Treatment FAQ

how is bismuth used in cancer treatment

by Mrs. Caitlyn Farrell II Published 2 years ago Updated 2 years ago
image

Bismuth complexes have been widely used in biomedicine with satisfactory therapeutic effects, mostly in Helicobacter pylori

Helicobacter pylori

Helicobacter pylori, previously known as Campylobacter pylori, is a Gram-negative, microaerophilic bacterium usually found in the stomach. It was identified in 1982 by Australian scientists Barry Marshall and Robin Warren, who found that it was present in a person with chronic gastritis and gastric ulcers, conditions not previously believed to have a microbial cause. It is also linked to the developme…

eradication, but also as potential antimicrobial and anti-leishmanial agents. Additionally, in recent years, application of bismuth-based compounds as potent anticancer drugs has been studied extensively.

Cell membrane modification and dissolution of bismuth nanoparticles in body allow the fine tune of the circulation, radiation enhancement and body clearance in such a way that treatment effect can be maximized and long term toxicity can be minimized.

Full Answer

What is bismuth used for?

Bismuth (Bi) is a chemical element with the atomic number 83. Bismuth supplements usually contain bismuth in a salt form, such as bismuth subsalicylate. Bismuth salts seem to help eliminate bacteria that cause stomach problems such as diarrhea and stomach ulcers. Bismuth salts also work like an antacid to treat problems such as indigestion.

Does bismuth help with diarrhea in cancer patients?

Early research suggests that taking bismuth at the same time as very high doses of cancer drugs can reduce how long diarrhea lasts in people being treated for lymphoma. But it doesn't seem to help with diarrhea in people receiving cancer drugs for multiple myeloma.

What are the side effects of bismuth supplements?

Allergy to salicylate: Many bismuth supplements contain the bismuth salt called bismuth subsalicylate. When taken by mouth, bismuth subsalicylate breaks down in the stomach to form bismuth and salicylate. In theory, people who are sensitive to salicylate might have a serious side effect to these supplements

Is it safe to take bismuth with antibiotics?

But taking bismuth with antibiotics might cause more side effects. Bismuth salts have also been taken in combination with antibiotics and medications that decrease stomach acid (proton pump inhibitors). Research shows that this combination treats H. pylori infections as well as most other antibiotic combination therapies.

image

Which element is used in cancer treatment?

Cobalt therapy or cobalt -60 therapy is the medical use of gamma rays from the radioisotope cobalt -60 to treat conditions such as cancer.

Which metal is used in cancer treatment?

Platinum drugs, such as cisplatin, carboplatin and oxaliplatin, are the mainstay of the metal-based compounds in the treatment of cancer, but the delay in the therapeutic accomplishment of other metal-based compounds hampered the progress of research in this field.

How is bismuth 213 used in medicine?

Bismuth-213 | Encyclopedia MDPI. In contrast to external high energy photon or proton therapy, targeted radionuclide therapy (TRNT) is a systemic cancer treatment allowing targeted irradiation of a primary tumor and all its metastases, resulting in less collateral damage to normal tissues.

Which isotope helps in treatment of cancer?

Cobalt-60 is most commonly used.

Which compounds are used for chemotherapy in cancer treatment?

Examples of alkylating agents include:Altretamine.Bendamustine.Busulfan.Carboplatin.Carmustine.Chlorambucil.Cisplatin.Cyclophosphamide.More items...•

Which non metal is used in cancer therapy?

Radon is the non-metal that is used for cancer therapy.

What is the use of bismuth?

Bismuth finds its main uses in pharmaceuticals, atomic fire alarms and sprinkler systems, solders and other alloys and pigments for cosmetics, glass and ceramics. It is also used as a catalyst in rubber production.

How is bismuth-213 produced?

Bismuth-213 is normally produced as a daughter product of 229Th (t1/2 = 7340 yr). The radioactive decay chain in which 213Bi is found is well-known (Figure 1): 233U (t1/2 = 1.62 × 105 yr) → 229Th → 225Ra (t1/2 = 14.8 days) → 225Ac (t1/2 = 10 days) → 213Bi (t1/2 = 45.6 min).

What is the half life of bismuth-213?

However, the half-life of 213Bi is sufficiently long (46 min) for significant translocation to occur prior to its decay.

Why are isotopes used in cancer treatment?

Radioisotope therapy is a procedure in which a liquid form of radiation is administered internally through infusion or injection. RIT's ultimate purpose is to treat cancerous cells with minimal damage to the normal surrounding tissue. These therapies are not normally the first approach used to fight a patient's cancer.

What isotope is used for radiation therapy?

By implanting radioactive sources directly into the tumor it is possible to deliver high-dose radiation to small tumors. The isotopes most commonly used in IRT are iridium-192 or iodine-125. Iridium (half-life 74 days), usually in the form of a wire, is used as a removable source.

What element is used in radiotherapy?

