Treatment FAQ

how can stem cells be used in modern treatment of disease

by Dr. Jacklyn Koepp Published 3 years ago Updated 2 years ago
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Stem cells could help medicine in three general ways: cell-based therapies, drug discovery and basic knowledge. Cell therapies would use stem cells, or cells grown from stem cells, to replace or rejuvenate damaged tissue. Scientists also want to use stem cells to understand disease and find drugs that might treat it.

In stem cell transplants, stem cells replace cells damaged by chemotherapy or disease or serve as a way for the donor's immune system to fight some types of cancer and blood-related diseases, such as leukemia, lymphoma, neuroblastoma and multiple myeloma. These transplants use adult stem cells or umbilical cord blood.

Full Answer

What diseases are cured by stem cells?

Stem cells are now used to treat lots of ailments and disorders like:

  • Diabetes
  • Heart Damage
  • Spinal Cord Injury
  • Arthritis
  • Cirrhosis
  • Ageing
  • Alzheimer’s
  • Cancer
  • Cerebral Palsy (CP)
  • Autism

What diseases can be cured and how with stem cells?

  • Diabetes
  • Heart disease
  • Spinal cord injuries
  • Parkinson’s disease
  • Alzheimer’s disease
  • Lou Gehrig’s disease
  • Lung diseases
  • Arthritis
  • Sickle cell anemia
  • Blood cancers, such as leukemia

More items...

What conditions and diseases can stem cell therapy treat?

  • Giving more highly selected stem cells from a donor around the time of a heart attack
  • Giving a patient’s own cardiac stem cells late after a heart attack
  • Giving highly selected, non-cardiac, stem cells from a donor later after a heart attack

What diseases can be treated with stem cell therapy?

  • Multiple Sclerosis. Multiple sclerosis is a chronic disease where inflammation is caused by the failure of the immune system, which damages cells of the brain or spinal cord.
  • Cardiovascular Diseases. ...
  • Diabetes and Diabetic Ulcer. ...
  • Autism. ...
  • Liver Diseases. ...
  • Crohn’s Disease. ...
  • Fibromyalgia. ...
  • Parkinson’s Disease. ...
  • Injuries and Musculoskeletal Pain. ...
  • COVID-19. ...

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Can stem cells be used to treat human diseases?

Stem cells may therefore be very useful as a therapy for diseases in which organs are damaged or where the immune system is too active. Some types of stem cells are already used for therapy, such as the hematopoietic (blood) stem cells, which are used for the treatment of bone marrow cancer.

How can stem cells be used in modern medical research?

Scientists can use stem cells, or tissues grown from them, to search for new drugs that improve their function or alter the progress of disease, as well as to test how drugs might affect different organs (for example, the liver or the kidneys), or how they might affect different people. For cell replacement.

Why should we use stem cells in medicine?

Stem cells could help medicine in three general ways: cell-based therapies, drug discovery and basic knowledge. Cell therapies would use stem cells, or cells grown from stem cells, to replace or rejuvenate damaged tissue. Scientists also want to use stem cells to understand disease and find drugs that might treat it.

How can stem cells be used?

Stem cell transplants are used to treat conditions in which the bone marrow is damaged and is no longer able to produce healthy blood cells. Transplants can also be carried out to replace blood cells that are damaged or destroyed as a result of intensive cancer treatment.

What are stem cells used for?

According to the National Institutes of Health (NIH), stem cells are being considered for a wide variety of medical procedures, ranging from cancer treatment to heart disease and cell-based therapies for tissue replacement. Advertisement.

How old are stem cells?

Embryonic, or pluripotent, stem cells are taken from human embryos that are less than a week old. These cells are wildly versatile, capable of dividing into more stem cells or becoming any type of cell in the human body (roughly 220 types, including muscle, nerve, blood, bone and skin). Researchers have also recently found stem cells in amniotic ...

What is the best treatment for cancer?

According to the International Society for Stem Cell Research, the "best defined and most extensively used (treatment) is blood stem cell transplantation to treat diseases and conditions of the blood and immune system, or to restore the blood system after treatments for specific cancers. Some bone, skin and corneal diseases or injuries can be ...

Can stem cells produce platelets?

Unlike other cells, these stem cells can produce oxygen-carrying red blood cells, infection-fighting white blood cells and clot-forming platelets [source: WebMD ]. These stem cells can be taken from the patient prior to radiation or chemotherapy treatment, or from a matching donor.

Is the FDA approving adult stem cells?

