How long do you have to take heparin for?
Getting a heparin infusion. The drug heparin is sometimes given as an infusion through an IV line. It is important to have your blood drawn and tested to get the correct amount of heparin in your blood. Your medical team will check to see how well heparin is working with a test called the partial thromboplastin time (PTT).
Can heparin be given through an IV?
Heparin was administered as an initial 5000-U IV bolus, followed by IV infusion of 1000 U/h, adjusted to maintain the aPTT at 1.5 to 2.0 times the control value. Treatment was initiated within 24 hours after the onset of chest pain and continued for ≈6 days.
What is the duration of heparin administration for the treatment of nephrotic syndrome?
Intravenous heparin administered in doses that prolong the activated partial thromboplastin time (APTT) to 1.5 or more times the control value is highly effective, and associated with a low frequency (2%) of recurrent venous thromboembolism. Heparin is continued for 7-10 days, overlapped with warfarin sodium during the last 4-5 days.
What is a heparin infusion for clots?
Jan 16, 2016 · The ACCP recommended duration of overlap was followed in some VTE treatment trials demonstrating similar efficacy of LMWH to heparin (new VTE at 90 days in heparin patients 1.9 and 4.1 %) while others included a 6 day overlap with a single INR requirement above 2.0 (recurrent 90 day VTE in heparin patients 6.8 and 6.9 %) [28, 43–45].
How long does heparin infusion take?
The optimal duration of intravenous heparin treatment is five to seven days because this is the time needed to obtain an adequate and persistent reduction in the vitamin K dependent clotting factors with oral anticoagulants such as warfarin.
How long do you push heparin IV?
Scrub the end of the PICC or Implanted Port line with alcohol pad for 15 seconds. 2. Attach the antibiotic syringe and push the IV medication slowly over 3-5 minutes, or as directed.
Is heparin a continuous infusion?
Continuous Intravenous Infusion Initial Dose 5,000 units by intravenous injection Continuous 20,000 to 40,000 units/24 hours *Based on 150 lb. (68 kg) patient. See full prescribing information for recommended pediatric dosage. Monitoring: Blood coagulation tests guide therapy for full-dose heparin.
When do you stop heparin infusion immediately?
Discontinue heparin infusion 4 – 6 hours prior to surgery or sooner per discretion by surgeon or anti-Xa level < 0.2 unit/mL. b. Re-order heparin 12 – 24 hours after surgery when hemostasis is achieved and there is no evidence of bleeding in consultation with surgeon.
How long does heparin take to dissolve a clot?
It is usually given in the hospital by IV (a small needle inserted in a vein), but it can also be given by an injection under the skin. IV heparin works rapidly; within minutes of receiving it, most patients have excellent anticoagulation that will prevent further clotting.Dec 1, 2008
Do you stop heparin drip to draw PTT?
When we must draw from the arm with fluids infusing, our policy has always been that the RN must pause the IV. If the IV is in the other arm, we do not ask the nurses to pause the infusion no matter what is being infused or what is being drawn.Jun 6, 2017
Is heparin given slowly?
Injected heparin goes into the layer of fat under the skin so that it is released slowly into the body. This type of injection can sometimes cause bruising and pain at the site where the needle goes in.
How long is heparin tubing good for?
Change continuous IV fluids and tubing no more frequently than every 96 hours unless otherwise indicated by the Continuous Infusion Hang Time Grid.Aug 11, 2015
Does heparin drip dissolve clots?
This medicine is sometimes called a blood thinner, although it does not actually thin the blood. Heparin will not dissolve blood clots that have already formed, but it may prevent the clots from becoming larger and causing more serious problems.
What is the most serious potential side effect of heparin therapy?
Thrombocytopenia, heparin-induced thrombocytopenia (HIT) and heparin-induced thrombocytopenia and thrombosis (HITT) are serious side effects of heparin.
What precaution should be taken during heparin therapy?
Stay away from rough sports or other situations where you could be bruised, cut, or injured. Tell your doctor about any falls, blows to the body or head, or other injuries, since serious bleeding may occur inside the body with this medicine. Be careful when using sharp objects, including razors and fingernail clippers.
How long should heparin drip be held before surgery?
