Treatment FAQ

how to apply efudex treatment

by Leila Marquardt Published 2 years ago Updated 2 years ago
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Directions for Using Efudex

  • Two times daily, apply the medicine very thinly to the treatment area with your fingertip and massage it in well.
  • Afterward, wash your finger thoroughly with water.
  • Do not get 5-FU in your eyes, and do not use it on your eyelids.
  • Keep 5-FU off your eyelids.
  • Use 5-FU with care in the area between the nose and cheeks since the medicine may...

Apply the cream with a clean fingertip. If you are treating your whole face, use four pea-sized amounts of cream; one on the chin, each cheek and the forehead. For selected areas, just use one pea-sized amount of cream. Wash your hands after applying the Efudix cream.

Full Answer

How long does one need to apply Efudex for results?

You can apply a small amount of makeup 20 minutes after applying Efudix, as long as the skin is not broken or irritated The duration of treatment depends on the skin condition. Typically it takes 2-3 weeks for the face, 4-6 weeks for the scalp, arms and legs Suggestions for using Efudex or Fluoroplex (5% or 1%) Use the medication as directed by your physician.

How to use Efudex and what to expect?

Tips for sleeplessness

  • Accomplish any physically demanding jobs prior to beginning treatment.
  • Rest as much as work and home life allow.
  • Use Benadryl at night to help with the itching as well as the sleeplessness.

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What is the average recovery time after you stop using Efudex?

The medication is usually applied to the effected area until the point where the old skin comes off or a lesion forms, and it is at around this time that your doctor will ask you to stop using Efudex. After the period of treatment, which usually lasts two to four weeks, you need another one to two months of healing.

When should I stop using Efudex treatment?

When should I stop using efudex treatment?

  • Wait anywhere from 30 minutes to an hour after washing to apply any lotion or cream.
  • Anything burns when first applied.
  • Vanicream Lite Lotion is my go-to.
  • Wash with water and mild soap in the shower and do not rub the area.
  • The ten minutes following a shower or washing are key.

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Should Efudix cream be rubbed in?

How to apply the Efudix cream? - Wash the skin with lukewarm water. After your skin is completely dry, apply a thin film of the cream to the affected skin and rub it gently onto your skin. Apply a small amount of medication to the affected skin, using just enough to cover the area with a thin film.

How long do you leave Efudex on?

Unless your doctor tells you to stop using Efudix continue treatment up until the ulceration stage, usually 3 to 4 weeks. The healing process is usually complete 1 to 2 months after the end of treatment.

How long does it take for Efudix cream to work?

The usual duration of treatment for an initial course of therapy is three to four weeks, but this may be prolonged. Lesions on the face usually respond more quickly than those on the trunk or lower limbs whilst lesions on the hands and forearms respond more slowly.

What should I put on skin after Efudix treatment?

The day after your last Efudex application, begin moisturizing all treated areas with either Vaseline or Aquaphor Healing Ointment (over the counter). Apply frequently every day to keep skin soft. The treated area can be pink for several months and is more susceptible to getting sun burned.

Is 2 weeks enough for Efudex?

After 2-4 weeks your skin will be red, crusty, and uncomfortable; this is what we want to happen. In some cases, such as for lesions on the backs of the hands, the body, or for basal cell carcinoma, it might take longer to get to this stage (4-6 weeks). The cream can then be stopped, to allow healing.

Does skin look better after Efudex?

Patients getting such treatment have also reported softer, smoother, less wrinkled skin -- and now, a new study confirms those skin improvements. The study included 21 patients with actinic keratoses who applied a 5% fluorouracil skin cream called Efudex to their entire face twice daily for two weeks.

What does the erosion stage of Efudex look like?

What does it look like? Since most Efudex users experience redness and irritation, I will start there. Erosion, for me, means that the entire area I am treating is bright red but contains much darker spots where the actinic keratoses are most concentrated. These darker spots tend to pucker and may even begin to scab.

How painful is Efudex?

Itching, burning and irritated skin This is, without a doubt, the hallmark of Efudex. As the damaged skin is treated and precancerous cells surface, the skin can become unbearably painful.

How do you know when to stop Efudex?

Erythema develops in several days. After continued application, the damaged skin becomes painful and inflamed with a beefy-red appearance with erosions and crusting. At this point, the medication should be stopped.

How do I know if Efudex has worked?

The area of abnormal skin becomes very red and inflamed; this may progress to erosions and scabbing, followed by healing. This process shows the Efudix is working. After stopping treatment, your skin will need to heal and the treated area may remain red for a while.

Can you put Vaseline over Efudex?

You may apply Aquaphor, Vaseline, or over-the-counter Hydrocortisone ointment to the area treated after applying Efudex. Do not apply prior to Efudex application.

