Treatment FAQ

how long is non hodgkin's lymphoma treatment

by Nellie Jaskolski PhD Published 2 years ago Updated 2 years ago
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Treatment is normally given in short daily sessions, Monday to Friday, usually for no more than 3 weeks. You shouldn't have to stay in hospital between appointments.

Medication

A typical treatment regimen involves taking tablets daily for two weeks followed by two weeks’ break, and repeating this pattern for about six months. Some people we spoke to were treated with a combination of tablet and intravenous chemotherapy. How long does it take for lymphoma to cure? Treatment usually lasts about six months.

Procedures

It's part of the national guidelines for treating some types of NHL. How Long You Can Expect to Watch and Wait "About half of all patients can put off treatment for at least 3 years," Abetti says....

Therapy

Chemo is the main treatment for most people with non-Hodgkin lymphoma (NHL). ... These depend on the type and dose of drugs given and how long treatment lasts. Common side effects can include: Hair loss; Mouth sores; ... Freedman AS, Jacobson CA, Mauch P, Aster JC. Chapter 103: Non-Hodgkin’s lymphoma. In: DeVita VT, Lawrence TS, ...

Self-care

Most often, the treatment is chemotherapy (chemo), usually with a regimen of 4 drugs known as CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone), plus the monoclonal antibody rituximab (Rituxan). This regimen, known as …

Nutrition

May 04, 2021 · Your doctor will likely ask you about your personal and family medical history. He or she may then have you undergo tests and procedures used to diagnose non-Hodgkin's lymphoma, including: Physical exam. Your doctor checks for swollen lymph nodes, including in your neck, underarm and groin, as well as for a swollen spleen or liver.

What is the best treatment for non Hodgkin lymphoma?

Aug 01, 2018 · Living as a Non-Hodgkin Lymphoma Survivor. For many people with non-Hodgkin lymphoma, treatment can destroy the lymphoma. Completing treatment can be both stressful and exciting. You may be relieved to finish treatment, but find it hard not to worry about the lymphoma coming back. (When cancer comes back after treatment, it is called recurrence .)

Can non-Hodgkin lymphoma come back?

The ABVD regimen (for at least 6 cycles) is often used, but some doctors favor more intense treatment with the Stanford V regimen for 3 cycles, or up to 8 cycles of the BEACOPP regimen if there are several unfavorable prognostic factors. Another option for some people might be chemo plus the drug brentuximab vedotin (Adcetris).

How long can you have monoclonal antibody treatment for non-Hodgkin lymphoma?

SOURCES: American Society of Clinical Oncology: “Lymphoma - Non-Hodgkin: Stages.” Leukemia and Lymphoma Society: “NHL Staging,” “Facts and Statistics,” “Treatment for Aggressive NHL ...

What are the stages of non-Hodgkin's lymphoma?

Radiotherapy is most often used to treat early-stage non-Hodgkin lymphoma, where the cancer is only in 1 part of the body. Treatment is normally given in short daily sessions, Monday to Friday, usually for no more than 3 weeks. You shouldn't have to stay in hospital between appointments.

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How many rounds of chemo is normal for non Hodgkin's lymphoma?

If the lymphoma shrinks, a total of 6 cycles of chemo plus rituximab is usually given. Other options for initial treatment include rituximab alone or chemo alone (either one or several drugs).

How long is chemo for non Hodgkin's lymphoma?

So, you will be coming in for approximately five months for your chemotherapy. Depending on where your cancer is and what type of cancer you have will be dependent on how often you come in for treatment.

Can non Hodgkin's lymphoma be completely cured?

Yes, NHL is a very treatable disease and curable in many cases, particularly with aggressive NHL. Before treatment begins, it is necessary to know how far the cancer has advanced. This is called the stage of the disease.Sep 15, 2019

How long does non Hodgkin's lymphoma last?

Most people with indolent non-Hodgkin lymphoma will live 20 years after diagnosis. Faster-growing cancers (aggressive lymphomas) have a worse prognosis.

How serious is non Hodgkin's lymphoma?

NHL is a serious condition but commonly has a relatively promising outlook. Most people with NHL survive at least 5 years after a diagnosis. However, older people are more likely to die from the condition. Other factors that affect the outlook include the stage and spread of the cancer.Sep 29, 2021

What type of lymphoma is not curable?

