
How to treat tuberculosis (TB) during pregnancy?
TB Treatment & Pregnancy 1 TB Treatment Regimens for Pregnant Women. The preferred initial treatment regimen is INH, rifampin (RIF), and ethambutol (EMB) daily for 2 months, followed by INH and RIF daily, or twice ... 2 Contraindications 3 Drug-Resistant TB. ...
Is tuberculin skin test safe during pregnancy?
1 Introduction. Untreated tuberculosis (TB) disease represents a greater hazard to a pregnant woman and her fetus than does its treatment. 2 Testing. The tuberculin skin test is considered both valid and safe to use throughout pregnancy. ... 3 Treatment. ... 4 Contraindications. ... 5 Breastfeeding. ...
How long after chemotherapy can you get pregnant?
You should wait at least 1 year after completing chemotherapy before trying to get pregnant so your body has time to clear out any damaged eggs. Chemotherapy and some other cancer treatments can harm a growing embryo or fetus. If you become pregnant while on one of these treatments, you may have a miscarriage or your child may have birth defects.
When should treatment of tuberculosis (TB) be initiated?
Treatment should be initiated whenever the probability of TB is moderate to high. Infants born to women with untreated TB may be of lower birth weight than those born to women without TB and, in rare circumstances, the infant may be born with TB.

Can I get pregnant after tuberculosis treatment?
After completion of treatment for latent TB, infertile women had nearly 52% successful pregnancy compared with 40.5% in the case of infertile women who did not have latent TB. Latent TB treatment did improve the chances of pregnancy.
Can TB patient can conceive?
Two out of 10 women suffering from TB cannot bear children, but experts say that with advanced medical treatment now available, if the diagnosis is early enough, GTB can be treated and the woman can regain fertility. “Kala was treated for nine months for tuberculosis.
Does TB affect future pregnancy?
M. tuberculosis affects the female genital organs, especially the fallopian tubes, and thereby causes infertility. It can occur in any age group, but women in the reproductive age group (15-45 yr) are the most affected18.
Can TB drugs cause infertility?
TB patients have to take not less than 4 anti-TB drugs simultaneously for a long time and anti-TB drugs negatively influence on sexual function too. It is necessary to have high index of suspicion for in-time diagnosis of genital TB, because infertility may be a first symptom of this disease.
Can I get married after TB treatment?
Finally, treatment of TB requires a 6-month or more course of drug therapy and participants generally considered it preferable to delay marriage until the course has been completed.
Are anti TB drugs safe for pregnancy?
All 4 first line drugs [isoniazid, rifampicin (rifampin), ethambutol and pyrazinamide] have an excellent safety record in pregnancy and are not associated with human fetal malformations.
Does TB affect uterus?
Uterine (endometrial) factors Genital TB affects endometrial receptivity leading to defective endometrial markers and vascularization of the endometrium, and endometrial atrophy and synechiae formation26.
How does tuberculosis affect the reproductive system?
This disease is an important cause of infertility, menstrual irregularity, pregnancy loss, and in association with pregnancy, morbidity to both the mother and child increases. Some of the effects of TB infection on female genital tract could be remote in nature due to infection elsewhere.
Can TB cause lower birth weight?
Infants born to women with untreated TB may be of lower birth weight than those born to women without TB and, in rare circumstances, the infant may be born with TB. Although the drugs used in the initial treatment regimen for TB cross the placenta, they do not appear to have harmful effects on the fetus.
Is TB a hazard to pregnant women?
Untreated tuberculosis (TB) disease represent s a greater hazard to a pregnant woman and her fetus than does its treatment. Treatment should be initiated whenever the probability of TB is moderate to high. Infants born to women with untreated TB may be of lower birth weight than those born to women without TB and, in rare circumstances, ...
Can pregnant women take rifapentine?
TB Treatment Regimens for Pregnant Women. The 3-month weekly INH and rifapentine (3HP) regimen is not recommended for pregnant women or women expecting to become pregnant during the treatment period because its safety during pregnancy has not been studied. The preferred initial treatment regimen is INH, rifampin (RIF), ...
Can breast milk cause TB?
For the same reason, drugs in breast milk are not an effective treatment for TB disease or latent TB infection in a nursing infant. Breastfeeding women taking INH should also take pyridoxine (vitamin B6) supplementation. RIF can cause orange discoloration of body fluids, including breast milk.
