Treatment FAQ

how long is trental treatment for peyronies

by Una Hamill Published 2 years ago Updated 1 year ago
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Treatments utilized
In general, PTX was prescribed to men at a dose of 400 mg three times daily for an initial period of 4–6 months.

Medication

Depending on the specific device, traction therapy may need to be worn for as little as 30 minutes to as much as three to eight hours a day to achieve benefits. The effectiveness of treatment may also depend on the specific device used. Traction therapy is recommended in the early phase of Peyronie's disease.

Procedures

Pentoxifylline (Pentox) is one of today’s most prescribed treatments for Peyronies disease, it can also be prescribed under the names of Trental, Pentoxil and Flexital. Pentoxifylline is the full name for a prescription drug that is usually given to people with blood flow or circulation problems.

Nutrition

However, there is no clearly established proven efficacy for this medicaiton being a Peyronie’s Disease cure or effective treatment in the peer-reviewed published literature. Pentoxifylline is a medication that has been used for many years for the treatment of intermittent leg cramping (claudication).

How long should I wear traction therapy for Peyronie's disease?

The recommended daily dose is 4 (0.5gram) tablets or 6 capsules, and the number of pills patients are asked to take discourages many from going with this Peyronie’s treatment. This medication was popular in the 1990s but is no longer in use.

What is the best treatment for Peyronies disease?

Is pentoxifylline a Peyronie’s Disease cure?

How many Peyronie’s pills should you take a day?

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How long does the treatment for Peyronie's disease take?

Peyronie disease often happens in a mild form that heals on its own in 6 to 15 months. There is no cure for Peyronie disease. A wide variety of medicines may be tried. Most are taken by mouth, but some are injected into the plaque.

Does pentoxifylline cure Peyronie's?

Pentoxifylline is a nonselective phosphodiesterase inhibitor thought to have anti-inflammatory and antifibrogenic activity. It has been used widely to treat other fibrotic disorders, which led the research team to propose that it might be an effective treatment for Peyronie's disease.

How many injections does it take to cure Peyronie's disease?

Initially, most patients start with a series of six Verapamil injections every two weeks. Your provider will assess your progress to decide if you need further treatment. Xiaflex injections are the only FDA-approved medical therapy for PD. The enzyme in the drug reduces the plaque, improving penile curvature.

How long does it take for Xiaflex to work for Peyronie's disease?

Some men may see improvements after one or two cycles, while men with severe curvatures may benefit more from three or four cycles.

How quickly does pentoxifylline work?

Although you may feel the effects of this medication in 2-4 weeks, you may need to take it for up to 8 weeks before you feel the full effect of pentoxifylline. Pentoxifylline controls the symptoms of circulation problems, but does not cure them. Continue to take pentoxifylline even if you feel well.

How do you break up Peyronie's scar tissue?

Injections that go right into the scar tissue are able to break down the scar and improve the curvature in the penis. Medications can be used in the acute phase, or in men who aren't sure if they want surgery. Medications rarely result in a straight penis.

What is the success rate of Xiaflex?

Studies have shown 34% improvement in penile curvature in men who underwent treatment with Xiaflex injection compared to 18% improvement in men treated with saline injection.

What is the newest treatment for Peyronie's disease?

Xiaflex (collagenase clostridium histolyticum) is an FDA approved prescription medicine that is administered by a trained professional only. Xiaflex is injected directly into the hardened tissue in two courses, and the area is massaged to successfully break down the scar tissue.

What is the most effective treatment for Peyronie's disease?

Surgery has been shown to be the most effective treatment for Peyronie's disease to correct the curvature of the penis. However, it is usually only recommended in severe cases for patients who fail to respond to non-surgical therapy and have curvature for longer than 12 months.

How long is XIAFLEX treatment?

Each treatment cycle is about 6 weeks apart. In between cycles, follow your doctor's instructions on straightening and stretching the penis. Tell your doctor if you have trouble stretching or straightening your penis or if new pain occurs.

