how long is chemo treatment for aredia

Precautions

 · How long will a person need chemotherapy, and why? Chemotherapy treatment typically lasts between 3–6 months . However, some people will receive chemotherapy for shorter or longer periods of time.

How long does it take for Aredia to work?

It may be given once every 3 to 4 weeks, once a day for 3 days in a row, or as a single dose that may be repeated after 1 week or longer. The treatment schedule depends on your condition. Your doctor may recommend a calcium supplement and a multivitamin containing vitamin D to take during your treatment.

What is the recommended dose of Aredia?

 · One course of chemo treatment may last between 3 to 6 months. Typically, one course consists of several on-and-off cycles. One cycle usually lasts 2 to 6 weeks.

How long do chemotherapy treatments last?

Pamidronate is given by a drip (infusion) into a vein. It can usually be given in the outpatient department at the hospital. The infusion may be given over 2 to 4 hours. Your doctor or nurse will tell you how long your treatment will take. It is usually given every 3 to 4 weeks. How long pamidronate is given for

How often do you give Aredia for multiple myeloma?

Pamidronate. Chemocare.com uses generic names in all descriptions of drugs. Aredia is the trade name for pamidronate. In some cases, health care professionals may use the trade name aredia when referring to the generic drug name pamidronate. Drug type: Pamidronate is a supportive care drug in the category of bisphosphonates.

How often is Aredia given?

The recommended dose of Aredia in patients with osteolytic bone metastases is 90 mg administered over a 2-hour infusion given every 3-4 weeks.

Is Aredia a chemo drug?

Aredia is a bisphosphonate. Bisphosphonate medications are used to slow down the osteoclast's effects on the bone. In doing this it can be useful in slowing down or preventing the complications (bone pain, fractures, or high calcium levels) of the bone breakdown.

Is pamidronate a chemo?

Pamidronate is a type of drug called a bisphosphonate, which is used to slow the destruction of bone caused by cancer cells. It can also be used in the treatment of increased calcium levels that may occur as a result of a cancer diagnosis. Pamidronate is not a cancer treatment, but a supportive care medicine.

How long after first Zometa do you get flu like symptoms?

Body aches, fever and other flu-like symptoms lasting one to three days are common with the first infusion of a bone agent like zoledronic acid (marketed as Zometa or Reclast).

How long is Pamidronate infusion?

Pamidronate is given by a drip (infusion) into a vein. It can usually be given in the outpatient department at the hospital. The infusion may be given over 2 to 4 hours. Your doctor or nurse will tell you how long your treatment will take.

What is a bone infusion for osteogenesis imperfecta?

Pamidronate strengthens the bone by increasing bone density and corrects the imbalance between bone reabsorption and bone formation which occurs in osteogenesis imperfecta (OI). Pamidronate infusions are most effective when they are given every six weeks in small children and three-monthly in older children.

Does pamidronate affect teeth?

In the present study, pamidronate administration not only inhibited tooth eruption but also negatively affected mandibular growth pattern. Mandibular height and length of the study groups were statistically shorter than the control groups.

What's the side effects of pamidronate?

AdvertisementAbdominal or stomach cramps.black, tarry stools.bloody in the urine or stools.convulsions (seizures)decrease in the amount of urine.drowsiness.fast or irregular heartbeat.headache.More items...•

What are the benefits of pamidronate?

Pamidronate belongs to a class of drugs known as bisphosphonates. It works by slowing the release of calcium from bones to lower blood calcium levels, reducing the risk of broken bones (fractures) and reducing bone pain.

How long does Zometa infusion take?

Zometa infusions are given by a healthcare provider over a period of at least 15 minutes. It's typically done at a healthcare facility, but in some cases, a healthcare provider may give you the drug in your home. For hypercalcemia caused by cancer, Zometa is given as a single dose.

How do I prepare for Zometa infusion?

Immediately prior to having your Zometa injection, you should drink two full glasses of water. You may need to take supplementary calcium or vitamin D if your dietary intake is inadequate. Your doctor will advise you about this. Tell your doctor if you have ever had kidney problems in the past before taking Zometa.

Is Zometa worth taking?

Zometa Can Help Reduce Recurrence Risk of Hormone-Receptor-Positive Disease. Results from three studies all suggest that Zometa can help reduce the risk of cancer recurrence when it's started right after surgery to treat hormone-receptor-positive early-stage breast cancer in postmenopausal and older premenopausal women ...

How long does it take for Aredia to be excreted?

After administration of 30, 60, and 90 mg of Aredia over 4 hours, and 90 mg of Aredia over 24 hours, an overall mean ± SD of 46 ± 16% of the drug was excreted unchanged in the urine within 120 hours. Cumulative urinary excretion was linearly related to dose. The mean ± SD elimination half-life is 28 ± 7 hours. Mean ± SD total and renal clearances of pamidronate were 107 ± 50 mL/min and 49 ± 28 mL/min, respectively. The rate of elimination from bone has not been determined.

