Treatment FAQ

how to help someone with chemo treatment for seminoma stage 2 cancer

by Aurelia Yost Published 2 years ago Updated 2 years ago

Usually stage II seminomas are given higher doses of radiation than stage I seminomas. Chemotherapy: Another option is chemo, with either 4 cycles of EP (etoposide and cisplatin) or 3 cycles of BEP (bleomycin, etoposide, and cisplatin). The doctor will then watch closely (every 3 to 6 months) for any signs that the cancer has come back.

Full Answer

What are the treatment options for Stage II seminoma?

Stage IIC seminomas. Treatment is typically chemotherapy with 4 cycles of EP (etoposide and cisplatin) or 3 or 4 cycles of BEP (bleomycin, etoposide, and cisplatin). Another option might be VIP (etoposide, ifosfamide, and cisplatin) for 4 cycles. Radiation therapy is generally not used for stage IIC seminoma.

What are the treatment options for Stage 2 cancer?

Testicular cancer is the most common solid malignancy affecting males aged 15 to 35 years. Germ cell tumors (GCTs), which account for 95 percent of testicular cancers, are one of the most curable solid neoplasms due to treatment advances that began in the late 1970s. GCTs can consist of one histologic pattern or a mix of multiple histologic types.

Can Stage 1 seminoma cancer come back?

Dec 01, 2017 · For all other patients with stage II disease, platinum-based chemotherapy with three cycles of bleomycin-etoposide-cisplatin (BEP), or four cycles of etoposide-cisplatin (EP) if there is a contraindication to bleomycin, is recommended. 63 Platinum-based chemotherapy is also recommended for patients with stage IIC or bulky stage IIB disease because of the high …

What is the treatment for stage IIc of testicular cancer?

Jan 21, 2019 · For seminomas, resection of tumours is done by surgery and the treatment to eliminate cancer from the remaining parts of the body could be chemotherapy or radiotherapy. If chemotherapy is given, 4 cycles of EP or 3 cycles of BEP is the usual practice.

Can Stage 2 testicular cancer be cured?

Overview. Patients with Stage II testicular seminoma have a curable cancer that involves the testis and the retroperitoneal lymph nodes. Retroperitoneal lymph node involvement is further characterized by the number of nodes involved and the size of involved nodes.

Does Stage 2 testicular cancer require chemo?

For stage 2 and 3 testicular cancers, 3 to 4 cycles of chemotherapy are given using a combination of different medications. Further surgery is sometimes needed after chemotherapy to remove any affected lymph nodes or deposits in the lungs or, rarely, in the liver.

Is seminoma completely curable?

Chemotherapy May Be as Effective as Radiation Therapy after Surgery. Stage I seminoma is a highly curable cancer, with cure rates in excess of 95%.

What is the survival rate of stage 2 testicular cancer?

Up to 96.6% of men treated for stage 2 testicular cancer survive five years, although up to 20% may have a recurrence.

Which is worse seminoma or nonseminoma?

Seminomas are very sensitive to radiation therapy. Nonseminoma: This more common type of testicular cancer tends to grow more quickly than seminomas. Nonseminoma tumors are often made up of more than one type of cell, and are identified according to these different cell types: Choriocarcinoma (rare)May 27, 2020

How many chemo treatments are used for testicular cancer?

Testicular cancer may be treated with 1 to 4 cycles of chemotherapy, depending on the stage of the cancer. During treatment, a patient may receive 1 drug at a time or a combination of different drugs given at the same time.

What is the prognosis of seminoma?

The 3-year survival rate for patients diagnosed with typical testicular seminoma was 100%, 93.8% for cases with testicular seminoma combined with embryonal carcinoma, and 84.6% for those with testicular seminoma combined with embryonal carcinoma and teratoma.Dec 30, 2015

What causes seminoma?

Later in development, germ cells in males are supposed to mature into sperm-producing cells within the testicles. If the germ cells don't mature as they are supposed to, they can sometimes change and multiply uncontrollably to form a seminoma or non-seminoma.3 days ago

What is metastatic seminoma?

Abstract. Retroperitoneal metastasis of seminoma often occurs in the higher stage through lymph nodes. Generally, seminoma expresses specific germ cell markers while being negative for carcinoma markers. We present a unique case of cytokeratin positive seminoma initially presented as retroperitoneal metastasis.

How is Stage 2 testicular cancer treated?

Treatment of Stage II Testicular Cancer

When the tumor is 5 centimeters or smaller: Surgery to remove the testicle, followed by radiation therapy to lymph nodes in the abdomen and pelvis. Combination chemotherapy. Surgery to remove the testicle and lymph nodes in the abdomen.
Dec 16, 2021

Can you survive metastatic testicular cancer?

