Treatment FAQ

methotrexate treatment for ectopic pregnancy what to expect

by Dale Prosacco Published 2 years ago Updated 2 years ago
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Treatment

  • Medication. An early ectopic pregnancy without unstable bleeding is most often treated with a medication called methotrexate, which stops cell growth and dissolves existing cells.
  • Laparoscopic procedures. Salpingostomy and salpingectomy are two laparoscopic surgeries used to treat some ectopic pregnancies.
  • Emergency surgery. ...

Methotrexate is given by injection. After treatment, you may have mild abdominal pain or cramping. Some women also have nausea and vomiting, diarrhea, or fatigue. There are some cases when you can't use methotrexate.

Full Answer

When to expect period after methotrexate for ectopic pregnancy?

You may want to check with your doctor before TTC right away, because some advise that you wait 3 months after treatment with methotrexate before conceiving. I was able to conceive after my EP, but it took about a year and a half to happen.

What are the surgery options for an ectopic pregnancy?

What Is Ectopic Pregnancy Surgery?

  • Surgical Approaches. With a laparotomy, a large incision is made in the skin of the abdomen to remove the pregnancy tissue.
  • Contraindications. Certain medical conditions, like underlying heart or lung disease, may increase a patient's risk for complications during surgery.
  • Potential Risks. ...

How to recognize and treat an ectopic pregnancy?

Treatment

  • Medication. An early ectopic pregnancy without unstable bleeding is most often treated with a medication called methotrexate, which stops cell growth and dissolves existing cells.
  • Laparoscopic procedures. Salpingostomy and salpingectomy are two laparoscopic surgeries used to treat some ectopic pregnancies.
  • Emergency surgery. ...

What are the risk factors for ectopic pregnancy?

  • Aged between 25 and 34 years old
  • History of pelvic inflammatory disease, such as chlamydia
  • Endometriosis
  • Previous abdominal surgery, such as removal of the appendix
  • IntraUterine Contraceptive Device (IUCD) (coil)
  • Taking the progesterone-only contraceptive pill (mini pill)
  • IVF treatment
  • Previous ectopic pregnancy
  • Smoking

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How long does it take for an ectopic pregnancy to dissolve after having methotrexate?

The average time of resolution for ectopic pregnancy was 32 days for single dose of methotrexate and 58 days for those receiving two doses or more.

What happens after you take methotrexate for ectopic pregnancy?

After you get methotrexate, you may have: mild to moderate cramps or pain in the abdomen. vaginal bleeding (like a period)

How do you feel after methotrexate injection?

Common side effects are:Feeling tired.Abdominal pain or cramping.Nausea and/or vomiting for 24 hours.Upset stomach, decreased appetite.Diarrhea.Sores in your mouth.Headache.Redness, swelling, or pain at the injection site.More items...

How long does it take to recover from ectopic pregnancy injection?

Most women can leave hospital a few days after surgery, although it can take 4 to 6 weeks to fully recover.

How soon after methotrexate will I start bleeding?

A few days after the injection, it is usual to begin to bleed and this bleeding can last between a few days and up to 6 weeks. It is usual to have some discomfort and pain initially but as long as this is not severe.

How fast do hCG levels drop after methotrexate?

hCG levels frequently increase between the day of administration and day 4; however, there should be a 15% or greater drop in hCG between days 4 and 7. If this does not occur, another dose of MTX is given.

Why should you not touch methotrexate?

Methotrexate and pregnancy Even touching or inhaling the dust from the tablet can allow the medicine to get into the body. Methotrexate goes into sperm, so it's important that a man taking it doesn't get his partner pregnant.

How do I know if methotrexate is working for ectopic pregnancy?

To see if the methotrexate has worked, you will need to return to the clinic to have a blood test 1 week after receiving it. You will need to repeat this test once a week until we can see that there is no more pregnancy hormone left in your body. When this happens, we know that the medication has worked.

Does methotrexate make you sleepy?

It is also used to treat many other diseases, and in much higher doses it can also be used to treat cancers of certain types. Even though MTX is effective in reducing pain and joint damage and improving joint function, patients taking MTX commonly report experiencing fatigue. And it isn't just a feeling of being tired.