Can TB be delayed during pregnancy?
For women who are at high risk for progression from latent TB infection to TB disease, especially those who are a recent contact of someone with infectious TB disease, treatment for latent TB infection should not be delayed on the basis of pregnancy alone, even during the first tri mester.
Is pyridoxine a 6 month regimen?
6- or 9-month daily regimen of INH (6H or 9H) , with pyridoxine (vitamin B6) supplementation. The 3-month weekly INH and rifapentine (3HP) regimen is not recommended for pregnant women or women expecting to become pregnant during the treatment period because its safety during pregnancy has not been studied. TB Disease.
How long does it take for an egg to be released after a LH surge?
Usually an egg is then released from the ovary within 24-32 hours after the surge (ovulation). Ovulation predictor kits should be started cycle day 11, testing twice daily approximately 12 hours apart. When an LH surge is detected, intercourse or insemination should occur within 12 to 24 hours after the surge.
When is the peak response for clomiphene?
Patients who receive clomiphene from cycle day 2 through 6 can expect the peak response around cycle day 12 of treatment. Therefore ultrasound examinations are performed at about this time and the follicles are expected to be 20 to 24 mm. In mean diameter. HCG has an action similar to that of LH.
Is it dangerous to have a tubal ligation reversal?
A primary concern is the risk of ectopic [tubular] pregnancy – it is greater after tubal ligation reversal than if your tubes had never been tied. Ectopic pregnancies can be dangerous, even rarely fatal, but that is not why we are so concerned.
When should TB be treated during pregnancy?
Strong consideration should be given to treatment of high-risk individuals with latent TB infection during pregnancy; if treatment is not initiated during pregnancy, it should be started within 2–3 months postpartum.
What is the role of a gynecologist in TB?
Obstetrician–gynecologists may consult and collaborate with disease experts, including infectious disease specialists, TB control programs, TB medical consultants, and health departments, to ensure timely and accurate diagnosis, linkage to care, and treatment compliance. Acknowledgments.
How do tuberculosis spread?
If alive, these bacilli may spread by way of lymphatic channels or through the bloodstream to more distant tissues and organs. The tubercle bacilli may reach any part of the body, including areas where active TB disease is more likely to develop (such as the brain, larynx, lymph node, lung, spine, bone, or kidney).
What are the symptoms of TB?
Symptoms of active TB disease include loss of appetite, weight loss, fever, night sweats, chills, and weakness. Pulmonary TB symptoms also include cough, chest pain, and hemoptysis. The clinical presentation reflects the organ system that is involved in disease.
What is TB evaluation?
A TB evaluation consist s of a TB risk assessment, medical history, physical examination, and a symptom screen; a TB test should be performed if indicated by the TB evaluation.
Why is screening important for TB?
Screening individuals at risk for TB infection or at risk for progressing to active TB disease and ensuring proper treatment are important to reduce complications of the disease and are critical to efforts to control TB in the United States.
Do TB patients have latent TB?
While the bacilli are sequestered, individuals will usually have no signs or symptoms of TB; they have latent TB infection. Most people with a TB infection have latent TB infection and never experience any manifestations of their infection, that is, they never progress to active TB disease.
What are the complications of being pregnant?
Complications. Breastfeeding. When you’re pregnant, your doctor will give you a number of routine tests to check for any health issues that might pose problems for you or your baby. One thing they may check you for early on is tuberculosis (TB). It’s a contagious bacterial disease that usually affects your lungs.
Can TB be fatal?
It’s a contagious bacterial disease that usually affects your lungs. If you don’t get the right treatment for TB, it can be dangerous for you and your baby. You can die of it. So your doctor will want you to start treatment right away.
Can TB cause birth defects?
Some TB drugs can lead to birth defects or other problems in a growing baby. But your doctor won’t prescribe those drugs if you’re pregnant or thinking about getting pregnant. The medicine you get will depend on what kind of TB you have. Latent TB.
Can you take isoniazid while pregnant?
For the rest of your pregnancy, it’s likely that you’ll take only isoniazid and rifampin, either daily or twice a week. HIV and TB. If you also have HIV, your doctor probably will give you the same drugs to treat both diseases that they would give someone who’s not pregnant.
Can tuberculosis be treated while pregnant?
It’s much worse to leave it untreated. TB drugs you take do reach your baby. But they haven’t been shown to cause harm in unborn babies.
