Treatment FAQ

how painful is the surgery to insert the xen glaucoma treatment system?

by Prof. Shanel Larson Published 2 years ago Updated 2 years ago

Patients who undergo glaucoma surgery usually do not experience significant pain during or after the surgery. Like any surgery, many patients experience mild discomfort for a few weeks following surgery. Strong pain medication is not commonly needed. Most patients who undergo glaucoma surgery can achieve good pain relief with Tylenol.

Full Answer

What is Xen laser treatment for glaucoma?

Purpose: The purpose of this review is to summarize current knowledge on XEN implant for the treatment of glaucoma. Methods: A comprehensive literature review has been performed regarding XEN implant and its use on glaucoma management. Forty-two articles were checked and 37 were found to be relevant. Out of them, 21 were excluded as being case reports and …

What is Xen Gel Stent implantation?

Xen Gel Stent Implantation: A Glaucoma Surgery to Lower Eye Pressure. When glaucoma medicines and laser treatment fail or cannot be used to manage glaucoma, Xen is recommended for some patients. This surgery lowers the fluid pressure within the eye to lessen the likelihood of pressure damage to the optic nerve, which sends vision from the eye ...

Is the Xen® Gel Stent safe and effective in glaucoma?

INDICATIONS: The XEN ® Glaucoma Treatment System is available for the surgical management of refractory glaucomas, including cases where previous surgical treatment did not work, cases of primary open-angle glaucoma, and cases of pseudoexfoliative or pigmentary glaucoma with open angles that are unresponsive to maximum tolerated medical therapy.

How long will it take for my vision to improve after Xen?

Dec 18, 2018 · The XEN implant is a device which can be used to treat glaucoma, in cases where drops are not helping in the management, or when other types of surgery canno...

Is eye stent surgery painful?

You may see bright lights during the surgery, but should not feel any pain. You will be discharged with a clear plastic shield over the operated eye. An adult will need to drive you home since you received sedative medications.

Is glaucoma surgery painful?

Patients who undergo glaucoma surgery usually do not experience significant pain during or after the surgery. Like any surgery, many patients experience mild discomfort for a few weeks following surgery. Strong pain medication is not commonly needed.Jan 18, 2011

Is trabeculectomy surgery painful?

Your surgical site and stitches will be sore, but the soreness should improve once the stitches are removed. For the first two weeks after the procedure, you'll sleep with a protective shield over your eye while the surgical site heals to prevent it from being injured during the night.

What can I expect after Xen surgery?

The most common side effects after surgery include reduction of vision, eye pressure becoming too low, an increase in eye pressure, and need for an additional surgical procedure in the eye to release scar tissue (needling) around the implant under the conjunctiva. Talk to your doctor about other possible side effects.

Are you awake during glaucoma surgery?

The opening will be under your eyelid, where no one will see it. This opening allows extra fluid in your eye to drain away, lowering pressure in your eye. Usually, you'll be awake during this surgery — but you'll get numbing medicine and medicine to help you relax.Jan 3, 2022

Are you sedated for glaucoma surgery?

The different types of anesthesia for glaucoma surgery are general anesthesia, local anesthesia or topical anesthesia. In children, general anesthesia has an absolute indication, whatever the surgical procedure to be used.

How do you sleep after a trabeculectomy?

Our advice to patients following trabeculectomy is routine: no eye rubbing, and they need to wear the shield for at least one week post-surgery. If there's blood in the eye, I discourage any bending; the patient should sleep with extra pillows so the blood can settle inferiorly and then dissipate.Aug 5, 2013

Is trabeculectomy a major operation?

Trabeculectomy is a very delicate operation that requires an operating room, local anesthesia of the eye, an anesthesiologist, and about an hour of operating time. It is successful about 60-80 percent of the time in controlling the eye pressure during a period of five years.Jul 7, 2021

Do eye stitches hurt?

The procedure itself is not painful, but the operating light may appear very bright, and you will be aware of fluid washing over the eye, and most likely spilling down your cheek. Small tugging sensations can be expected as the sutures come out.