Testicular cancers are highly curable, even in patients with metastatic disease at diagnosis. According to SEER data from 2009-2015, overall 5-year survival is 95.2%.Sep 11, 2019

What chemo is used for testicular cancer?

The chemo regimens most commonly used as the first treatment for testicular cancer are: BEP (or PEB): bleomycin, etoposide, and cisplatin. EP: etoposide and cisplatin. VIP: VP-16 (etoposide) or vinblastine plus ifosfamide and cisplatin.May 17, 2018

Carcinoma in Situ (Stage 0) Testicular Tumors

In this stage, the cancer has not spread outside the testicle, and your tumor marker levels (like HCG and AFP) are not elevated. If CIS is diagnose...

Stage III Seminomas and Non-Seminomas

Even though stage III tumors have spread by the time they are found, most of them can still be cured.Both stage III seminomas and non-seminomas are...

Recurrent Testicular Cancer

If the cancer goes away with treatment and then comes back, it's said to have recurred or relapsed. If this happens, it’s usually within the first...

Sertoli Cell and Leydig Cell Tumors

Typically, radical inguinal orchiectomy is the treatment for Sertoli cell and Leydig cell tumors. Radiation therapy and chemo generally don't work...

More Treatment Information For Testicular Cancer

For more details on treatment options – including some that may not be addressed here – the National Comprehensive Cancer Network (NCCN) and the Na...

What is the treatment for stage 2 seminoma?

The primary treatment of Stage II seminoma is surgical removal of the cancer by orchiectomy followed by adjuvant therapy to reduce the risk of cancer recurrence. The following is a general overview of treatment for Stage II seminoma.

Can stage 2 seminoma be detected?

It is important to understand that some patients with Stage II seminoma already have small amounts of cancer that have spread into the lymph nodes and cannot be detected with any of the currently available tests. Undetectable areas of cancer that remain after surgery are referred to as micrometastases. The presence of micrometastases causes cancer ...

What is stage 2 testicular seminoma?

Patients with Stage II testicular seminoma have a curable cancer that involves the testis and the retroperitoneal lymph nodes. Retroperitoneal lymph node involvement is further characterized by the number of nodes involved and the size of involved nodes. Patients with Stage II seminoma are often divided into “bulky” and “non-bulky” ...

Is stage 2 testicular seminoma curable?

Patients with Stage II testicular seminoma have a curable cancer that involves the testis and the retroperitoneal lymph nodes. Retroperitoneal lymph node involvement is further characterized by the number of nodes involved and the size of involved nodes. Patients with Stage II seminoma are often divided into “bulky” and “non-bulky” for treatment planning.

What is multimodality cancer treatment?

Cancer treatment may consist of surgery, radiation, chemotherapy, targeted therapy, or a combination of these treatment techniques. Combining two or more of these treatment techniques–called multi-modality care–has become an important approach for increasing a patient’s chance of cure and prolonging survival.

What is the undetectable area of cancer that remains after surgery?

Undetectable areas of cancer that remain after surgery are referred to as micrometastases. The presence of micrometastases causes cancer recurrence following treatment with surgery alone. An effective treatment is needed to cleanse the body of micrometastases in order to improve a patient’s duration of survival and potential for cure. ...

What is the cure rate for non-bulky cancer?

This results in a cure rate of more than 90% . One of the controversies in management of Stage II seminoma is how much surveillance is necessary in patients who have received radiation therapy since the recurrence rate is so low.

What is the treatment for stage 2 seminoma?

Stage IIA seminomas. Radiation: After surgery to remove the testicle (radical inguinal orchiectomy), one treatment option is radiation to the retroperitoneal lymph nodes. These are the lymph nodes at the back of the abdomen (belly). Usually stage II seminomas are given higher doses of radiation than stage I seminomas.

How often do you have to watch for stage 2 seminoma?

The doctor will then watch closely (every 3 to 6 months) for any signs that the cancer has come back .

What is stage 0 testicular cancer?

Carcinoma in situ (stage 0) testicular tumors. In this stage, the cancer has not spread outside the testicle, and tumor marker levels (like HCG and AFP) are not elevated. If CIS is diagnosed after surgery removes the testicle, no other treatment is needed. If CIS is found after a testicular biopsy (such as for fertility problems), ...

Can chemo cure cancer?

The cancer will come back in about 15% to 20% of patients, most often as spread to lymph nodes, but if it does, radiation or chemo can still usually cure the cancer. Radiation therapy: Radiation aimed at para-aortic lymph nodes is another option.

Can you get chemo for cancer in lymph nodes?

If cancer is found in the lymph nodes, chemo is often recommended depending on the number of nodes with cancer in them. (See below.) Chemotherapy: Instead of surgery, the doctor may recommend 1 cycle of the BEP regimen (bleomycin, etoposide, and cisplatin). This can help reduce the risk that the cancer will come back.