Preoperatively, the heparin should be stopped 6 hours before the procedure. Postoperatively, the heparin can be restarted when the surgeon agrees that it is safe, usually 6-12 hours postoperatively.Mar 17, 2022
Description and Brand Names
Heparin injection is an anticoagulant. It is used to decrease the clotting ability of the blood and help prevent harmful clots from forming in blood vessels. This medicine is sometimes called a blood thinner, although it does not actually thin the blood.
Descriptions
Heparin injection is an anticoagulant. It is used to decrease the clotting ability of the blood and help prevent harmful clots from forming in blood vessels. This medicine is sometimes called a blood thinner, although it does not actually thin the blood.
When was heparin first discovered?
Heparin was discovered by McLean in 1916. 15 More than 20 years later, Brinkhous and associates 16 demonstrated that heparin requires a plasma cofactor for its anticoagulant activity; this was named antithrombin III by Abildgaard in 1968 17 but is now referred to simply as antithrombin (AT).
What is a thrombus made of?
Thrombi that form in regions of slow to moderate flow are composed of a mixture of red cells, platelets, and fibrin and are known as mixed platelet-fibrin thrombi. 45 When a platelet-rich arterial thrombus becomes occlusive, stasis occurs, and the thrombus can propagate as a red stasis thrombus.
What causes a stroke in AF patients?
Thromboembolism that originates in the heart can cause embolic stroke and peripheral embolism in patients with atrial fibrillation (AF), acute MI, valvular heart disease, and cardiomyopathy. The second version of “A Guide to Anticoagulant Therapy” was published in 1994.
Is LMWH an anticoagulant?
LMWH has become the anticoagulant of choice for the prevention of venous thrombosis during major orthopedic surgery and in anticoagulant-eligible patients after major trauma. The risk of bleeding with LMWH is small and comparable to that with low-dose heparin.
Does heparin inhibit platelet aggregation?
In vitro, heparin binds to platelets and, depending on the experimental conditions, can either induce or inhibit platelet aggregation. 3839 High-molecular-weight heparin fractions with low affinity for AT have a greater effect on platelet function than LMWH fractions with high AT affinity 40 (Table 1 ).
How long does heparin stay in your system?
Heparin is continued for 7-10 days, overlapped with warfarin sodium during the last 4-5 days. Multiple randomized clinical trials indicate that this approach is highly effective. An alternative approach is to commence heparin and oral anticoagulants together at the time of diagnosis, and to discontinue heparin on the fourth or fifth day. ...
What is the primary objective of heparin therapy?
The primary objective of initial heparin therapy in such patients is to prevent recurrent venous thromboembolism.
What is the treatment for pulmonary embolism?
Heparin therapy for venous thrombosis and pulmonary embolism. Intravenous heparin is the initial treatment of choice for most patients with acute pulmonary embolism or proximal deep vein thrombosis. The primary objective of initial heparin therapy in such patients is to prevent recurrent venous thromboembolism.
Usual Adult Dose for Deep Vein Thrombosis
The manufacturer provides the following dosing guidelines based on clinical experience:#N#Continuous IV infusion:#N#-Initial dose: 5000 units by IV injection#N#-Maintenance dose: 20,000 to 40,000 units per 24 hours by continuous IV infusion#N#Intermittent IV injection:#N#-Initial dose: 10,000 units IV#N#-Maintenance dose: 5000 to 10,000 units IV every 4 to 6 hours#N#Deep subcutaneous (intrafat) injection:#N#333 units/kg subcutaneously followed by 250 units/kg subcutaneously every 12 hours; the following dosage regimen has also been recommended: 5000 units by IV injection followed by 10,000 to 20,000 units subcutaneously, and then 8000 to 10,000 units subcutaneously every 8 hours or 15,000 to 20,000 units subcutaneously every 12 hours.#N#Comments:#N#-Recommended doses are based on a 68 kg patient.#N#-Consult the latest guidelines regarding duration and intensity of anticoagulation for the indicated conditions.#N#-Dosage and administration must be individualized according to the results of suitable laboratory tests.#N#Uses:#N#-Prophylaxis and treatment of venous thrombosis and pulmonary embolism.#N#-Prophylaxis and treatment of thromboembolic complications associated with atrial fibrillation.#N#-Treatment of acute and chronic consumption coagulopathies (disseminated intravascular coagulation).#N#-Prophylaxis and treatment of peripheral arterial embolism.#N#5000 units subcutaneously 2 hours before surgery and 5000 units subcutaneously every 8 to 12 hours thereafter for 7 days or until the patient is ambulatory, whichever is longer.#N#Comments:#N#-Administer by deep subcutaneous (intrafat, e.g., above the iliac crest or abdominal fat layer, arm, or thigh) injection with a fine (25 to 26 gauge) needle to minimize tissue trauma.#N#-Consult the latest guidelines regarding duration and intensity of anticoagulation for the indicated conditions.#N#-Dosage and administration must be individualized according to the results of suitable laboratory tests.#N#Use: Low-dose regimen for prevention of postoperative deep venous thrombosis and pulmonary embolism in patients greater than 40 years old undergoing major abdominothoracic surgery or who, for other reasons, are at risk of developing thromboembolic disease..
