Treatment FAQ

how does osteoporosis treatment work

by Elian Fisher Published 3 years ago Updated 2 years ago
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Some of the more common osteoporosis medications and how they work include:

  • Bisphosphonates: interfere with the action of osteoclasts (cells that break down bones).
  • Selective Estrogen Receptor Modulators (SERMs): increase bone density by selectively acting as estrogen in bone.
  • Hormone Replacement Therapy (HRT): protects bone mass by replacing hormones that decrease after...

Most osteoporosis medications work by reducing the rate at which your bones break down. Some work by speeding up the bone-building process. Either mechanism strengthens bone and reduces your risk of fractures.

Full Answer

What is the best and safest treatment for osteoporosis?

Aug 13, 2020 · Because bone rebuilding cannot keep pace, bones deteriorate and become weaker. Most osteoporosis medications work by reducing the rate at which your bones break …

What happens when a person develops osteoporosis?

AACE/ACE, ACR, NAMS, and the Endocrine Society recommend bisphosphonates, excluding ibandronate, as a first-line option for the prevention and/or treatment of osteoporosis in …

What medications increase osteoporosis?

One effect is prevention of bone resorption. Doctors typically use raloxifene in addition to other osteoporosis medications, not by itself. Because raloxifene may also reduce the risk of breast ...

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What is the most effective treatment for osteoporosis?

Bisphosphonates. For both men and women at increased risk of fracture, the most widely prescribed osteoporosis medications are bisphosphonates. Examples include: Alendronate (Binosto, Fosamax)Aug 21, 2021

Can osteoporosis be reversed with medication?

The short answer is no, osteoporosis cannot be completely reversed and is not considered curable, but there are a number of health and lifestyle adjustments you can make to improve bone loss. Your provider may also prescribe you medications to help rebuild and slow down bone loss.Aug 9, 2021

How long does it take for osteoporosis medicine to work?

For osteoporosis, risedronate usually starts to work after 2 weeks. However, it may take 6 months for the medicine to fully protect your bones. When used for Paget's disease of bone, risedronate reduces bone pain, but it may take 3 to 6 months for your symptoms to improve.

How effective are osteoporosis drugs?

Depending on the body part (whether it's the spine or the hip or another bone in the body), taking an osteoporosis medication will reduce the chances of fracture anywhere from 50 to 70 percent — a substantial reduction in risk, says Khosla. “The side effects are quite rare.May 14, 2019

What is the fastest way to increase bone density?

Keep reading for tips on increasing bone density naturally.
  1. Weightlifting and strength training. ...
  2. Eating more vegetables. ...
  3. Consuming calcium throughout the day. ...
  4. Eating foods rich in vitamins D and K. ...
  5. Maintaining a healthy weight. ...
  6. Avoiding a low calorie diet. ...
  7. Eating more protein. ...
  8. Eating foods rich in omega-3 fatty acids.
Jul 30, 2019

Does walking increase bone density?

By simply taking regular brisk walks, you can improve your bone density and reduce your risk of hip fractures.Jan 17, 2018

What is the life expectancy of a person with osteoporosis?

This excess risk is more pronounced in the first few years on treatment. The average life expectancy of osteoporosis patients is in excess of 15 years in women younger than 75 years and in men younger than 60 years, highlighting the importance of developing tools for long-term management.

What are the stages of osteoporosis?

The stages of Osteoporosis
  • Osteoblasts vs Osteoclasts. Active Osteoblasts. ...
  • Peak bone density and the first stages of osteopenia and osteoporosis. ...
  • The second stage of osteopenia and osteoporosis. ...
  • The third stage of osteopenia and osteoporosis. ...
  • The fourth stage of osteopenia and osteoporosis.

What should you not do if you have osteoporosis?

If you have osteoporosis, don't do the following types of exercises: High-impact exercises. Activities such as jumping, running or jogging can lead to fractures in weakened bones. Avoid jerky, rapid movements in general.

What is the safest drug to take for osteoporosis?

Bisphosphonates are usually the first line of treatment for osteoporosis. That means your healthcare provider would probably prescribe Fosamax, Boniva, or another bisphosphonate before prescribing Prolia. Fosamax is only available in pill form, but Boniva is available as a pill or a shot.Jan 29, 2021

What is the infusion given for osteoporosis?

Zoledronic acid (ZOL) is an intravenous bisphosphonate that is given once yearly for the treatment of osteoporosis via a medically supervised 15-minute infusion.Oct 14, 2010

Is osteoporosis a terminal illness?