Can XIAFLEX be repeated?

Xiaflex® 0.58 mg, 2 injections separated by 1 to 3 days, repeated after 6 weeks for up to 4 treatment cycles. 0.25 mL injections....Condition or diseaseIntervention/treatmentPhasePeyronie's DiseaseDrug: Xiaflex® 0.58 mgPhase 4Dec 6, 2018

How often is XIAFLEX given?

Xiaflex is usually given in a treatment cycle of 1 to 3 injections given 4 weeks apart.

What is the best treatment for Peyronie's disease?

Traction therapy is recommended in the early phase of Peyronie's disease. It's the only treatment shown to improve penile length. Traction therapy may also be used in the chronic phase of the disease, combined with other treatments or after surgery for a better outcome.

How to diagnose Peyronie's disease?

Tests to diagnose Peyronie's disease and understand exactly what's causing your symptoms might include the following: Physical exam. Your doctor will feel (palpate) your penis when it's not erect, to identify the location and amount of scar tissue. He or she might also measure the length of your penis.

How long does a penile pain last?

The acute phase happens early in the disease and may last only two to four weeks but sometimes lasts for up to a year or longer. Chronic phase.

What is the technique of administering verapamil and steroid?

A technique known as iontophoresis uses an electric current to administer a combination of verapamil and a steroid noninvasively through the skin. Available research has shown conflicting results on penile curvature and erectile function.

What is the purpose of ultrasound for peyronies?

Ultrasound tests use sound waves to produce images of soft tissues. These tests can show the presence of scar tissue, blood flow to the penis and any other abnormalities. Care at Mayo Clinic. Our caring team of Mayo Clinic experts can help you with your Peyronie's disease-related health concerns Start Here.

How does Peyronie's disease affect your relationship?

Peyronie's disease can be a source of significant anxiety and create stress between you and your sexual partner. Here are some tips for coping with Peyronie's disease: Explain to your partner what Peyronie's disease is and how it affects your ability to have sex.

How long should I wear traction devices?

Depending on the specific device, traction therapy may need to be worn for as little as 30 minutes to as much as three to eight hours a day to achieve benefits. The effectiveness of treatment may also depend on the specific device used. Traction therapy is recommended in the early phase of Peyronie's disease.

What is the best treatment for peyronies?

Vitamin E (400-1200u) (oral) For decades, Vitamin E has been commonly prescribed Peyronie’s disease treatment because it is inexpensive and can be an effective treatment for scarring (of the skin). In the past, when men wanted to try a pill, Vitamin E was suggested as an option because although we did not necessarily think it would be effective, ...

How to cure Peyronie's disease?

In many cases, the best Peyronie’s disease treatment is surgery. There are primarily two different types of surgery, with Dr. Gelman advising the patient to undergo either a penile plication ...

What is the name of the drug that treats Peyronie's disease?

Xiaflex. There is a fairly new “kid on the block” injection therapy being used to treat Peyronie’s Disease when the disease is stable and there is at least 30 degrees of curvature (not downward). It is called Xiaflex (collagenase clostridium histolyticum). The manufacturer was Auxillium (now owned by Endo Pharmaceuticals).

What is penis curvature?

Penile curvature is generally related to the development of a dense inelastic plaque within the penis. In order for creams, pills or other treatments to be effective, they need to change the affected tissue from a dense scar back to elastic, supple, and healthy tissue.

Is Peyronie's disease non surgical?

While a number of non-surgical treatments are currently available, these treatments are generally not highly effective. Non-surgical Peyronie’s disease treatment is not effective because of the nature ...

What is the best medication for peyronies?

Pentoxifylline For Peyronies Disease. Pentoxifylline (Pentox) is one of today’s most prescribed treatments for Peyronies disease, it can also be prescribed under the names of Trental, Pentoxil and Flexital.