Can I use a moisturizer while using Efudex?

After using fluorouracil cream, wait 2 hours before applying sunscreen or moisturizer to the treated area. Do not use other skin products including creams, lotions, medications, or cosmetics unless instructed by your doctor to do so.

When to apply a cream twice a day?

Set aside the same time daily to apply. When on a twice a day routine, I apply in the morning after I have allowed my skin to dry thoroughly. Following a shower in the evening, I allow my skin to dry and apply the cream about an hour or so before bed.

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This article represents the opinions, thoughts, and experiences of the author; none of this content has been paid for by any advertiser. The SkinCancer.net team does not recommend or endorse any products or treatments discussed herein. Learn more about how we maintain editorial integrity here.

Is there a community for Efudex?

Going forward with your little tube, know this. There exists an entire community of skin cancer patients charged with the same instructions to pick up Efudex on the way home, apply it daily, and wait. If you are feeling lost, confused, and a bit overwhelmed, the rest of us are here for you. Our online communities are waiting to help you address your questions. Facebook, as well, boasts support groups set up to attend to the needs of Efudex users like you. Reach out, we are here.

Is Efudex a topical cream?

A little goes a long way as Efudex is a potent topical chemotherapy cream.

Why do you need to apply Efudex?

Continue to apply Efudex in the most sanitary way possible to prevent any cross contamination and monitor your lesions closely. When the diseased skin is dying, it will swell, peel, crust over and is likely to burn. This process has to occur for the old skin to die and a new, healthy skin layer to form.

What is Efudex cream?

How to Use Efudex Cream. Share on Facebook. Efudex is a brand name for a topical skin growth treatment known generically as fluorouracil. Doctors prescribe it for both benign skin growths and malignant tumors.

How long does it take for Efudex to work?

During the first week, the areas of Efudex-treated skin will appear red and inflamed. This indicates that the medicine is working. Benign skin growth may require Efudex application for two to four weeks while three to six weeks of medicine may be necessary for cancerous tumors. Attend physician-scheduled follow-up visits.

How to treat skin lesions?

Treat your skin lesions twice a day, preferably morning and evening. Wash the area of skin overgrowth with either mild soap and water or a physician-prescribed cleansing solution. Wash and dry your hands thoroughly and put on disposable gloves. Apply enough Efudex cream to completely cover the affected area of skin.

Why is it important to cover Efudex?

Complete coverage is important so the medicine can penetrate and stop the growth of all skin cells in the area of overgrowth. For cancer patients, untreated cells will proliferate and possibly metastasize. Wash the remaining Efudex cream from the gloves to prevent healthy skin from touching the medication.

How long does it take for skin to heal after Efudex?

Long after your prescription has ended, the skin's healing process will continue and result in the formation of new skin within one to three months after the last Efudex application.

Who is Sarah McLeod?

McLeod holds a Bachelor of Arts in human services from George Washington University and a Master of Science in health science from Touro University.

What is Efudex 5FU?

Efudex (abbreviated 5-FU) has the ability to destroy pre-cancerous skin cells. Applying 5-FU to the skin removes the rough spots resulting form sun damage (Actinic Keratosis). The skin is then smoother and more youthful looking.

Where to use 5-FU?

Use 5-FU with care in the area between the nose and cheeks since the medicine may irritate the folds around your nostrils.

How long does it take for skin to heal after 5 FU?

These raw areas results from the destruction of defective skin cells. They are a necessary part of 5-FU treatment. The treatment usually continues for 2-4 weeks.

How long does it take for a 5-FU to work?

They are a necessary part of 5-FU treatment. The treatment usually continues for 2-4 weeks. When treatment is stopped, your skin will heal rapidly; in 2-3 weeks healthy new skin will have replaced the sun-damaged skin destroyed by the 5-FU.

Can you use makeup before applying makeup?

You may use makeup. Be sure to apply the 5-FU before applying makeup.

Can you use 5-FU with eyes?

CAUTION: 5-FU is a powerful, destructive medication and must be used exactly as directed. Keep it away from eyes and mouth. Keep your 5-FU locked so other people can not mistakenly use it.

How Effective Is Efudex?

3 Efudex cream achieves success rates similar to Aldara ( imiquimod ), another topical cream used for treating skin cancer.

What is Efudex used for?

Indications. Efudex is a topical cream used for the treatment of superficial basal cell carcinoma when conventional methods are impractical, such as in the case of multiple lesions or difficult treatment sites on the face or scalp. It is also used to treat actinic keratosis (also called solar keratosis), which can lead to more serious invasive ...

What is the effect of Efudex on cancer cells?

Efudex is a chemotherapy drug (an "antimetabolite") that interferes with the formation of DNA and RNA, which are essential for cell division and growth. 2  This inhibition results in the death of quickly growing cancerous cells, which absorb more fluorouracil than healthy cells.

