What is Ceprotin used to treat?
CEPROTIN is indicated for neonates, pediatric and adult patients with severe congenital Protein C deficiency for the prevention and treatment of venous thrombosis and purpura fulminans. 1
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What is the maximum injection rate for Ceprotin?
Administer Ceprotin at a maximum injection rate of 2 mL per minute except for children with a bodyweight of < 10 kg, where the injection rate should not exceed a rate of 0.2 mL/kg/minute.
What is Ceprotin [protein C concentrate (human) ]?
CEPROTIN [Protein C Concentrate (Human)] is indicated for neonates, pediatric and adult patients with severe congenital Protein C deficiency for the prevention and treatment of venous thrombosis and purpura fulminans. Please click for Full Prescribing Information. CEPROTIN [Protein C Concentrate (Human)] Prescribing information.
What is Ceprotin used for?
Ceprotin [protein C concentrate (human)] is made from human plasma and is used for patients with severe congenital Protein C deficiency for the prevention and treatment of venous thrombosis and purpura fulminans.
What is a protein C injection?
PROTEIN C CONCENTRATE is used to prevent and treat blood clots. It is used in patients who have low levels of protein C in their body. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. COMMON BRAND NAME(S): Ceprotin.
Is Protein C deficiency a blood disorder?
What is protein C deficiency? Protein C deficiency is a rare disorder that causes abnormal clotting of your blood. Protein C is one of many natural anticoagulants in blood that helps keep your clotting mechanism in check. An anticoagulant is a substance that prevents blood from clotting.
Can a doctor give you a protein shot?
This medication is given by injection into a vein as directed by your doctor. Dosage is based on your medical condition, age, weight, protein C level, and response to treatment. Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day.
What is the purpose of CEPROTIN?
CEPROTIN [Protein C Concentrate (Human)] is indicated for neonates, pediatric and adult patients with severe congenital Protein C deficiency for the prevention and treatment of venous thrombosis and purpura fulminans.
Is CEPROTIN anaphylactic shock?
In case of anaphylactic shock, the current medical standards for treatment are to be observed. Transmission of infectious agents: Because CEPROTIN is made from human plasma, it may carry a risk of transmitting infectious agents, e.g. viruses, the variant Creutzfeldt-Jakob disease (vCJD) agent, and theoretically, ...
Does ceprotin contain heparin?
Warnings and Precautions. Hypersensivity: CEPROTIN may contain trace amounts of mouse protein and/or heparin as a result of the manufacturing process. Allergic reactions to mouse protein and/or heparin cannot be ruled out. If symptoms of hypersensitivity/allergic reaction occur, discontinue the injection/infusion.
How long does it take for ceprotin to heal?
Treatment with Ceprotin healed non-necrotic skin lesions after a median of four days, and necrotic skin lesions were healed after a median of 11 days. Seven patients took Ceprotin as a preventive measure before surgery or anticoagulation therapy and had no associated blood clotting complications.
How many strengths does ceprotin have?
Ceprotin comes in the following strengths: One package of Ceprotin contains one vial of Ceprotin powder, one vial of Sterile Water for Injection (diluent), one double-ended transfer needle, one filter needle, one full prescribing physician insert and one patient package insert.
How to clean ceprotin stoppers?
Wash your hands and put on clean exam gloves (optional). Remove caps from the Ceprotin and diluent vial to expose the centers of the rubber stoppers. Cleanse the stoppers with an alcohol swab (or other suitable solution suggested by your doctor) by rubbing the stoppers firmly for several seconds and allow them to dry.
What is the first FDA approved treatment for congenital protein C deficiency?
Ceprotin is the first FDA approved therapy for patients with severe congenital Protein C deficiency. It is indicated for patients with severe congenital Protein C deficiency for the prevention and treatment of venous thrombosis and purpura fulminans (PF) (a severe skin and systematic blood clotting disorder).
What is the purpose of ceprotin?
Ceprotin [Protein C Concentrate (Human)] is indicated for patients with severe congenital Protein C deficiency for the prevention and treatment of venous thrombosis and purpura fulminans . Ceprotin is indicated as a replacement therapy for pediatric and adult patients.
What are the most common adverse reactions to Ceprotin?
The most serious and common adverse reactions observed in clinical trials were rash, itching and lightheadedness. The following adverse reactions have been identified during postapproval use of Ceprotin: hemothorax, hypotension, hyperhydrosis, fever and restlessness.
Is ceprotin a protein?
Ceprotin approved by FDA. The U.S. Food and Drug Administration (FDA) has approved Ceprot in [Protein C Concentrate (Human)], a plasma-derived Protein C concentrate for use as replacement therapy in patients with life-threatening blood-clotting complications related to severe congenital Protein C deficiency.
