Treatment FAQ

how many pt with chronic hep b possitve has hbsag negative with treatment of vemlidy

by Ms. Lura Mohr Published 2 years ago Updated 1 year ago

Does Vemlidy cure hepatitis B?

Vemlidy is a prescription antiviral medicine that prevents the hepatitis B virus from multiplying in your body. Vemlidy is used to treat patients with chronic hepatitis B infection in adults with compensated liver disease. Vemlidy may lower the amount of HBV in your body and may improve the condition of your liver.

Can HBsAg become negative after treatment?

Patients who become HBsAg negative and develop antibody to HBsAg (anti-HBs) are diagnosed as having resolved hepatitis B [3,4]. This is an uncommon phenomenon in chronic HBV infection. During stage HBV DNA may still be detectable by PCR in serum and more often in the liver.

Which is the initial treatment recommended for chronic hepatitis B?

Treatment for chronic hepatitis B may include: Antiviral medications. Several antiviral medications — including entecavir (Baraclude), tenofovir (Viread), lamivudine (Epivir), adefovir (Hepsera) and telbivudine (Tyzeka) — can help fight the virus and slow its ability to damage your liver.

Can tenofovir cure chronic hepatitis B?

Tenofovir will not cure hepatitis B and may not prevent complications of chronic hepatitis B such as cirrhosis of the liver or liver cancer. Tenofovir may not prevent the spread of hepatitis B to other people.

Can chronic hepatitis B be cured totally?

Infants and children are more likely to develop a chronic (long-lasting) hepatitis B infection. A vaccine can prevent hepatitis B, but there's no cure if you have the condition. If you're infected, taking certain precautions can help prevent spreading the virus to others.

How long can a person with chronic hepatitis B live?

The estimated carrier life expectancy is 71.8 years, as compared to 76.2 years among noncarriers (Figure ​ 5). These results are consistent with other estimates, which indicate that 15% to 40% of HBV carriers die of liver complications.

How long can tenofovir cure hepatitis B?

Tenofovir continues to suppress hepatitis B virus for eight years.

When is chronic hepatitis B treated?

Treatment is generally indicated in chronic hepatitis B patients with HBV DNA >2000 IU/mL, elevated ALT and/or at least moderate histological lesions, while all patients with cirrhosis and detectable HBV DNA should be treated.

What is chronic active hepatitis B?

People who test positive for the hepatitis B virus for more than six months (after their first blood test result) are diagnosed as having a chronic infection. This means their immune system was not able to get rid of the hepatitis B virus and it still remains in their blood and liver.

When can you stop taking Vemlidy?

You must take VEMLIDY exactly how your doctor tells you to. Do not stop taking VEMLIDY unless your doctor tells you to. If you stop taking your medicine, your HBV infection could get worse (flare-up). A “flare-up” is when your HBV infection suddenly returns in a worse way than before.

How long should one take tenofovir?

Treatment for HIV is usually lifelong. Continue to take tenofovir regularly for as long as your doctor tells you to, even if you feel well. This is to keep your immune system healthy.

What is the new treatment for hepatitis B?

A consortium of leading virologists, immunologists and physicians specialized in treating viral hepatitis, will use a newly designed therapeutic vaccine, TherVacB, as an immunotherapy to cure HBV. TherVacB will be evaluated in a three-year clinical trial starting in 2022 conducted in Europe and in Africa.

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