Your doctor will give you your injection of 1 to 2 mL EUFLEXXA (20 mg/ 2 mL) into your affected knee joint or other synovial joints once a week, for a total of three injections. If symptoms persist see your doctor. If you have any questions or problems, talk to your doctor.
Full Answer
What is in each mL of euflexxa?
injection of EUFLEXXA; Most people experience significant relief after the third (last) injection; For maximum pain relief, be sure to get all 3 injections; When it comes to duration of pain relief, each person is different. In general, 1 course of 3 EUFLEXXA injections has been shown to provide up to 6 months of knee relief
How is euflexxa administered?
· Adult Dosage: Prior to treatment: remove joint effusion (use separate syringe), if present. Inject 2mL (full syringe contents) intra-articularly in each affected knee weekly for 3 …
How long does euflexxa last?
· INDICATIONS. EUFLEXXA (1% sodium hyaluronate) is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics (e.g., acetaminophen).. DOSAGE AND ADMINISTRATION Directions for Use. Each package of EUFLEXXA is manufactured using …
What is euflexxa 1% sodium hyaluronate?
· Physician reviewed Euflexxa injection (injection) patient information - includes Euflexxa injection description, dosage and directions. ... diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 3 May 2022), Cerner Multum™ (updated 28 Apr 2022), ASHP (updated 11 Apr 2022) and others.
How many EUFLEXXA injections are in a series?
The Euflexxa injections can be performed every 6 months, and typically provide our patients with approximately 6 months of relief. The Euflexxa injections are a series of 3 injections performed over 3 weeks. Ideally, injections should be obtained 7-10 days apart for optimal outcomes.
Is EUFLEXXA a one time injection?
Euflexxa is injected directly into your knee joint. A healthcare provider will give you this injection. Euflexxa is usually given once every week for 3 to 5 weeks.
How often do you inject EUFLEXXA?
Your doctor will give you your injection of EUFLEXXA (20 mg/ 2 ml) into your knee joint once a week, for a total of three injections.
How many mg are in EUFLEXXA?
ImagesBRANDFORM.Gelsyn-3 intra-articular -16.8 mg/2 mL solutionORTHOVISC intra-articular -30 mg/2 mL solutionHyalgan intra-articular -10 mg/mL solutionEUFLEXXA intra-articular -10 mg/mL(mw 2.4 -3.6 million) solution1 more row
What is the strength of EUFLEXXA?
EUFLEXXA (1% sodium hyaluronate) is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics (e.g., acetaminophen).
How much does an injection of EUFLEXXA cost?
While Euflexxa is may be less costly than other brands of viscosupplementation, it is still expensive, retailing at around $5,000 for the three-shot series. Therefore, it may be out of reach for even insured individuals who have a high copay or coinsurance costs.
Does EUFLEXXA work on bone on bone?
“I've had 3 series of Euflexxa with good relief from bone on bone pain as long as I don't overdo. They make it easier to walk and reduce general pain and stiffness. They also help significulty with preventing my knee from going into a sublux position.
Is EUFLEXXA better than Synvisc?
Both Euflexxa and Synvisc consist of a three-injection treatment course. However, Synvisc One only requires one injection. Both Euflexxa and Synvisc are effective at treating the pain and decreased mobility that accompany knee osteoarthritis.
Can EUFLEXXA make knee pain worse?
Also, after the injection, you may experience increased pain and swelling in the knee at first. If the pain or swelling continues or worsens, talk to your doctor promptly. It is important to have this medication injected on schedule. It may take up to 3 injections before the full benefits of this medication occur.
How often can gel-one injections be given?
Gel-One is usually given once every week for 3 to 5 weeks. Follow your doctor's dosing instructions very carefully. To prevent pain and swelling, your doctor may recommend resting your knee or applying ice for a short time after your injection.
How do you bill for EUFLEXXA injections?
When this injection is administered either unilaterally or bilaterally the injections would be billed by placing J7325 in item 24 (FAO-09 electronically) and listing the total number of mg's administered in the units field.
Is EUFLEXXA made from rooster combs?
There are five forms on the market right now: Synvisc, Orthovisc, Hyalgan, Supartz, and Euflexxa. All of these products utilize either avian (bird) HA/purification or an avian gene to code HA production, except Euflexxa. It appears that Euflexxa is the only completely human or non-avian product.
Before Taking This Medicine
You should not receive Euflexxa if you are allergic to it, or if you have an infection in your knee or in the skin around your knee.Euflexxa is not...
What Happens If I Overdose?
Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
What Should I Avoid After Receiving Euflexxa?
For at least 48 hours after your injection, avoid jogging, strenuous activity, or high-impact sports such as soccer or tennis. Also avoid weight-be...
What Other Drugs Will Affect Euflexxa?
Other drugs may affect Euflexxa, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all y...
What Do I Need to Tell My Doctor Before I Take Euflexxa?
1. If you have an allergy to hyaluronic acid or any other part of Euflexxa (hyaluronate and derivatives injection (knee)). 2. If you are allergic t...
What Are Some Things I Need to Know Or Do While I Take Euflexxa?
1. Tell all of your health care providers that you take Euflexxa (hyaluronate and derivatives injection (knee)). This includes your doctors, nurses...
How Is This Medicine (Euflexxa) Best Taken?
Use Euflexxa (hyaluronate and derivatives injection (knee)) as ordered by your doctor. Read all information given to you. Follow all instructions c...