Can you have TB and not know it?
You can have TB and not know it. That’s called latent TB. But if you have active TB, you’ll have symptoms like coughing for weeks, weight loss, bloody phlegm, and night sweats. The active form of the disease is more serious. But both active and latent TB can cause harm to your baby. They may be more likely to:
Can you take TB drugs while pregnant?
Your doctor may recommend that you switch to so-called second-line drugs. Some of them aren’t safe to take during pregnancy. They can cause birth defects and other problems.
How long after chemo can you get pregnant?
You should wait at least 1 year after completing chemotherapy before trying to get pregnant so your body has time to clear out any damaged eggs. Chemotherapy and some other cancer treatments can harm a growing embryo or fetus.
How long do you need endocrine therapy?
You will need endocrine therapy for 5 to 10 years. We don’t know if interrupting endocrine therapy to try to get pregnant will lessen its effect. The decision to interrupt therapy to try to get pregnant is a personal one. Talk with your healthcare team to decide what’s right for you.
Can you get pregnant after breast cancer treatment?
But, women who get pregnant after treatment for breast cancer don’t have a higher risk of recurrence or death from breast cancer.
Can you stop birth control after breastfeeding?
This is to clear the medication from your body. If you do interrupt endocrine therapy, we recommend you restart it after your child is born or after you stop breastfeeding. Use birth control to keep from getting pregnant until you talk with your healthcare team to come up with a plan that works for you.
Can you use frozen eggs to get pregnant?
If your egg supply is low, you may have more success if you use your frozen eggs or embryos. If you’re interrupting treatment with endocrine therapy, it’s important to limit your time off of treatment. In this case, you may want to use your frozen eggs or embryos instead of trying to become pregnant naturally.
Can you get pregnant after a pregnancy?
If you finished your treatment, you can try to get pregnant naturally if you want to. If you don’t get pregnant after 3 to 4 months of trying, you may want to be evaluated by your reproductive endocrinologist (fertility specialist). If your egg supply is low, you may have more success if you use your frozen eggs or embryos.
Can chemotherapy affect your future child?
The medications you took during your treatment need to be cleared from your body. The medications you took may affect the health of your future child. There are 2 things to keep in mind: Chemotherapy can cause genetic mutations (changes in genes) in some of your eggs.
How long after LLETZ can you get pregnant?
On average, pregnancy should be avoided for a minimum of eight weeks after LLETZ. The infected area is removed in the surgery.
How long does it take for cervix to heal?
Although the abnormal cells grow very slowly, they can develop into cancerous cells. So, treatment is required for it. It is found cervix heal within six weeks. But some women have healed quickly within three weeks.
How long does pelvic pain last?
The pelvic pain, which is the common side effect, lasts over a couple of days to around two weeks, but this is a clear indication of recovery. For most of the patients, it settles down nearly on the third day of post-treatment. The pain reaches the peak in one to two days of the procedure and starts to subside thereby.
Is cervix surgery a long process?
The surgery is minor, but the after recovery can be a lengthy process. When the cells are removed from the cervix, they are further sent in the lab to check if it contains any cancerous properties. The patient might have cancer, and it is identified in the surgery. If the cancer is detected, the process is treated to tackle cancer ...
Does Lletz cause vaginal bleeding?
Finally, it can be concluded that LLETZ prevents the development of cells into cancer in the cervix. After the operation, you can suffer from pain, bleeding of the vagina, and a change in the discharge from the vagina. But this ends within a few days or weeks. There are no risks after treatment with LLETZ for women who are concerned about getting ...
How long after radioactive iodine therapy can you have an abortion?
In the radioactive iodine therapy group, there was an about 4 times higher risk of abortion if a woman became pregnant before 6 months after treatment compared to 12-23 months after treatment. Women’s age over 35 years at pregnancy was also associated with a higher risk of abortion.
How old is the average thyroidectomy?
The average age at thyroidectomy or radioactive iodine therapy was 39.8 years in the whole group. A total of 10,842 (9.7%) women became pregnant after treatment (9.4% in the radioactive iodine therapy and 10% in the surgery group).
What is thyroidectomy surgery?
Thyroidectomy: surgery to remove the entire thyroid gland. When the entire thyroid is removed it is termed a total thyroidectomy. When less is removed, such as in removal of a lobe, it is termed a partial thyroidectomy. Radioactive iodine (RAI): this plays a valuable role in diagnosing and treating thyroid problems since it is taken up only by ...