How long does Xen gel stent surgery take?

Expect to be at the surgery center for 2-3 hours. Properly caring for your eye after your procedure is important to the healing process. Keep the following instructions in mind: Please do not bend over at the waist for 1-2 days following your procedure.

What is the success rate of Xen gel stent?

The overall complete success rate was 21.0–70.8% after 2 years using strict criteria originally designed to record success rate in filtration surgery. The incidence of complications vision-threatening was low at <1%. Conclusions: XEN gel stent was effective and safe for primary and secondary OAG.Feb 4, 2022

How long is glaucoma surgery recovery?

Recovery time after glaucoma surgery varies per patient and per surgery, but most patients heal within 3 to 6 weeks. Reserve the day after the surgery for recovery time. During the rest of the recovery time, it's generally recommended that postoperative glaucoma patients avoid strenuous activity.Aug 10, 2018

Can you have cataract surgery before Xen?

Cataract surgery, if planned, may be performed before XEN implantation. Following intraocular lens (IOL) implantation, miotic drugs may be used to facilitate XEN implantation. The intended area of placement in the supero-nasal quadrant, which is 3 mm from the limbus, is marked.

What are the advantages of Xen implant?

Xen Implant has some advantages over traditional surgeries such as trabeculectomy and tube shunt surgeries: Soft and flexible when wet. Minimally invasive, pre-loaded injector. Shorter surgical and recovery times. Potentially fewer side effects, e.g. prevention of chronic hypotony by an intrinsic flow-limiting design.

Is glaucoma a risk factor for blindness?

Glaucoma is a leading cause of overall blindness, and the number one cause of irreversible blindness, both in the United States and worldwide. Elevated intraocular pressure (IOP) is a major risk factor for the development and progression of glaucoma.

Is IOP reduction good for glaucoma?

The decrease in quality of life associated with glaucoma can be profound and may occur earlier than previous thought, highlighting the importance of early diagnosis and treatment. Reduction of IOP is the only proven method to prevent and treat glaucoma.

What is Xen gel?

XEN GEL Implant (Allergan Inc., CA, USA) is a 6-mm hydrophilic tube of collagen-derived gelatin cross-linked with glutaraldehyde, which is non­inflammatory and causes minimal extraocular fibrotic or vascular response to the implant material. The XEN decreases IOP by creating a permanent drainage shunt from the anterior chamber (AC) to the subconjunctival space through a scleral channel. The device hydrates within 1-2 minutes of contact with aqueous humor, bending and conforming to tissue. This flexibility mitigates many of the issues seen with synthetic materials such as migration, erosion and corneal endothelial damage.

What is the best patient for Xen?

The most suitable patients for Xen implantation are: Patients with uncontrolled glaucoma, primary open-­angle glaucoma, and pseudoexfoliative or pigmentary glaucoma with open angles that are un responsive to maximum tolerated medical therapy.

Is Xen needling safe?

Prospective studies have reported needling rates as high as 46.2% within the first 12 months. XEN needling has been demonstrated to be relatively safe and effective. However, there are reports of XEN fractures and amputations caused by needling. One case series of XEN fractures after needling concluded that because XEN is composed of flexible gelatin, the device can be damaged relatively easily during the bleb needling process.

Does Xen help with glaucoma?

Although no surgery can cure glaucoma forever or reverse vision loss, Xen is an effective surgery that can slow or stop the progression of glaucoma by lowering the pressure in your eye. Xen is less invasive compared to traditional glaucoma surgery (trabeculectomy) and has a quicker recovery.

What happens when you have Xen?

Once the Xen has been implanted, fluid begins to leave the eye more easily. This escaping fluid raises the conjunctiva (clear membrane covering the white part of the eye) creating a “filtering bleb.”. This “bleb” or bubble on the surface of the eye is usually under the upper eyelid and not visible without raising the upper lid.

Can you reduce eye drops after glaucoma surgery?

