Treatment FAQ

clonidine is approved for the treatment of which conditions?

by Cordelia Spinka Published 2 years ago Updated 2 years ago
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Clonidine is prescribed for a range of conditions, including: Hypertension — otherwise known as high blood pressure; Clonidine’s primary use is as a treatment for hypertensive patients. ADHD – clonidine is FDA-approved for use in treating Attention Deficit Hyperactivity Disorder in both children and adults.

Clonidine is approved for the treatment of high blood pressure
high blood pressure
Uncontrolled hypertension requires medical attention and treatment. Keeping well hydrated by drinking 6-8 glasses of water daily (even more if working in hot and humid conditions) is beneficial for the blood pressure.
. It may be used alone or combined with other drugs used for the treatment of high blood pressure. Clonidine is also used off-label for the treatment of alcohol withdrawal, smoking cessation, restless leg syndrome, Tourette's syndrome, and opioid withdrawal.

Full Answer

What is the pharmacology of clonidine?

Aug 06, 2021 · Clonidine is an antihypertensive drug that lowers blood pressure and heart rate by relaxing the arteries and increasing the blood supply to the heart; it has other FDA-approved indications such as treatment of attention deficit hyperactivity disorder (ADHD) in children (FDA approval 2010); management of tics commonly found with Tourette syndrome; and adjunct …

Can I take clonidine twice a week?

Feb 21, 2018 · Aside from antihypertensive effects, clonidine can exert sedative, analgesic, and anxiolytic effects. 5 Therefore, beyond its approved indications, clonidine has been used more recently to treat a variety of psychiatric conditions which include attention deficit hyperactive disorder (ADHD), post-traumatic stress disorder (PTSD), and Tourette syndrome. 2, 6, 7 There …

How many clinical trials have been done on clonidine?

Clonidine is approved for the treatment of which conditions Select all that. Clonidine is approved for the treatment of which. School Chamberlain College of Nursing; Course Title NR NR509; Uploaded By steve2022; Pages 2 This preview shows page 1 - 2 out of 2 pages.

Is it safe to give Clonidine hydrochloride to a nursing mother?

Mar 09, 2007 · Clonidine hydrochloride tablets, USP are indicated in the treatment of hypertension. Clonidine hydrochloride tablets, USP may be employed alone or concomitantly with other antihypertensive agents. Contraindications. Clonidine hydrochloride tablets, USP should not be used in patients with known hypersensitivity to Clonidine (see PRECAUTIONS). Warnings

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What conditions does clonidine treat?

Clonidine is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly.Apr 1, 2022

Is clonidine FDA approved for ADHD?

The product is the first formulation of clonidine to be approved by the FDA for ADHD and also represents the first and only adjunctive treatment to stimulant therapy for the condition.Oct 7, 2010

Is clonidine approved for anxiety?

Clonidine may be particularly helpful for patients with impulsive behaviour or hyperactivity problems, and who may also have sleep difficulties, aggression, hostility, tics or anxiety disorders. Clonidine can be added to stimulants to treat any of these conditions.

When is clonidine used for hypertension?

An initial oral dose of 0.1 to 0.2 mg of clonidine hydrochloride followed by hourly doses of 0.05 or 0.1 mg until goal blood pressure is attained that does not reduce perfusion to critical organs, or a total of 0.7 mg is given, will achieve a significant reduction in blood pressure in 93% of patients.

When was clonidine approved?

Approval Date: 12/3/2009.May 12, 2010

Why is clonidine prescribed for ADHD?

Reduces blood pressure: If you have ADHD and high blood pressure, clonidine may be a good choice for you because it will also help reduce your blood pressure. Can treat tic disorders: If you have both Tourette syndrome or another tic disorder and ADHD, clonidine can help the symptoms of both.Oct 9, 2021

What is clonidine classified?

Clonidine is in a class of medications called centrally acting alpha-agonist hypotensive agents. Clonidine treats high blood pressure by decreasing your heart rate and relaxing the blood vessels so that blood can flow more easily through the body.May 15, 2017

Can clonidine be used as a mood stabilizer?

Clonidine has been reported to be effective in a variety of hyperadrenergic states, including mania. It is generally well-tolerated and does not result in the severe adverse effects that are associated with many antipsychotics and mood stabilizers used in the treatment of mania, such as weight gain and akathisia.

Is clonidine used for schizophrenia?

Clonidine Normalizes Sensorimotor Gating Deficits in Patients With Schizophrenia on Stable Medication.Jul 2, 2012

Does clonidine raise BP?

Clonidine raises blood pressure in severe idiopathic orthostatic hypotension.

Is clonidine a good blood pressure medicine?

Clonidine has an average rating of 6.0 out of 10 from a total of 85 ratings for the treatment of High Blood Pressure. 41% of reviewers reported a positive effect, while 33% reported a negative effect.

How much does clonidine lower BP?

Clonidine produced a consis- tent decrease in mean arterial pressure with an average reduction of 17% (P < 0.01).

Clonidine - Clinical Pharmacology

Clonidine stimulates alpha-adrenoreceptors in the brain stem. This action results in reduced sympathetic outflow from the central nervous system an...

Indications and Usage For Clonidine

Clonidine hydrochloride is indicated in the treatment of hypertension. Clonidine hydrochloride may be employed alone or concomitantly with other an...