What is fluorouracil used for?

1 . In its more potent injectable form, fluorouracil is also used to treat breast, stomach, bowel, and esophageal cancers .

How long does it take for fluorouracil to work on basal cell carcinoma?

For basal cell carcinoma, it is recommended that 5-percent fluorouracil cream be applied two times per day in an amount sufficient to cover the lesions for at least three to six weeks. Therapy may be required for as long as 10 to 12 weeks before the lesions disappear, however. 1 

Does Efudex leave scars?

The success rate of treating basal cell carcinoma with fluorouracil is approximately 90 percent to 93 percent 3 . And unlike surgery, Efudex is not likely to leave scars or permanently discolor patches of skin.

Can you use efudex in the sun?

Avoid sunlight as much as possible while using Efudex since it may increase your side effects. If exposed to the sun, wear a hat and use sunscreen.

How should I use Efudex?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

What is Efudex?

Efudex (for the skin) is used to treat scaly overgrowths of skin (actinic or solar keratosis ).

How to get rid of fluorouracil in eyes?

Rinse with water or saline if this medicine gets in your eyes. Do not let Efudex build up in the skin folds around your mouth, nose, or eyes. Use caution when applying the medicine around these areas. Avoid using other medications on the areas you treat with fluorouracil unless your doctor tells you to.

Can Efudex cause hives?

Efudex side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using Efudex and call your doctor at once if you have: severe pain or swelling of treated skin; severe itching, burning, or irritation; new or worsening skin sores;

Can you breastfeed while taking Efudex?

Use effective birth control to prevent pregnancy while you are using this medicine. You should not breastfeed while using Efudex. Efudex is not approved for use by anyone younger than 18 years old.

Can you use fluorouracil with other medications?

Avoid using other medications on the areas you treat with fluorouracil unless your doctor tells you to.

Can you use Efudex on skin?

Apply only enough medicine to cover the affected skin with a thin film. Do not apply Efudex to skin that is irritated, peeling , or infected or on open wounds. Wait until these conditions have fully healed before using this medicine.

How long should I use Efudex cream?

When you are handed your tube of Efudex, also known as fluorouracil, the label will display your dermatologist’s instructions. They, too, are straightforward and printed according to your doctor’s recommendations. You may have been told to “apply a thin layer twice a day for 4 weeks.” In some cases, patients might be instructed to “apply cream once daily for 6-8 weeks.” This, unfortunately, is where things begin to get a little hazy. It seems no two patients are told exactly the same thing. It is certain that no two patients will experience the same pacing of results.

How to know if you are done with erosive cream?

You will know you have reached the erosion phase of treatment when your skin begins to crack open and weep clear fluid. Depending upon the patient, some areas may even bleed slightly once the cream has fully absorbed and the skin has dried out. At this point in treatment, it becomes extremely difficult to even apply the cream, and the slightest touch could send you into orbit. It is now you should make every effort to contact your prescribing physician and allow him/her to guide you in stopping or continuing a little longer. I was prescribed a 21-day course of treatment and reached erosion on day 17. A quick stop by my doctor’s office was enough to let me know I was indeed done and ready to begin healing.

Is Efudex cut and dry?

Your little bottle with the childproof cap even has an efficiently printed label clearly showing you when you need to stop taking your medication. Efudex, also a prescription medication, has the unfortunate distinction of not being so cut-and-dry.

How to treat a swollen face?

Only rinse your skin with water and pat dry. Don’t use your normal skin creams, lotions, or moisturizers. Avoid spraying cologne/perfume on the skin. Do not apply sunscreen - keep the area shielded from the sun. Efudex should be the only product applied to the area being treated. In the event you are treating your face, ...

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This article represents the opinions, thoughts, and experiences of the author; none of this content has been paid for by any advertiser. The SkinCancer.net team does not recommend or endorse any products or treatments discussed herein. Learn more about how we maintain editorial integrity here.

Is Efudex the only product applied to the area being treated?

Efudex should be the only product applied to the area being treated.

How long does it take for efudex to heal?

Healing after Efudex can be hard! You may, in fact, wonder if your skin will ever look normal again. While it takes some time, several weeks to a few months for most, your tender new skin will slowly return to normal.

How long does it take for your skin to heal after efudex?

Your skin may tend to be dry and flaky for several weeks once you start the healing after Efudex. Find a nice, mild moisturizer that won’t create an excess amount of oil on the skin. Don’t be surprised if you see a pimple or two pop up in the treated area during healing. I have noticed that my skin is much oilier while healing and moisturizing. I prefer Vanicream Lite Lotion to all others and use it several times throughout the day for several weeks following my last application of Efudex.

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