram (mg) tablet, inserted high into the vagina. Use the medicine once a day in the evening for 10 or 20 days.Children—Use and dose must be determined by your doctor.
What are the most common side effects of metronidazole?
Metronidazole may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:vomiting.nausea.diarrhea.constipation.upset stomach.stomach cramps.loss of appetite.headache.More items...•
What are contraindications for metronidazole?
Who should not take METRONIDAZOLE?meningitis not due to an infection.low levels of a type of white blood cell called neutrophils.alcoholism.alcohol intoxication.a low seizure threshold.a painful condition that affects the nerves in the legs and arms called peripheral neuropathy.prolonged QT interval on EKG.seizures.More items...
How do you deal with the side effects of Flagyl?
Metronidazole may cause dry mouth, an unpleasant or sharp metallic taste, and a change in taste sensation. For temporary relief of dry mouth, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute.
What Is metronidazole vaginal?
Metronidazole is an antibiotic that fights bacteria in the body.Metronidazole vaginal (for use in the vagina) is used to treat vaginal infections c...
Before Taking This Medicine
You should not use this medicine if you are allergic to metronidazole, or if: 1. you are allergic to parabens or polyethylene glycol; 2. you recent...
How Should I Use metronidazole vaginal?
Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.Use this med...
What Happens If I Miss A Dose?
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to m...
What Happens If I Overdose?
An overdose of metronidazole vaginal is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-12...
What Should I Avoid While Using metronidazole vaginal?
While you are using this medicine and for 24 hours after your last dose: Avoid drinking alcohol or consuming foods or other products that contain a...
metronidazole Vaginal Side Effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.Ra...
metronidazole Vaginal Dosing Information
Usual Adult Dose for Acne Rosacea:1% Topical Cream or Gel: Apply and rub in a thin film to the affected area(s) once a day0.75% Topical Cream, Gel,...
What Other Drugs Will Affect metronidazole vaginal?
Tell your doctor about all your current medicines and any you start or stop using, especially: 1. lithium; or 2. a blood thinner (warfarin, Coumadi...
Diagnostic Considerations
BV can be diagnosed by using clinical criteria (i.e., Amsel’s diagnostic criteria) ( 999) or by determining the Nugent score from a vaginal Gram stain ( 1000 ).
Treatment
Treatment for BV is recommended for women with symptoms. Established benefits of therapy among nonpregnant women are to relieve vaginal symptoms and signs of infection. Other potential benefits of treatment include reduction in the risk for acquiring C. trachomatis, N. gonorrhoeae, T. vaginalis, M.
Follow-Up
Follow-up visits are unnecessary if symptoms resolve. Because persistent or recurrent BV is common, women should be advised to return for evaluation if symptoms recur. Limited data are available regarding optimal management strategies for women with persistent or recurrent BV.
Management of Sex Partners
Data from earlier clinical trials indicate that a woman’s response to therapy and the likelihood of relapse or recurrence are not affected by treatment of her sex partner ( 998 ). Therefore, routine treatment of sex partners is not recommended.
Special Considerations
Intravaginal clindamycin cream is preferred in case of allergy or intolerance to metronidazole or tinidazole. Intravaginal metronidazole gel can be considered for women who are not allergic to metronidazole but do not tolerate oral metronidazole.
What is the best treatment for bacterial vaginosis?
Treatment options include oral or vaginal metronidazole or clindamycin, all of which provide high cure rates. Vaginal antibiotics result in minimal risk to the fetus in pregnant patients. Conclusions: Complications of bacterial vaginosis may be associated with significant morbidity, especially among pregnant women.
What is the purpose of the article on bacterial vaginosis?
Objective: The purpose of this article is to review the treatment options for bacterial vaginosis, including the newer topical antibiotics, metronidazole gel and clindamycin cream. The article also examines the controversies over whether bacterial vaginosis is a sexually transmitted disease and whether asymptomatic women should be treated.
Is bacterial vaginosis a sexually transmitted disease?
Data synthesis: There is evidence both for and against bacterial vaginosis being a sexually transmitted disease. Potential complications of the disease may warrant treatment of certain asymptomatic women, especially during pregnancy. Treatment options include oral or vaginal metronidazole or clindamycin, all of which provide high cure rates.
Is clindamycin a good antibiotic for asymptomatic women?
Treatment of asymptomatic women with the disease is controversial, but may be justified in certain high-risk populations. The topical agents, clindamycin vaginal cream 2% and metronidazole vaginal gel 0.75% provide a safe, effective, but expensive alternative to oral antibiotic regimens for the treatment of bacterial vaginosis.
What is metronidazole used for?
Metronidazole is a nitroimidazole antimicrobial agent used to manage protozoal infections such as trichomoniasis and anaerobic infections.18 Since the early 1980s, metronidazole has been used widely in the treatment of BV with good clinical results.
What is the treatment for BV?
This lincosamide antibiotic, a subclass of the larger family of macrolide antibiotics, has various treatment preparations including vaginal (ovule and cream) and oral. Clindamycin vs placebo .
What is BV in women?
Bacterial vaginosis (BV) is a common cause of malodorous vaginal discharge in women of reproductive age.1Women’s awareness of BV is low and often they self-medicate with antifungals before presenting very late when symptoms have become intolerable.
Is tinidazole an antibiotic?
Tinidazole is a nitroimidazole antibiotic and an antiprotozoal agent that was first reported in Europe, Asia, and Latin America for its use in BV treatment. Trials evaluating oral regimens of 1–2 g daily for 1–5 days have given favorable results.30Tinidazole was licensed recently in the US for the treatment of BV.31.
Do probiotics help with BV?
Finally, several studies have evaluated the clinical and microbiological efficacy of probiotics to treat and to prevent the recurrence of BV. Despite the need for more clinical studies, probiotics should be considered as part of the approach to disease prevention, and as an adjunct to antimicrobial treatment.92.
Is eugenol a BV phenylpropene?
vaginalisbiofilms; and eugenol is a phenylpropene extracted in particular from clove oil.
Is secnidazole tolerated?
Secnidazole was well tolerated and adverse events were similar in both groups (38% in the metronidazole group and 39% in the secnidazole group). Although headaches were rarely reported, they were more frequent in the secnidazole group (9% vs 4%). Duration of oral regimens .
What should a nurse do when admitting a client with glaucoma?
The nurse should: 1. allow the client to keep the eyedrops at the bedside and use as prescribed on the bottle.
What is the priority for nursing care for an older adult who has pruritus, is continuously scratching the affected
A priority for nursing care for an older adult who has pruritus, is continuously scratching the affected areas, and demonstrates agitation and anxiety regarding the itching is: 1. preventing infection. 2. instructing the client not to scratch.