Lymphoplasmacytic lymphoma or Waldenstrom macroglobulinemia. This is a rare, slow-growing type of lymphoma. It's found mainly in the bone marrow, lymph nodes, and spleen. People with this type usually live many years with the disease, but it's usually not curable.

Is Non Hodgkins or Hodgkins worse?

Is Hodgkin's worse than non-Hodgkin's lymphoma? The progression of Hodgkin's lymphoma is typically more predictable than that of non-Hodgkin's lymphoma. The prognosis of Hodgkin's lymphoma is also better than that of non-Hodgkin's lymphoma since non-Hodgkin's lymphoma is often diagnosed at a more advanced stage.Aug 24, 2021

Can you go into remission with non-Hodgkin's lymphoma?

Patients who go into remission are sometimes cured of their disease. Treatment can also keep non-Hodgkin lymphoma (NHL) in check for many years, even though imaging or other studies show remaining sites of disease. This situation may be referred to as a “partial remission.”

Can you live a long life after lymphoma?

There are very few cancers for which doctors will use the word 'cure' right off the bat, but Hodgkin lymphoma (HL), the most common cancer diagnosis among children and young adults, comes pretty darn close: Ninety percent of patients with stages 1 and 2 go on to survive 5 years or more; even patients with stage 4 have ...Apr 26, 2018

What are the final stages of non-Hodgkin's lymphoma?

Symptoms of stage 4 lymphomafatigue.night sweats.recurrent fevers.weight loss.itching.bone pain, if your bone marrow is affected.loss of appetite.abdominal pain.More items...

How often does non-Hodgkin's lymphoma relapse?

Complete remission can be achieved in 60-80% of adults with diffuse aggressive non-Hodgkin's lymphoma. However, 20-40% of them will subsequently relapse.

Can you survive stage 4 non-Hodgkin's lymphoma?

The survival rate of stage 4 lymphoma is lower than that of the other stages, but doctors can cure the condition in some cases. People with a diagnosis of stage 4 lymphoma should discuss their treatment options and outlook with their doctor.

Diffuse Large B-Cell Lymphoma

Diffuse large B-cell lymphoma (DLBCL) tends to grow quickly. Most often, the treatment is chemotherapy (chemo), usually with a regimen of 4 drugs k...

Small Lymphocytic Lymphoma (and Chronic Lymphocytic Leukemia)

Small lymphocytic lymphoma (SLL) and chronic lymphocytic leukemia (CLL) are considered different versions of the same disease. The main difference...

Extranodal Marginal Zone B-Cell Lymphoma – Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma

Gastric (stomach) MALT lymphoma, the most common type, often occurs as a result of a chronic infection with the bacterium H. pylori, and it often r...

Nodal Marginal Zone B-Cell Lymphoma

This rare type of lymphoma is generally slow growing (indolent), and it often doesn’t need to be treated right away. If it does need treatment, it...

Splenic Marginal Zone B-Cell Lymphoma

This is typically a slow-growing lymphoma. If it is not causing symptoms, it is often watched closely without treating it right away.About 1 in 3 p...

Lymphoplasmacytic Lymphoma (Waldenstrom Macroglobulinemia)

The main treatment for this lymphoma is usually chemo or rituximab. For more detailed information see Treating Waldenstrom Macroglobulinemia.

Primary Central Nervous System (CNS) Lymphoma

This lymphoma begins in the brain or spinal cord. It often develops in older people or those with immune system problems caused by AIDS or drugs gi...

How long is chemo treatment for lymphoma?

A typical treatment regimen involves taking tablets daily for two weeks followed by two weeks’ break, and repeating this pattern for about six months. Some people we spoke to were treated with a combination of tablet and intravenous chemotherapy.

How long does it take for lymphoma to cure?

Treatment usually lasts about six months. To treat slow-growing follicular lymphoma, your doctor may start by prescribing rituximab and chemotherapy drugs.

What is the survival rate for Stage 1 lymphoma?

For stage I NHL, the 5-year survival rate is more than 83%. For stage II the 5-year survival rate is close to 76% and for stage III it is more than 70%. For stage IV NHL, the 5-year survival rate is around 63%. These survival rates vary depending on the cancer’s stage and subtype.