How many cycles of chemo for cancer?

This may be either 3 cycles of BEP (bleomycin, etoposide, and cisplatin) or 4 cycles of E P (etoposide and cisplatin).

What is stage IIB seminoma?

Stage IIB seminomas. These seminomas have spread to cause larger lymph nodes or have spread to many different lymph nodes. Chemotherapy: This is typically the preferred treatment. It is usually either 4 cycles of EP (etoposide and cisplatin) or 3 cycles of BEP (bleomycin, etoposide, and cisplatin).

What percentage of testicular cancer is a germ cell tumor?

Germ cell tumors (GCTs), which account for 95 percent of testicular cancers, are one of the most curable solid neoplasms due to treatment advances that began in the late 1970s. GCTs can consist of one histologic pattern or a mix of multiple histologic types. Testicular GCTs are divided into two groups:

What is the most common cancer in men?

Testicular cancer is the most common solid malignancy affecting males aged 15 to 35 years. Germ cell tumors (GCTs), which account for 95 percent of testicular cancers, are one of the most curable solid neoplasms due to treatment advances that began in the late 1970s.

How many cycles of EP for stage IIB testicular cancer?

If chemotherapy is given, 4 cycles of EP ...

What is the staging system for testicular cancer?

Staging standardizes the process of describing how much the cancer has spread in the body and this is an important step to determine the best course of action for the disease. Most cancers that have tumours are staged using a staging system called TNM system. For staging testicular cancer, this system is slightly modified to account for level ...

What is testicular cancer?

January 21, 2019 4 Mins Read. Testicular cancer is the cancer in the testicles, the male reproductive organ that makes hormones and sperm. To learn more about testicular cancer, read here.

What is the cancer in the testicles?

Testicular cancer is the cancer in the testicles, the male reproductive organ that makes hormones and sperm. To learn more about testicular cancer, read here.

Where does testicular cancer spread?

Testicular cancer spreads into the spermatic cord and scrotum. When the patient’s blood sample is tested for tumour marker levels, it will be observed to be slightly higher than normal in stage II of testicular cancer.

Can testicular cancer spread to the spermatic cord?

The testicular cancer might have spread into the spermatic cord or scrotum as well. For seminomas, radical inguinal orchiectomy followed by radiation therapy to the retroperitoneal lymph nodes is the recommended course of treatment. Chemotherapy may also given in a few cases with 4 cycles of EP or 3 cycles of BEP.

How many men survive testicular cancer?

Stage II of testicular cancer is a very curable form of cancer. 95 out of every 100 men treated with testicular cancer in stage II have survived, that is, it has a survival rate of 95%. The survival rate of the cancer completely depends on the type of treatment the patients have been given along with a lot of other factors.

What is stage 2 cancer?

Stage II cancer refers to larger tumors or cancers that have grown more deeply into nearby tissue. In this stage, the cancer may have spread to the lymph nodes, but not to other parts of the body. At Cancer Treatment Centers of America ® (CTCA), our cancer experts recognize that stage II cancer is a complex disease. We use a variety of sophisticated tests and procedures to measure the stage of the disease, and to design a comprehensive treatment plan tailored to your diagnosis and individual needs.

Does stage 2 cancer spread to other parts of the body?

In this stage, the cancer may have spread to the lymph nodes, but not to other parts of the body. At Cancer Treatment Centers of America ® (CTCA), our cancer experts recognize that stage 2 cancer is a complex disease.

Can breast cancer be detected during a self-exam?

The cancer cells have spread beyond the original location and into the surrounding breast tissue, and a tumor may be detected during a breast self-exam as a hard lump. Learn more about breast cancer stages.

What does stage 2 mean in lung cancer?

In non-small cell lung cancers, which account for more than 80 percent of lung cancer diagnoses, stage 2 means the cancer may have spread to nearby lymph nodes or into the chest wall. Learn more about lung cancer stages.

Does colorectal cancer spread to lymph nodes?

Cancer has grown through the outermost layer of the colon or rectum and may have grown through it and into nearby organs or tissues. It has not spread to the lymph nodes or distant organs. Learn more about colorectal cancer stages.

Is brain cancer graded or staged?

Some cancers, such as blood cancers, and brain and spinal cord tumors, use different staging systems. For instance, brain cancer is usually graded rather than staged, based on factors including: The size and location of the tumor. The type of tissues or cells affected.

What is grade 2 brain cancer?

The spread of the cancer. The possibility the cancer has spread beyond the brain or central nervous system. In grade 2 brain cancer, the tumor grows slowly but may spread into nearby tissues or recur.

What to do when someone is in cancer treatment?

