Treatment FAQ

hiv and diaboetes when to start treatment

by Maximillian Cassin Published 2 years ago Updated 2 years ago

In nearly all cases, people should start treatment with antiviral drugs as soon as they are diagnosed with HIV. In general, medical professionals now believe the best chance for an HIV (human immunodeficiency virus) patient to protect and maintain their immune system health is to start aggressive treatment upon diagnosis in almost all cases.

Full Answer

When is it time to start taking HIV medicines?

When is it time to start taking HIV medicines? Treatment with HIV medicines (called antiretroviral therapy or ART) is recommended for everyone with HIV. People with HIV should start taking HIV medicines as soon as possible after their HIV is diagnosed. A main goal of HIV treatment is to reduce a person’s viral load to an undetectable level.

Can diabetes be treated in HIV-positive patients?

As HIV-positive patients live longer, their risk for developing diabetes has increased along with their lifespans. Treating both of these conditions concurrently is challenging, but as with any other patient, lifestyle modification is a crucial component.

When should patients with HIV be screened for diabetes?

Patients with HIV should be screened for diabetes at diagnosis, at onset of HAART therapy, and three to six months after HAART.

What are the treatment recommendations for HIV infection?

The following recommendations apply to managing persons with diagnosed HIV infection: Link persons with HIV infection to care and start them on ART as soon as possible. Report cases (in accordance with local requirements) to public health and initiate partner services. Provide prevention counseling to persons with diagnosed HIV infection.

When should HIV treatment be started?

People with HIV should start taking HIV medicines as soon as possible after HIV is diagnosed. A main goal of HIV treatment is to reduce a person's viral load to an undetectable level. An undetectable viral load means that the level of HIV in the blood is too low to be detected by a viral load test.

What happens if you have diabetes and HIV?

People with HIV should have their blood glucose levels checked before they start taking HIV medicines. People with higher-than-normal glucose levels may need to avoid taking some HIV medicines. A healthy diet and regular physical activity can help prevent, delay, or manage type 2 diabetes.

How long can you live with HIV and diabetes?

Overall mean survival time was 19.7 years (95% CI, 19.57–19.8). For HIV alone (n=8266), the mortality rate was 3.6%; for HIV with diabetes (n=1720), mortality was almost three times higher (12.0%); and for HIV with diabetes and CKD (n=57), survival was less than three times higher (36.8%) than for HIV alone.

At what stage of HIV infection is antiretroviral treatment recommended?

HIV treatment involves taking highly effective medicines called antiretroviral therapy (ART) that work to control the virus. ART is recommended for everyone with HIV, and people with HIV should start ART as soon as possible after diagnosis, even on that same day.

Can a patient with preexisting diabetes start antiretroviral therapy?

In terms of diagnosis, treatment guidelines approved by the Infectious Diseases Society of America and ADA recommend that all HIV-positive patients be tested for diabetes before they begin taking antiretroviral therapy.

At what CD4 level should antiretroviral therapy start?

The authors conclude that a CD4 threshold of 350 cells/μL may be the optimal (or at least minimal) threshold for initiating antiretroviral therapy.

Why is it important to start taking HIV medicine?

To reduce their viral load, it’s important for people with HIV to start taking HIV medicines as soon as possible. Starting HIV medicines right away is especially important for people with HIV who have certain conditions.

What is the best treatment for HIV?

Treatment with HIV medicines (called antiretroviral therapy or ART) is recommended for everyone with HIV. HIV medicines help people with HIV live longer, healthier lives and reduce the risk of HIV transmission.

Why is it important to maintain an undetectable viral load?

People with HIV who maintain an undetectable viral load have effectively no risk of transmitting HIV to their HIV-negative partners through sex. To reduce their viral load, it’s important for people with HIV to start taking HIV medicines ...

What is AIDS defining condition?

AIDS-defining conditions are certain infections and cancers that are life-threatening in people with HIV. Having an AIDS-defining condition indicates that a person has the immune system of a person with acquired immunodeficiency syndrome (AIDS); starting HIV medicines as soon as possible can improve immune function.

What to talk to your health care provider about before taking HIV?

Before starting HIV treatment, it is important to talk to your health care provider about any issues that can make adherence difficult. For example, a busy schedule or lack of health insurance can make it hard to take HIV medicines consistently. Health care providers can recommend resources to help people deal with any issues that may interfere with adherence.

Why should pregnant women take HIV?

AIDS-defining conditions. Pregnancy. All pregnant women with HIV should take HIV medicines to protect their health and prevent mother-to-child transmission of HIV. All pregnant women with HIV should start taking HIV medicines as soon as possible during pregnancy. In most cases, women who are already on an effective HIV regimen when they become ...

Can HIV be treated early?

Studies suggest that even at this early stage of HIV infection, HIV medicines can begin to protect a person’s health. In addition, starting HIV medicines during early HIV infection reduces the risk of HIV transmission.

