Treatment FAQ

lymphoma, which would need immediate treatment

by Kariane Lubowitz Published 2 years ago Updated 2 years ago
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Medication

Which chemo drugs are used to treat non-Hodgkin lymphoma?

  • Alkylating agents
  • Corticosteroids
  • Platinum drugs
  • Purine analogs
  • Anti-metabolites
  • Anthracyclines
  • Others. Often drugs from different groups are combined. ...
  • Intrathecal chemo. Most chemo drugs given systemically (IV or by mouth) can’t reach the cerebrospinal fluid (CSF) and tissues around the brain and spinal cord.

Procedures

These doctors could include:

  • A medical oncologist or hematologist: a doctor who treats lymphoma with chemotherapy, immunotherapy, and targeted therapy.
  • A radiation oncologist: a doctor who treats cancer with radiation therapy.
  • A bone marrow transplant doctor: a doctor who specializes in treating cancer or other diseases with bone marrow or stem cell transplants.

Therapy

today announced that the European Commission has granted Orphan Drug Designation to VIP152, the Company’s PTEFb/CDK9 inhibitor, for the treatment of diffuse large B-cell lymphoma (DLBCL).

Self-care

For patients with fast-growing lymphomas (such as diffuse large B-cell lymphoma), the disease can be cured with combination chemotherapy. For patients who do not respond to treatment or have early relapses, however, the disease can be fatal in a relatively short amount of time.

Nutrition

What treatment is usually used to treat lymphoma?

What is the best treatment for lymphoma?

What drugs are used to treat lymphoma?

Can lymphoma kill you?

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Is lymphoma a medical emergency?

Non-Hodgkin lymphoma (NHL) is often diagnosed after emergency presentation, a route associated with poor survival and an indicator of diagnostic delay.

Can lymphoma present acutely?

Aggressive NHLs usually present acutely or subacutely with a rapidly growing mass, systemic B symptoms (fever, night sweats, weight loss), and/or elevated levels of serum lactate. Treatment in these cases should be treated promptly to manage symptoms, slow or revert progression, and optimize survival.

Which one of the following lymphomas may not require immediate treatment?

A slow-growing lymphoma (such as follicular lymphoma) may not require immediate treatment.

Which is worse non-Hodgkin's lymphoma or Hodgkin's lymphoma?

Non-Hodgkin lymphoma is the seventh most diagnosed cancer, accounting for an estimated 72,500 cases in 2016. More than 86 percent of patients diagnosed with Hodgkin lymphoma survive five years or more. About 70 percent of patients diagnosed with non-Hodgkin lymphoma survive five years or more.

Is Hodgkin's lymphoma urgent?

Your GP should arrange for you to see a specialist if you have symptoms that could be due to Hodgkin lymphoma. Depending on your symptoms and other factors, this might be an urgent referral.

What can be mistaken for lymphoma?

Conditions that non-Hodgkin Lymphoma is commonly misdiagnosed as include:Influenza.Hodgkin's lymphoma.Cat scratch fever.HIV.Infections.Mononucleosis.

What are the 3 main types of lymphoma?

Each type of lymphoma can cause different symptoms and need different treatment.Hodgkin lymphoma. ... Non-Hodgkin lymphoma. ... Chronic lymphocytic leukaemia (CLL) and small lymphocytic lymphoma (SLL) ... Lymphoma in children and young people.

What is non-Hodgkin's lymphoma vs Hodgkin's lymphoma?

If in examining the cells, the doctor detects the presence of a specific type of abnormal cell called a Reed-Sternberg cell, the lymphoma is classified as Hodgkin's. If the Reed-Sternberg cell is not present, the lymphoma is classified as non-Hodgkin's.

What's the difference between Hodgkin's and non-Hodgkin's?

The primary difference between Hodgkin and non-Hodgkin lymphoma is the type of lymphocyte that is affected. Hodgkin lymphoma is marked by the presence of Reed-Sternberg lymphocytes, which a physician can identify using a microscope. In non-Hodgkin lymphoma, these cells are not present.

What type of lymphoma is not curable?

Lymphoplasmacytic lymphoma or Waldenstrom macroglobulinemia. This is a rare, slow-growing type of lymphoma. It's found mainly in the bone marrow, lymph nodes, and spleen. This type of lymphoma can't be cured.

Which type of lymphoma is worse?

The type of chemotherapy you receive will depend on how aggressive the cancer is. “T-cell non-Hodgkin lymphomas tend to be more aggressive,” Strati says. “Whereas B-cell non-Hodgkin lymphomas may be more slow-growing.”

Where does lymphoma spread to first?

NHL usually starts in an area of lymph nodes. When it spreads to an organ or tissue outside of the lymph nodes, it is called extranodal spread.

