
Hormone therapy is a type of cancer treatment that removes, blocks, or adds specific hormones to stop or slow the growth of cancer cells. Like other cancer treatments, hormone therapy can cause side effects. Side effects can be different for each person. The side effects of this treatment can depend on many factors, including:
How do hormones affect cancer treatment?
Hormone therapy is a type of cancer treatment that removes, blocks, or adds specific hormones to stop or slow the growth of cancer cells. Like other cancer treatments, hormone therapy can cause side effects. Side effects can be different for each person. The side effects of this treatment can depend on many factors, including: Type of cancer
How long does hormone therapy last after cancer treatment?
Some cancers depend on hormones to grow. Because of this, treatments that block or alter hormones can sometimes help slow or stop the growth of these cancers. Treating cancer with hormones is called hormone therapy, hormonal therapy, or endocrine therapy.
What are the side effects of hormone therapy for prostate cancer?
Jul 07, 2021 · Hormone therapy (also called hormonal therapy, hormone treatment, or endocrine therapy) slows or stops the growth of hormone-sensitive tumors by blocking the body’s ability to produce hormones or by interfering with effects of hormones on breast cancer cells.
What should I read about hormone therapies for cancer?
And the more your cells divide and multiply, the more chance there is for something to go wrong and for cancer to develop. There are several things that can affect your hormones, including medications, chronic i nflammation and medical conditions like obesity. For other factors, like toxins and diet, the link to cancer risk is less clear.

Does chemo mess with your hormones?
Chemotherapy drugs can affect your hormones, your sex life, and your reproductive system. In women, it can increase your susceptibility to infections or trigger early menopause. Men may experience erectile dysfunction.Apr 21, 2021
How does cancer affect your hormones?
When cancer treatments change hormone levels, they usually lower the amount of particular hormones. They can do this by blocking the action of hormones, or by reducing the amount of the hormone the body makes. Sometimes, treatments can stop the body making a particular hormone altogether.
What are some negative side effects of cancer treatment?
Side Effects of Cancer TreatmentAnemia.Appetite Loss.Bleeding and Bruising (Thrombocytopenia)Constipation.Delirium.Diarrhea.Edema (Swelling)Fatigue.More items...
Does chemo increase estrogen?
Chemotherapy drugs: Some chemo drugs can damage the ovaries of pre-menopausal women so they no longer make estrogen. Ovarian function can return months or years later in some women, but in others the damage to the ovaries is permanent and leads to menopause.Oct 27, 2021
What cancers are affected by hormones?
Types of Hormone-Sensitive CancerBreast cancer. Some types need estrogen and progesterone to grow.Ovarian cancer. It can be affected by estrogen.Uterine or endometrial cancer. Estrogen and progesterone can fuel some types.Prostate cancer. Testosterone and similar hormones can help it grow and spread.Nov 2, 2021
Can a tumor cause hormone imbalance?
Because the pituitary gland plays an important role in hormone production, a tumor in the pituitary gland can lead to an imbalance of certain hormones in the body.
What is the most common side effect of cancer treatment?
Some of the most common side effects of cancer and its treatment include pain and fatigue, anemia, mouth problems, nausea/weight change/dietary issues, and hair, skin and nail problems. Pain. The term “pain” describes a broad category of types of symptoms and it is common to all cancers and cancer treatments.
What are the long term effects of cancer treatment?
What cancer treatments cause late effects?TreatmentLate effectsChemotherapyDental problems Early menopause Hearing loss Heart problems Increased risk of other cancers Infertility Loss of taste Lung disease Nerve damage Osteoporosis Reduced lung capacity5 more rows
What are the three most common side effects of chemotherapy?
Here are some of the more common side effects caused by chemotherapy:Fatigue.Hair loss.Easy bruising and bleeding.Infection.Anemia (low red blood cell counts)Nausea and vomiting.Appetite changes.Constipation.More items...•May 1, 2020
Does chemo affect menstrual cycle?
