How does Remdesivir injection work to treat COVID-19?
Remdesivir is in a class of medications called antivirals. It works by stopping the virus from spreading in the body.
What are the side effects of Remdesivir?
Remdesivir may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:• nausea• constipation• pain, bleeding, bruising of the skin, soreness, or swelling near the place where the medication was injected
Is Remdesivir approved to treat COVID-19?
Remdesivir is a nucleotide analogue prodrug that is approved to treat COVID-19 in certain patients.Mar 2, 2022
How long does someone typically stay on a ventilator due to COVID-19?
Some people may need to be on a ventilator for a few hours, while others may require one, two, or three weeks. If a person needs to be on a ventilator for a longer period of time, a tracheostomy may be required. During this procedure, a surgeon makes a hole in the front of the neck and inserts a tube into the trachea.Jun 2, 2020
Are long term side effects possible with the COVID-19 vaccine?
Benefits of Vaccination Outweigh the Risks Serious side effects that could cause a long-term health problem are extremely unusual following any vaccination, including COVID-19 vaccination.
Is it possible to have lingering symptoms of COVID-19?
"Some symptoms of COVID-19 linger longer than others," says Dr. Septimus. "In particular, fatigue and loss of taste and smell can persist beyond the period of contagion."While uncomfortable and/or inconvenient, Dr. Septimus adds that these lingering symptoms aren't too worrisome for most people.Jan 5, 2022
Is Remdesivir approved in Europe for treatment of COVID-19?
Since July 2020, remdesivir has been conditionally approved in Europe for the treatment of coronavirus disease (COVID-19) in adults and adolescents aged 12 years and older with pneumonia who require supplemental oxygen but no invasive ventilation.Jul 6, 2021
What is the first drug that was approved by the FDA to treat COVID-19?
Remdesivir is the first drug approved by the FDA for treatment of hospitalized COVID patients over the age of 12.Jan 25, 2022
Which drug is approved by FDA to treat COVID-19?
Veklury (Remdesivir) is an antiviral drug approved for use in adults and pediatric patients [12 years of age and older and weighing at least 40 kilograms (about 88 pounds)] for the treatment of COVID-19 requiring hospitalization.Mar 31, 2022
How does a ventilator help with breathing problems of COVID-19?
When your lungs inhale and exhale air normally, they take in oxygen your cells need to survive and expel carbon dioxide. COVID-19 can inflame your airways and essentially drown your lungs in fluids. A ventilator mechanically helps pump oxygen into your body.Aug 9, 2021
How can ventilators help with the recovery of COVID-19?
When your lungs inhale and exhale air normally, they take in oxygen your cells need to survive and expel carbon dioxide. COVID-19 can inflame your airways and essentially drown your lungs in fluids.A ventilator mechanically helps pump oxygen into your body.Aug 9, 2021
What is the recovery time for COVID-19 patients with Acute Respiratory Distress Syndrome (ARDS)?
Most people who survive ARDS go on to recover their normal or close to normal lung function within six months to a year. Others may not do as well, particularly if their illness was caused by severe lung damage or their treatment entailed long-term use of a ventilator.
Monitoring and Adverse Effects
- Remdesivir can cause gastrointestinal symptoms (e.g., nausea), elevated transaminase levels, an increase in prothrombin time without a change in the international normalized ratio, and hypersensitivity reactions. Liver function tests and prothrombin time tests should be performed …
Drug-Drug Interactions
- Currently, no clinical drug-drug interaction studies of remdesivir have been conducted. In vitro, remdesivir is a minor substrate of cytochrome P450 (CYP) 3A4 and a substrate of the drug transporters organic anion transporting polypeptide (OATP) 1B1 and P-glycoprotein. It is also an inhibitor of CYP3A4, OATP1B1, OATP1B3, and multidrug and toxin extrusion protein 1 (MATE1).…
Considerations in Pregnancy
- Remdesivir should not be withheld from pregnant patients if it is otherwise indicated. Pregnant patients were excluded from the clinical trials that evaluated the safety and efficacy of remdesivir for the treatment of COVID-19, but preliminary reports of remdesivir use in pregnant patients from small studies and case reports are reassuring.13 Among 86 pregnant and postpartum hospitaliz…
Considerations in Children
- Remdesivir is available through an FDA EUA for the treatment of COVID-19 in hospitalized pediatric patients weighing 3.5 kg to <40 kg or aged <12 years and weighing ≥3.5 kg. There are insufficient data on the safety and efficacy of using remdesivir to treat COVID-19 in hospitalized pediatric patients aged <12 years or weighing <40 kg because these populations have not been …
Clinical Trials
- Several clinical trials that are evaluating the use of remdesivir for the treatment of COVID-19 are currently underway or in development. Please see ClinicalTrials.govfor the latest information.