The following is the recommended dosage of Xeloda if you’re taking it along with docetaxel
Docetaxel
This medication is used to treat cancer.
Docetaxel
This medication is used to treat cancer.
Full Answer
How many cycles of Xeloda plus Taxotere are needed?
297 women were treated with three cycles of Xeloda plus Taxotere (chemical name: docetaxel), followed by three cycles of Xeloda, Ellence (chemical name: epirubicin), and Cytoxan (chemical name: cyclophosphamide); this was called the Xeloda treatment group
How long has Xeloda been working for You?
I read your message just now and wondering how you are going. i am on Xeloda now for almost a year and was happy that it had been working well for you for Six years. It gave me a bit of hope that it may work for me too.
What is the dosage of Xeloda?
Xeloda is an oblong, peach-colored pill given in either 150 milligram (mg) or 500 mg dosages. It's generally taken twice a day, ideally about 30 minutes after a meal and with plenty of water. 1
Can Xeloda be taken with taxol or Adriamycin?
If you have already been treated with Taxol (paclitaxel) and Adriamycin (doxorubicin) for stage 4 (metastatic) breast cancer and had no response, your healthcare provider may recommend that you take Xeloda by itself.
How long is a course of Xeloda?
Capecitabine is taken as a tablet (orally). You should swallow the tablets whole with water within half an hour of eating a meal. You usually take the capecitabine tablets twice a day (in the morning and evening) for 14 days and then have a 7-day break from taking the tablets. This 21-day period is one treatment cycle.
How many rounds does Xeloda have?
Standard Starting Dose Adjuvant treatment in patients with Dukes C colon cancer is recommended for a total of 6 months [ie, XELODA 1250 mg/m² orally twice daily for 2 weeks followed by a 1-week rest period, given as 3-week cycles for a total of 8 cycles (24 weeks)].
How long can you take Taxotere?
Health care providers administer Taxotere through an IV for one hour ever three weeks, according to the drug's label. Depending on the type of cancer, this can continue for several cycles.
How long does Xeloda work for metastatic breast cancer?
In a phase II trial of 163 paclitaxel-refractory patients with metastatic breast cancer, the overall response rate with Xeloda was 20%, with three complete responses, and the median survival was 12.8 months. A total of 20% of patients experienced a Clinical Benefit Response (a composite assessment of clinical benefit).
What is the success rate of Xeloda?
Xeloda also improved overall survival: 89.2% of the women treated with Xeloda were alive. 83.9% of the women who didn't get chemotherapy were alive.
How long can you be on capecitabine?
Recommended dosing regimens for mono- and combination therapy were 1,250 mg/m2 twice daily for the duration of 14 days, followed by a therapy break of 7 days. The maximum treatment duration per patient was 9 months exclusive of the follow-up period.
How long is TC chemo treatment?
TC refers to a combination of medications given in a special order to treat your cancer. Both drugs given IV once every 3 weeks for a total of 4 cycles. This will total 12 weeks.
Does hair always fall out with Taxotere?
Patients may choose Taxotere because treatment with the drug is once every three weeks — unlike the similar drug Taxol (paclitaxel), which may be given weekly. What many women don't know is that Taxotere has a higher rate of permanent hair loss than similar drugs on the market.
What are the long-term side effects of Taxotere?
But the drug can cause a few long-term side effects. The most common long-term side effects of docetaxel are two types of nerve damage called sensory and motor peripheral neuropathy. Although it is less common, patients have also reported hair loss that lasts for years and appears to be permanent.
How effective is Xeloda for triple-negative breast cancer?
Overall survival was: 85% for people treated with 1 year of Xeloda. 81% for people being monitored.
Can breast cancer spread while on chemo?
While chemotherapy is one of the oldest and most successful ways of treating cancer, it doesn't always work. So, yes, cancer can spread during chemotherapy. Spreading could mean the tumor keeps growing, or that the original tumor shrinks, but cancer metastasizes, forming tumors in other areas of the body.
Who survived triple-negative breast cancer?
Five years after her breast cancer diagnosis, Shalena Prude, now 44, is surviving and thriving. The passage of time has given Shalena a chance to reflect on the complexity of her cancer journey. She remembers there were days when she fought the disease with all her might.
How many cycles of Xeloda did women take?
In the study, 45% of the women completed all eight cycles of Xeloda. About 30% of the women had to take a lower dose of Xeloda because of side effects and 22.5% of the women stopped taking Xeloda because of side effects.
What is Xeloda used for?
Typically, it’s used to treat advanced-stage breast cancer that has stopped responding to certain other chemotherapy medicines. Xeloda is taken orally as a pill.
How do doctors judge the effectiveness of neoadjuvant treatment?
One way doctors judge the effectiveness of neoadjuvant treatment is to look at the tissue removed during surgery to see if any cancer cells are present. If no cancer cells are there, doctors call it a “pathologic complete response.”.
What is the oldest and most prescribed selective estrogen receptor modulator?
Tamoxifen is the oldest and most-prescribed selective estrogen receptor modulator (SERM)....
Does Xeloda help with breast cancer?
A Japanese study has found that women diagnosed with early-stage, HER2-negative breast cancer with residual disease who were treated with Xeloda after surgery had better survival compared to women who didn’t get chemotherapy after surgery.
Does Xeloda improve survival?
