Treatment FAQ

how does radioactive iodine treatment work

by Ms. Chasity Dach IV Published 2 years ago Updated 2 years ago
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The radioactive iodine treatment uses pellets of radioactive iodine about the size of a grain of rice, and it involves an operation. Your surgeon will put the pellets into the prostate, where they attack the disease by giving off radiation for weeks or months.

Radioactive iodine is an effective type of treatment for cancer of the thyroid gland. This is because the radioactive iodine from the drink or capsule is absorbed into your body and picked up by the thyroid cancer cells, even if they have spread to other parts of the body. The radiation then destroys the cancer cells.

Full Answer

What are the side effects of radioactive iodine therapy?

Temporary side effects of RAI may include:

  • Neck tenderness and swelling.
  • Nausea.
  • Swollen salivary glands.
  • Loss of taste or taste change.
  • Dry mouth/insufficient salivary production.
  • Dry eyes.
  • Excessive tearing from the eyes.

What are the long term effects of radioactive iodine?

After radioactive iodine treatment for thyroid cancer

  • Thyroid medicine after radioactive iodine treatment. You may have stopped taking your thyroid hormone tablets in preparation for your treatment. ...
  • Radiation safety precautions. ...
  • Travelling after radioactive iodine treatment. ...
  • Possible short term side effects. ...
  • Possible long term side effects
  • Further radioactive iodine treatments. ...

What to expect after radioactive iodine treatment?

You can expect to live a fairly normal life after radioactive iodine treatment but your life will probably not be exactly as it was before your procedure. For most people, this means that you can expect to live at 80-90% of your 'normal'.

What are the risks of radioactive iodine treatment?

  • Stay at least six feet away from other people, including members of the public, family members, and co-workers, for three to 11 days. ...
  • Sleep apart from adults by at least six feet (a separate bedroom is recommended) and avoid sexual activity.
  • Avoid sleeping in the same bed with a pregnant woman, infant, or child for a period of six to 23 days. ...

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How long do you have to be in isolation after radioactive iodine?

You are also required to self isolate for 7 days after your radioiodine treatment in order to minimise the risk of contracting COVID-19 whilst there is still a large amount of radioactivity in your body. A small proportion of people with COVID-19 may become very unwell and require admission to hospital.

How long does it take for radioactive iodine treatment to work?

Although the radioactivity remains in the thyroid for some time, it is greatly diminished within a few days. The effect of this treatment on the thyroid gland usually takes between one and three months to develop. Maximum benefit occurs three to six months after treatment.

What happens to your body after radioactive iodine treatment?

A swollen or tender neck and feeling flushed Some people may have a feeling of tightness or swelling in their neck for a few days after treatment. This is more common if you still had a large part of your thyroid gland when you have radioactive iodine treatment. Some people also feel flushed.

Does radioactive iodine shorten your life?

Quality of life is worse at 6-10 years after radioactive iodine therapy of Graves' disease compared with treatment with antithyroid drugs or surgery. Quality of life is worse at 6-10 years after radioactive iodine therapy of Graves' disease compared with treatment with antithyroid drugs or surgery.

What are the long-term side effects of radioactive iodine?

NCI study finds long-term increased risk of cancer death following common treatment for hyperthyroidism. New study findings show an association between the dose of a common treatment for hyperthyroidism and risk of death from solid cancers.

Do you lose your hair with radioactive iodine treatment?

Radioiodine does not cause hair loss.

Will I gain weight after radioactive iodine treatment?

Treatment of hyperthyroidism with RAI or anti-thyroid medications is associated with an increased risk of gaining weight and even developing obesity. This risk is slightly higher with RAI therapy compared to medications.

Can a thyroid grow back after radioactive iodine?

Once hypothyroidism has been achieved, it is usually irreversible with the patient requiring lifelong thyroid replacement. Recurrence of hyperthyroidism after RAI therapy may be due to inadequate dosing or early Marine Lenhart syndrome.

Which is better thyroid surgery or radioactive iodine?

Surgery for hyperthyroidism was associated with a lower risk of all-cause and cardiovascular death as compared to radioactive iodine therapy during long-term follow-up, particularly in men.

Does radioactive iodine affect teeth?

High-dose radioiodine treatment can impair the long-term dental health, depending on the intensity of treatment and individual radioiodine uptake within the salivary glands. Patients should be made aware of salivary gland damage before high-dose radioiodine treatment.

Is there an alternative to radioactive iodine?

These alternative therapies include two major categories: redifferentiation therapy and recent molecular target therapy. Several clinical trials have investigated these therapies. They demonstrated potential effects of the therapies, although the results have been somewhat limited so far.

How does no thyroid affect the body?