Osteoporosis itself is not fatal. However, a fracture in the bone, particularly the hip, can have fatal outcomes, especially in women with osteoporosis. Hip fractures, even for patients with no bone disease take long to heal, and the period of immobility involved in healing can be longer for someone with osteoporosis.May 14, 2021

Which Medications Are Commonly Used For Osteoporosis Treatment?

Bisphosphonates are the most common medications prescribed for osteoporosis treatment. These include: 1. Alendronate (Fosamax) 2. Risedronate (Acto...

How Do Most Osteoporosis Medications Work?

With the exception of teriparatide, osteoporosis medications slow bone breakdown. Healthy bones continuously break down and rebuild.As you age — es...

How Do You Know If You're Taking The Right bisphosphonate?

Drugs in the bisphosphonate class are more alike than they are different. They all help maintain bone density. And, all bisphosphonates have been s...

When Might Other Osteoporosis Medications Be used?

Drugs such as denosumab, teriparatide and abaloparatide can be used by anyone with osteoporosis, but are more likely to be recommended for people w...

What Are Common Side Effects of Bisphosphonate pills?

Bisphosphonate pills aren't absorbed well in the stomach. The main side effects of bisphosphonate pills are stomach upset and heartburn. Generic fo...

Do Intravenous Bisphosphonates Have Advantages Over The Pill form?

Infused forms of bisphosphonates don't cause stomach upset. And it may be easier for some women to schedule a quarterly or yearly infusion than to...

Can Bisphosphonates Hurt Your Bones?

Long-term bisphosphonate therapy has been linked to a rare problem in which the upper thighbone cracks and may break. This injury, known as atypica...

How Long Should You Take A Bisphosphonate For Osteoporosis Treatment?

There's some uncertainty about how long to take bisphosphonates because of a lack of long-term studies. Bisphosphonates have been shown to be safe...

What Happens If You Break A Bone While Taking An Osteoporosis medication?

Osteoporosis medications lower the chance of fracture, but they don't eliminate all risk of breaking a bone. If you have a fracture while on treatm...

Can Medication Alone Successfully Treat Osteoporosis?

Don't rely entirely on medication as the only treatment for your osteoporosis. These practices also are important: 1. Exercise. Weight-bearing phys...

What is the best treatment for osteoporosis?

If you can't tolerate the more common treatments for osteoporosis — or if they don't work well enough — your doctor might suggest trying: Teriparatide (Forteo). This powerful drug is similar to parathyroid hormone and stimulates new bone growth. It's given by daily injection under the skin.

What is the drug used for osteoporosis?

It's given by daily injection under the skin. After two years of treatment with teriparatide, another osteoporosis drug is taken to maintain the new bone growth. Abaloparatide (Tymlos) is another drug similar to parathyroid hormone.

Can testosterone be used for osteoporosis?

Testosterone replacement therapy can help improve symptoms of low testosterone, but osteoporosis medications have been better studied in men to treat osteoporosis and thus are recommended alone or in addition to testosterone.

How to reduce the risk of osteoporosis?

Smoking increases rates of bone loss and the chance of fracture. Avoid excessive alcohol. Consuming more than two alcoholic drinks a day might decrease bone formation.

What supplements can help with osteoporosis?

Alternative medicine. There is limited evidence that certain supplements, such as vitamin K-2 and soy, can help lower fracture risk in osteoporosis, but more studies are needed to prove benefits and determine risks.

How to measure bone density?

Your bone density can be measured by a machine that uses low levels of X-rays to determine the proportion of mineral in your bones. During this painless test, you lie on a padded table as a scanner passes over your body. In most cases, only a few bones are checked — usually in the hip and spine.

What are the side effects of bisphosphonates?

Examples include: Side effects include nausea, abdominal pain and heartburn-like symptoms. These are less likely to occur if the medicine is taken properly.

What is the best medication for osteoporosis?

Bisphosphonates are the most commonly used prescription medications for osteoporosis. There are three major drugs in this family: 1 Actonel 2 Boniva 3 Fosamax

Does calcitriol help with osteoporosis?

Since vitamin D is essential for bone health, calcitriol might be expected to help. In treating or preventing osteoporosis, calcitriol has shown promise in some studies, but not in others. Also, this drug requires periodic monitoring of calcium levels.

Is raloxifene good for osteoporosis?