Because of this, radioactive iodine (also called radioiodine or iodine-131) can be used to destroy the thyroid gland and thyroid cancer with little effect on the rest of the body. This treatment is often used after thyroid cancer surgery to destroy any thyroid cells left behind.

Brand Names: US

Bismatrol Maximum Strength [OTC] [DSC]; Bismatrol [OTC]; Diotame InstyDose [OTC]; Geri-Pectate [OTC]; GoodSense Stomach Relief [OTC]; Kao-Tin [OTC] [DSC]; Peptic Relief [OTC] [DSC]; Pepto-Bismol InstaCool [OTC] [DSC]; Pepto-Bismol To-Go [OTC]; Pepto-Bismol [OTC]; Pink Bismuth [OTC]; Stomach Relief Extra Strength [OTC]; Stomach Relief Plus [OTC]; Stomach Relief [OTC].

What do I need to tell my doctor BEFORE I take this drug?

If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.

What are some things I need to know or do while I take this drug?

Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

How is this drug best taken?

Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.

What do I do if I miss a dose?

If you take this drug on a regular basis, take a missed dose as soon as you think about it.

How long does bismuth salt help with bowel disease?

. Early research shows that taking a certain bismuth salt three times daily for 8 weeks decreases stool frequency in people with microscopic colitis. Minor bleeding.

What is the atomic number of bismuth?

Overview. Bismuth (Bi) is a chemical element with the atomic number 83 . Supplements containing bismuth usually contain bismuth as a salt. Bismuth salts are most commonly used for travelers' diarrhea, a digestive tract infection that can lead to ulcers ( Helicobacter pylori or H. pylori), and stomach ulcers.

How much bismuth subcitrate is needed for ulcers?

pylori): As a triple therapy, 120 mg bismuth subcitrate, 500 mg amoxicillin, and 250 mg metronidazole four times daily for 14 days have been used.

How long is bismuth salt good for?

Bismuth salts, including ranitidine bismuth citrate, colloidal bismuth subcitrate, and bismuth subnitrate appear to be safe when taken in doses of 400-2100 mg daily for up to 56 days.

How long does bismuth subsalicylate last?

Research shows that taking bismuth subsalicylate the day before traveling and continuing until 2 days after returning home reduces the chance of getting travelers' diarrhea by up to 41%.

Does bismuth help with oral mucositis?

Swelling ( inflammation) and sores inside the mouth (oral mucositis). Early research suggests that taking bismuth at the same time as very high dos es of cancer drugs can prevent oral mucositis in people being treated for multiple myeloma.

Is bismuth safe to take?

Bismuth is POSSIBLY UNSAFE when taken by mouth in large amounts due to the risk for kidney failure, and when taken over the long-term due to the risk of nerve damage. When applied to the skin: There isn't enough reliable information to know if bismuth is safe or what the side effects might be .

What is the best herb for cancer?

It has been shown to be effective against cancer tumours, and can shrink them; it is one of the herbs in an anti-cancer poultice called Black Salve against breast and skin cancers; and has proven useful with sarcomas. 4 BUTCHERS BROOM (Ruscus aculeatus): The ...

Does a chaparral reduce cancer?

Research indicates it can reduce tumour size, particularly with skin cancers. It also helps reduce the side-effects of chemo and radiotherapy. 6 CHAPARRAL (Larrea mexicana): Cancer Watch covered a major research study from the US which heaped praise on this herb.

Does Berberine help with cancer?

Research has shown these herbs to have a strong action against cancer and they have been used with many cancers, especially Ovarian cancer. In Cancer Watch March 2015, an ingredient Berberine, was shown in research to outperform brain cancer drug, Temozolomide in vitro. It was also shown to act synergistically with it and improve its efficacy.

Can quinoids help with cancer?

That alone might be enough to eradicate cancer drivers. But new research on the differing ingredients has shown the quinoids possess immune strengthening abilities and seem to help in cases of blood and lymph cancers.

Does astragalus help with cancer?

The MD Anderson Cancer Centre in Texas conducted research showing that taking Astragalus when having Radiotherapy doubled survival times. 2 BERBERIS FAMILY (e.g. Podophyllum peltanum): Slow active purgative. Research has shown these herbs to have a strong action against cancer and they have been used with many cancers, especially Ovarian cancer.

Does milk thistle help with chemo?

12 MILK THISTLE: Known for years to be helpful in strengthening the liver, this herb has now been shown to be capable of protecting the liver during chemotherapy. Research in America showed that leukaemia patients who took milk thistle had reduced liver toxicity and chemo side-effects.

Can goldeneal be used for cancer?

But then, the FDA has never approved a herb for use as a cancer treatment. 11 GOLDENSEAL: One cause of stomach cancer can be the bacterium Helicobacter pylori. This burrows into the mucous lining of the stomach to hide from gastric acids, and then causes irritation, acid reflux, ulcers and even cancer.

image
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 1 2 3 4 5 6 7 8 9