During chemotherapy, women may have irregular menstrual cycles or amenorrhea (disappearance of menstrual periods). Some medications used in chemotherapy may also cause damage to the ovaries, resulting in menopausal symptoms or menopause.
Is hormone therapy necessary after radiation?
Hormone therapy following surgery, radiation or chemotherapy has been shown to reduce the risk of breast cancer recurrence in people with early-stage hormone-sensitive breast cancers. It can also effectively reduce the risk of metastatic breast cancer growth and progression in people with hormone-sensitive tumors.Dec 29, 2020
Is hormone therapy better than chemotherapy?
Contrary to the commonly held view, 2 years after diagnosis, hormone therapy, a highly effective breast cancer treatment worsens quality of life to a greater extent and for a longer time, especially in menopausal patients. The deleterious effects of chemotherapy are more transient.Oct 9, 2019
What are hormones and hormone receptors?
Hormones are substances that function as chemical messengers in the body. They affect the actions of cells and tissues at various locations in the...
What is hormone therapy?
Hormone therapy (also called hormonal therapy, hormone treatment, or endocrine therapy) slows or stops the growth of hormone-sensitive tumors by bl...
What types of hormone therapy are used for breast cancer?
Several strategies are used to treat hormone-sensitive breast cancer: Blocking ovarian function: Because the ovaries are the main source of est...
How is hormone therapy used to treat breast cancer?
There are three main ways that hormone therapy is used to treat hormone-sensitive breast cancer: Adjuvant therapy for early-stage breast cancer: Ta...
Can hormone therapy be used to prevent breast cancer?
Yes. Most breast cancers are ER positive , and clinical trials have tested whether hormone therapy can be used to prevent breast cancer in women w...
What are the side effects of hormone therapy?
The side effects of hormone therapy depend largely on the specific drug or the type of treatment ( 7 ). The benefits and harms of taking hormone th...
Can other drugs interfere with hormone therapy?
Certain drugs, including several commonly prescribed antidepressants (those in the category called selective serotonin reuptake inhibitors , or...
Why is hormone therapy used?
Hormone therapy is mostly used to treat certain kinds of breast cancer and prostate cancer that depend on sex hormones to grow. A few other cancers can be treated with hormone therapy, too. Hormone therapy is considered a systemic treatment because the hormones they target circulate in the body. The drugs used in hormone therapy travel ...
What is the treatment for breast cancer?
Treating cancer with hormones is called hormone therapy, hormonal therapy, or endocrine therapy. Hormone therapy is mostly used to treat certain kinds of breast cancer ...
How does hormone therapy help cancer?
Alter the hormone so it doesn't work like it should. Hormone therapy can be used to: Treat a certain kind of cancer by stopping or slowing its growth. Lessen symptoms related to a certain type of cancer.
Where do you give hormone injections?
Some types of hormone therapy are injections given in the arm, leg, or hip. These are called intramuscular (or IM) injections. There are also types that are given just under the skin of the abdomen (belly). These are called subcutaneous (SC or sub-Q) injections. How often they are given depends on the drug and type of cancer being treated. The injections might be given in your treatment center or doctor's office. Sometimes patients are taught to give their own injections or a caregiver can be taught to give them.
Can you have oophorectomy for breast cancer?
Likewise, an oophorectomy (surgery to remove the ovaries, the body’s main source of estrogen and progesterone) can be an option for some women with breast cancer. Side effects from this type of hormone therapy tend to be like those from drugs that lower hormone levels in the body (see below).
What are the different types of estrogen receptor modulators?
Selective estrogen receptor modulators (SERMs), such as tamoxifen and raloxifene. Luteinizing hormone-releasing hormone (LHRH) agonists, such as goserelin, and leuprolide. Aromatase inhibitors (AIs), such as letrozole, anastrozole, and exemestane. See Hormone Therapy for Endometrial Cancer to learn more.
What type of surgery is used to remove the testicles?
