Treatment FAQ

how safe is radioactive iodine treatment

by Dr. Ona Littel IV Published 3 years ago Updated 2 years ago
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Radioactive iodine (RAI) is treatment for overactive thyroid
overactive thyroid
Hyperthyroidism, also called overactive thyroid, is a condition where your thyroid makes and releases high levels of thyroid hormone. This condition can make your metabolism speed up. Symptoms of hyperthyroidism include a rapid heartbeat, weight loss, increased appetite and anxiety.
https://my.clevelandclinic.org › health › 14129-hyperthyroidism
(hyperthyroidism) and certain types of thyroid cancer. The term “radioactive” may sound frightening, but it is a safe, generally well-tolerated, and reliable treatment that targets thyroid cells so there is little exposure to the rest of your body's cells.
Sep 8, 2020

What are the long term side effects of radioactive iodine?

Possible long term side effects include:Ability to have children (fertility) Some women may have irregular periods after radioactive iodine treatment. ... Inflammation of the salivary glands (where spit is made) ... Tiredness. ... Dry or watery eyes. ... Lower levels of blood cells. ... Lung problems. ... Second cancers.May 24, 2021

What are the risks of radioactive iodine treatment?

Risks and side effectsNeck tenderness and swelling.Nausea and vomiting.Swelling and tenderness of the salivary glands.Dry mouth.Taste changes.Mar 14, 2019

How successful is radioactive iodine treatment?

Conclusion: Radioactive iodine treatment is an effective modality for definitive treatment of hyperthyroidism with long-term cure approaching 80%.

Does radioactive iodine shorten your life?

Quality of life is worse at 6-10 years after radioactive iodine therapy of Graves' disease compared with treatment with antithyroid drugs or surgery. Quality of life is worse at 6-10 years after radioactive iodine therapy of Graves' disease compared with treatment with antithyroid drugs or surgery.

Can radioactive iodine cause other cancers?

Patients treated with radioactive iodine also have an increased risk of acute lymphocytic leukemia (ALL), stomach cancer, and salivary gland cancer.Jun 9, 2020

Can you refuse radioactive iodine treatment?

When patients refuse RAI therapy, the harm associated with no treatment (as in thyroid cancer) also must be weighed and communicated to the patients. In many cases of GD, for example, the use of antithyroid medications or surgical subtotal thyroidectomy may provide appropriate therapy without the use of RAI.

Where do you stay after radioactive iodine treatment?

To decrease the radiation dose to others:You should sleep in a separate bed. ... Remain in your home for the first four days.Do not hold young children or spend much time near a pregnant woman.Family members should stay about six feet or more from you.More items...•Apr 30, 2009

Which is better radioactive iodine or surgery?

Surgery for hyperthyroidism was associated with a lower risk of all-cause and cardiovascular death as compared to radioactive iodine therapy during long-term follow-up, particularly in men.

Does thyroid removal shorten life expectancy?

We have also shown that treatment per se (thyroidectomy, high-dose radioactive iodine and thyroid hormone medication) is safe and does not shorten life expectancy. Nonetheless, it remains important to realise that patients with persistent disease have a median standardised survival time of only 60%, independent of age.

Is there an alternative to radioactive iodine?

Alternative treatments include two major categories: redifferentiation therapy and molecular target therapy. Redifferentiation means reinduction of NIS expression and RI uptake. Several drugs that affect the epigenetic process of a cell have been investigated for redifferentiation therapy.

How long does it take to feel better after radioactive iodine?

The effect of this treatment on the thyroid gland usually takes between one and three months to develop. Maximum benefit occurs three to six months after treatment. Usually, a single dose is successful in treating hyperthyroidism.

Can thyroid come back after radioactive iodine treatment?

Once hypothyroidism has been achieved, it is usually irreversible with the patient requiring lifelong thyroid replacement. Early recurrences are reported in 20–54% of cases within 3–6 months, which can be due to inadequate RAI treatment or early Marine Lenhart syndrome.Sep 12, 2017

How to minimize radiation risks?

Keep Your Distance. Here are some ways to minimize radiation risks to other people (and pets) after you have had RAI treatment: Stay at least six feet away from other people, including members of the public, family members, and co-workers, for three to 11 days. This means avoiding public transportation, hotels, carpools, and in some cases, ...

How to avoid radiation?