If you don't have enough thyroid hormone, your body processes slow down. That means your body makes less energy, and your metabolism becomes sluggish.

What is the radiation used for thyroid cancer?

The radiation dose used here is much stronger than the one used in radioiodine scans, which are described in Tests for Thyroid Cancer. This treatment can be used to ablate (destroy) any thyroid tissue not removed by surgery or to treat some types of thyroid cancer that have spread to lymph nodes and other parts of the body.

How long after radiation therapy can you go home?

Depending on the dose of radioiodine used and where you are being treated, you might need to be in the hospital for a few days after treatment, staying in a special isolation room to prevent others from being exposed to radiation. Some people may not need to be hospitalized. Once you are allowed to go home after treatment, you will be given instructions on how to protect others from radiation exposure and how long you need to take these precautions. These instructions may vary slightly by treatment center. Be sure you understand the instructions before you leave the hospital.

How long should I take thyrotropin before RAI?

Another way is to get an injection (shot) of thyrotropin (Thyrogen), which can make withholding thyroid hormone for a long period of time unnecessary. This drug is given daily for 2 days, followed by RAI on the 3 rd day. Most doctors also recommend that you follow a low iodine diet for 1 or 2 weeks before treatment.

How to treat RAI?

For RAI therapy to be most effective, you must have a high level of thyroid-stimulating hormone (TSH or thyrotropin) in the blood. This hormone is what makes thyroid tissue (and cancer cells) take up radioactive iodine. If your thyroid has been removed, there are a couple of ways to raise TSH levels before being treated with RAI: 1 One way is to stop taking thyroid hormone pills for several weeks. This causes very low thyroid hormone levels (hypothyroidism), which makes the pituitary gland to release more TSH. This intentional hypothyroidism is temporary, but it often causes symptoms like tiredness, depression, weight gain, constipation, muscle aches, and reduced concentration. 2 Another way is to get an injection (shot) of thyrotropin (Thyrogen), which can make withholding thyroid hormone for a long period of time unnecessary. This drug is given daily for 2 days, followed by RAI on the 3 rd day.

What to do if you have any questions about the possible risks and benefits of your treatment?

Talk to your health care team if you have any questions about the possible risks and benefits of your treatment.

Can you use rai for thyroid cancer?

Discuss your risks and benefits of RAI therapy with your doctor. Radioactive iodine therapy cannot be used to treat anaplastic (undifferentiated) and medullary thyroid carcinomas because these types of cancer do not take up iodine.

Can radiation cause irregular periods?

Radioactive iodine may also affect a woman’ s ovaries, and some women may have irregular periods for up to a year after treatment.

How long does it take for thyroid to stop taking up radioactive iodine?

If you have too much iodine in your diet, it can stop the thyroid cells from taking up the radioactive iodine. Continue to follow this diet for 24 hours after your treatment is completed, or as instructed by your doctor. Read the resource for more information.

Where does radioactive iodine leave the body?

Most of the extra radioactive iodine will leave your body through your urine (pee), and smaller amounts will leave your body in your saliva (spit), sweat, and bowel movements (poop).

What is the name of the service that takes up thyroid cells?

If you do, tell your doctor in Molecular Imaging and Therapy Service (MITS) before your treatment. This is sometimes called the Nuclear Medicine service. Radioactive iodine enters your bloodstream and is taken up by any thyroid- like cells. The radioactivity destroys the cancer cells.

How long after radioactive iodine therapy can you get pregnant?

Pregnancy and radioactive iodine therapy. Don’t get pregnant or get your partner pregnant for at least 6 months after getting radioactive iodine therapy, or as long as your doctor tells you to. Use birth control after treatment for at least 6 months after getting this treatment.

How to treat thyrotropin alfa?

Your treatment plan will follow these steps that will take place over a few days: 1. On the first day, you’ll have blood tests. After those tests, you’ll see your doctor and get a thyrotropin alfa (Thyrogen ®) injection (shot) to help you get ready for your treatment.

How long does it take for thyroid pain to go away?

This is temporary and usually goes away within 8 weeks after your treatment. Try foods with different flavors to make sure you get the nutrition you need. Discomfort in your neck. This can happen during the first 2 to 3 weeks after your treatment, but it depends on the amount of thyroid tissue still in your neck.

Why does my mouth dry out after iodine?

Dry mouth. This is also caused by irritation or damage to your salivary glands. Dry mouth may happen if you’re taking a higher dose of radioactive iodine. Dry mouth can happen right after treatment, or it may happen for several months to a year after treatment.

What is iodine used for?

Iodine, in the form of iodide, is made into two radioactive forms of iodine that are commonly used in patients with thyroid diseases: I-123 ( harmless to thyroid cells) and I-131 ( destroys thyroid cells ). The radiation emitted by each of these forms of iodine can be detected from outside the patient to gain information about thyroid function ...