Some types of surgery can also be forms of hormone therapy. For example, an orchiectomy (surgery to remove the testicles, the body’s main source of testosterone) can be an option for some men with prostate cancer who need hormone therapy as part of their treatment. Likewise, an oophorectomy (surgery to remove the ovaries, ...
What are the receptors in breast cancer?
Hormone-sensitive breast cancer cells contain proteins called hormone receptors ( estrogen receptors, or ERs, and progesterone receptors, or PRs) that become activated when hormones bind to them. The activated receptors cause changes in the expression of specific genes, which can stimulate cell growth.
How does hormone therapy work?
Hormone therapy (also called hormonal therapy, hormone treatment, or endocrine therapy) slows or stops the growth of hormone-sensitive tumors by blocking the body’s ability to produce hormones or by interfering with effects of hormones on breast cancer cells. Tumors that are hormone insensitive do not have hormone receptors ...
Which hormone is produced by the ovaries?
The hormones estrogen and progesterone are produced by the ovaries in premenopausal women and by some other tissues, including fat and skin, in both premenopausal and postmenopausal women and in men. Estrogen promotes the development and maintenance of female sex characteristics and the growth of long bones.
Can hormones be used for breast cancer?
Tumors that are hormone insensitive do not have hormone receptors and do not respond to hormone therapy. Hormone therapy for breast cancer should not be confused with menopausal hormone therapy (MHT)—treatment with estrogen alone or in combination with progesterone to help relieve symptoms of menopause. These two types of therapy produce opposite ...
What is the best treatment for ER positive breast cancer?
Hormone therapy is also a treatment option for ER-positive breast cancer that has come back in the breast, chest wall, or nearby lymph nodes after treatment (also called a locoregional recurrence). Two SERMs, tamoxifen and toremifene, are approved to treat metastatic breast cancer.
How to treat hormone sensitive breast cancer?
Several strategies are used to treat hormone-sensitive breast cancer: Blocking ovarian function: Because the ovaries are the main source of estrogen in premenopausal women, estrogen levels in these women can be reduced by eliminating or suppressing ovarian function. Blocking ovarian function is called ovarian ablation.
Does hormone therapy affect breast cancer?
These two types of therapy produce opposite effects: hormone therapy for breast cancer blocks the growth of HR-positive breast cancer, whereas MHT can stimulate the growth of HR-positive breast cancer. For this reason, when a woman taking MHT is diagnosed with HR-positive breast cancer she is usually asked to stop that therapy.
What are the things that affect hormones?
There are several things that can affect your hormones, including medications, chronic i nflammation and medical conditions like obesity.
How do hormones affect cancer?
Hormones and cancer: What's the link? Hormones can affect your weight, your body temperature and your cancer risk. BY Danielle Underferth. Hormones have a lot of power. They are the tiny chemicals that tell your body – right down to the cells – what to do. They determine everything from how big you will grow, to how you process food, ...
Does estrogen affect cancer?
They can also have an impact on your cancer risk, says Therese Bevers, M.D., medical director of MD Anderson’s Cancer Prevention Center. “When people hear the word hormone, they think of estrogen and progesterone, and their effects on female cancers,” Bevers says. “But there are several other hormones that have an impact on your risk ...
Do birth control pills cause cancer?
Birth control pills control fertility with doses of the female sex hormones estrogen and progesterone. They may lower the risk for ovarian and endometrial cancers. But they increase the risk for breast and cervical cancer slightly.
Can hormone replacement therapy cause breast cancer?
Hormone replacement therapy. For women past reproductive age, replacing declining hormones can alleviate some of the unpleasant symptoms of menopause. But hormone replacement therapy (HRT) can raise a woman’s risk for breast cancer and possibly ovarian cancer.
Does soy cause breast cancer?
But there’s not enough data to suggest that the plant estrogens in soy foods, like tofu and miso, increase the risk for breast or other cancers. In fact, soy may have a protective effect. “Soy is a plant estrogen. We really don’t know the benefits and harms as they relate to cancer risk,”Bevers says.
