Treatment FAQ

in a young infant with rsv bronchiolitis, which of the following would be the treatment of choice

by Miss Mae Hermann Published 2 years ago Updated 2 years ago

The most common cause is the respiratory syncytial virus (RSV). Bronchiolitis is a mild, self-limited infection in the majority of children but may sometimes progress to respiratory failure in infants. Bronchiolitis is managed supportively with hydration and oxygen. No specific medications treat the infection.

Treatment for infants with bronchiolitis caused by respiratory syncytial virus (RSV) includes supplemental oxygen, nasal suctioning, fluids to prevent dehydration, and other supportive therapies.Jan 15, 2004

Full Answer

What is RSV bronchiolitis in children?

Apr 01, 2022 · References. Treatment for infants with bronchiolitis caused by respiratory syncytial virus (RSV) includes supplemental oxygen, nasal suctioning, fluids to prevent …

What is the treatment for bronchiolitis in infants?

Abstract. Bronchiolitis is a common lower respiratory tract infection in infants and young children, and respiratory syncytial virus (RSV) is the most common cause of this infection. RSV …

What is bronchiolitis?

A 14-month-old child is admitted to the intensive care unit for treatment of severe bronchiolitis caused by respiratory syncytial virus (RSV). Which medication does the nurse anticipate will …

What is the prevalence of bronchiolitis in infants younger than one year old?

RSV bronchiolitis In the scenario of an infant with RSV bronchiolitis, which of the following would be the treatment of choice? Fluids and nutritional support and close monitoring

What is the treatment for RSV in infants?

Most babies and young children can be cared for at home: Remove sticky nasal fluids with a bulb syringe and saline drops. Use a cool-mist vaporizer to keep the air moist and make breathing easier. Give your little one fluids in small amounts throughout the day.Sep 22, 2021

What is the best antibiotic for RSV?

There are currently two drugs approved for RSV disease: palivizumab and ribavirin. Palivizumab binds with the protein present in the virus, forming a shield. As a result, they fail to infect human cells. On the other hand, ribavirin, an antiviral agent, prevents the multiplication of the virus.

What medication is used to treat RSV?

Medications to treat respiratory syncytial virus (RSV) infection include the antiviral drug ribavirin, which can be used in severe high-risk cases, and bronchodilators.Feb 25, 2019

What is bronchiolitis RSV?

Bronchiolitis is a lung infection that's usually caused by the respiratory syncytial virus (RSV), which produces swelling and mucus production in the small breathing tubes of your child's lungs. Infections are most common during the winter and typically affect children under two years of age.Sep 17, 2020

Do babies need antibiotics for bronchiolitis?

Bronchiolitis is a serious, potentially life-threatening respiratory illness commonly affecting babies. It is often caused by respiratory syncytial virus (RSV). Antibiotics are not recommended for bronchiolitis unless there is concern about complications such as secondary bacterial pneumonia or respiratory failure.Oct 9, 2014

Are there antivirals for RSV?

A drug called 4'-fluorouridine effectively treated both COVID-19 and respiratory syncytial virus, or RSV, in animals. The compound can be given in pill form once a day, making it a promising candidate for a treatment that could be given outside hospital settings.Dec 14, 2021

RSV in Very Young Infants

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What is the most common cause of bronchiolitis?

Prevention. References. Bronchiolitis is a common lower respiratory tract infection in infants and young children, and respiratory syncytial virus (RSV) is the most common cause of this infection. RSV is transmitted through contact with respiratory droplets either directly from an infected person or self-inoculation by contaminated secretions on ...

How long does it take for bronchiolitis to show symptoms?

Patients with RSV bronchiolitis usually present with two to four days of upper respiratory tract symptoms such as fever, rhinorrhea, and congestion, followed by lower respiratory tract symptoms such as increasing cough, wheezing, and increased respiratory effort.

How is RSV transmitted?

RSV is highly contagious and is transmitted through direct contact with respiratory droplets.

What is the treatment for bronchiolitis?