Currently the FDA has only approved the use of adult stem cells for bone marrow transplants, and is suing for the authority to regulate stem cell clinics. Perry, a staunch Republican, has consistently opposed the use of embryonic stem cells for medical research. However, he is a proponent of using adult stem cells.

Is adult stem cell more versatile than embryonic stem cell?

However, recent research has indicated that adult stem cells, once thought to be more limited in their capabilities, are actually much more versatile than originally believed. Though not as "pure" as embryonic stem cells, due to environmental conditions that exist in the real world -- ranging from air pollution to food impurities -- adult stem ...

Can stem cell therapy help with angina?

In July 2011, the American Heart Association released a study indicating that stem cell treatment might help patients with forms of angina that hadn't responded to other treatments, including angioplasty, prescription drugs or surgery [source: WebMD ].

What do we know about stem cells?

The most well-established and widely used stem cell treatment is the transplantation of blood stem cells to treat diseases and conditions of the blood and immune system, or to restore the blood system after treatments for specific cancers. Further, since the 1980s, skin stem cells have been used to grow skin grafts ...

What are skin stem cells used for?

Further, since the 1980s, skin stem cells have been used to grow skin grafts for patients with severe burns on very large areas of the body. A new stem-cell-based treatment to repair damage to the cornea (the surface of the eye) after an injury like a chemical burn has recently received marketing approval in Europe.

How do stem cells help the cornea?

Clinical studies in patients have shown that tissue stem cells taken from an area of the eye called the limbus can be used to repair damage to the cornea – the transparent layer at the front of the eye. If the cornea is severely damaged, for example by a chemical burn, limbal stem cells can be taken from the patient, multiplied in the lab and transplanted back onto the patient’s damaged eye (s) to restore sight. However, this can only help patients who have some undamaged limbal stem cells remaining in one of their eyes. The treatment has been shown to be safe and effective in clinical trials and has now been approved by regulatory authorities for widespread use in Europe. Limbal stem cells are one of only three stem cell therapies (treatments utilising blood stem cells and skin stem cells being the other two) that are available through healthcare providers in Europe.

Why are iPSCs important?

iPSCs, however, can help in these situations. iPSCs have huge implications for disease research and drug development.

How many people are treated with blood stem cells in Europe each year?

More than 26,000 patients are treated with blood stem cells in Europe each year. Since the 1980s, skin stem cells have been used to grow skin grafts for patients with severe burns on very large areas of the body.

Why is there high expectation on stem cell research but not yet high delivery of stem cell treatments?

Partly this is because complex diseases which are currently incurable require complex treatments ( often with a personalised aspect).

What are leukaemia studies?

Leukaemia studies. Cartilage or tendon injuries. It is worth noting that there are numerous other clinical trials (not listed here) aimed at. testing specific drugs to stimulate stem cells in the patient’s own body. deriving cells or cell lines to be used in research and clinical trials.

Why are stem cells important?

Stem cells have the potential to treat a wide range of diseases. Here, discover why these cells are such a powerful tool for treating disease—and what hurdles experts face before new therapies reach patients.

What is the most commonly used stem cell therapy?

Right now the most commonly used stem cell-based therapy is bone marrow transplantation. Blood-forming stem cells in the bone marrow were the first stem cells to be identified and were the first to be used in the clinic.

What is the biggest hurdle in stem cell therapy?

One of the biggest hurdles in any stem cell-based therapy is coaxing stem cells to become a single cell type. The vital process of maturing stem cells from one state to another type is called differentiation. Guiding stem cells to become a particular cell type has been fraught with difficulty.

What is stem cell transplant?

In a stem cell transplant, stem cells are first specialized into the necessary adult cell type. Then, those mature cells replace tissue that is damaged by disease or injury. This type of treatment could be used to: Replace neurons damaged by spinal cord injury, stroke, Alzheimer’s disease, Parkinson’s disease or other neurological problems; ...

What is stem cell tourism?

This phenomenon is called stem cell tourism and is currently a source of concern for reputable stem cell scientists. These predatory clinics are offering therapies that have not been tested to prove they are effective or even safe. In recent few years, some patients who visited those clinics have died, others have been left blind ...

Why is a cell line manufactured?

Under GMP standards, a cell line has to be manufactured so that each group of cells is grown in an identical, repeatable, sterile environment. This ensures that each batch of cells has the same properties, and each person getting a stem cell therapy gets an equivalent treatment. Updated 2/16. Share.

What could cells be used for?

The cells could be used to study disease, identify new drugs, or screen drugs for toxic side effects. Any of these would have a significant impact on human health without transplanting a single cell.

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