Why is iodine important for the thyroid gland?

Iodine is essential for proper function of the thyroid gland, which use s it to make the thyroid hormones. The thyroid is equipped with an active system or “pump” for moving iodine into its cells, where it is concentrated as iodide. The thyroid gland is the only tissue in the body that takes up and holds onto iodine.

What is the I-131 thyroid?

THYROID TISSUE – I-131 is given to destroy overactive thyroid tissue (see Hyperthyroidism brochure) or to shrink thyroid glands that are functioning normally but are causing problems because of their size (see Goiter brochure ). Patients are asked to follow some radiation precautions after treatment in order to limit radiation exposure to others (see chart). I-131 may occasionally cause mild pain in the neck that can be treated with aspirin, ibuprofen or acetaminophen. The RAI treatment may take up to several months to have its effect. Frequently, the end result of RAI treatment of hyperthyroidism is hypothyroidism, which is treated by thyroid hormone replacement (see Hypothyroidism brochure ).

What is the I-123 isotope used for?

I-123 is the usual isotope used to take pictures and determine the activity of the intact thyroid gland ( Thyroid Scan and Radioactive Iodine Uptake, RAIU ), since it is harmless to thyroid cells. No special radiation precautions are necessary after a thyroid scan or RAIU using I-123. I-131 can also be used to take pictures of the thyroid gland, ...

How does I-131 work?

This is performed after the remaining thyroid cells ( including any cancer cells) are stimulated by raising TSH levels by either withdrawing the thyroid hormone pills or by treating with recombinant human TSH. Patients are asked to follow some radiation precautions after treatment in order to limit radiation exposure to others ( see below ). Depending on state regulations, patients may have to stay isolated in the hospital for about 24 hours to avoid exposing other people to radiation, especially if there are young children living in the same home.

Is 131-I radiation safe?

Although the treatments with 131-I are generally safe, RAI produces radiation so patients must do their best to avoid radiation exposure to others, particularly to pregnant women and young children. The amount of radiation exposure markedly decreases as the distance from the patient increases. Patients who need to travel in the days after I-131 RAI treatment are advised to carry a letter of explanation from their physician. This is because radiation detection devices used at airports or in federal buildings may pick up even very small radiation levels. Details should be discussed with a physician prior to, and at the time of, the RAI treatment.

When can you stop breast feeding after I-131?

This protects the baby who would otherwise receive radioactive milk and the mother’s breasts which concentrate RAI. Breastfeeding must be stopped at least 6 weeks before administration of I-131 treatment and should not be restarted after administration of RAI, but can be safely done after future pregnancies.

What is radioactive iodine?

Doctors use a different form of it: radioactive iodine. A substance that’s radioactive gives off a form of energy so intense that it’s capable of harming the body. But doctors have harnessed that power. When someone gets a small dose of radioactive iodine, scanners can pick it up, and it can help reveal certain illnesses. Larger doses can attack thyroid cancer, prostate cancer, and other diseases.

What happens if you get a small dose of radioactive iodine?

When someone gets a small dose of radioactive iodine, scanners can pick it up , and it can help reveal certain illnesses. Larger doses can attack thyroid cancer, prostate cancer, and other diseases.

What are some examples of radioactive substances?

In science fiction movies, things that are radioactive almost always cause trouble. But in real life, doctors can use some of them to help people. Radioactive iodine is a good example. Ordinary iodine is one of the basic nutrients our bodies need, and we get it through food. The thyroid, a gland in the neck, uses it to make a hormone ...

How long does it take to get a radioactive disk out?

The operation to insert the disk lasts about 2 hours. Taking it out usually needs less than an hour. It may take 3 to 6 months for the radiation to have its full effect on the cancer. Cervical and Uterine Cancer. If you’re a woman with cervical or uterine cancer, radioactive iodine may be a treatment option.

How long does iodine stay in the uterus?

It will probably have to stay there for 2 or 3 days.

Does iodine kill thyroid cells?

Radioactive iodine can kill the cells that make up the thyroid gland and thyroid cancer. If thyroid cancer has spread to other parts of the body, radioactive iodine can attack the disease there, too. There’s another advantage to using it.

Can radioactive iodine show cancer?

Your doctor will use other tests to know for sure. Radioactive iodine can also show whether cancer has spread beyond the thyroid.

How to test thyroid for radioactive iodine?

Your doctor will observe your thyroid's activity level by measuring the amount of iodine it absorbs. He or she will do this using a scan of your thyroid, which will show the healthy and diseased tissues.

What is radioactive iodine ablation?