Does obesity cause inflammation?
Inflammation and obesity go hand-in-hand, and they both have an impact on hormones and cancer risk. Carrying too much body fat causes inflammation. Inflammation increases the amount of both insulin and estrogen in the body, which triggers cell division. Excess fat itself also produces estrogen.
How will I get hormone therapy?
The goal of hormone therapy, sometimes called endocrine therapy, is to starve the cancer of the hormones it needs to keep growing. Hormone therapy usually involves taking medications that either stop, block, or add hormones to slow the cancer cells’ growth. Hormone therapy may take place in many ways, which can include:
How do you determine if hormone therapy is right for me?
Your RMCC oncologist will determine whether hormone therapy may be a promising treatment option for you. He or she will do this by considering your specific cancer type, treatment goals, and personal preferences.
Will I have other treatments in addition to hormone therapy?
Your RMCC oncologist may recommend using hormone therapy in combination with other cancer treatments, such as chemotherapy and radiation therapy. When used with other treatments, hormone therapy can:
How often and for how long will I need hormone therapy?
How often you have hormone therapy will depend on the type of drug you are receiving and the type of cancer treated. Some medications need to be administered monthly, while others don’t have to be administered quite as frequently.
What is unique about receiving hormone therapy at Rocky Mountain Cancer Centers?
At Rocky Mountain Cancer Centers, your cancer care team will design a personalized cancer treatment plan that provides the ideal combination of therapies for the best possible outcome. Under our care, you will be monitored closely to determine if your hormone therapy is working.
What side effects can I expect after hormone therapy?
Because hormone therapy blocks your body’s ability to produce hormones or interferes with how hormones behave, it can cause unwanted side effects. The side effects you have will depend on the type of hormone therapy you receive and how your body responds.
Managing Hormonal Therapy Side Effects
Unfortunately, there is no way to determine how hormone therapy treatment will affect you. The good news is that many of these side effects are treatable, and most side effects go away once treatment is finished.
What hormones are used for endometrial cancer?
Cancer of the uterus or its lining, the endometrium, may respond to hormone therapy with progestins. Other types of hormone therapy for endometrial cancer include: 1 Tamoxifen 2 LHRH agonists 3 Aromatase inhibitors
What is the treatment for cancer called?
Also referred to as hormonal or endocrine therapy , this cancer treatment is different from menopausal hormone replacement therapy (HRT), which refers to the prescription of supplemental hormones to help relieve the symptoms of menopause. Certain cancers rely on hormones to grow.
How to get rid of cancer cells?
Hormone therapy may help make these hormones less available to growing cancer cells. Hormone therapy is available via pills, injection or surgery that removes hormone-producing organs, namely the ovaries in women and the testicles in men. It’s typically recommended along with other cancer treatments. If hormone therapy is part of your treatment ...
Does hormone therapy stop cancer?
Certain cancers rely on hormones to grow. In these cases, hormone therapy may slow or stop their spread by blocking the body’s ability to produce these particular hormones or changing how hormone receptors behave in the body. Breast and prostate cancers are the two types most commonly treated with hormone therapy.
What is the best treatment for endometrial cancer?
Hormonal therapy for endometrial cancer. Cancer of the uterus or its lining, the endometrium, may respond to hormone therapy with progestins. Other types of hormone therapy for endometrial cancer include: Tamoxifen. LHRH agonists.
Can aromatase inhibitors be used for premenopausal women?
Premenopausal women produce too much aromatase for the inhibitors to work effectively. (Aromatase inhibitor drugs may be prescribed for younger women if they’re given with a drug to suppress ovarian function.) Ask your care team whether you may benefit from aromatase inhibitors based on your cancer’s characteristics.
What is LHRH agonist?
LHRH agonists. Aromatase inhibitors. When and why they’re used: Hormone therapy is typically reserved for advanced uterine or endometrial cancer, or for cancer that has returned after treatment. It’s often combined with chemotherapy.