Treatment for infants with bronchiolitis caused by respiratory syncytial virus (RSV) includes supplemental oxygen, nasal suctioning, fluids to prevent dehydration, and other supportive therapies. High-risk children who should be hospitalized include those younger than three months and those with a preterm birth, cardiopulmonary disease, ...

What age should an infant be hospitalized for bronchiolitis?

High-risk infants who should be hospitalized include those younger than three months, those whose gestational age at birth was less than 34 weeks, and those with comorbid cardiopulmonary disease or immunodeficiency. 4

Does palivizumab reduce hospitalization rates?

Prophylaxis with RSV intravenous immune globulin or palivizumab, a human monoclonal antibody, can reduce hospitalization rates in high-risk patients, although difficulties with administering the medications and high costs may preclude their widespread use.

What is the leading cause of hospitalization in infants younger than one year?

In the United States, bronchiolitis related to respiratory syncytial virus (RSV) is the leading cause of hospitalization in infants younger than one year. While only 1 to 2 percent of infants with this condition are hospitalized, annual hospital costs for RSV infections are quite high. 1 Supportive care, attention to adequate hydration and, ...

What are the risk factors for prophylaxis?

Infants born at 32 to 35 weeks of estimated gestational age must have two of the following risk factors to be candidates for prophylaxis: attendance at a child-care center, school-aged siblings, exposure to environmental pollution, abnormalities of the airways, or severe neuromuscular problems.

How to tell if a child has RSV?

Most children with RSV infection develop mild to moderate symptoms and can be treated at home provided they have close supervision by parents or caregivers who have been informed of what to watch for . Specific signs of a worsening condition that should prompt parents to contact their physician include an increasing respiratory rate (especially more than 60 breaths per minute); onset of labored breathing indicated by use of accessory muscles, retractions, cyanosis, or flared nostrils; fewer wet diapers (may indicate inadequate hydration); or an overall worsening appearance.

Is nebulized epinephrine effective?

The recent AHRQ evidence report states that nebulized epinephrine is “possibly effective.” However, a recent randomized trial published after the AHRQ report was released had sufficient statistical power to demonstrate that nebulized epinephrine therapy does not significantly reduce the length of the hospital stay or the time until infants with bronchiolitis are ready for discharge. 12 [Evidence level A, randomized controlled trial (RCT)] If a trial of inhaled epinephrine is considered, this therapy should be discontinued if there is no significant improvement in clinical assessment within 30 minutes after the first treatment. 9

How long does it take for bronchiolitis to show symptoms?

Patients with RSV bronchiolitis usually present with two to four days of upper respiratory tract symptoms such as fever, rhinorrhea, and congestion, followed by lower respiratory tract symptoms such as increasing cough, wheezing, and increased respiratory effort.

What is the most common cause of respiratory syncytial virus?

Bronchiolitis is a common lower respiratory tract infection in infants and young children, and respiratory syncytial virus (RSV) is the most common cause of this infection. RSV is transmitted through contact with respiratory droplets either directly from an infected person or self-inoculation by contaminated secretions on surfaces. Patients with RSV bronchiolitis usually present with two to four days of upper respiratory tract symptoms such as fever, rhinorrhea, and congestion, followed by lower respiratory tract symptoms such as increasing cough, wheezing, and increased respiratory effort. In 2014, the American Academy of Pediatrics updated its clinical practice guideline for diagnosis and management of RSV bronchiolitis to minimize unnecessary diagnostic testing and interventions. Bronchiolitis remains a clinical diagnosis, and diagnostic testing is not routinely recommended. Treatment of RSV infection is mainly supportive, and modalities such as bronchodilators, epinephrine, corticosteroids, hypertonic saline, and antibiotics are generally not useful. Evidence supports using supplemental oxygen to maintain adequate oxygen saturation; however, continuous pulse oximetry is no longer required. The other mainstay of therapy is intravenous or nasogastric administration of fluids for infants who cannot maintain their hydration status with oral fluid intake. Educating parents on reducing the risk of infection is one of the most important things a physician can do to help prevent RSV infection, especially early in life. Children at risk of severe lower respiratory tract infection should receive immunoprophylaxis with palivizumab, a humanized monoclonal antibody, in up to five monthly doses. Prophylaxis guidelines are restricted to infants born before 29 weeks' gestation, infants with chronic lung disease of prematurity, and infants and children with hemodynamically significant heart disease.

