Treatment FAQ

epclusa how long treatment

by Deron Ward Published 3 years ago Updated 2 years ago
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Epclusa is a two-drug combination administered as a single daily pill containing the viral NS5A inhibitor Velpatasvir and Sofosbuvir. The treatment duration is 12 weeks for all genotypes. No ribavirin for most patients.

How many weeks do you take Epclusa?

It comes as a tablet you take by mouth once daily for 12 weeks. Epclusa was approved in 2016 and was the first medication to treat all six hepatitis C genotypes. It can be used for people with or without cirrhosis (scarring of the liver).

How long did it take for a hep C cure?

Better known as Sovaldi, the drug managed to recast hepatitis C from a hard-to-treat illness into an easily managed one that can be cured in just a few months. When used alongside other drugs it also worked much faster than any other hepatitis C treatments and had both fewer side effects and much higher success rates.

What is the 8 week treatment for hep C?

The FDA expanded approval of a hepatitis C drug that shortens treatment time to eight weeks. AbbVie's Mavyret tablets treat compensated cirrhosis in patients with chronic hepatitis C who weigh at least 99 pounds. Before approval of this drug, the standard treatment time was at least 12 weeks.

What does Epclusa do to your body?

Epclusa contains two antiviral ingredients, sofosbuvir and velpatasvir, and may be used to treat hepatitis C. Sofosbuvir interferes with the reproduction of genetic material of the hepatitis C virus, by inhibiting an RNA-dependent polymerase called HCV NS5B, which is also needed by the virus to replicate itself.

Can hep C be 100% cured?

Hepatitis C can be cured, and today's drug therapies are very effective and easier for patients to take, says Jeffrey S. Murray, M.D., an internist at the FDA who specializes in infectious diseases.

What happens after hep C is cured?

After you clear your hep C (being cured) you won't have any immunity to protect you from catching it again. You can lower your risk of catching hep C again by avoiding blood-to-blood contact with other people.

Do you still test positive for hep C after treatment?

Other things to know: After a successful course of treatment for hepatitis C, the hepatitis C antibody remains detectable, but the hepatitis C RNA will be undetectable. If you plan to donate blood, you will be tested for the hepatitis C antibody and will be turned away even if you do not have an active infection.

What is the success rate of hep C treatment?

Hepatitis C treatment can cure more than 90 percent of hepatitis C cases, but testing is a critical first step. It's estimated 40 percent of people with hepatitis C in the U.S. from 2015-2018 were unaware of their infection.

How long can a person live with hep C and cirrhosis?

People with cirrhosis can live for decades, especially if it's diagnosed early and managed well. About 5 to 20 percent of people with chronic hepatitis C will develop cirrhosis. With that in mind, it takes about 20 to 30 years for cirrhosis to develop in that population.

How do you know if Epclusa is working?

After you've finished the 12-week Epclusa treatment, you won't be cured of hepatitis C right away. You'll be considered “cured” when the hepatitis C virus is no longer detected in your blood. Three months after your treatment is completed, you will have a blood test to see if your treatment was successful.

What is the success rate of Epclusa?

Effectiveness: The cure rates are from 97% to 100% in those without cirrhosis or with compensated cirrhosis. Side effects: Most people don't experience significant side effects – but if they do the most common adverse reactions observed with treatment with Epclusa for 12 weeks are headache and fatigue.

Does Epclusa affect your teeth?

Side effects of Epclusa It rots your teeth! They mention that you may get dry mouth or a metallic taste but the never share the fact that this drug will rot your teeth.

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