Usual Adult Dose for Deep Vein Thrombosis - Prophylaxis
The manufacturer provides the following dosing guidelines based on clinical experience:#N#Continuous IV infusion:#N#-Initial dose: 5000 units by IV injection#N#-Maintenance dose: 20,000 to 40,000 units per 24 hours by continuous IV infusion#N#Intermittent IV injection:#N#-Initial dose: 10,000 units IV#N#-Maintenance dose: 5000 to 10,000 units IV every 4 to 6 hours#N#Deep subcutaneous (intrafat) injection:#N#333 units/kg subcutaneously followed by 250 units/kg subcutaneously every 12 hours; the following dosage regimen has also been recommended: 5000 units by IV injection followed by 10,000 to 20,000 units subcutaneously, and then 8000 to 10,000 units subcutaneously every 8 hours or 15,000 to 20,000 units subcutaneously every 12 hours.#N#Comments:#N#-Recommended doses are based on a 68 kg patient.#N#-Consult the latest guidelines regarding duration and intensity of anticoagulation for the indicated conditions.#N#-Dosage and administration must be individualized according to the results of suitable laboratory tests.#N#Uses:#N#-Prophylaxis and treatment of venous thrombosis and pulmonary embolism.#N#-Prophylaxis and treatment of thromboembolic complications associated with atrial fibrillation.#N#-Treatment of acute and chronic consumption coagulopathies (disseminated intravascular coagulation).#N#-Prophylaxis and treatment of peripheral arterial embolism.#N#5000 units subcutaneously 2 hours before surgery and 5000 units subcutaneously every 8 to 12 hours thereafter for 7 days or until the patient is ambulatory, whichever is longer.#N#Comments:#N#-Administer by deep subcutaneous (intrafat, e.g., above the iliac crest or abdominal fat layer, arm, or thigh) injection with a fine (25 to 26 gauge) needle to minimize tissue trauma.#N#-Consult the latest guidelines regarding duration and intensity of anticoagulation for the indicated conditions.#N#-Dosage and administration must be individualized according to the results of suitable laboratory tests.#N#Use: Low-dose regimen for prevention of postoperative deep venous thrombosis and pulmonary embolism in patients greater than 40 years old undergoing major abdominothoracic surgery or who, for other reasons, are at risk of developing thromboembolic disease..
Usual Adult Dose for Prevention of Thromboembolism in Atrial Fibrillation
The manufacturer provides the following dosing guidelines based on clinical experience:#N#Continuous IV infusion:#N#-Initial dose: 5000 units by IV injection#N#-Maintenance dose: 20,000 to 40,000 units per 24 hours by continuous IV infusion#N#Intermittent IV injection:#N#-Initial dose: 10,000 units IV#N#-Maintenance dose: 5000 to 10,000 units IV every 4 to 6 hours#N#Deep subcutaneous (intrafat) injection:#N#333 units/kg subcutaneously followed by 250 units/kg subcutaneously every 12 hours; the following dosage regimen has also been recommended: 5000 units by IV injection followed by 10,000 to 20,000 units subcutaneously, and then 8000 to 10,000 units subcutaneously every 8 hours or 15,000 to 20,000 units subcutaneously every 12 hours.#N#Comments:#N#-Recommended doses are based on a 68 kg patient.#N#-Consult the latest guidelines regarding duration and intensity of anticoagulation for the indicated conditions.#N#-Dosage and administration must be individualized according to the results of suitable laboratory tests.#N#Uses:#N#-Prophylaxis and treatment of venous thrombosis and pulmonary embolism.#N#-Prophylaxis and treatment of thromboembolic complications associated with atrial fibrillation.#N#-Treatment of acute and chronic consumption coagulopathies (disseminated intravascular coagulation).#N#-Prophylaxis and treatment of peripheral arterial embolism.#N#5000 units subcutaneously 2 hours before surgery and 5000 units subcutaneously every 8 to 12 hours thereafter for 7 days or until the patient is ambulatory, whichever is longer.#N#Comments:#N#-Administer by deep subcutaneous (intrafat, e.g., above the iliac crest or abdominal fat layer, arm, or thigh) injection with a fine (25 to 26 gauge) needle to minimize tissue trauma.#N#-Consult the latest guidelines regarding duration and intensity of anticoagulation for the indicated conditions.#N#-Dosage and administration must be individualized according to the results of suitable laboratory tests.#N#Use: Low-dose regimen for prevention of postoperative deep venous thrombosis and pulmonary embolism in patients greater than 40 years old undergoing major abdominothoracic surgery or who, for other reasons, are at risk of developing thromboembolic disease..