Cook, clean, mow the lawn, wash the laundry and/or dishes, make sure the bills get paid, get the kids dressed for school, walk the dog and do all of the things that the person in cancer treatment would normally do to keep life going for the rest of the family. Bring a cup of tea or coffee and stop by for a visit.

How to help someone with cancer?

Help keep their household running. Cook, clean, mow the lawn, wash the laundry and/or dishes, make sure the bills get paid, get the kids dressed for school, walk the dog and do all of the things that the person in cancer treatment would normally do to keep life going for the rest of the family. Bring a cup of tea or coffee and stop by for a visit.

How to help a cancer patient who doesn't feel like talking?

Instead, listen to the patient’s concerns, acknowledge that cancer sucks and offer a shoulder to cry on. And if the patient doesn’t feel like talking, sit there with them quietly. There is a lot of power in simply being present.

How to help a cancer patient who doesn't want to be treated differently?

Talk to your friend or loved one like you did before. Tell jokes, talk about what’s going on in the neighborhood or at your kids’ school, favorite TV shows, etc. This can briefly help take patients’ minds off of cancer.

How to help a cancer patient with stress?

Take them to school or sports practice, help with homework, or have them over for a slumber party or playdate. This can help take their minds off of cancer, and ease their parents’ stress. Knit a cap or scarf. Pray. This gives many patients the courage to face another day. Just sit with them and listen.

Can you give chemo after esophageal cancer?

Radiation may not be an option if it was already given as part of the initial treatment. If chemotherapy was given before, it is usually still possible to give more chemotherapy.

What is the first treatment for gastroesophageal junction cancer?

If chemoradiation isn’t an option, chemotherapy, immunotherapy, or a combination of the two might be used. For people with gastroesophageal junction cancers that are HER2 positive, immunotherapy with pembrolizumab, plus chemotherapy, plus the targeted drug, trastuzumab , might be used as the first treatment.

What is stage 0 esophagus cancer?

Treating stage 0 esophagus cancer. A stage 0 tumor contains abnormal cells called high-grade dysplasia and is a type of pre-cancer. The abnormal cells look like cancer cells, but they are only found in the inner layer of cells lining the esophagus (the epithelium). They have not grown into deeper layers of the esophagus.

What is stage 0 cancer?

A stage 0 tumor contains abnormal cells called high-grade dysplasia and is a type of pre-cancer. The abnormal cells look like cancer cells, but they are only found in the inner layer of cells lining the esophagus (the epithelium). They have not grown into deeper layers of the esophagus. This stage is often diagnosed when someone with Barrett’s esophagus has a routine biopsy.

Can T1 cancer be removed?

But most patients with T1 cancers who are healthy enough will have surgery (esophagectomy) to remove the part of their esophagus that contains the cancer. Chemotherapy and radiation therapy given at the same time (chemoradiation) may be recommended after surgery if there are signs that all of the cancer may not have been removed. ...

What is the treatment for cancer in the neck?

If the cancer is in the upper part of the esophagus (in the neck), chemoradiation may be recommended as the main treatment instead of surgery.

Can chemo be used to treat cancer in the neck?

If the cancer is in the upper part of the esophagus (in the neck), chemoradiation may be recommended as the main treatment instead of surgery. For some patients, this may cure the cancer. Close follow-up with endoscopy is very important in looking for possible signs of cancer returning. People with stage I cancers who can’t have surgery ...

Overview

Adjuvant Therapy

  • It is important to understand that some patients with Stage II seminoma already have small amounts of cancer that have spread into the lymph nodes and cannot be detected with any of the currently available tests. Undetectable areas of cancer that remain after surgery are referred to as micrometastases. The presence of micrometastases causes cancer ...
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Non-Bulky Cancers

  • Patients with non-bulky disease have cancers involving the lymph nodes that are less than 5 centimeters (2 inches) in greatest dimension measured on a computed tomography (CT) scan. The standard treatment for non-bulky cancers consists of radiation to the retroperitoneal lymph nodes following surgical orchiectomy. This results in a cure rate of more than 90%. One of the c…
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Bulky Disease

  • Patients with bulky disease have cancers involving the lymph nodes that are greater than 5 centimeters (2 inches) in greatest dimension when measured on a CT scan. Standard therapy for bulky disease utilizes a Platinol®(cisplatin)-based combination chemotherapy regimen or radiation therapy to the abdominal and pelvic lymph nodes following surgical orchiectomy. In th…
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Strategies to Improve Treatment

  • The progress that has been made in the treatment of testicular cancer has resulted from improved development of chemotherapy and radiation treatments in patients with more advanced stages of cancer and participation in clinical trials. Future progress in the treatment of testicular cancer will result from continued participation in appropriate clinical trials. Supportive Care: Sup…
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