Sometimes patients are able to reduce the number of eye drops they are taking. Even if you are taking the same glaucoma medications after the procedure, the surgery is a success if your pressure is lower.

How long does it take to return to work after eye surgery?

Depending on your job and your other eye, you should be able to return to work within a few days to a few weeks. Limitations in physical activities at work may be needed. After surgery, your eye may be sore, and it may feel like there is something in it, like an eyelash.

Where is the Xen placed?

The Xen is loaded in a specific inserter and is placed at the top part of the eye. One end is inside the eye and the other end is under the conjunctiva. So it drains the fluid form anterior part of the eye to the space under the conjunctiva.

Do you have to have follow up appointments for glaucoma?

It is very important that you keep your follow up appointments so your surgical team can monitor the pressure and the healing, watch for complications, and make sure that your eye stays on track for a positive result. The need for glaucoma eye drops is usually reduced if not eliminated after surgery.

Can you see bright lights during surgery?

You may see bright lights during the surgery, but should not feel any pain. You will be discharged with a clear plastic shield over the operated eye. An adult will need to drive you home since you received sedative medications.

What is Xen gel stent?

The XEN ® Gel Stent creates a small channel in the eye to drain fluid and help lower eye pressure. The XEN ® Gel Stent is tiny—about the length of an eyelash—and it’s placed just under the conjunctiva, which is a clear membrane that covers the white of your eye.

What happens after eye surgery?

The most common side effects after surgery include reduction of vision, eye pressure becoming too low, an increase in eye pressure, and need for an additional surgical procedure in the eye to release scar tissue (needling) around the implant under the conjunctiva. Talk to your doctor about other possible side effects.

How does a shunt help with glaucoma?

This is accomplished by creating a new opening for fluid to drain from the eye — or, by implanting a shunt to help drain the fluid. Although the surgery can lower eye pressure and help stabilize vision for a very long time, your doctors will still need to monitor your glaucoma during that time. Recovery from glaucoma surgery is usually a simple ...

How does glaucoma surgery help?

Glaucoma surgery is a procedure intended to reduce eye pressure in an effort to help stabilize vision and prevent future vision loss resulting from glaucoma. This is accomplished by creating a new opening for fluid to drain from the eye — or, by implanting a shunt to help drain the fluid.

Do you need a shield after glaucoma surgery?

“Some procedures do not require a shield.”. Most of the time, your eye drops schedule for your glaucoma will change after your procedure.

What is glaucoma surgery?

Glaucoma surgery is a procedure intended to reduce eye pressure in an effort to help stabilize vision and prevent future vision loss resulting from glaucoma. This is accomplished by creating a new opening for fluid to drain from the eye — or, by implanting a shunt to help drain the fluid.

Can glaucoma surgery help with vision?

Although the surgery can lower eye pressure and help stabilize vision for a very long time, your doctors will still need to monitor your glaucoma during that time. Recovery from glaucoma surgery is usually a simple and pain-free experience. Much depends on the type of procedure and your doctor’s expectations for the eye pressure recovery.

Who is the ophthalmologist at Wilmer Eye Institute?

Regardless, you will need to exercise some general precautions to assist with the healing process. Ophthalmologist E. Randy Craven, from the Wilmer Eye Institute, Johns Hopkins Medicine, provides essential information to keep in mind as you recover from your specific surgery.

Do eye drops hurt after glaucoma surgery?

Most of the time, your eye drops schedule for your glaucoma will change after your procedure. Depending on the surgery, your doctor may also prescribe new eye drops to hasten recovery. Most people who have glaucoma surgery do not experience significant pain. If you do feel pain in the eye, however, you should consult your eye doctor about ...

What is a shunt in glaucoma?

Glaucoma surgeries include the delicate, microscopic incisional trabeculectomy (with or without ExPRESS microshunt implantation), tube shunt implantation (a shunt is a glaucoma drainage device), and cyclophotocoagulation . There are also newer procedures called MIGS, or minimally invasive glaucoma surgery . Each type of glaucoma surgery has its unique uses, advantages and disadvantages.When considering glaucoma surgery, you should have a detailed discussion with your surgeon about the risks and benefits of the specific surgery you may undergo.