Usual Adult Dose for Pulmonary Embolism
The manufacturer provides the following dosing guidelines based on clinical experience:#N#Continuous IV infusion:#N#-Initial dose: 5000 units by IV injection#N#-Maintenance dose: 20,000 to 40,000 units per 24 hours by continuous IV infusion#N#Intermittent IV injection:#N#-Initial dose: 10,000 units IV#N#-Maintenance dose: 5000 to 10,000 units IV every 4 to 6 hours#N#Deep subcutaneous (intrafat) injection:#N#333 units/kg subcutaneously followed by 250 units/kg subcutaneously every 12 hours; the following dosage regimen has also been recommended: 5000 units by IV injection followed by 10,000 to 20,000 units subcutaneously, and then 8000 to 10,000 units subcutaneously every 8 hours or 15,000 to 20,000 units subcutaneously every 12 hours.#N#Comments:#N#-Recommended doses are based on a 68 kg patient.#N#-Consult the latest guidelines regarding duration and intensity of anticoagulation for the indicated conditions.#N#-Dosage and administration must be individualized according to the results of suitable laboratory tests.#N#Uses:#N#-Prophylaxis and treatment of venous thrombosis and pulmonary embolism.#N#-Prophylaxis and treatment of thromboembolic complications associated with atrial fibrillation.#N#-Treatment of acute and chronic consumption coagulopathies (disseminated intravascular coagulation).#N#-Prophylaxis and treatment of peripheral arterial embolism.#N#5000 units subcutaneously 2 hours before surgery and 5000 units subcutaneously every 8 to 12 hours thereafter for 7 days or until the patient is ambulatory, whichever is longer.#N#Comments:#N#-Administer by deep subcutaneous (intrafat, e.g., above the iliac crest or abdominal fat layer, arm, or thigh) injection with a fine (25 to 26 gauge) needle to minimize tissue trauma.#N#-Consult the latest guidelines regarding duration and intensity of anticoagulation for the indicated conditions.#N#-Dosage and administration must be individualized according to the results of suitable laboratory tests.#N#Use: Low-dose regimen for prevention of postoperative deep venous thrombosis and pulmonary embolism in patients greater than 40 years old undergoing major abdominothoracic surgery or who, for other reasons, are at risk of developing thromboembolic disease..