Doctors typically use raloxifene in addition to other osteoporosis medications, not by itself. Because raloxifene may also reduce the risk of breast cancer, it may be a good medicine for someone with osteoporosis who is also at high risk for breast cancer.

Does calcitonin help with bone loss?

Taken as a medicine, calcitonin slows bone loss, increases bone density, and may relieve bone pain. It is most often used as additional therapy, or when someone cannot tolerate a bisphosphonate. The key health benefit: Reducing the risk of spinal fractures.

What is raloxifene used for?

Raloxifene is a selective estrogen receptor modulator, or SERM, originally used to treat breast cancer. Now, it’s also approved to prevent and treat osteoporosis. Raloxifene binds to estrogen receptors throughout the body to produce some estrogen-like effects. One effect is prevention of bone resorption.

Does teriparatide cause bone loss?

Teriparatide is a prepared form of human parathyroid hormone. This hormone has a tricky effect. Constant high levels of parathyroid hormone cause bone resorption and loss. But intermittent doses of teriparatide cause bone formation. Teriparatide is the only medicine today proven to stimulate bone growth.

Can postmenopausal women take vitamin D?

Many women have low vitamin D levels but don't know it, according to Rhee. Since vitamin D in normal doses is cheap and risk-free, a good option for most postmenopausal women is to take a combined vitamin D and calcium supplement every day.

What are some exercises to help with osteoporosis?

So is regular weight-bearing exercise, such as weight training, walking, hiking, jogging, climbing stairs, tennis, and dancing . If you have osteoporosis, avoid activities that involve twisting your spine or bending forward from the waist, such as conventional sit-ups, toe touches, or swinging a golf club.

How do you know if you have osteoporosis?

For some people, the first sign of osteoporosis is to realize they are getting shorter or to break a bone easily. Don’t wait until that happens to see if you have osteoporosis. You can have a bone density test to find out how strong your bones are.

Why is osteoporosis considered a silent disease?

Osteoporosis is called a “silent disease” because you may not notice any changes until a bone breaks. All the while, though, your bones had been losing strength for many years. Bone is living tissue. To keep bones strong, your body breaks down old bone and replaces it with new bone tissue.

Is osteoporosis common in older people?

Risk Factors and Causes. Although osteoporosis can strike at any age, it is most common among older people, especially older women. Men also have this disease. White and Asian women are most likely to have osteoporosis. Other women at great risk include those who: Have a family history of broken bones or osteoporosis.

Is osteoporosis a woman's disease?

Osteoporosis is not just a woman’s disease. Not as many men have it as women do, maybe because most men start with more bone density. As they age, men lose bone density more slowly than women. But, men need to be aware of osteoporosis. Experts don’t know as much about this disease in men as they do in women. However, many of the things that put men ...

What are the risk factors for osteoporosis?

Low levels of testosterone, too much alcohol, taking certain drugs, and smoking are other risk factors. Older men who break a bone easily or are at risk for osteoporosis should talk with their doctors about testing and treatment.

How to keep bones strong?

To keep bones strong, your body breaks down old bone and replaces it with new bone tissue. Sometime around age 30, bone mass stops increasing, and the goal for bone health is to keep as much bone as possible for as long as you can. As people enter their 40s and 50s, more bone may be broken down than is replaced.

Is osteoporosis a disease?

After all, medications are for diseases, and osteoporosis is not really a disease! It’s what your body does in response to an imbalance. Simply correcting that imbalance by natural means can correct the problem. Natural alternatives in the form of diet and supplements can stop and reverse bone loss.

Can osteoporosis medications cause muscle pain?

In fact, not only do they have some unpleasant side effects such as nausea, esophageal inflammation, and muscle pain, they may actually damage your bones themselves!

Can osteoporosis cause jawbone loss?

This is a condition that causes your jaw to develop deep infections that can result in the loss of your jawbone. Some informative studies have shown that bisphosphonates – one of the most common osteoporosis medications – actually….

How do bisphosphonates work?

Generally speaking, osteoporosis medications work by either stopping bone loss or by stopping bone loss and increasing bone density (“antiresorptives”). Some of the more common osteoporosis medications and how they work include:

What does it mean to treat osteoporosis?

Successfully treating osteoporosis also means making healthy changes to certain aspects of your lifestyle. Without these changes, you’re more likely to experience bone loss and have an increased risk for fractures. You can help boost your treatment’s effectiveness by:

What is the best medication for osteoporosis?