What Are Some Side Effects That I Need to Call My Doctor About Right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor o...
What Are Some Other Side Effects of Euflexxa?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help i...
How Do I Store and/or Throw Out Euflexxa?
1. If you need to store Euflexxa (hyaluronate and derivatives injection (knee)) at home, talk with your doctor, nurse, or pharmacist about how to s...
Indications for: EUFLEXXA
Osteoarthritis of the knee in patients who have failed nonpharmacologic therapy and analgesics (eg, acetaminophen).
Adult Dosage
Prior to treatment: remove joint effusion (use separate syringe), if present. Inject 2mL (full syringe contents) intra-articularly in each affected knee weekly for 3 weeks. Use separate syringes for each knee.
EUFLEXXA Interactions
Avoid disinfectants with quaternary ammonium salts. Concomitant other intra-articular injectables: not recommended.
Adverse Reactions
Arthralgia, increase blood pressure, inj site pain, local reactions, transient knee inflammation.
Can pregnant women take EUflexxa?
Pregnancy: The safety and effectiveness of EUFLEXXA have not been established in pregnant women.
Is intra articular injection safe?
Safety and effectiveness of injection in conjunction with other intra-articular injectables, or into joints other than the knee has not been established.
Why not inject intravascularly?
Do not inject intravascularly because intravascular injection may cause systemic adverse events.
How many adverse events were reported in the EUflexxa study?
A total of 119 patients reported 196 adverse events; this number represents 54 (33.8%) of the EUFLEXXA group and 65 (44.4%) of the active control group. There were no deaths reported during the study. Incidences of each event were similar for both groups, except for knee joint effusion, which was reported by 9 patients in the active control group and one patient in the EUFLEXXA treatment group. Fifty-two adverse events were considered device-related. Table 1 lists the adverse events reported during this investigation.
How many centers were involved in the EUflexxa study?
This clinical investigation was a prospective randomized, double-blinded, active control (commercially available hyaluronan product) study conducted at 10 centers. Three hundred twenty-one patients were randomized into groups of equal size to receive either EUFLEXXA (n=160) or the active control (n=161).
How long is EUflexxa trial?
Adverse event information regarding the use of EUFLEXXA as a treatment for pain in OA of the knee was available from two sources; a 12 week multicenter clinical trial conducted in Germany, and a 26 week multicenter clinical trial conducted in the US.
How to store EUflexxa?
Do not use EUFLEXXA if the package is open or damaged. Store in original package at 2°-25°C (36°-77°F). Protect from light. Do not freeze.
Where is Euflexxa injected?
Euflexxa is injected directly into your knee joint. A healthcare provider will give you this injection.
When is Euflexxa given?
Euflexxa is usually given when other arthritis medications have not been effective.
What to do if you miss an appointment for Euflexxa?
Call your doctor for instructions if you miss an appointment for your Euflexxa.
Can Euflexxa harm a baby?
blood clots or circulation problems in your legs; or. an allergy to birds, feathers, or egg products. It is not known whether Euflexxa will harm an unborn baby. Tell your doctor if you are pregnant. It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.
Can you take Euflexxa if you are allergic to it?
Before taking this medicine. You should not receive Euflexxa if you are allergic to it , or if you have an infection in your knee or in the skin around your knee. Euflexxa is not approved for use by anyone younger than 21 years old. Tell your doctor if you have ever had:
What is Euflexxa fluid?
Euflexxa is similar to the fluid that surrounds the joints in your body. This fluid acts as a lubricant and shock absorber for the joints.
What are the side effects of Euflexxa?
Euflexxa side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. severe pain or swelling around the knee after the injection. warmth, pain, redness, stiffness, bruising, or puffiness where the medicine was injected;
How long after Euflexxa can you stand on your feet?
Do not stand on your feet for more than 1 hour at a time during the first 48 hours after getting Euflexxa (hyaluronate and derivatives injection (knee)). Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
Can Euflexxa cause side effects?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Irritation where Euflexxa (hyaluronate and derivatives injection (knee)) is used.
Can you be allergic to Euflexxa?
If you are allergic to Euflexxa ( hyaluronate and derivatives injection (knee)); any part of Euflexxa (hyaluronate and derivatives injection (knee)); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
Can you take Euflexxa with OTC?
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Euflexxa (hyaluronate and derivatives injection (knee)) with all of your drugs and health problems.
Can Euflexxa cause bruising?
Side effects associated with Euflexxa injection are often mild and self-limiting. Post-injection reactions such as swelling, redness, and bruising can be minimised by applying ice pack on the treated joint. Although rare, hypersensitivity reactions may still occur. The injector and patient must watch out for symptoms of itching, rash, nausea, and difficulty of breathing.
Does Euflexxa help with joint pain?
Euflexxa can relieve joint pain by lubricating the joints, allowing greater mobility and flexibility, thereby reducing pain in the affected joint.
Can hyaluronic acid be used for arthritis?
In the United States, intra-articular injection of hyaluronic acid is only approved for knee arthritis, but in other parts of the world, it is approved for other types of painful joint arthritis.
What is Euflexxa made of?
Euflexxa is an injectable made of sodium hyaluronate or hyaluronic acid (HA), which is indicated for the treatment of pain associated with knee osteoarthritis (OA). Patients who have failed to experience adequate relief from simple pain relievers and non-pharmacologic therapy are good candidates for this treatment. The safety profile of Euflexxa has been established for up to 1 year.
