Generally, at 2 years, if patients have done well on therapy, and you have 2 years of ongoing disease control, in most patients we are stopping at 2 years and then monitoring them. We'll see increasing numbers of these, but in what we've seen so far, it seems like generally patients continue to do well.
Full Answer
How long does nivolumab (Opdivo) take to work?
Sep 03, 2021 · Median duration of overall survival. Opdivo: 7.5 months (95% CI 5.5, 9.1) at the interim analysis. vs. Docetaxel, methotrexate or Erbitux (cetuximab): 5.1 month (95% CI 4.0, 6.0) Objective response rates were similar between the two treatment groups. Urothelial Carcinoma - locally advanced or metastatic disease.
What is Opdivo and how does it work?
Sep 03, 2021 · Opdivo: 2.1 months (range 1.8-7.4) vs. Investigator’s choice (methotrexate, docetaxel or cetuximab) : 2.0 (range 1.9-4.6) Hepatocellular carcinoma. (CheckMate-040) Opdivo + Yervoy every 3 weeks (4 doses) then Opdivo every 2 weeks (Arm A): 32% (95% CI 20-47): 2.0 months (range 1.3 to 2.7 months) Urothelial carcinoma.
What happens when you stop taking Opdivo?
Jan 23, 2021 · You’ll also need to use effective birth control during treatment and for at least 5 months after your last infusion. Opdivo’s manufacturer hasn’t given recommendations about contraception ...
Is Opdivo a long-term cancer treatment?
• You should use an effective method of birth control during your treatment and for at least 5 months after the last dose of OPDIVO or YERVOY. Talk to your healthcare provider about birth control methods that you can use during this time.
How is OPDIVO different from chemotherapy?
OPDIVO is an immunotherapy treatment. It's a type of medicine that works with your immune system.
How is the OPDIVO + YERVOY® (ipilimumab) combination different from other treatments?
OPDIVO and YERVOY are immunotherapy treatments. Immunotherapies are a type of medicine that work with your immune system to fight cancer.
Where can I go to get my treatments?
You and your doctor should discuss the best place to get your infusions, whether it’s your doctor’s office, an infusion center, or a local hospital.
How do I know if I'm responding to treatment?
While you're undergoing treatment, your doctor will likely order periodic scans to evaluate whether there are any changes in the size of your tumors.
When should I report side effects to my doctor?
Be sure to tell your doctor immediately about all side effects as soon as possible, including any changes in how you are feeling, so he or she can...
Who can I talk to if I need help or have questions?
Talk with your healthcare professional first if you have questions about this treatment option. You can also call a Care Navigator at 1-855-673-486...
How often is Opdivo given?
Opdivo is administered via a 30-60 minute intravenous infusion every 2-4 or 6 weeks.
What is Opdivo used for?
Opdivo (nivolumab) is a monoclonal antibody or type of immunotherapy used to treat a number of different types of cancer. Opdivo is a programmed death-1 (PD-1) inhibitor that helps the T cells of your immune system identify and attack cancer cells. It does this by helping to block the cancer cell’s ability to disguise itself ...
Does immunotherapy work?
Immunotherapy works differently to traditional chemotherapeutics and can take longer to work because once Opdivo starts helping the immune system to uncover the cancer cells , it takes time for the immune system to identify and attack them. During clinical trials of Opdivo researchers measure the ‘time to response’, ...
What is Opdivo used for?
Opdivo (nivolumab) is a brand-name prescription medication used in adults to treat certain types of cancer. These include specific forms of bladder, colorectal, and esophageal cancer, as well as several other cancer types.
What to do if you have a reaction to Opdivo?
If you’re having a severe skin reaction, your healthcare provider will pause or permanently stop your Opdivo infusions.
Does Opdivo cause joint pain?
Joint pain is a common side effect of the drug. Muscle, back, and bone pain are also common side effects of Opdivo. Opdivo can cause your immune system to attack healthy tissues, even after you’ve stopped the drug. This can happen to any part of your body, including your joints.
Can you stop Opdivo?
You should watch for any new or bothersome symptoms on the days between your infusions, too. If you have a severe reaction, your healthcare provider may stop your Opdivo infusion. If you have a mild or moderate reaction during your infusion, they may slow the rate of infusion or pause it to help manage your symptoms.
Can you take Opdivo alone?
However, Opdivo isn’t always used alone to treat melanoma. The risk of side effects may differ depending on your treatment plan. For more information, see the Opdivo Medication Guide. If you’re receiving Opdivo infusions to treat melanoma, ask your doctor about your side effect risks.
Can Opdivo cause hyponatremia?
encephalitis (swelling of your brain) meningitis (swelling of the lining around your brain and spinal cord) diabetic ketoacidosis (dangerously high levels of blood acids called ketones) Also, Opdivo can cause hyponatremia (low blood sodium levels).
Is Opdivo a long term treatment?
Opdivo may be a long-term cancer treatment. Your doctor will decide the length of your treatment based on various factors, including what side effects you experience. Read on to learn more about the possible mild and serious side effects of Opdivo.
What is opdivo used for?
OPDIVO ® (nivolumab) is a prescription medicine used to treat people with cancer of the stomach (gastric), cancer where the esophagus joins the stomach (gastroesophageal junction), and in people with esophageal adenocarcinoma. OPDIVO may be used in combination with chemotherapy that contains fluoropyrimidine and platinum when your cancer cannot be ...
What is nivolumab used for?
OPDIVO ® (nivolumab) is a prescription medicine used to treat people with head and neck cancer (squamous cell carcinoma) that has come back or spread and you have tried chemotherapy that contains platinum and it did not work or is no longer working.
Is OPDivo safe for children?
It is not known if OPDIVO is safe and effective in children younger than 12 years of age with MSI-H or dMMR metastatic colorectal cancer, or in children younger than 18 years of age for the treatment of any other cancers. OPDIVO (10 mg/mL) and YERVOY (5 mg/mL) are injections for intravenous. (IV) use.
Is OPDivo approved for Hodgkin lymphoma?
OPDIVO was approved based on response rate and how long patients’ responses lasted. There is ongoing evaluation of clinical benefit of OPDIVO for this use. For adults with previously treated classical Hodgkin lymphoma including an autologous stem cell transplant whose cancer has come back or spread.
Does opdivo work for bladder cancer?
For people with previously treated advanced bladder cancer (urothelial carcinoma) OPDIVO ® (nivolumab) is a prescription medicine used to treat people with bladder cancer (urothelial carcinoma) that has spread or grown and you have tried chemotherapy that contains platinum, and it did not work or is no longer working.
Is opdivo a prescription?
There is ongoing evaluation of clinical benefit of OPDIVO for this use. OPDIVO ® (nivolumab) is a prescription medicine used in combination with YERVOY ® (ipilimumab) to treat people with liver cancer (hepatocellular carcinoma) if you have previously received treatment with sorafenib. OPDIVO in combination with YERVOY was approved based on response ...
Does opdivo work?
OPDIVO ® (nivolumab) is a prescription medicine used to treat people with a type of advanced stage lung cancer (called non-small cell lung cancer) that has spread or grown and you have tried chemotherapy that contains platinum, and it did not work or is no longer working.