Does surgery slow the progression of glaucoma?

It’s important to note, however, that surgery has very high success rates in substantially slowing the progression of glaucoma. When it comes to surgical intervention for advanced glaucoma cases, the benefits typically outweigh the risks. The following are (rare) glaucoma surgery risks or side effects to discuss with your doctor: Vision loss.

What are the risks of glaucoma surgery?

As with any operation, there are risks associated with glaucoma surgery. This article discusses different risks so you can have an open dialogue with your eye surgeon (ophthalmologist). It’s important to note, however, that surgery has very high success rates in substantially slowing the progression of glaucoma. When it comes to surgical intervention for advanced glaucoma cases, the benefits typically outweigh the risks. The following are (rare) glaucoma surgery risks or side effects to discuss with your doctor: 1 Vision loss 2 Bleeding in the eye 3 Infection 4 Low eye pressure (or hypotony) 5 ScarringCataract formation

Is glaucoma surgery a risk?

When it comes to surgical intervention for advanced glaucoma cases, the benefits typically outweigh the risks. The following are (rare) glaucoma surgery risks or side effects to discuss with your doctor: Vision loss. Bleeding in the eye.

Can glaucoma surgery cause vision loss?

Vision Loss. In the short term after your operation, glaucoma surgery temporarily disrupts your vision. It is important to understand that permanent vision can be reduced, or even, in very rare instances, totally lost as a result of any of these glaucoma operations; however, vision loss is not a common permanent side effect.

Can cataracts be repaired with glaucoma?

Cataract formation most likely will be accelerated by glaucoma surgery, but luckily cataracts are fairly easy to fix surgically . Sometimes glaucoma surgeries are combined with cataract surgery if your ophthalmologist feels that the cataracts are having a moderate to significant impact on your vision. However, for some glaucoma surgeries it is better to perform the glaucoma surgery alone and address the cataract later in a second operation.

Is glaucoma permanent?

Although glaucoma surgery can prevent further vision loss and on rare occasions even improve vision, damage that has already occurred due to glaucoma is considered permanent and not yet reversible via medication, laser surgery, eye stents, or MIGS.

OVERVIEW

Surgical procedures for glaucoma have been evolving over the past 100 years. Over the past 25 years, we have made large strides in improving surgical techniques and outcomes. Glaucoma surgery is intended to lower the intraocular pressure (eye pressure.) By lowering the eye pressure, we attempt to slow down progression of the disease.

WHAT SHOULD I EXPECT FROM GLAUCOMA SURGERY?

Glaucoma surgery attempts to lower eye pressure by various methods. These methods will be clearly described in the following sections. Regardless of the method used, it must be clear to patients that it takes on average 3 to 6 weeks to recover from surgery.

IS THERE PAIN DURING OR AFTER GLAUCOMA SURGERY?

Patients who undergo glaucoma surgery usually do not experience significant pain during or after the surgery. Like any surgery, many patients experience mild discomfort for a few weeks following surgery. Strong pain medication is not commonly needed. Most patients who undergo glaucoma surgery can achieve good pain relief with Tylenol.

IS THERE BLURRY VISION AFTER GLAUCOMA SURGERY?

Patients may experience blurry vision for the first 3 to 6 weeks following surgery. The blurry vision can be very upsetting to patients who do not expect this. However, if the 3 to 6 week recovery period is clearly explained and emphasized to the patient, many patients do not have difficulty during this period.

WILL I NEED EYEDROPS AFTER GLAUCOMA SURGERY?

Most patients do not require “glaucoma” eye drops after surgery. They do, however, require three types of post-operative eye drops for the first 2 to 3 months following surgery. The types of drops needed include: 1. An antibiotic 2. An anti-inflammatory (usually prednisone) 3.

WHY DO WE PERFORM GLAUCOMA SURGERY?