What to do if you have HIV and are worried about diabetes?

If you have HIV and are worried about diabetes, it’s a good idea to talk to your doctor about this risk and what you can do to protect your health.

Why are people with HIV and diabetes at higher risk?

Why There Is an Increased Risk. One reason more people have HIV and diabetes now is that better diagnosis and treatment of HIV means that people with this infection are living longer today. As people with HIV live longer, more of them are getting diabetes for the same reasons other people do. Some estimates show that on average, people treated ...

Why do people with HIV gain weight?

Some medicines used to treat HIV may cause people to gain weight. Because weight gain increases the risk for diabetes, this may put people with HIV at more risk. Many people with HIV have also have a hepatitis C infection. Hepatitis C has been linked to diabetes. People with HIV have inflammation as a result of the infection.

Can you live with HIV without diabetes?

Some estimates show that on average, people treated for HIV early can live nearly as long as people without HIV. But some things make diabetes more likely for people with HIV. High blood sugar is a side effect of some medicines that treat HIV. Doctors call high blood sugar hyperglycemia.

Is HIV more common than diabetes?

People living with HIV are more likely to get diabetes than people without it. One study showed that diabetes was up to four times more common in people with HIV .

Can HIV affect blood sugar?

Your doctor may want to check your blood sugar regularly to make sure it’s at a healthy level. If you have HIV and high blood sugar or diabetes, it may affect your treatment. People with high blood sugar may need to avoid certain HIV medicines.

Who wrote the op-ed "As a doctor, I’d rather have HIV than diabetes?

Last year, Max Pemberton, a psychiatrist in the United Kingdom’s National Health Service and a regular columnist for a number of publications, wrote an op-ed in The Spectator titled “As a doctor, I’d rather have HIV than diabetes.”. Pemberton makes the case that HIV has become a manageable chronic disease, and people with the disease have about ...

How many cases of HAART emergent diabetes per 1,000?

Dagogo-Jack notes that the estimated incidence of HAART-emergent diabetes ranges from 5.7 to 47.0 cases per 1,000 person-years and that the higher end came from older estimates with limited samples and the lower end estimates came from more recent larger databases so they may be closer to the truth. “With a working estimate of approximately 10 cases per 1,000 person-years, the majority of HIV patients receiving antiviral treatment would not develop diabetes,” he says.

How does HAART affect diabetes?

One of the first and most important steps for the patient should be lifestyle modification. Dagogo-Jack says that weight gain following initiation of HAART was a strong predictor of incident diabetes. He points to a 2015 article in HIV Medicine by Amit Acchra, PhD, of the University of New South Wales, Australia, that found an 11% increased risk of diabetes for each one-unit increase in BMI. “That’s a powerful opportunity for primary prevention with lifestyle intervention, as weight gain occurs frequently following successful treatment of HIV. There’s real opportunity for clinical researchers to translate well-known diabetes prevention initiatives in this particular population.”

What is the ultimate hope and end goal for both of these diseases?

Of course, the ultimate hope and end goal is for a cure for both of these diseases or a vaccine that prevents the transmission of HIV or the development of T2D, but that may be a long way off yet.

How many people have HIV?

HIV numbers are holding steady: According to the Centers for Disease Control and Prevention (CDC), there were 1.2 million people ages 13 and older in the U.S. with HIV at the end of 2012, and about 27,000 living with stage 3 of HIV (AIDS), but these people are living longer now that advances have been made in the past 30 years. Meanwhile, diabetes numbers continue to climb. The CDC estimates that there are now 29 million people with diabetes and 86 million with prediabetes, and most experts believe those numbers will continue to rise.

Is HIV worse than T2D?

He writes that HIV is “regarded in public health terms in the same category as, for example, type 2 diabetes,” but goes on to say that the prognosis for patients with T2D is much worse for those with HIV. The article raised some eyebrows, publicly and in the medical community, with some disagreeing with Pemberton because HIV ...

Can statins be used for HIV?

Some standard therapies, like statins, become less effective in HIV-positive patients, either through side-effect profiles that are not tolerable, or by interacting with and altering the metabolism of combined antiretroviral therapy (cART) medications. These can lead to ineffective cART or enhanced drug toxicities.

Is HIV a contributor to diabetes?

HIV and its treatment have been identified as potential contributors. Co-infections frequently observed during HIV infection also significantly influence both the epidemiological and pathophysiological of the link between HIV and diabetes.

Is HIV associated with insulin resistance?

HIV infection is associated with increased risk of insulin resistance, and ART is associated with metabolic derangement and the occurrence of type 2 diabetes. The increasing survival among people with HIV infection in developing countries is paralleled by a growing burden of chronic non-communicable ….

When should HIV testing be performed?

Testing for HIV should be performed at the time of STI diagnosis and treatment if not performed at the initial STI evaluation and screening ( 82, 195, 416 ).

When should a woman be tested for HIV?