Usual Adult Dose for Disseminated Intravascular Coagulation
The manufacturer provides the following dosing guidelines based on clinical experience:#N#Continuous IV infusion:#N#-Initial dose: 5000 units by IV injection#N#-Maintenance dose: 20,000 to 40,000 units per 24 hours by continuous IV infusion#N#Intermittent IV injection:#N#-Initial dose: 10,000 units IV#N#-Maintenance dose: 5000 to 10,000 units IV every 4 to 6 hours#N#Deep subcutaneous (intrafat) injection:#N#333 units/kg subcutaneously followed by 250 units/kg subcutaneously every 12 hours; the following dosage regimen has also been recommended: 5000 units by IV injection followed by 10,000 to 20,000 units subcutaneously, and then 8000 to 10,000 units subcutaneously every 8 hours or 15,000 to 20,000 units subcutaneously every 12 hours.#N#Comments:#N#-Recommended doses are based on a 68 kg patient.#N#-Consult the latest guidelines regarding duration and intensity of anticoagulation for the indicated conditions.#N#-Dosage and administration must be individualized according to the results of suitable laboratory tests.#N#Uses:#N#-Prophylaxis and treatment of venous thrombosis and pulmonary embolism.#N#-Prophylaxis and treatment of thromboembolic complications associated with atrial fibrillation.#N#-Treatment of acute and chronic consumption coagulopathies (disseminated intravascular coagulation).#N#-Prophylaxis and treatment of peripheral arterial embolism.#N#5000 units subcutaneously 2 hours before surgery and 5000 units subcutaneously every 8 to 12 hours thereafter for 7 days or until the patient is ambulatory, whichever is longer.#N#Comments:#N#-Administer by deep subcutaneous (intrafat, e.g., above the iliac crest or abdominal fat layer, arm, or thigh) injection with a fine (25 to 26 gauge) needle to minimize tissue trauma.#N#-Consult the latest guidelines regarding duration and intensity of anticoagulation for the indicated conditions.#N#-Dosage and administration must be individualized according to the results of suitable laboratory tests.#N#Use: Low-dose regimen for prevention of postoperative deep venous thrombosis and pulmonary embolism in patients greater than 40 years old undergoing major abdominothoracic surgery or who, for other reasons, are at risk of developing thromboembolic disease..
Usual Adult Dose for Venous Thromboembolism
The manufacturer provides the following dosing guidelines based on clinical experience:#N#Continuous IV infusion:#N#-Initial dose: 5000 units by IV injection#N#-Maintenance dose: 20,000 to 40,000 units per 24 hours by continuous IV infusion#N#Intermittent IV injection:#N#-Initial dose: 10,000 units IV#N#-Maintenance dose: 5000 to 10,000 units IV every 4 to 6 hours#N#Deep subcutaneous (intrafat) injection:#N#333 units/kg subcutaneously followed by 250 units/kg subcutaneously every 12 hours; the following dosage regimen has also been recommended: 5000 units by IV injection followed by 10,000 to 20,000 units subcutaneously, and then 8000 to 10,000 units subcutaneously every 8 hours or 15,000 to 20,000 units subcutaneously every 12 hours.#N#Comments:#N#-Recommended doses are based on a 68 kg patient.#N#-Consult the latest guidelines regarding duration and intensity of anticoagulation for the indicated conditions.#N#-Dosage and administration must be individualized according to the results of suitable laboratory tests.#N#Uses:#N#-Prophylaxis and treatment of venous thrombosis and pulmonary embolism.#N#-Prophylaxis and treatment of thromboembolic complications associated with atrial fibrillation.#N#-Treatment of acute and chronic consumption coagulopathies (disseminated intravascular coagulation).#N#-Prophylaxis and treatment of peripheral arterial embolism.#N#5000 units subcutaneously 2 hours before surgery and 5000 units subcutaneously every 8 to 12 hours thereafter for 7 days or until the patient is ambulatory, whichever is longer.#N#Comments:#N#-Administer by deep subcutaneous (intrafat, e.g., above the iliac crest or abdominal fat layer, arm, or thigh) injection with a fine (25 to 26 gauge) needle to minimize tissue trauma.#N#-Consult the latest guidelines regarding duration and intensity of anticoagulation for the indicated conditions.#N#-Dosage and administration must be individualized according to the results of suitable laboratory tests.#N#Use: Low-dose regimen for prevention of postoperative deep venous thrombosis and pulmonary embolism in patients greater than 40 years old undergoing major abdominothoracic surgery or who, for other reasons, are at risk of developing thromboembolic disease..
Usual Adult Dose for Cardiothoracic Surgery
Initial dose: At least 150 units/kg; frequently, 300 units/kg is used for procedures estimated to last less than 60 minutes or 400 units/kg for those estimated to last longer than 60 minutes.#N#Comments:#N#-Consult the latest guidelines regarding duration and intensity of anticoagulation for the indicated conditions.#N#-Dosage and administration must be individualized according to the results of suitable laboratory tests.#N#Uses:#N#-Prevention of clotting in arterial and cardiac surgery.#N#-Total body perfusion for open-heart surgery..
What are the side effects of heparin?
The main side effect of heparin is bleeding. For this reason, it is important that physicians track blood counts when people are being treated with intravenous heparin in order to ensure that blood counts remain stable. Spontaneous bleeding can occur from several places in the body, including: 1 1 Open wounds or surgical sites 2 Stomach and intestines 3 Uterus and ovaries 4 Gums and mouth
Why is heparin used in hospitals?