Your doctor may refer to it as radioactive iodine ablation (ablation is a term that refers to destruction or erosion). This article will focus on what you might expect when you are faced with the total elimination of your thyroid gland and its key functions. Graves disease, the most common form of hyperthyroidism, occurs most often in women, ...

How to determine the best dose of iodine?

In determining the best dose, the size of the thyroid gland (determined by a physical exam) and results of the uptake test are the two most important factors. The larger the gland, the larger the radioactive iodine dose. The higher the iodine uptake, the smaller the dose.

What are the side effects of iodine?

Other side effects of radioactive iodine include: 1 Metallic taste in the mouth: This can last for a few weeks. 2 Nausea: This usually subsides one to two days after treatment. 3 Swollen salivary glands: This can last for a few weeks. It is caused by iodine absorbed by the salivary glands, though stimulating saliva flow a day after treatment (by sucking a lemon drop, for instance) is an effective remedy.

How long after iodine treatment can you drink water?

For the first 3 days after treatment, stay a safe distance away from others (6 feet is enough). Avoid public places and drink plenty of water (to encourage the removal of radioactive iodine through your urine). For the first three days, do not share items (utensils, bedding, towels, and personal items) with anyone else.

How long does iodine last?

Other side effects of radioactive iodine include: Metallic taste in the mouth: This can last for a few weeks. Nausea: This usually subsides one to two days after treatment. Swollen salivary glands: This can last for a few weeks.

What cells absorb iodine?

Thyroid cells are the main cells in the body that can absorb iodine, so there is very little radiation exposure to the rest of your body's cells. When the thyroid cells absorb the radiation, they are damaged or destroyed. Approximately 90% of patients need only one dose before they are cured of their hyperthyroidism.

What is radioactive iodine used for?

Radioactive iodine is a procedure that is often used to treat hyperthyroidism.

Why do people get radioactive iodine?

Most people who get radioactive iodine treatment do so because they are considered to be hyperthyroid ( sometimes people get RAI for thyroid cancer (5) but most people get it for hyperthyroidism).

How long does iodine affect sperm count?

Important to men is the fact that radioactive iodine can cause short-term reductions in sperm count for up to 2 years after your procedure (8).

How long can you live after iodine treatment?

You can expect to live a fairly normal life after radioactive iodine treatment but your life will probably not be exactly as it was before your procedure. For most people, this means that you can expect to live at 80-90% of your 'normal'.

How long does it take for a RAI to fade?

The good news is that this radioactivity does fade over a short period of time (usually 5 to 7 days) but the bad news is that you need to stay under certain precautions during this time.

What happens if your thyroid is destroyed?

Once your thyroid is destroyed, it will no longer work exactly as it used to.

What happens if you destroy your thyroid gland?

And, if you destroy your thyroid gland, it turns out that that may have consequences on your metabolism. Anectodally, you've probably already heard stories about people gaining weight after their procedure.

What is radioactive iodine?

Radioactive iodine ablation therapy is a reliable procedure for treating hyperthyroidism patients. To understand what radioactive iodine treatment is and how it works, read on. In the human body, thyroid is the only organ that has ability to absorb iodine.

Why is iodine used in thyroid medicine?

In fact, iodine is crucial for normal production of the thyroid hormones. Taking these into consideration, radioactive iodine therapy is purported to deal with ailments related to the thyroid gland. In the United States, radioactive iodine ablation of the thyroid is the most commonly proceeded therapeutic method for hyperthyroidism.

How does iodine get out of the body?

After radioactive iodine ablation of the thyroid is over, the advocated iodine is expelled from body via urination. One should strictly follow the directions suggested by the concerned doctor for getting prompt results, and also, for minimizing the risks associated with radiation therapy.

How long does it take for hyperthyroidism to go away?

Most likely, the symptoms of hyperthyroidism will disappear gradually after about 2 weeks of the treatment session. Coming to the working of radioactive iodine therapy, the delivered RAI is quickly assimilated by the digestive parts (stomach and intestine).

Is radioactive iodine safe for thyroid cancer?

In addition to hyperthyroidism, radioactive iodine treatment for thyroid cancer is found to be equally effective. In general, a patient diagnosed with thyroid cancer receives two treatment options, radioactive ablation and surgical procedure. The former aids in killing cancerous cells right in the thyroid glands and remaining areas of the body.

Is radioactive iodine ablation effective?

Also, when compared to antithyroid drugs, radioactive ablation is found to be more effective in curing hyperthyroidism patients permanently.

Can radioactive iodine cause hypothyroidism?

In case of high intake of radioiodine, there are chances that the thyroid gland becomes underactive, resulting in hypothyroidism symptoms. For such a case, thyroid hormone pills are recommended. Overall, the effectiveness of radioactive iodine treatment is highly impressive, and its side effects occur in rare cases.

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