Treatment FAQ

does more testing need to take place to determin what treatment to undergo for lymphoma

by Aleen Gleichner Published 2 years ago Updated 2 years ago

Common tests & procedures

Tests After Diagnosis. Once the diagnosis of lymphoma is clear, it becomes necessary to perform a number of tests to see how far the disease has spread and which organs are involved. Scans of different parts of the body as well as a bone marrow test may be done if the doctor feels it is required.

What tests are done after lymphoma diagnosis?

The likely clinical course can determine the approach or goal of therapy. For example, for aggressive lymphomas the most appropriate goal of therapy is usually to cure. For lymphomas with a variable clinical course a period of observation might be needed to judge its behavior.

What determines the approach or goal of therapy for lymphoma?

Diagnosing lymphoma can be challenging because many of the symptoms overlap with other common illnesses. Even when you’re told you have lymphoma, it’s often a challenge to identify the type.

Why is it difficult to diagnose lymphoma?

If a doctor initially asks for a needle aspiration cytology (called FNAC) and it turns out to be lymphoma, it is worthwhile to do a biopsy to get more tissue for a more detailed diagnosis. 2 The diagnosis of lymphoma is not enough information for a healthcare provider to give proper treatment.

When is a biopsy necessary for lymphoma diagnosis?

What tests are done to see if you have lymphoma?

Tests and procedures used to diagnose lymphoma include:Physical exam. Your doctor checks for swollen lymph nodes, including in your neck, underarm and groin, as well as a swollen spleen or liver.Removing a lymph node for testing. ... Blood tests. ... Removing a sample of bone marrow for testing. ... Imaging tests.

What is a lymphoma workup?

Typically, the “lymphoma workup” begins with basic laboratory evaluation of peripheral blood. Laboratory Evaluation of Peripheral Blood. The complete blood count provides not only cell counts, but also calculated values to include differentials and indices.

How fast does lymphoma spread?

After five to 10 years, low-grade disorders begin to progress rapidly to become aggressive or high-grade and produce more severe symptoms. This type progresses fairly rapidly without treatment. With treatment, remission can be induced in between 50 to 75 percent of cases.

Do cancerous lymph nodes show up on CT scan?

CT scans are different than standard x-rays because they create a series of pictures taken from different angles and produce much clearer images. A CT scan of the chest or abdomen can help detect an enlarged lymph node or cancers in the liver, pancreas, lungs, bones and spleen.

How to test for lymphoma?

Biopsy Is the First Step. To test for lymphoma, a doctor will perform an excisional biopsy, taking a small sample of tissue from the affected nodes or organs . The biopsy sample will be viewed under a microscope by a pathologist.

What tests are done after lymphoma diagnosis?

Scans of different parts of the body, as well as a bone marrow test , may be done if the doctor feels it is required. Also, some blood tests can show how advanced the ...

Can lymphoma cause weight loss?

Most people with lymphoma first notice enlarged lymph nodes in their neck, armpits or groin. They also may have a fever, weight loss, and other vague symptoms that can mimic other diseases. 1  Your doctor may suspect lymphoma based on the symptoms you have or from scans of affected parts of your body.

What is the treatment for non-Hodgkin lymphoma?

Many people treated for non-Hodgkin lymphoma will receive some form of chemotherapy, radiation therapy, biologic therapy, immunotherapy, or a combination of these. Bone marrow, stem cell transplantation, or CAR T-cell therapy may sometimes be used.

How long does non-Hodgkin lymphoma last?

Although “indolent” or slow growing forms of non-Hodgkin lymphoma are not currently curable, the prognosis is still very good. Patients may live for 20 years or more following an initial diagnosis. In certain patients with an indolent form of the disease, treatment may not be necessary until there are signs of progression.

Is lymphoma a heterogeneous disease?

Blood cancers, including lymphoma, are extremely heterogeneous, and can involve a variety of treatment options, often in combination. Some form of chemotherapy, radiation therapy, immunotherapy, or a combination is typically used to treat Hodgkin lymphoma. Bone marrow or stem cell transplantation may also sometimes be done under special ...

Why do people with non-Hodgkin lymphoma go to the doctor?

Most people with non-Hodgkin lymphoma (NHL) see their doctor because they have felt a lump that hasn’t gone away, they develop some of the other symptoms of NHL, or they just don’t feel well and go in for a check-up.

What is a CT scan for lymphoma?

A CT scan combines many x-rays to make detailed, cross-sectional images of your body . This scan can help tell if any lymph nodes or organs in your body are enlarged. CT scans are useful for looking for lymphoma in the abdomen, pelvis, chest, head, and neck.

What type of biopsy is used for lymphoma?