What is it called when lymphoma returns?

As explained in the Stages section, if the cancer returns after the original treatment, it is called recurrent cancer .

What is the best doctor for lymphoma?

A medical oncologist or hematologist is most often the primary cancer specialist for people with lymphoma. Common ways to give systemic therapies include an intravenous (IV) tube placed into a vein using a needle or in a pill or capsule that is swallowed (orally).

What is Revlimid used for?

Lenalidomide (Revlimid) is a thalidomide analog used to treat follicular lymphoma and mantle cell lymphoma that have not been stopped by other treatments. Lenalidomide is also used to treat multiple myeloma and myelodysplastic syndromes.

What is cancer care team?

This is called a multidisciplinary team. Cancer care teams include a variety of other health care professionals, such as physician assistants, oncology nurses, social workers, pharmacists, counselors, dietitians, and others.

How does chemotherapy work for NHL?

Chemotherapy is the use of drugs to destroy cancer cells, usually by keeping the cancer cells from growing, dividing, and making more cells. It is the main treatment for NHL. A chemotherapy regimen, or schedule, usually consists of a specific number of cycles given over a set period of time.

What is standard of care for NHL?

This section explains the types of treatments that are the standard of care for NHL. “Standard of care” means the best treatments known. When making treatment plan decisions, you are encouraged to consider clinical trials as an option. A clinical trial is a research study that tests a new approach to treatment.

Why do doctors want to do clinical trials?

Doctors want to learn whether the new treatment is safe, effective, and possibly better than the standard treatment. Clinical trials can test a new drug, a new combination of standard treatments, or new doses of standard drugs or other treatments. Clinical trials are an option to consider for treatment and care for all stages of cancer.

What is the treatment for non-Hodgkin lymphoma?

Many people treated for non-Hodgkin lymphoma will receive some form of chemotherapy, radiation therapy, biologic therapy, immunotherapy, or a combination of these. Bone marrow, stem cell transplantation, or CAR T-cell therapy may sometimes be used.

How long does non-Hodgkin lymphoma last?

Although “indolent” or slow growing forms of non-Hodgkin lymphoma are not currently curable, the prognosis is still very good. Patients may live for 20 years or more following an initial diagnosis. In certain patients with an indolent form of the disease, treatment may not be necessary until there are signs of progression.

Is lymphoma a heterogeneous disease?

Blood cancers, including lymphoma, are extremely heterogeneous, and can involve a variety of treatment options, often in combination. Some form of chemotherapy, radiation therapy, immunotherapy, or a combination is typically used to treat Hodgkin lymphoma. Bone marrow or stem cell transplantation may also sometimes be done under special ...

Who Can do Watchful Waiting?

Watch and wait might be an option if you have one of these slow-growing types of B-cell lymphoma:

What Happens During Watchful Waiting?

You'll have checkups every 3 to 6 months with the medical team that treats your cancer. During these visits, your doctor will:

Pros

If you decide to do watchful waiting you can avoid -- or at least delay -- the side effects of treatment. Chemotherapy, for instance, can cause temporary hair loss, nausea, and mouth sores. Radiation may bring on fatigue and skin blisters.

Why do I need a stem cell transplant for lymphoma?

Lymphoma is caused by a malfunction in the white blood cells produced by your bone marrow. You might have a stem cell (bone marrow) transplant if lymphoma comes back or if treatment isn’t working well enough, called refractory disease.

What is clinical trial?

You may qualify to participate in a clinical trial, which is a research study to learn more about promising new treatments or supportive care therapies. The hope is to improve the quality of life and survivorship of cancer patients. Clinical trials can often offer patients the newest and most innovative therapies before they are widely available. Columbia Cancer offers many clinical trials for lymphoma, some of which are only available at our center. You can talk to your care team about whether a clinical trial is an option for you.

Can you have children after lymphoma treatment?

Lymphoma is often diagnosed in people in their 20s who may not have started families or aren’t finished having children. Lymphoma treatment can cause infertility. We work with fertility preservation specialists to help if you want to have children after treatment.

Do you need immediate treatment for indolent lymphoma?

If you have indolent lymphoma you might not need immediate treatment if you’re generally healthy and the lymphoma isn’t causing symptoms or interfering with other organs. Your doctor might call this watchful waiting, active surveillance, or “watch-and-wait.”

Can radiation therapy be used for lymphoma?

You might have radiation therapy as part of your treatment, sometimes in combination with or after chemotherapy, to directly target cancer in lymph nodes and surrounding tissue. Radiation therapy can also be used to target lymphoma outside of lymph nodes, including highly effective treatment of lymphoma of the stomach, eye, and skin. Recent advances in technologies allow our expert radiation oncologists and radiation therapists to effectively treat much smaller and more targeted parts of the body than has been done in the past, which minimizes side effects.