What was your first lymphoma symptom?

The best way to find HL early is to be on the lookout for possible symptoms. The most common symptom is enlargement or swelling of one or more lymph nodes, causing a lump or bump under the skin which usually doesn’t hurt. It’s most often on the side of the neck, in the armpit, or in the groin.

Can you live 20 years with lymphoma?

Most people with indolent non-Hodgkin lymphoma will live 20 years after diagnosis. Faster-growing cancers (aggressive lymphomas) have a worse prognosis. They fall into the overall five-year survival rate of 60%.

How many chemo sessions are needed for lymphoma?

Treatment for many patients is chemotherapy (usually 2 to 4 cycles of the ABVD regimen ), followed by radiation to the initial site of the disease (involved site radiation therapy, or ISRT). Another option is chemotherapy alone (usually for 3 to 6 cycles) in selected patients.

How successful is chemotherapy for lymphoma?

Usually chemotherapy works very well for most people with Hodgkin lymphoma. But sometimes the lymphoma may not completely respond to the treatment. If this happens it can still be treated successfully. Your doctor may talk to you about having more intensive chemotherapy with a stem cell transplant.

What are the pros and cons of watching and waiting?

Pros. The major benefit of watch and wait is that you don't have to deal with treatment side effects, Tsai says . When you skip chemotherapy, you won't get symptoms like sickness, infection, and hair loss. Another benefit is your lymphoma cells won't get resistant to medicine, which is a problem for some people.

How often should I have a checkup?

If you choose to delay treatment, your doctor will keep a close eye on you and look for changes. You'll have checkups every 3-6 months, or even more often . The major benefit of watch and wait is that you don't have to deal with treatment side effects, Tsai says.

How long can you wait to get treatment for NHL?

"About half of all patients can put off treatment for at least 3 years," Abetti says. "Some patients can be in watch-and-wait mode for 10 years or more .". It's possible you'll never need treatment.

Can you wait to see your doctor if you have a slow growing NHL?

Also, if you aren't very good about visiting your doctor, watch and wait may not be a good choice.

Can you wait to see a doctor for lymphoma?

Also, if you aren't very good about visiting your doctor, watch and wait may not be a good choice. If you wait too long to set up an appointment, your lymphoma may get worse. Pagination. 1.

Does NHL affect kidneys?

Your NHL doesn't affect your heart, lungs, kidneys, or other key organs. "Watch and wait can also be the best approach for some patients diagnosed with widespread NHL that treatment won't likely cure," Abetti says. Even if it's widespread, it may remain stable for years.

Is it hard to accept that you're not actively treating your cancer?

There's a risk that your cancer may change to a fast-growing type. It may also be hard to accept that you're not actively treating your cancer. Tsai says many of his patients struggle with this, but they feel better when they learn that watch and wait is an accepted strategy.

What is the treatment for lymphoma?

Chemotherapy (chemo) is the use of anti-cancer drugs that are usually injected into a vein (IV) or taken by mouth. These drugs enter the bloodstream and reach almost all areas of the body, making this treatment very useful for lymphoma.

What is the name of the drug that is given to lymphoma patients?

To treat lymphoma that might have reached these areas, chemo may also be given into the CSF. This is called intrathecal chemo. The chemo drugs most often used for intrathecal chemo are methotrexate and cytarabine.

How long does chemo last?

Each chemo cycle generally lasts for several weeks.

What happens when you kill lymphoma cells?

Killing the lymphoma cells releases their contents into the bloodstream. This can overwhelm the kidneys, which can’t get rid of all of these substances at once. This can lead to the build-up of certain minerals in the blood and even kidney failure. The excess minerals can lead to heart and nervous system problems.

Can chemo be used for lymphoma?

Many chemo drugs are useful in treating lymphoma. Often, several drugs are combined. The number of drugs, their doses, and the length of treatment depend on the type and stage of the lymphoma. Here are some of the drugs more commonly used to treat lymphoma (divided into groups based on how they work):

Can chemo be delayed?

If serious side effects occur, the dose of chemo may be reduced or treatment may be delayed. There are often ways to lessen these side effects. For example, drugs can be given to prevent or reduce nausea and vomiting. Certain chemo drugs can have other possible side effects. For example:

Does lymphoma go away?