Here are some ways to minimize radiation risks to other people (and pets) after you have had RAI treatment: 1 Stay at least six feet away from other people, including members of the public, family members, and co-workers, for three to 11 days. This means avoiding public transportation, hotels, carpools, and in some cases, your workplace. 2 Sleep apart from adults by at least six feet (a separate bedroom is recommended) and avoid sexual activity. 3 Avoid sleeping in the same bed with a pregnant woman, infant, or child for a period of six to 23 days. According to the Nuclear Regulatory Commission, infants and children should ideally stay outside the home for the recommended period. 1  4 To protect family pets, do not sleep with them for up to 21 days.

Does iodine affect thyroid?

Because the radioactive iodine used (known as iodine 131) may expose those around you to the effects of radiation (and theoretically negatively affect their thyroid glands), you will be given guidelines on how to prevent such exposure. Laura Porter / Verywell.

Can you hospitalize after a RAI?

It is not common in the United States to hospitalize patients after RAI, but if you are receiving a particularly high dosage of iodine 131 and have no way to protect children or babies, it may be an option. A Low-Iodine Diet Can Make Radioactive Iodine Treatment More Effective.

What is iodine used for?

Iodine, in the form of iodide, is made into two radioactive forms of iodine that are commonly used in patients with thyroid diseases: I-123 ( harmless to thyroid cells) and I-131 ( destroys thyroid cells ). The radiation emitted by each of these forms of iodine can be detected from outside the patient to gain information about thyroid function ...

Why is iodine important for the thyroid gland?

Iodine is essential for proper function of the thyroid gland, which use s it to make the thyroid hormones. The thyroid is equipped with an active system or “pump” for moving iodine into its cells, where it is concentrated as iodide. The thyroid gland is the only tissue in the body that takes up and holds onto iodine.

What is the I-123 isotope used for?

I-123 is the usual isotope used to take pictures and determine the activity of the intact thyroid gland ( Thyroid Scan and Radioactive Iodine Uptake, RAIU ), since it is harmless to thyroid cells. No special radiation precautions are necessary after a thyroid scan or RAIU using I-123. I-131 can also be used to take pictures of the thyroid gland, ...

What is the purpose of I-131?

THYROID CANCER – Large doses of I-131 are used to destroy thyroid cancer cells (see Thyroid Cancer brochure ). This is performed after the remaining thyroid cells ( including any cancer cells) are stimulated by raising TSH levels by either withdrawing the thyroid hormone pills or by treating with recombinant human TSH.

Is rai safe for X-rays?

RAI is safe to use in individuals who have had allergic reactions to seafood or X-ray contrast agents, since the reaction is to the compound containing io dine, not the iodine itself. RAI is given by mouth in pill or liquid form.

When can you stop breast feeding after I-131?

This protects the baby who would otherwise receive radioactive milk and the mother’s breasts which concentrate RAI. Breastfeeding must be stopped at least 6 weeks before administration of I-131 treatment and should not be restarted after administration of RAI, but can be safely done after future pregnancies.

Can RAI cause thyroid cancer?

Hypothyroidism is a common side effect of RAI for hyperthyroidism and always seen after RAI for thyroid cancer. This is usually easily treated with thyroid hormone replacement (see Hypothyroidism brochure ). Some studies suggest a slight increase in thyroid cancers may be seen after RAI treatment for hyperthyroidism.

What is the purpose of radioactive iodine?

The aim of the treatment is to damage and kill the cells responsible for the hyperthyroidism. Radioactive iodine and some other radioisotopes used in Nuclear Medicine are produced during the production of nuclear energy. They are a by-product or, if you like, a useful waste product.

Why is radio iodine so effective?

One of the reasons that radio-iodine treatment is so effective is because the thyroid readily takes up iodine, which is used in thyroid hormone production. To ensure that the treatment is maximised you will be asked to avoid any foods and medicines ...

How long do you have to stay in hospital after ablative thyroid?

Patients who have what is called an ablative dose (usually for treatment of thyroid cancer) are asked to stay in hospital for three days following the treatment. This is to reduce the doses to other members of the public.

How long does it take to stop taking anti-thyroid medication?

This is usually prescribed in the beginning, for all patients, and approximately half of all patients are successfully treated with this method and can cease taking the medication after six months.

Why can't you get pregnant after radiotherapy?