How long can you wait to get treatment for NHL?

"About half of all patients can put off treatment for at least 3 years," Abetti says. "Some patients can be in watch-and-wait mode for 10 years or more .". It's possible you'll never need treatment.

Can you wait to get treatment for non-Hodgkin's lymphoma?

It's an approach called "watch and wait," and it might be a choice for you if you don't have any pain or other symptoms. Your doctor will keep a close eye on your disease, and they won't start treatment ...

Can you wait to see a doctor for lymphoma?

Also, if you aren't very good about visiting your doctor, watch and wait may not be a good choice. If you wait too long to set up an appointment, your lymphoma may get worse. Pagination. 1.

Is it hard to accept that you're not actively treating your cancer?

There's a risk that your cancer may change to a fast-growing type. It may also be hard to accept that you're not actively treating your cancer. Tsai says many of his patients struggle with this, but they feel better when they learn that watch and wait is an accepted strategy.

Can you wait to see your doctor if you have a slow growing NHL?

Also, if you aren't very good about visiting your doctor, watch and wait may not be a good choice.

Lymphoma Prognosis

The outlook for people with lymphoma has never been better, thanks to advances in molecular and genetic tumor testing and improvements in understanding the biology of different lymphoma types.

Why choose Memorial Sloan Kettering for lymphoma treatment?

At Memorial Sloan Kettering, we are committed to providing all our patients with access to the most effective and innovative treatments. Our lymphoma patients have excellent outcomes and receive superior care.

How to get rid of lymphoma?

Physical. Even though nutrition and fitness do not inherently alter the course of lymphoma, eating right, exercising routinely , and quitting cigarettes can help you cope with the rigors of treatment and speed your recovery thereafter. Stress reduction is also key to your success.

What is the best diet for lymphoma?

There is no set "lymphoma diet." You simply need to maintain a healthy, balanced diet which includes complex carbohydrates (such as whole grains), lean protein, low-fat dairy, plenty of fruits and vegetables, and healthy monounsaturated and polyunsaturated fats.

What to do if you can't cope with depression?

If you are unable to cope and are feeling extreme anxiety or depression, do not hesitate to ask for a referral to a psychologist or psychiatrist who can provide you with one-on-one, group, or family counseling as well as medications to help stabilize your moods.

What does it feel like to hear the word "lymphoma"?

When first hearing the word "lymphoma," you may be hit by any number of emotions, ranging from panic and fear to anger or guilt. Or, you may just feel numb and be unable to process the news. All of these feelings are normal; there are no wrong or right ways to feel.

Why is lymphoma scary?

Receiving a diagnosis of lymphoma can be scary and confusing, in part because the disease has no set course. There are many different types of lymphoma, each with their own course of treatment and expected outcomes.

What to do if you don't understand what the doctor is telling you?

This includes understanding: What lymphoma is . What the diagnosis means.

Does smoking cause lymphoma?

Smoking has both a direct and indirect effect on lymphoma. One of the largest studies investigating the association between cigarettes and lymphoma found that smoking increased the risk of follicular lymphoma by 41% in women while increasing the risk of T-cell lymphoma in men by 67% compared to the general population. 3 

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Diagnosis

Treatment

Clinical Trials

Coping and Support

Medically reviewed by
Dr. Rakshith Bharadwaj
Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Treatments include medications, radiation therapy, and bone marrow transplant.
Medication

Chemotherapy: Drugs to kill cancer cells, either as pill or injected directly into the bloodstream through the veins (intravenous).

Methotrexate


Targeted drug therapy: Drugs that target a particular substance on the cancer cells are used to destroy them.

Bortezomib


Immunotherapy: Work by targeting various proteins on tumor cells.

Nivolumab

Procedures

Bone marrow transplantation: Also known as stem cell transplant, the therapy involves introducing healthy bone marrow stem cells from a donor.

Therapy

Radiation therapy:Uses powerful rays to kill cancer cells.

Self-care

Always talk to your provider before starting anything.

  • Get adequate rest
  • Eat a healthy and nutritious diet

Nutrition

Foods to eat:

  • NA

Foods to avoid:

  • NA

Specialist to consult

Oncologist
Specializes in the diagnosis and treatment of cancer.
Hematologist
Specializes in the study of the blood and blood disorders.

Preparing For Your Appointment

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Tests and procedures used to diagnose lymphoma include: 1. Physical exam.Your doctor checks for swollen lymph nodes, including in your neck, underarm and groin, as well as a swollen spleen or liver. 2. Removing a lymph node for testing.Your doctor may recommend a lymph node biopsy procedure to remove all or part of a …
See more on mayoclinic.org

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