Bisphosphonates are the most commonly prescribed osteoporosis medications, and they must be taken properly to ensure they work correctly. These types of medications prevent bone loss while also helping to increase bone mass. However, you may have concerns about certain side effects bisphosphonates may cause.

Can bisphosphonates cause femoral fractures?

However, you may have concern s about certain side effects bisphosphonates may cause. The research shows that side effects like atypical femoral fractures may occur —but these complications usually develop in people with severe osteoporosis or those undergoing treatment for other diseases, like cancer.

How to help with bone loss?

Excess alcohol may interfere with your body’s ability to form new bone. Eating a well-balanced diet. A healthy diet rich in calcium and vitamin D helps keep your bones healthy and strong.

What happens if you don't take your medication?

Think about it: if you don’t take your medications like your doctor prescribed, there’s no way they can work to prevent further bone loss. If your initial osteoporosis treatment isn’t working, talk with your doctor about your specific treatment plan.

How to prevent fractures in bones?

Weight-bearing exercises strength en your bones and help prevent fractures. Preventing falls. Wearing low-heeled shoes and removing obstacles, such as electrical cords, inside your home can help keep you from falling and fracturing a bone. Quitting smoking. Smoking increases the rate of bone loss within your body.

What is an anabolic agent?

Anabolic agents: These once-a-day injectable medications , including teriparatide (Forteo) and abaloparatide (Tymlos), chemically resemble a portion of parathyroid hormone, which is produced naturally in your body. They increase bone mass by stimulating new bone formation.

What is the most common treatment for osteoporosis?

These complications are not so much related to the nature of the disease, but more with the drugs used in the treatment, primarily bisphosphonates as the most common remedy for osteoporosis.

Can osteoporosis be prevented?

Osteoporosis can be prevented and treated, and therefore , patients should regularly consult a doctor and follow the doctor’s instructions. To raise the level of global awareness about the prevention, diagnosis and treatment of osteoporosis and other metabolic bone diseases, since 1996, on the initiative of the International Osteoporosis Foundation, ...

Can a dentist detect osteoporosis?

The dentist, during a regular dental exam, can detect early changes in oral cavity that may indicate the presence of osteoporosis. Thanks to early detection of osteoporosis, it is possible to successfully treat and avoid many complications which the disease can cause.

What are the early signs of osteoporosis?

Early signs in the mouth that may indicate the presence of osteoporosis are: loose teeth, periodontal disease, dentures which are not well-fitting due to rapid degradation of the jaw bone and difficulties with eating and speaking.

What is the most common metabolic bone disease?

Osteoporosis is the most common metabolic bone disease where a gradual and initially imperceptible loss of bone mass occurs. In this disease, the activity of osteoclasts (cells that biodegrade bone) and osteoblasts (cells that build bone) is out of balance. Namely, the osteoclasts degrade significantly more bone than the osteoblasts are able ...

Why do dentists take X-rays of teeth?

In addition, periodically taking X-rays of the teeth and jaws for the needs of dental treatment allows the dentist to monitor changes in jaw bone density over a period of time. In the advanced stage this disease can lead to severe periodontal disease, tooth loss and accelerate the disappearance of alveolar bone of the jaw. ...

Which drugs increase bone density?

Many people with low bone density and/or osteoporosis receive drugs from the group of bisphosphonates (alendronate, ibandronate, risedronate, etidronate, raloxifene, etc.) that successfully increase bone density and prevent the occurrence of fractures.

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Diagnosis

Treatment

  • Treatment recommendations are often based on an estimate of your risk of breaking a bone in the next 10 years using information such as the bone density test. If your risk isn't high, treatment might not include medication and might focus instead on modifying risk factors for bone loss and falls.
See more on mayoclinic.org

Clinical Trials

  • Explore Mayo Clinic studiestesting new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition.
See more on mayoclinic.org

Lifestyle and Home Remedies

  • These suggestions might help reduce your risk of developing osteoporosis or breaking bones: 1. Don't smoke.Smoking increases rates of bone loss and the chance of fracture. 2. Limit alcohol.Consuming more than two alcoholic drinks a day may decrease bone formation. Being under the influence of alcohol also can increase your risk of falling. 3. Prevent falls.Wear low-he…
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Preparing For Your Appointment

  • Your doctor might suggest bone density testing. Screening for osteoporosis is recommended for all women over age 65. Some guidelines also recommend screening men by age 70, especially if they have health issues likely to cause osteoporosis. If you have a broken bone after a minor force injury, such as a simple fall, bone density testing may be important to assess your risk of more fr…
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