Treatment of this infection can often make the lymphoma go away. This is most often done with a combination of antibiotics along with drugs called proton pump inhibitors, which lower stomach acid levels. In a similar way, splenic marginal zone B-cell lymphoma is sometimes linked to infection with the hepatitis C virus.

How many chemo drugs are needed for lymphoma?

It is usually treated in the hospital with intensive chemo, which usually includes at least 5 chemo drugs. Rituximab may also be added. Some examples of chemo regimens used for this lymphoma include:

What is the treatment for follicular lymphoma?

If treatment is needed for follicular lymphoma that is only in 1 lymph node group or in 2 nearby groups that are both above or below the diaphrag m (the thin muscle separating the chest from the abdomen), the preferred treatment is radiation therapy to the lymph node areas affected by lymphoma (called involved site radiation ). Other choices include treatment with chemo plus a monoclonal antibody (rituximab [Rituxan] or obinutuzumab [Gazyva]), or rituximab alone, which might be followed by radiation therapy.

How to treat malt lymphoma?

Early-stage gastric MALT lymphomas are treated with antibiotics combined with drugs that block acid secretion by the stomach (called proton pump inhibitors ). Usually the drugs are given for 10 to 14 days. This may be repeated after a couple of weeks. Examination of the stomach lining using upper endoscopy (where a flexible tube with a viewing lens is passed down the throat and into the stomach) is then repeated at certain intervals to see if the H. pylori is gone and if the lymphoma has shrunk. About 2 out of 3 of these lymphomas go away completely with antibiotic treatment, but it can sometimes take several months to be effective. In cases where symptoms need to be relieved before the antibiotics take effect or where antibiotics don’t shrink the lymphoma, radiation therapy to the area is often the preferred treatment. The monoclonal antibody rituximab may be another option.

What is a chemo drug?

The chemo can be a single drug (such as bendamustine) or a combination of drugs, such as the CHOP ( cyclophosphamide, doxorubicin, vin cristine, prednisone) or CVP ( cyclophosphamide, vincristine, prednisone) regimens. If some lymph nodes are very large from the lymphoma, radiation may be used to reduce symptoms.

What happens if you have a positive PET scan after chemo?

If the PET/CT scan is positive (shows possible active lymphoma), radiation may be needed.

What is the best treatment for mantle cell lymphoma?

For mantle cell lymphomas that don’t respond or that come back after initial treatment, chemo with drugs such as bendamustine, bortezomib (Velcade), cladribine, fludarabine, or lenalidomide (Revlimid) may be used, sometimes along with other chemo drugs or with rituximab.

What is the treatment for diffuse large B-cell lymphoma?

Diffuse large B-cell lymphoma (DLBCL) tends to grow quickly. Most often, the treatment is chemotherapy (chemo), usually with a regimen of 4 drugs known as CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone), plus the monoclonal antibody rituximab (Rituxan). This regimen, known as R-CHOP, is most often given in cycles 3 weeks apart.

What is bone marrow transplant?

Bone marrow transplant, also known as a stem cell transplant, involves using high doses of chemotherapy and radiation to suppress your bone marrow and immune system. Then healthy bone marrow stem cells from your body or from a donor are infused into your blood where they travel to your bones and rebuild your bone marrow.

What tests can be done to detect lymphoma?

Imaging tests. Your doctor may recommend imaging tests to look for signs of lymphoma cells elsewhere in your body. Tests may include CT, MRI and positron emission tomography (PET). Lymph node test. Your doctor may recommend a lymph node biopsy procedure to remove all or part of a lymph node for laboratory testing.

What tests can be done to check for swollen lymph nodes?

Physical exam. Your doctor checks for swollen lymph nodes, including in your neck, underarm and groin, as well as for a swollen spleen or liver. Blood and urine tests. Blood and urine tests may help rule out an infection or other disease. Imaging tests.

What is car T cell therapy?

A specialized treatment called chimeric antigen receptor (CAR)- T cell therapy takes your body's germ-fighting T cells, engineers them to fight cancer and infuses them back into your body. CAR -T cell therapy might be an option for certain types of B-cell non-Hodgkin's lymphoma that haven't responded to other treatments.

What is a spinal tap?