Xeloda also improved overall survival: 83.9% of the women who didn’t get chemotherapy were alive. When the researchers grouped the women by age, hormone-receptor-status, cancer grade, or type of neoadjuvant chemotherapy, they found that Xeloda still improved survival.
What is Xeloda used for?
About Xeloda. Xeloda is an antimetabolite chemotherapy . It kills cancer cells by acting as false building blocks in a cancer cell’s genes, causing the cancer cell to die as it gets ready to divide. Xeloda is a pill taken by mouth.
What is the name of the skin reaction that happens when a small amount of chemo medicine leaks out of?
Women in the Xeloda treatment group were much more likely to have hand-foot syndrome, which is also called palmar-plantar erythrodysesthesia. Hand-food syndrome is a skin reaction that happens when a small amount of the chemotherapy medicine leaks out of small blood vessels, usually in the palms of the hands and the soles of the feet. The syndrome can cause numbness, tingling, pain, or a burning/itching sensation.
How many women in the standard treatment group had a recurrence in the same breast?
This difference was statistically significant, which means that it was likely due to the difference in chemotherapy regimens and not just because of chance. 18 women in the standard treatment group had a recurrence in the same breast, compared to 7 women in the Xeloda treatment group.
When was the CBCSG010 study published?
The research was published online on April 10, 2020, by the Journal of Clinical Oncology. Read the abstract of “Adjuvant Capecitabine With Docetaxel and Cyclophosphamide Plus Epirubicin for Triple-Negative Breast Cancer (CBCSG010): An Open-Label, Randomized, Multicenter, Phase III Trial.”. Disease-free survival is how long a person lives without ...
Is Xeloda used for chemotherapy?
Earlier studies have looked at adding Xeloda to standard chemotherapy after surgery for breast cancer overall, but this study looked specifically at adding Xeloda to standard chemotherapy after surgery for triple-negative breast cancer. The study included 585 women who were diagnosed with early-stage triple-negative breast cancer between June 2012 ...
Is Xeloda safe after surgery?
Adding Xeloda (chemical name: capecitabine) to the standard chemotherapy regimen after surgery to remove early-stage triple-negative breast cancer improved disease-free survival without causing any new side effects, according to a Chinese study. The research was published online on April 10, 2020, by the Journal of Clinical Oncology.
Can you take Xeloda after breast cancer surgery?
What this means for you. If you’ve been diagnosed with early-stage triple-negative breast cancer, it’s likely that you will have chemotherapy after surgery to reduce the risk of cancer recurrence. This study suggests that adding Xeloda to the standard chemotherapy regimen after surgery may reduce the risk of recurrence even more.
Uses
Before Taking
- Your healthcare team will evaluate your case to see if Xeloda is a good fit for you. This depends on the type, stage, and size of the cancer. It is also based on where the cancer has spread, previous treatment, and how you responded to that treatment. Before starting Xeloda, you will receive education about the drug and how side effects can be managed. Your healthcare provid…
How It Works
- Xeloda kills cancer cells by imitating part of a cancer cell's genes. This makes the cell die before it can divide, which slows or stops cancer from growing. It is classified as an antimetabolite.
Efficacy
- Efficacy refers to the effectiveness of a medicine. Studies show that Xeloda is an effective medication in the treatment of breast cancer. It helps to decrease the chance of cancer returning and prolongs survival for those with metastatic breast cancer.29 This includes giving it alone, when combined with standard chemotherapy, as a post-surgical treatment, or in combination wi…
Dosage and Schedule
- Xeloda is an oblong, peach-colored pill given in either 150 milligram (mg) or 500 mg dosages. It's generally taken twice a day, ideally about 30 minutes after a meal and with plenty of water.8 The pills should not be crushed, chewed, or dissolved. If you miss a dose, you should wait until your next dose is due and take only that. You should not tak...
Side Effects
- Common side effects of Xeloda include:8 1. Diarrhea 2. Nausea 3. Vomiting 4. Oral mucositis(sores in your mouth, tongue, and throat) 5. Stomach pain 6. Low appetite 7. Dehydration 8. Skin rash or dry, itchy skin 9. Dizziness 10. Fatigue 11. Headache 12. Swelling of the feet, ankles, or hands 13. Neuropathy(tingling of fingers and toes) When taking Xeloda, try t…
Risks
- Taking Xeloda with blood thinners such as Coumadin (warfarin) can cause your blood to thin more. This puts you at risk of bleeding more than usual, even with minor cuts.8 Tell your healthcare provider if you take blood thinners. They may want to prescribe a lower dose of Xeloda or monitor your bloodwork more frequently. To avoid common scrapes and scratches, consider …
Contraindications
- You should not take Xeloda if you have the following:8 1. Severe renal impairment (creatinine clearance below 30 mL/min) 2. Hypersensitivity to Xeloda (capecitabine) or to any of its components or to Carac, Tolak, Efudex, Fluoroplex (5-fluorouracilor 5-FU)
Summary
- Xeloda (capecitabine) is an oral chemotherapy medication that treats metastatic breast cancer. It can be given alone, or in combination with other chemotherapy medications. Typically, it is given when other treatment does not work or stops working. It can also be used for colon and rectal cancers. Xeloda kills cancer cells by imitating part of the cells' genes. This stops or slows the ca…