Patients are advised not to become pregnant for 6 months following radio-iodine treatment. This is because the radiation that is used could potentially affect the DNA in human cells.

What are the three types of radiation?

Nuclear Medicine concerns three types of radiation: Alpha particles, which are made up of two protons and two neutrons (the material that makes up the nucleus of any atom), Beta, which is either an electron or a positron (smaller particles that form part of an atom) and Gamma, which is basically an energy wave.

Where is I131 excreted?

I131 is excreted from the body in all bodily fluids, including urine and sweat, so it is best that the first few days (when the radiation present in the body is highest) are spent in isolation at the hospital where it matters less that things will become contaminated.

What Are The Side Effects Of Radioactive Iodine Treatment In Cats?

Injections do not cause any side effects. The procedure will not cause nausea, hair loss, lethargy, or a decrease in appetite for your cat. The thyroid levels of some cats may return to normal after treatment, however, and they may experience a short period of readjustment.

Does Radioactive Iodine Harm My Pets?

Even if your cats are in your lap, you will not be exposed to radioiodine therapy, so you can keep them around after you have been treated. While people sweat out the radioiodine, washing their hands regularly can remove the small amount of contamination on their hands very effectively.

How Long Do Cats Live After Radioactive Iodine Treatment?

The study Mosenco cited showed that cats treated with I-131 lived an average of four to five years after treatment, as opposed to cats on medication who only lived two years after treatment.

Can Iodine Hurt Cats?

The study found that cats with limited iodine intake did not experience any health problems. It is necessary for the researchers to conduct longer studies in order to prove that normal cats can live with diets containing iodine-deficient ingredients.

How Dangerous Are Cats After Radioactive Iodine Treatment?

The radioiodine therapy may also cause cats to vomit and diarrhea for 3-4 weeks after it has been administered, as the disease continues to resolve. Hyperthyroidism (8+ years) in cats can also lead to other diseases, which is why many of them are in their early twenties.

How Long To Stay Away From Pets After Radioactive Iodine?

If you are going to sleep with your pet for more than 21 days, do not do so.

Can You Be Around Dogs After Radioactive Iodine?

It is not necessary to worry about the effects on your family, pets, etc., but it is still prudent to avoid close, prolonged contact for the first week after the event.

Where does the thyroid take iodine?

This uptake happens in the stomach, lungs, even on skin.

How long can you stay in isolation after taking I131?

In fact, the USA is one of the ONLY countries that lets RAI patients go home after they take the I131. Most other countries keep RAI patients for 3-5 days in a special lead lined isolation room.

How long does I131 decay?

Interesting! I131 does has an 8 day half life (1), so for those of you who read our article on half life and decay know that every 8 days the amount of radiation becomes half. I recently read something that explained it in another way, the half life of an isotope “is really the lifetime of half of the isotope present in the system at any given time.” (2). If someone, even your doctor tells you that it (I131) will “evaporate” or “go away” in 16 days, he/she is dead wrong. Dangerous information like this scares me. Radiation can NEVER “just go away”, it will slowly decay until it becomes immeasurable! For the most part the rule of thumb is that once an isotope goes through 11 half lives, it is, for all practical purposes safe enough to be considered “not radioactive”. This, of course, depends on the starting activity level. All you will need to know is that any contamination that may be left in your home from the “discharge” of RAI treatment, will be safely decayed in 88 days.

Is I131 a beta particle?

People with healthily thyroids who uptake I131 may have dangerous beta particles mutating or killing their healthy cells. According to an article in the Journal of Clinical Endocrinology and Metabolism Exposure to small amounts if I131 may be more dangerous than large amounts.

How many half lives does an isotope have?

For the most part the rule of thumb is that once an isotope goes through 11 half lives, it is, for all practical purposes safe enough to be considered “not radioactive”. This, of course, depends on the starting activity level.

Is RAI safe for thyroid?

RAI treatment for Thyroid problems is an extremely effective and safe procedure for the patient! However exposing others to the radioactive contamination being eliminated from your body is a potential hazard. Over the many weeks of your therapy, your body will be releasing all of the I131 that was put into it.

Is the internet good or bad?

The good thing about the internet is that a tremendous amount of information is available to people 24 hours a day. The bad thing about the internet is that a lot of the information people are getting is very wrong. This is very true when it comes to radioactive iodine treatment. We have seen cases over and over where completely unqualified ...

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