Lumbar puncture (spinal tap). If there's a concern that the lymphoma may affect the fluid around your spinal cord, your doctor might recommend a procedure to remove some of the fluid for testing. During a spinal tap, the doctor inserts a small needle into the spinal canal in your lower back.

Where is bone marrow removed?

In a bone marrow aspiration, a doctor or nurse uses a thin needle to remove a small amount of liquid bone marrow, usually from a spot in the back of your hipbone (pelvis). A bone marrow biopsy is often done at the same time. This second procedure removes a small piece of bone tissue and the enclosed marrow.

What is the best way to kill cancer cells?

Radiation therapy. Radiation therapy uses high-powered energy beams, such as X-rays and protons, to kill cancer cells. During radiation therapy, you lie on a table and a large machine moves around you, directing the energy beams to specific points on your body.

Why do you need a CT scan for lymphoma?

You may need frequent blood tests to check that you have recovered from treatment and to look for possible signs of problems such as lymphoma recurrence. Blood counts can also sometimes become abnormal because ...

Why is my blood count abnormal?

Blood counts can also sometimes become abnormal because of a disease of the bone marrow called myelodysplasia, which can sometimes lead to leukemia. Some chemotherapy drugs can cause this disease. For more on this, see Myelodysplastic Syndromes.

What is a survivorship plan?

This plan might include: A schedule for other tests you might need in the future, such as early detection (screening) tests for other types of cancer, or tests to look for long-term health effects from your cancer or its treatment.

How to plan for cancer survivorship?

Talk with your doctor about developing a survivorship care plan for you. This plan might include: 1 A suggested schedule for follow-up exams and tests 2 A schedule for other tests you might need in the future, such as early detection (screening) tests for other types of cancer, or tests to look for long-term health effects from your cancer or its treatment 3 A list of possible late- or long-term side effects from your treatment, including what to watch for and when you should contact your doctor 4 Diet and physical activity suggestions

Does lymphoma go away after treatment?

You may be relieved to finish treatment, but find it hard not to worry about the lymphoma coming back. (When cancer comes back after treatment, it is called recurrence .) This is a very common worry if you’ve had cancer. For some people, the lymphoma may never go away completely. These people may get regular treatments with chemo, radiation, ...

Can non-Hodgkin lymphoma patients get other cancers?

People who’ve had non-Hodgkin lymphoma can still get other cancers. In fact, lymphoma survivors are at higher risk for getting some other types of cancer. Learn more in Second Cancers After Non-Hodgkin Lymphoma.

Does lymphoma go away?

For some people, the lymphoma may never go away completely. These people may get regular treatments with chemo, radiation, or other therapies to help keep the lymphoma in check for as long as possible and to help relieve symptoms. Learning to live with lymphoma that doesn’t go away can be difficult and very stressful.

What is the best treatment for stem cell transplant?

For those who don’t respond to treatment, chemo using different drugs or high-dose chemo (and possibly radiation) followed by a stem cell transplant may be recommended. Treatment with an immunotherapy drug such as brentuximab vedotin (Adcetris), nivolumab (Opdivo), or pembrolizumab (Keytruda) might be another option.

How many cycles of chemo for ABVD?

Treatment is generally more intense than that for favorable disease. It typically starts with chemotherapy (usually with the ABVD regimen for 4 to 6 cycles or other regimens such as 3 cycles of Stanford V). PET/CT scans are often done after several cycles of chemo to see if (and how much) more treatment is needed.

What to do if you have HL?

If HL is still there after these treatments, most doctors would recommend high-dose chemo (and possibly radiation) followed by an autologous stem cell transplant, if it can be done. If cancer still remains after this, an allogeneic stem cell transplant may be an option.

Why do you need a PET scan after chemo?

If a person can’t have chemotherapy because of other health issues , radiation therapy alone may be an option.

What is stage 1 and stage 2?

Stages I and II, unfavorable. This group includes HL that is only on one side of the diaphragm (above or below), but has 1 or more of these risk factors: It's bulky (the tumor is large) HL is in 3 or more different areas of lymph nodes. There's cancer outside the lymph nodes (called extranodal involvement)

How to treat lymphoma after treatment?

Treatment for HL should remove all traces of the lymphoma. After treatment, the doctor will do tests such as PET/CT scans to look for any signs of HL. If HL is still there, most experts think that more of the same treatment is unlikely to cure it.