All pregnant women should be tested for HIV during the first prenatal visit. A second test during the third trimester, preferably at <36 weeks’ gestation, should be considered and is recommended for women who are at high risk for acquiring HIV, women who receive health care in jurisdictions with high rates of HIV infection, and women served in clinical settings in which prenatal screening identifies ≥1 pregnant woman with HIV per 1,000 women screened ( 138 ). Diagnostic algorithms for HIV for pregnant women do not differ from those for nonpregnant women (see STI Detection Among Special Populations). Pregnant women should be informed that HIV testing will be performed as part of the routine panel of prenatal tests ( 138 ); for women who decline HIV testing, providers should address concerns that pose obstacles, discuss the benefits of testing (e.g., early HIV detection, treatment, and care for improving health of the mother and reducing perinatal transmission of HIV), and encourage testing at subsequent prenatal visits. Women who decline testing because they have had a previous negative HIV test result should be informed about the importance of retesting during each pregnancy. Women with no prenatal care should be tested for HIV at the time of delivery.

How long does it take to get a POC test?

Rapid POC HIV tests can enable clinicians to make a preliminary diagnosis of HIV infection in <20 minutes. The majority of rapid antibody assays become reactive later in the course of HIV infection than conventional laboratory-based assays and thus can produce negative results among persons recently infected (e.g., acutely infected persons). Furthermore, HIV home-test kits only detect HIV antibodies and therefore will not detect acute HIV infection. If early or acute infection is suspected and a rapid HIV antibody assay is negative, confirmatory testing with combined laboratory-based assays or RNA testing should be performed. CDC recommends that all persons with reactive rapid tests be assessed with a laboratory-based Ag/Ab assay. Additional details about interpretation of results by using the HIV testing algorithm recommended by CDC are available at https://stacks.cdc.gov/view/cdc/48472.

How to diagnose HIV?

HIV infection can be diagnosed by HIV 1/2 Ag/Ab combination immunoassays. All FDA-cleared HIV tests are highly sensitive and specific. Available serologic tests can detect all known subtypes of HIV-1. The majority also detect HIV-2 and uncommon variants of HIV-1 (e.g., group O and group N).

What test is used to test for HIV?

According to an algorithm for HIV diagnosis, CDC recommends that HIV testing begin with a laboratory-based HIV-1/HIV-2 Ag/Ab combination assay, which, if repeatedly reactive, is followed by a laboratory-based assay with a supplemental HIV-1/HIV-2 antibody differentiation assay ( https://stacks.cdc.gov/view/cdc/50872 ). This algorithm confers an additional advantage because it can detect HIV-2 antibodies after the initial immunoassay. Although HIV-2 is uncommon in the United States, accurate identification is vital because monitoring and therapy for HIV-2 differs from that for HIV-1 ( 420 ). RNA testing should be performed on all specimens with reactive immunoassay but negative supplemental antibody test results to determine whether the discordance represents acute HIV infection.

What are the challenges of HIV?

They face multiple adaptive challenges, including coping with the reactions of others to a stigmatizing illness, developing and adopting strategies to maintain physical and emotional health, initiating changes in behavior to prevent HIV transmission to others, and reducing the risk for acquiring additional STIs. Many persons will require assistance gaining access to health care and other support services and coping with changes in personal relationships.

What is the first test for HIV?

Providers should use a laboratory-based antigen/antibody (Ag/Ab) combination assay as the first test for HIV, unless persons are unlikely to follow up with a provider to receive their HIV test results; in those cases screening with a rapid POC test can be useful.

How to treat HIV?

Start HIV Treatment As Soon As Possible After Diagnosis. Get in care and take medicine to treat HIV (called antiretroviral therapy or ART). Taking HIV medicine can reduce the amount of HIV in the blood (called viral load ). HIV medicine can make the viral load very low (called viral suppression ).

How long does it take to get HIV under control?

Most people can get the virus under control within six months. Learn more about the benefits of HIV treatment. If playback doesn't begin shortly, try restarting your device.

How does HIV affect you?

Receiving an HIV diagnosis can be life changing. You may feel many emotions—sadness, hopelessness, or anger. Allied health care providers and social service providers can help you work through the early stages of your diagnosis. They are often available at your health care provider’s office.

What does it mean when you are diagnosed with HIV?

Newly Diagnosed with HIV. Español (Spanish) minus. Related Pages. What does an HIV diagnosis mean? If you receive an HIV diagnosis, it means that you have HIV. Unlike some other viruses, the human body can’t get rid of HIV completely. Once you have HIV, you have it for life. But with proper medical care, HIV can be controlled.

Who manages HIV?

If you have a primary health care provider , that person may have the knowledge to treat your HIV. A primary health care provider is someone who manages your regular medical care and annual tests.

Can you live with HIV?

Once you have HIV, you have it for life. But with proper medical care, HIV can be controlled. People with HIV who get effective HIV treatment can live long, healthy lives and protect their partners.

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