How to care for a newborn in a hospital?

1. Place the infant in a private room. 2. Place the infant in a room near the nurses' station. 3. Ensure that the infant's head is in a flexed position. 4. Wear a mask at all times when in contact with the infant. 5.

How to get a baby to sleep in a room?

Place the infant in a room near the nurses' station. 3. Ensure that the infant's head is in a flexed position. 4. Wear a mask at all times when in contact with the infant. 5. Place the child in a tent that delivers warm, humidified air. 6. Position the infant side-lying, with the head lower than the chest.

How to treat RSV in infants?

1. Initiate strict enteric precautions. 2. Wear a mask when caring for the child. 3. Plan to move the infant to a room with another child with RSV. 4. Leave the infant in the present room, because RSV is not contagious.

Is RSV contagious?

4. Leave the infant in the present room, because RSV is not contagious. Rationale: RSV is a highly communicable disorder, but it is not transmitted via the airborne route. It is usually transferred by the hands, and meticulous handwashing is necessary to decrease the spread of organisms.

What does it mean when your chest is quiet?

A "quiet chest" after assessment of wheezing indicates occlusion of air pathways and impending respiratory arrest. All other options are within normal range for infants undergoing oxygen administration. The mother of an infant diagnosed with bronchiolitis asks the nurse what causes this disease.

Overview

Epidemiology

  • There are seasonal differences in the incidence of RSV infection in the United States, although the highest incidence occurs from December to March.6 Nearly all children have been infected with RSV at least once by two years of age. Most children have a self-limited course that responds to supportive home care; however, approximately 2% to 3% of infants younger than 12 months are …
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Signs and symptoms

  • Patients with RSV bronchiolitis usually present with two to four days of upper respiratory tract symptoms, such as fever, rhinorrhea, and congestion, followed by lower respiratory tract symptoms. Increasing cough is usually the first sign of lower respiratory tract involvement; later symptoms include tachypnea, dyspnea, increased respiratory effort, and difficulty feeding.1,2 Pa…
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Prognosis

  • RSV bronchiolitis has a more severe clinical course than non-RSV bronchiolitis, including a longer hospital stay.15 However, virologic testing on an individual basis is insufficient to predict outcomes and does not affect management decisions.15 Therefore, RSV testing should not be routinely performed except in hospitalized infants who are receiving monthly prophylaxis (so tha…
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Treatment

  • The mainstay of therapy for acute RSV bronchiolitis in infants and children is supportive care (Table 2). Oxygen saturation of 90% or more is sufficient for children with bronchiolitis.4 No data support the use of supplemental oxygen to maintain higher oxygen saturation, and doing so only prolongs hospitalization because of an assumed need for oxyg...
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Uses

  • Pulse oximetry alone is an unreliable measure of hypoxemia and respiratory distress, and continuous use is optional in infants and children with bronchiolitis.23 Continuous pulse oximetry lends to negative sleep effects on patients' families and alarm fatigue for families and staff. Its use is implicated in increased hospitalization rates without significant change in mortality.24
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Contraindications

  • Bronchodilators should not be administered to infants and children with bronchiolitis. Despite short-term improvement in clinical symptom scores, they have no effect on the need for hospitalization, oxygen saturation, length of hospitalization, or disease resolution.24,27 A 2014 Cochrane review of 30 randomized controlled trials found that infants with bronchiolitis who rec…
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Prevention

  • Educating parents on reducing the risk of infection is one of the most important things a physician can do to help prevent RSV infection, especially early in life. RSV is highly contagious and is transmitted through direct contact with respiratory droplets. Secretions can remain infectious for more than six hours on hard surfaces such as tabletops, cribs, and toys.2,4 Strict hand hygiene …
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