What is the purpose of pentoxifylline?

Pentoxifylline is mainly used to help improve circulation and can improve aching, cramps and tiredness, it helps to reduce the thickness of the blood to allow it to flow easier through the blood vessels .

Does Pentoxifylline help with erections?

By reducing the thickness of the blood, it can help reduce scarring and calcification of the plaques that cause peyronies, it can often have a beneficial effect in improving erections. Pentoxifylline should only be prescribed by a doctor, it can cause some side effects and these to be considered before taking.

Does pentoxifylline work?

Is Pentoxifylline Guaranteed To Work. There are some good reports of Pentoxifylline reducing both scarring and the calcification of plaques, however, as with all drugs and treatments, what works for some will not for others, some find that the side effects cause them to discontinue use, others do not experience any problems.

How long does it take for Peyronie's disease to cure?

In most cases, Peyronie’s disease gets cured on its own with time. However, doctors suggest a waiting period of 1-2 years before they can correct it. Mild cases however, rarely need any treatment.

How to cure Peyronie's disease?

Add a tablespoon of fresh, dried, and crushed leaves of the Gotu Kola herb in hot water. Take the saucepan off the flame after about 7-10 minutes of boiling. Add a teaspoon of honey to the tea and then drink it while it’s hot. Do this twice or thrice a day to cure Peyronie’s Disease traction and plaque.

How to cure bending of penis?

Crush and grind a handful of raw almonds into a fine powder and add 4-5 tablespoons of it to a glass of warm milk. Stir well to prepare a creamy almond milkshake. Drink it twice a day on a daily basis for the cure of bending of the penis during erection .

How to get rid of pain from erection?

Blend half a cup of raw apple cider vinegar with a cup of warm water to prepare a diluted apple cider vinegar solution. Drink the solution twice or thrice a day on a daily basis for the cure of pain during penis erection.

What are some good foods to eat to help with Peyronie's disease?

Almonds are richly packed vitamin E that aids in healthy blood and promote regular flow to the penis. Eating almonds that a steeped with minerals like copper, manganese, and zinc, can cut down on stress and anxiety and there by providing relief from mental issues associated with Peyronie’s Disease.

What is the name of the condition where the penis bends in a curved direction?

Peyronie’s Disease ( 1) is a type of erectile dysfunction which is characterized by the abnormal bending of the penis in a curved direction which makes the position of erection very painful to maintain. The affliction of the disease gets marked by the development of the fibrous scar tissues in the deep penile tissues.

What is the best oil for Peyronie's disease?

Ylang-Ylang. Ylang-ylang essential oil ( 2) is a powerful natural remedy for Peyronie’s Disease . It can also get used for the cure of Peyronie’s Disease cancer.

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Diagnosis

Treatment

Clinical Trials

Coping and Support

Medically reviewed by
Dr. Pawan Katti
Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Initially the condition is monitored and if there is no improvement, then it is treated by medication or surgery based on the severity.
Medication

Hemorrheologic agents: Improve blood flow and reduce the amount of scar tissue.

Pentoxifylline


Enzymes: Used to improve the curvature and problems associated with the condition.

Collagenase clostridium histolyticum


Anti hypertensive drugs: Used to treat high blood pressure.

Verapamil


Proteins: It disrupts the production of scar tissues and breaks it down.

Interferon

Procedures

Plication: Suturing (plicating) the unaffected side results in a straightening of the penis.

Incision and grafting: Cuts are made in scar tissue to stretch out the sheath and allow the penis to straighten.

Iontophoresis: Verapamil and a steroid are administered noninvasively to improve the penile curvature and erectile function.

Penile implant surgery: Used to replace the spongy tissue that fills with blood during an erection.

Nutrition

Foods to eat:

  • NA

Foods to avoid:

  • NA

Specialist to consult

Primary care physician
Specializes in the acute and chronic illnesses and provides preventive care and health.

Preparing For Your Appointment

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