How long does Aredia last in dogs?

Two 7-day intravenous infusion studies were conducted in the dog wherein Aredia was given for 1, 4, or 24 hours at doses of 1-20 mg/kg for up to 7 days.

What is Aredia used for?

Aredia, in conjunction with adequate hydration, is indicated for the treatment of moderate or severe hypercalcemia associated with malignancy, with or without bone metastases. Patients who have either epidermoid or non-epidermoid tumors respond to treatment with Aredia. Vigorous saline hydration, an integral part of hypercalcemia therapy, should be initiated promptly and an attempt should be made to restore the urine output to about 2 L/day throughout treatment. Mild or asymptomatic hypercalcemia may be treated with conservative measures (i.e., saline hydration, with or without loop diuretics). Patients should be hydrated adequately throughout the treatment, but overhydration, especially in those patients who have cardiac failure, must be avoided. Diuretic therapy should not be employed prior to correction of hypovolemia. The safety and efficacy of Aredia in the treatment of hypercalcemia associated with hyperparathyroidism or with other non-tumor-related conditions has not been established.

What is pamidronate disodium?

Aredia, pamidronate disodium (APD), is a bone-resorption inhibitor available in 30-mg or 90-mg vials for intravenous administration. Each 30-mg and 90-mg vial contains, respectively, 30 mg and 90 mg of sterile, lyophilized pamidronate disodium and 470 mg and 375 mg of mannitol, USP. The pH of a 1% solution of pamidronate disodium in distilled water is approximately 8.3. Aredia, a member of the group of chemical compounds known as bisphosphonates, is an analog of pyrophosphate. Pamidronate disodium is designated chemically as phosphonic acid (3-amino-1-hydroxypropylidene) bis-, disodium salt, pentahydrate, (APD), and its structural formula is

How long does pamidronate stay in your system?

The mean ± SD body retention of pamidronate was calculated to be 54 ± 16% of the dose over 120 hours.

How many people are over 65 in Aredia?

Of the total number of subjects in clinical studies of Aredia, approximately 20% were 65 and over, while approximately 15% were 75 and over. No overall differences in safety or effectiveness were observed between these subjects and younger subjects, and other reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.

Does Aredia lower phosphate levels?

Serum phosphate levels have been noted to decrease after administration of Aredia, presumably because of decreased release of phosphate from bone and increased renal excretion as parathyroid hormone levels, which are usually suppressed in hypercalcemia associated with malignancy, return toward normal. Phosphate therapy was administered in 30% of the patients in response to a decrease in serum phosphate levels. Phosphate levels usually returned toward normal within 7-10 days.

How often do you take chemo?

Medical professionals typically administer chemotherapy medications in cycles. The duration of each cycle depends on several factors, such as the types of chemotherapy drugs used, the type of cancer a person has, and its response to the medication.

What is a cycle of chemotherapy?

A cycle of chemotherapy is the amount of time that elapses between the start of one round of chemotherapy to the start of the next.

How does a chemo catheter work?

A medical professional must first place a soft plastic tube or “catheter” into a person’s vein when administering IV chemotherapy. The catheter connects to a syringe or plastic bag that contains the chemotherapy medications. These medications then pass through the syringe or IV line , through the catheter, and into the person’s bloodstream.

Why is it important to get chemo in cycles?

Receiving chemotherapy in cycles helps to effectively kill off the cancerous cells, while allowing the person’s body time to replenish its healthy cells.

What is the treatment for cancer?

Chemotherapy is a cancer treatment that involves administering medications to kill cancer cells or stop them from growing.

Can you take chemotherapy alone?

A person may receive a chemotherapy drug on its own or in combination with other chemotherapy drugs. Medical professionals can administer chemotherapy medications in the following ways:

Can you take chemo at home?

People receiving this form of chemotherapy may take these medications at home, although they must do so according to a pre-arranged schedule.

What is a pamidronate injection?

Pamidronate is also used to treat Paget's disease (a condition in which the bones are soft and weak and may be deformed, painful, or easily broken). Pamidronate injection is in a class of medications called bisphosphonates. It works by slowing bone breakdown, increasing bone density (thickness) and decreasing the amount of calcium released from the bones into the blood.

What to tell your doctor about radiation?

tell your doctor if you are being treated with radiation therapy and if you have or have ever had thyroid surgery, seizures, or liver or kidney disease.

What is the treatment for aredia?

Aredia is only part of a complete program of treatment that may also include diet changes and taking calcium and vitamin supplements. Follow your doctor's instructions very closely.