Is Hodgkin Lymphoma treated in children?

Treatment of the disease in children is slightly different from the treatment for adults. Some of these differences are discussed in Treating Hodgkin Lymphoma in Children. For teens with HL who are fully grown, the treatment is usually the same as that for an adult. Treatment options depend on many factors, including:

What does stage 1 mean?

It means the lymphoma is in one area outside your lymph system. Stage I means the lymphoma is in one lymph node, in a group of nodes that are close to each other, or in an organ that has lymphoid tissue, such as the tonsils. In stage IE, the cancer is in one area outside your lymph system.

What does the E mean in NHL?

Stage I means the least amount of cancer. Stage IV is the most advanced. You may see an “E” after stages I, II, or III -- that stands for extranodal. It means the lymphoma is in one area outside your lymph system.

How do you get rid of lymphoma cells?

You can use your own stem cells or get them from a donor. Then, you get high doses of chemotherapy and radiation to kill all the lymphoma cells in your body. After that, the stem cells go into your body, where they grow and rebuild healthy blood cells over time.

What does it mean when you have a tumor in your chest?

You may also hear the term “bulky disease” if you have a large tumor in your chest. It might mean you need more intense treatment. Talk with your doctor about what your cancer stage means and how it impacts your treatment. Your prognosis is a best guess at your chances of recovering from lymphoma after treatment.

Where does lymphoma spread?

Stage IV lymphoma has spread outside your lymph nodes to many places in your body. NHL tends to spread to the bone marrow, liver, lungs, and the fluid around the brain. Continued. Sometimes doctors just call NHL limited or advanced. Stage I and some stage II lymphomas fall into the limited group.

Where is stage III NHL?

Stage III NHL is in lymph nodes on both sides of your diaphragm. If the cancer is also outside lymph system, it’s called stage IIIE. Stage III lymphoma that’s also in your spleen is stage IIIS. If it’s stage IIIS and has spread outside your lymph system, it’s stage IIIE+S. Stage IV lymphoma has spread outside your lymph nodes to many places in your ...

What is the next step for a non-Hodgkin's lymphoma patient?

When you’re diagnosed with non-Hodgkin’s lymphoma (NHL), the next step is to find out the stage of your cancer. That tells you how much lymphoma is in your body, where it is, and if it has spread outside your lymph system, the network that carries immune cells throughout your body. Your doctor uses that information to decide ...

How long does monoclonal antibody therapy last?

For some types of non-Hodgkin lymphoma, you may continue having monoclonal antibody treatment regularly for up to 2 years after initial treatment, in combination with chemotherapy.

What is the treatment for non-Hodgkin lymphoma?

Chemotherapy . Chemotherapy is a widely used treatment for non-Hodgkin lymphoma that involves using medicine to kill cancer cells. It may be used on its own, combined with biological therapy, or combined with radiotherapy. The medication can be given in a number of different ways, depending on the stage of your cancer.

What are the side effects of chemotherapy?

Other possible side effects of chemotherapy include: nausea and vomiting. diarrhoea. loss of appetite. mouth ulcers. tiredness. skin rashes. hair loss. infertility, which may be temporary or permanent (see complications of non-Hodgkin lymphoma for more information)

How long does it take to get rid of lymphoma?

Treatment is normally given in short daily sessions, Monday to Friday, usually for no more than 3 weeks. You shouldn't have to stay in hospital between appointments.

How to treat low grade syphilis?

Wait-and-see approach. If the disease is low grade (slow developing) and you're well, a period of "watch and wait" is often recommended. This is because some people take many years to develop troublesome symptoms and starting treatment immediately is often felt to be unnecessary.

What are the side effects of a syringe?

These can vary, depending on which part of your body is being treated. For example, treatment to your throat can lead to a sore throat , while treatment to the head can lead to hair loss. Other common side effects include: sore and red skin in the treatment area. tiredness.

Can steroids cause weight gain?

feeling agitated. On rare occasions, you may have to take steroids on a long-term basis. Side effects of long-term steroid use include high blood pressure, weight gain, and swelling in your hands, feet and eyelids. The side effects of steroid medication usually start to improve once treatment finishes.

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