Use in the Hospital. Heparin prevents the formation of blood clots. Some of the most common reasons heparin is used include: 1 . To prevent the formation of the blood clots that can form as a complication of staying in bed for prolonged periods of time: A low daily dose of heparin is typically injected under the skin to help prevent ...
What does a carotid doppler show?
When a carotid doppler test suggests that a blood clot is located inside the carotid artery, or an echocardiogram shows a blood clot inside the heart.
What is heparin 2021?
Updated on January 11, 2021. Heparin is a blood thinning medication used to prevent blood clot formation. Heparin can be given either directly into the bloodstream or as an injection under the skin. No oral form of heparin is available, and that is why it is typically used in the hospital setting. Dana Neely / Taxi / Getty Images.
How long does it take for coumadin to work?
This is done because Coumadin can take up to 72 hours before its desired effect is reached.
What is the PTT for heparin?
Unlike most medications, the dose of heparin must be chosen according to the results of a blood test called the partial thromboplastin time (PTT).
Does heparin cause thrombocytopenia?
Another important side effect of heparin is a condition known as heparin-induced thrombocytopenia (HIT). In this condition, heparin induces the body's immune system to develop antibodies against its own platelets.
How long does heparin last?
Heparin is generally continued for seven to ten days. During this time warfarin is generally begun, and it is important to continue the patient on warfarin for five to seven days while the patient is receiving intravenous heparin therapy.
Is heparin effective for pulmonary embolism?
It has been shown that in many cases, low-dose heparin is effective in the prevention of both venous thrombosis and pulmonary embolism. However, once venous thrombosis has already occurred, it is necessary to use full-dose heparin, preferably by the continuous intravenous route, with maintenance of the partial thromboplastin time (PTT) ...
What does it feel like to have an injection?
chills or fever. fast or irregular breathing . irritation, pain, redness, or ulcers at the place of injection. itching and burning feeling, especially on the bottom of the feet. nausea or vomiting. numbness or tingling in the hands or feet. pain, coldness, or blue color of the skin on the arms or legs.
What does it mean when your arm is blue?
pain, coldness, or blue color of the skin on the arms or legs. peeling of the skin. puffiness or swelling of the eyelids or around the eyes. shortness of breath. skin color change, especially near the place of injection or in the fingers, toes, arms, or legs. skin rash, hives, or itching.
What are the symptoms of a swollen stomach?
Abdominal or stomach pain or swelling. back pain or backaches. bleeding from the gums when brushing teeth. blood in the urine. constipation. coughing up blood. dizziness. headaches, severe or continuing. heavy bleeding or oozing from cuts or wounds.
Can medicine cause side effects?
Side Effects. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor or nurse immediately if any of the following side effects occur:
What are the side effects of a syringe?
Side effects requiring immediate medical attention 1 Abdominal or stomach pain or swelling 2 back pain or backaches 3 bleeding from the gums when brushing teeth 4 blood in the urine 5 constipation 6 coughing up blood 7 dizziness 8 headaches, severe or continuing 9 heavy bleeding or oozing from cuts or wounds 10 joint pain, stiffness, or swelling 11 menstrual bleeding, unexpected or unusually heavy 12 unexplained bruising or purplish areas on the skin 13 unexplained nosebleeds 14 vomiting of blood or material that looks like coffee grounds
What happens if you stop taking a syringe?
skin color change, especially near the place of injection or in the fingers, toes, arms, or legs. skin rash, hives, or itching. tearing of the eyes. tightness in the chest. trouble with breathing. wheezing. After you stop using this medicine, it may still produce some side effects that need attention.
Does heparin cause side effects?
Side effects requiring immediate medical attention. Along with its needed effects, heparin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
What does it feel like to have an injection?
chills or fever. fast or irregular breathing . irritation, pain, redness, or ulcers at the place of injection. itching and burning feeling, especially on the bottom of the feet. nausea or vomiting. numbness or tingling in the hands or feet. pain, coldness, or blue color of the skin on the arms or legs.
What are the symptoms of a swollen back?
back pain or backaches. bleeding from the gums when brushing teeth. blood in the urine. constipation. coughing up blood. dizziness. headaches, severe or continuing. heavy bleeding or oozing from cuts or wounds. joint pain, stiffness, or swelling.