What is Aredia medicine?

Aredia is a bisphosphonate (bis FOS fo nayt) medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures.

How is Aredia injected?

Aredia is injected into a vein through an IV. You may be shown how to use an IV at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of needles, IV tubing, and other items used.

How old do you have to be to take Aredia?

Aredia is not approved for use by anyone younger than 18 years old.

What are the side effects of Aredia?

Aredia side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath;

How long after pamidronate can you use birth control?

Tell your doctor if you become pregnant. You may also need to use birth control for several weeks after your last dose of pamidronate. This medicine can have long-lasting effects on your body.

What to do if you miss Aredia?

Call your doctor for instructions if you miss a dose of Aredia.

What is a pamidronate used for?

Pamidronate is used to treat and prevent problems caused by the effect of cancer on the bones.

How does pamidronate work?

How pamidronate works. Pamidronate reduces the activity of osteoclasts. This can help to reduce pain and strengthen the bone. Pamidronate also reduces the amount of calcium lost from the bones. This helps calcium levels in the blood return to normal.

Can you take pamidronate for pain?

If you are having pamidronate to reduce pain or strengthen your bones, you may continue it for as long as it helps manage the symptoms.

Can pamidronate be given with other cancer?

It can be used to treat: high levels of calcium in the blood caused by cancer that has spread to the bones ( secondary bone cancer) bone weakness or pain caused by myeloma or by breast cancer that has spread to the bones. Pamidronate can be given with other cancer treatments.

What is chemocare.com?

Chemocare.com is designed to provide the latest information about chemotherapy to patients and their families, caregivers and friends. For information about the 4th Angel Mentoring Program visit www.4thangel.org

Is side effect predictable?

Side effects are often predictable in terms of their onset and duration

Is pamidronate safe for allergic reactions?

The use of pamidronate may be inadvisable if you have had an allergic reaction to this drug or other medications like it (bisphosphonates) in the past .

How long does it take to take Aredia solution?

How to use Aredia Solution, Reconstituted (Recon Soln) This medication is given by slow injection into a vein for at least 2 hours, but up to 24 hours, or as directed by your doctor. The dosage is based on your medical condition, laboratory tests, and response to treatment. Your doctor will order blood tests to check your kidney function prior ...

How long does it take for a syringe to work?

It may take up to 7 days before the full benefit of this drug takes effect. Tell your doctor if your condition does not improve or if it worsens. Side Effects. Flu -like symptoms (such as mild fever, chills, fatigue, muscle/ joint aches) may occur after treatment.

What is a pamidronate used for?

Pamidronate is used to treat high blood calcium levels and certain bone problems (bone metastases/lesions) that may occur with some types of cancer. It is also used to treat a certain type of bone disease (Paget's disease) that causes abnormal and weak bones.Pamidronate belongs to a class of drugs known as bisphosphonates. It works by slowing the release of calcium from bones to lower blood calcium levels, reducing the risk of broken bones ( fractures) and reducing bone pain.

What to do if side effects persist?

If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

How long does a syringe last?

Most of these effects are mild and can last up to 48 hours. Bone pain, redness/swelling/pain at the infusion site, headache, dizziness, loss of appetite, nausea, vomiting, diarrhea, drowsiness or trouble sleeping may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Where to report side effects?

You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Precautions.

Can you take pamidronate if you are allergic to it?

Before using pamidronate, tell your doctor or pharmacist if you are allergic to it; or other bisphosphonates (such as alendronate ); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Aredia Description

Clinical Pharmacology

Indications and Usage For Aredia

Contraindications

Warnings

Pregnancy: Aredia Should Not Be Used During Pregnancy

Precautions

Adverse Reactions

Overdosage

Dosage and Administration

What Is Aredia?

Warnings

• Clinical Studies
  Transient mild elevation of temperature by at least 1°C was noted 24 to 48 hours after administration of Aredia in 34% of patients in clinical trials. In the saline trial, 18% of patients had a temperature elevation of at least 1°C 24 to 48 hours after treatment. Drug-related local soft-tis…
• Post-Marketing Experience
  The following adverse reactions have been reported in post-marketing use: General: reactivation of Herpes simplex and Herpes zoster, influenza-like symptoms; CNS: confusion and visual hallucinations, sometimes in the presence of electrolyte imbalance; Skin: rash, pruritus; Special …

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Before Taking This Medicine

How Is Aredia given?

Aredia Side Effects

• Aredia is a bisphosphonate (bis FOS fo nayt) medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures. Aredia is used to treat Paget's disease of bone. This medicine is also used to treat high blood levels of calcium caused by cancer (also called hypercalcemiaof malignancy). Aredia i...

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What Other Drugs Will Affect Aredia?

Further Information