What is the term for a baby born before 38 weeks?
Premature delivery: birth of a baby before 38 weeks of pregnancy. Miscarriage (spontaneous abortion): this occurs when a baby dies in the first few months of a pregnancy, usually before 22 weeks of pregnancy. Thyroidectomy: surgery to remove the entire thyroid gland. When the entire thyroid is removed it is termed a total thyroidectomy.
How long does it take to get pregnant?
It can take a couple up to a year to get pregnant, even with no problems related to their reproductive respective health. 2 Still, going several cycles without conceiving often concerns women about the state of their fertility, especially after they've stopped birth control.
How long does it take for a woman to ovulate after stopping the pill?
Most women begin to ovulate again within two weeks of stopping the pill, which is a sign that you are now able to get pregnant again. While you have a chance to get pregnant during every ovulation cycle, you still may not get pregnant right away.
What do doctors do when pregnant?
Doctors often advise women to have a preconception health visit with their doctor or midwife if they are thinking about getting pregnant. Your provider can help you devise a plan and ensure you are as healthy as possible in preparation for pregnancy.
When do women use oral contraceptives?
Other Precautions. Many women use oral contraceptives or "the pill" as their method of contraception when they're trying to prevent pregnancy. If you're among this group, then the first step when you decide you are ready to start trying to conceive will be getting off the pill.
Is withdrawal bleeding the same as menstrual bleeding?
Withdrawal bleeding is not the same as true menstrual bleeding, but that doesn't mean you aren't fertile. If you do get pregnant before having your first true post-pill period, you may have a slightly harder time pinpointing exactly when you ovulated, which could make it challenging to estimate your due date .
Can you get pregnant right away?
Doctors also once believed that if you got pregnant right away, there was a higher chance of miscarriage. It turns out that isn't true, as the hormones found in birth control pills don't stay in your system after you stop taking them. 1 . When you go off the pill, you may experience withdrawal bleeding, which is the period-like bleeding you ...
Can you get pregnant on a pill?
Some women get pregnant on the pill, miss a pill and get pregnant, or come off the pill and get pregnant right away. But there are also many women whose bodies need more time. This just means it may take you a while to get pregnant, which is perfectly normal.

Introduction
- Untreated tuberculosis (TB) disease represents a greater hazard to a pregnant woman and her fetus than does its treatment. Treatment of pregnant women should be initiated whenever the probability of TB is moderate to high. Infants born to women with untreated TB may be of lower …
Testing
- The tuberculin skin test is considered both valid and safe to use throughout pregnancy. The TB blood test is safe to use during pregnancy, but has not been evaluated for diagnosing M. tuberculosisinfection in pregnant women. Other tests are needed to show if a person has TB disease.
Contraindications
- The following antituberculosis drugs are contraindicated in pregnant women: 1. Streptomycin 2. Kanamycin 3. Amikacin 4. Capreomycin 5. Fluoroquinolones Women who are being treated for drug-resistant TB should receive counseling concerning the risk to the fetus because of the known and unknown risks of second-line antituberculosis drugs.
Breastfeeding
- Breastfeeding should not be discouraged for women being treated with the first-line antituberculosis drugs because the concentrations of these drugs in breast milk are too small to produce toxicity in the nursing newborn. For the same reason, drugs in breast milk are not an effective treatment for TB disease or LTBI in a nursing infant. Breastfeeding women taking INH …
For More Information
- CDC. Treatment of tuberculosis.MMWR2003; 52 (No. RR–11).
- Errata
- American Thoracic Society/CDC. Targeted tuberculin testing and treatment of latent TB infection.pdf icon. (PDF) MMWR2000: 49(No. RR–6).
- CDC. Guidelines for using the QuantiFERON®-TB Gold test for detecting Mycobacterium tube…
- CDC. Treatment of tuberculosis.MMWR2003; 52 (No. RR–11).
- Errata
- American Thoracic Society/CDC. Targeted tuberculin testing and treatment of latent TB infection.pdf icon. (PDF) MMWR2000: 49(No. RR–6).
- CDC. Guidelines for using the QuantiFERON®-TB Gold test for detecting Mycobacterium tuberculosis infection, United Statespdf icon. (PDF) MMWR2005; 54 (No. RR-15).