How long can you live with sorafenib?
Median overall survival was 26.1 months with overall 6- and 12-month survival rates of 92.1 and 85%, respectively. Median time to radiological progression was 8 months. The progression-free rate was 64.3%. Fatigue, skin disorders and diarrhea were the most frequent grade 3-4 side effects.
What is the success rate of sorafenib?
The median survival time (MST) for all patients was 11.0 months. The survival rate was significantly higher in the HAIC/sorafenib group than HAIC alone group (MST 22.2 vs 8.7 months, P = 0.017). From administration sorafenib, the disease control rate was 51.8% with MST of 10.4 months.
Can Nexavar cure liver cancer?
NEXAVAR will not cure your cancer, but it has been shown to slow or temporarily stop the growth or spread of certain cancer cells. This is called stable disease.
How effective is Nexavar?
The patients administered with Nexavar showed a 41% reduction in the risk of progression or death when compared to placebo-treated patients. The median PFS was 10.8 months in patients treated with Nexavar, compared to 5.8 months in patients receiving placebo.
What happens when you stop taking sorafenib?
Our results showed that the side effects of sorafenib, such as HFSR, diarrhea and hypertension, resolved after the discontinuation of sorafenib. Weight loss and alopecia also improved gradually.
When should I stop taking sorafenib?
Sorafenib was stopped in cases with severe side effects that recurred and impaired quality of life when reintroducing the dose of 400 mg/day, when toxicity was associated with tumor progression, or when the tumor progressed in the absence of symptomatic progression if a second-line trial was available.
How long does it take for Nexavar to work?
In the study: for at least half of the people taking Nexavar, their cancer didn't progress for at least 10.8 months after starting treatment. for at least half of the people taking a placebo, their cancer didn't progress for at least 5.8 months after starting treatment.
How long can a person live with liver cancer?
Without treatment, the median survival for stage A liver cancer is 3 years. With treatment, between 50 and 70 out of 100 people (between 50 – 70%) will survive for 5 years or more.
Can last stage liver cancer be cured?
Unfortunately when liver cancer is advanced, treatment won't be able to cure it. It aims to control the cancer, relieve symptoms and give you a good quality of life.
Can Nexavar cause kidney failure?
Renal failure was reported in <1% of patients treated with NEXAVAR and 3% of placebo-treated patients.
Is Nexavar a chemotherapy?
Nexavar (Sorafenib) Chemotherapy Drug Information.
What is the cost of Nexavar?
The cost for Nexavar oral tablet 200 mg is around $24,033 for a supply of 120 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. This Nexavar price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
Before Taking This Medicine
You should not use Nexavar if you are allergic to sorafenib, or if you have squamous cell lung cancer and you are being treated with carboplatin (P...
How Should I Take Nexavar?
Nexavar is usually taken 2 times per day. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts...
What Happens If I Miss A Dose?
Take the missed dose as soon as you remember, but at least 2 hours since your last meal. Skip the missed dose if it is almost time for your next sc...
What Other Drugs Will Affect Nexavar?
Tell your doctor about all other cancer medicines you use, especially cisplatin, cyclophosphamide, docetaxel, doxorubicin, fluorouracil, gemcitabin...