There are several types of biopsies. Doctors choose which one to use based on each person’s situation. Excisional or incisional biopsy: This is the preferred and most common type of biopsy if lymphoma is suspected, because it almost always provides enough of a sample to diagnose the exact type of NHL.

Why do doctors prescribe antibiotics for lymph nodes?

Because of this, doctors often prescribe antibiotics and wait a few weeks to see if the lymph nodes shrink . If the nodes stay the same or continue to grow, the doctor might order a biopsy. A biopsy might be needed right away if the size, texture, ...

Why is my lymph node swollen?

These tests can help determine whether a lymph node is swollen because of lymphoma, some other cancer, or a non-cancerous disease. The tests can also be used for immunophenotyping – determining which type of lymphoma a person has, based on certain proteins in or on the cells.

Why do doctors check for lymph nodes?

Because infections are the most common cause of enlarged lymph nodes, the doctor will look for an infection near the swollen lymph nodes. The doctor also might order blood tests to look for signs of infection or other problems. Blood tests aren't used to diagnose lymphoma, though.

Can a needle biopsy diagnose lymphoma?

Needle biopsy: Needle biopsies are less invasive than excisional or incisional biopsies, but the drawback is that they might not remove enough of a sample to diagnose lymphoma (or to determine which type it is). Most doctors do not use needle biopsies to diagnose lymphoma.

Why do people with Hodgkin lymphoma need a check up?

Tests for Hodgkin Lymphoma. Most people with Hodgkin lymphoma (HL) see their doctor because they have certain symptoms, or because they just don’t feel well and go in for a check-up. If a person has signs or symptoms that suggest HL, exams and tests will be done to find out for sure and, if so, to determine the exact type.

Why do doctors check for enlarged lymph nodes?

Because infections are the most common cause of enlarged lymph nodes, especially in children, the doctor will look for infection in the part of the body near any swollen lymph nodes. The doctor also might order blood tests to look for signs of infection or other problems.

What type of biopsy is done for enlarged lymph nodes?

There are different types of biopsies. Doctors choose the best one to do based on the situation. Excisional or incisional biopsy: This is the preferred and most common type of biopsy for an enlarged lymph node. The doctor cuts through the skin to remove the lymph node.

What is the purpose of Hodgkin lymphoma imaging?

To look for possible causes of certain symptoms, such as enlarged lymph nodes in the chest. To help determine the stage (extent) of Hodgkin lymphoma. To help show if treatment is working. To look for possible signs of cancer coming back after treatment. These are the imaging tests most commonly used:

What is the name of the doctor who looks at a biopsy of a tumor?

All biopsy samples are looked at under a microscope by a pathologist (a doctor specially trained to recognize cancer cells), who will look for Hodgkin lymphoma cells (called Reed-Sternberg cells). Sometimes the first biopsy doesn't give a clear answer and more biopsies are needed. Looking at the tissue samples under the microscope is often enough ...

What to do if lymph nodes shrink?

You may be given antibiotics to see if they cause the nodes to shrink. If the nodes don’t shrink or if they continue to grow, a lymph node (or a small piece of a node) is taken out to be checked in the lab. This procedure, called a biopsy, is the only way to be sure of the diagnosis.

How long does it take for lymph nodes to shrink?

Biopsies. Because swollen lymph nodes are more likely to be caused by something other than HL, like an infection, doctors often wait a few weeks to see if they shrink on their own as the infection goes away. You may be given antibiotics to see if they cause the nodes to shrink.

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Medically reviewed by
Dr. Rakshith Bharadwaj
Your provider may recommend one or more of these diagnostic tests and procedures as part of an evaluation.
Diagnosis involves physical examination and certain laboratory tests and imaging test to confirm the diagnosis of lymphoma when it is suspected.
Common tests & procedures

Physical examination: Examining the body for enlarged lymph nodes.

Complete blood count (CBC): To evaluate the number of blood cells and their nature.

CT scan: Provides detailed view of lymphatic system to identify any swollen lymph nodes.

Lymph node biopsy: Removing a part or an entire lymph node for microscopic examination to determine lymphoma and types of cells involved.

Bone marrow biopsy: Removing a small sample of bone marrow from the hipbone to check for lymphoma.

Magnetic resonance imaging (MRI): MRI - lymphangiography - provides detail view of lymphatic vessels.

Positron emission tomography (PET): To check for signs of lymphoma in different parts of the body.

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Preparing For Your Appointment

  • Which lymphoma treatments are right for you depends on the type and stage of your disease, your overall health, and your preferences. The goal of treatment is to destroy as many cancer cells as possible and bring the disease into remission. Lymphoma treatments include: 1. Active surveilla…
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