Glaucoma surgery is an effective method of controlling the disease. The surgeries, however, DO NOT “cure” glaucoma. The goals of surgery are to lower the pressure so as to protect the optic nerve from continued damage. The surgeries do not restore sight which has already been lost. The surgeries do not improve vision.

WHAT TYPES OF GLAUCOMA SURGERY ARE THERE?

1. Trabeculectomy 2. Glaucoma Drainage Devices (Aqueous shunts) 3. Non-penetrating filtration procedures (Aqua Flow) 4. Diode laser cyclodrestruction

Can NSAIDs cause corneal perforation?

Use of topical NSAIDs may result in keratitis. In some susceptible patients, continued use of topical NSAIDs may result in epithelial breakdown, corneal thinning, corneal erosion, corneal ulceration, or corneal perforation. These events may be sight threatening.

What is the treatment for diabetic macular edema?

OZURDEX ® (dexamethasone intravitreal implant) is a corticosteroid indicated for the treatment of diabetic macular edema. OZURDEX ® is a corticosteroid indicated for the treatment of macular edema following branch retinal vein occlusion (BRVO) or central retinal vein occlusion (CRVO).

What is Xen 45?

INDICATIONS#N#The XEN ® Glaucoma Treatment System (XEN ® 45 Gel Stent preloaded into a XEN ® Injector) is indicated for the management of refractory glaucomas, including cases where previous surgical treatment has failed, cases of primary open-angle glaucoma, and pseudoexfoliative or pigmentary glaucoma with open angles that are unresponsive to maximum tolerated medical therapy.

Introduction

Patient Selection

  • Indications
    The Xen gel stent was approved by the FDA in 2016 for use in primary open ­angle glaucoma and pseudoexfoliative or pigmentary glaucoma with open angles that are unresponsive to maximum tolerated medical therapy, as well as refractory open angle glaucoma (OAG) that has failed previ…
  • Contraindications
    The Xen gel stent is generally contraindicated in patients with the following conditions: 1. Angle closure glaucoma, where the angle has not been surgically opened 2. Previous glaucoma shunt or valve 3. Conjunctival scarring or other pathology in the target quadrant 4. Active iris neovascular…
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Surgical Procedure

  • The Xen gel stent comes preloaded in an injector device, which is a sterilized, single-hand plastic inserter containing a 27-gauge sharp beveled needle.While ab externo approaches exist, the device is FDA-approved to be implanted ab interno, meaning from within the AC. The steps for each approach are described below.
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Perioperative Management

  • Pre-Operative
    1. Patients are instructed to stop all glaucoma medications on the day of the operation.
  • Post-Operative
    1. Patients are seen on postoperative day 1 and followed up at the physician's discretion. 2. Postoperative medication regimen varies, but generally includes topical antibiotic prophylaxis for 1 week and topical corticosteroids multiple times each day for at least one month followed by a …
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Complications

  • Most reported intra- and post-operative complications are minor and inherent to the surgical technique. However, more rare and serious complications have been reported. A critical point is the final placement of the Xen device.
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Outcomes

  • Efficacy and Safety Profile with Xen
    The Xen was introduced relatively recently, thus long-term results are yet to be published. Studies with 1-year follow-up have found it to be efficacious in lowering IOP significantly and reducing the number of hypotensive medications used, with minimal complications or serious side effects.M…
  • Ab Interno vs. Ab Externo Approaches
    Early studies comparing outcomes of ab interno and ab externo techniques report similar safety and efficacy profiles, including similar incidences of bleb revision and secondary surgery.The ab externo approach appears to be favored in the literature for its slightly greater IOP and glaucom…
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Conclusion

  • In the rapidly evolving era of less invasive glaucoma surgeries, Xen gel stent offers a new means of lowering IOP for patients with advanced open angle glaucoma. Most published studies are reporting early follow-up, so the long-term efficacy and safety are yet to be demonstrated. However, many trials with a 1-year follow-up have reported acceptable safety and good efficacy …
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