Can your tube rupture after methotrexate?

There is still around a one in 14 chance of your fallopian tubes splitting open (rupture) after medical treatment with methotrexate, even if your hCG levels are going down. Therefore, be aware of the potential symptoms of a rupture and be ready to call an ambulance if you think a rupture has occurred.

How do I know if methotrexate is working?

When you first start treatment, you'll have a check-up and blood tests every 1 to 2 weeks. This is to check if the methotrexate is working and if it's causing any side effects. Your doctor may increase or decrease your methotrexate dose, depending on the results of your tests.

Why is methotrexate used for ectopic pregnancy?

So, methotrexate is used to treat an ectopic pregnancy because it stops the embryo's cells from growing and dividing, which eventually ends the pregnancy. Methotrexate injection is the favored medicine for treating ectopic pregnancies when surgery is not necessary. Methotrexate is a type of medicine called a folic acid antagonist.

What are the complications of ectopic pregnancy?

Complications of an ectopic pregnancy include possible rupture of the fallopian tube and severe internal bleeding. Ectopic pregnancies can be life-threatening. Because an ectopic pregnancy can be life-threatening, it’s important to diagnose and treat it promptly.

How long does it take for methotrexate to work?

The ectopic pregnancy is slowly absorbed in the body and ends when the level of hCG in the blood is zero. This usually takes about 4 to 6 weeks to complete.

What is ectopic pregnancy?

The term ectopic pregnancy is used for any pregnancy where the fertilized egg implants somewhere other than the uterine lining. The most common location for ectopic pregnancies to occur is the fallopian tube. It is estimated that 1.5% to 2% of pregnancies are ectopic. Complications of an ectopic pregnancy include possible rupture ...

How does methotrexate work?

Methotrexate is a type of medicine called a folic acid antagonist. It works by blocking an enzyme, dihydrofolate reductase, which is involved in making cellular proteins. By blocking this process, methotrexate keeps cells from copying themselves and dividing into more cells. In terms of an ectopic pregnancy, methotrexate stops ...

How long does methotrexate affect your body?

Sores in the mouth. Lower white blood cell count may also be found on blood tests. Because methotrexate can cause birth defects, the manufacturer recommends using effective birth control for at least 3 months after receiving methotrexate.

What are the side effects of methotrexate?

Common side effects of methotrexate are: 1 Nausea 2 Stomach distress 3 Sores in the mouth

What is the best treatment for ectopic pregnancy?

An early ectopic pregnancy without unstable bleeding is most often treated with a medication called methotrexate, which stops cell growth and dissolves existing cells. The medication is given by injection. It's very important that the diagnosis of ectopic pregnancy is certain before receiving this treatment.

What are the symptoms of ectopic pregnancy?

However, emergency medical help is needed if you develop these warning signs or symptoms of an ectopic pregnancy: Severe abdominal or pelvic pain accompanied by vaginal bleeding. Extreme lightheadedness. Fainting. Call 911 (or your local emergency number) or go to the hospital if you have the above symptoms.

How to prevent ectopic pregnancy?

Depending on your symptoms and when the ectopic pregnancy is discovered, this may be done using medication, laparoscopic surgery or abdominal surgery.

How long does it take for a blood test to confirm pregnancy?

This blood test may be repeated every few days until ultrasound testing can confirm or rule out an ectopic pregnancy — usually about five to six weeks after conception.

How to cope with losing a pregnancy?

Losing a pregnancy is devastating, even if you've only known about it for a short time. Recognize the loss, and give yourself time to grieve. Talk about your feelings and allow yourself to experience them fully. Rely on your partner, loved ones and friends for support.

Can a doctor diagnose ectopic pregnancy?

However, your doctor can't diagnose an ectopic pregnancy by examining you. You'll need blood tests and an ultrasound.

Can you get another HCG test after ectopic pregnancy?

It's very important that the diagnosis of ectopic pregnancy is certain before receiving this treatment. After the injection, your doctor will order another HCG test to determine how well treatment is working, and if you need more medication.

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