Clonidine Dosage and Administration

AdultsThe dose of Clonidine hydrochloride USP must be adjusted according to the patient's individual blood pressure response. The following is a ge...

How Is Clonidine Supplied

Clonidine Hydrochloride Tablets, USP, are supplied as scored oval tablets containing 0.1 mg, 0.2 mg or 0.3 mg of Clonidine hydrochloride.0.1 mg tab...

Package LABEL.PRINCIPAL Display Panel - 0.1 Mg

Clonidine Hydrochloride Tablets, USP 0.1 mg (30 Tablets in 1 HDPE Bottle)Each tablet contains: Clonidine Hydrochloride USP 0.1 mg 46708-306-30

Package LABEL.PRINCIPAL Display Panel - 0.2 Mg

Clonidine Hydrochloride Tablets, USP 0.2 mg (30 Tablets in 1 HDPE Bottle)Each tablet contains: Clonidine Hydrochloride USP 0.2 mg46708-307-30

Package LABEL.PRINCIPAL Display Panel - 0.3 Mg

Clonidine Hydrochloride Tablets, USP 0.3 mg (30 Tablets in 1 HDPE Bottle)Each tablet contains: Clonidine Hydrochloride USP 0.3 mg 46708-308-30Medic...

What is clonidine used for?

Clonidine is also used in the treatment of dysmenorrhea (severely painful cramps during menstrual period), hypertensive crisis (a condition in which your blood pressure is very high), Tourette's syndrome (a condition characterized by the need to perform repeated motions or to repeat sounds or words),menopausal hot flashes, and alcohol and opiate (narcotic) withdrawal. Clonidine is also used and as an aid in smoking cessation therapy and to diagnose pheochromocytoma (a tumor that develops on a gland near the kidneys and may cause high blood pressure and fast heart rate). Talk to your doctor about the possible risks of using this medication for your condition.

Can you take Clonidine more than once a week?

Do not take more or less of it or take it more often than prescribed by your doctor. Swallow the extended-release tablets whole; do not split, chew or crush them. Your doctor may start you on a low dose of clonidine and gradually increase your dose, not more than once every week.

Can you stop taking Clonidine?

Continue to take clonidine even if you feel well. Do not stop taking clonidine without talking to your doctor. If you suddenly stop taking clonidine, it can cause a rapid rise in your blood pressure and symptoms such as nervousness, headache, and uncontrollable shaking of a part of the body.

Does clonidine cause high blood pressure?

Clonidine is also used and as an aid in smoking cessation therapy and to diagnose pheochromocytoma (a tumor that develops on a gland near the kidneys and may cause high blood pressure and fast heart rate). Talk to your doctor about the possible risks of using this medication for your condition.

What to do if you are allergic to Clonidine?

tell your doctor and pharmacist if you are allergic to clonidine, any of its ingredients, clonidine patches, or any other medications. Ask your pharmacist for a list of the ingredients. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking ...

How old do you have to be to take clonidine?

talk to your doctor about the risks and benefits of using clonidine if you are 65 years of age or older. Older adults should not usually use clonidine because it is not as safe as other medications that can be used to treat the same condition.

Can you take clonidine if you have dental surgery?

Older adults should not usually use clonidine because it is not as safe as other medications that can be used to treat the same condition. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking clonidine. you should know that clonidine may make you drowsy or dizzy.

How long does clonidine last?

Following intravenous administration, Clonidine displays biphasic disposition with a distribution half-life of about 20 minutes and an elimination half-life ranging from 12 to 16 hours. The half-life increases up to 41 hours in patients with severe impairment of renal function. Clonidine crosses the placental barrier.

How many mg of clonidine hydrochloride is in 0.1 mg?

Clonidine hydrochloride, USP is a centrally acting alpha-agonist hypotensive agent available as tablets for oral administration in three dosage strengths: 0.1 mg, 0.2 mg, and 0.3 mg. The 0.1 mg tablet is equivalent to 0.087 mg of the free base.

Does clonidine increase heart rate?

Clonidine stimulates alpha-adrenoreceptors in the brain stem. This action results in reduced sympathetic outflow from the central nervous system and in decreases in peripheral resistance, renal vascular resistance, heart rate, and blood pressure. Clonidine hydrochloride tablets act relatively rapidly.

Does clonidine slow pulse rate?

Slowing of the pulse rate has been observed in most patients given Clonidine, but the drug does not alter normal hemodynamic response to exercise. Tolerance to the antihypertensive effect may develop in some patients, necessitating a reevaluation of therapy.

How long does it take for clonidine to reach peak levels?

Peak plasma Clonidine levels are attained in approximately 1 to 3 hours. Following intravenous administration, Clonidine displays biphasic disposition with a distribution half-life of about 20 minutes and an elimination half-life ranging from 12 to 16 hours.

Does clonidine cross the blood brain barrier?

Clonidine crosses the placental barrier. It has been shown to cross the blood-brain barrier in rats. Following oral administration about 40% to 60% of the absorbed dose is recovered in the urine as unchanged drug in 24 hours. About 50% of the absorbed dose is metabolized in the liver.

Does clonidine cause headaches?

Sudden cessation of Clonidine treatment has, in some cases, resulted in symptoms such as nervousness, agitation, headache, and tremor accompanied or followed by a rapid rise in blood pressure and elevated catecholamine concentrations in the plasma.

When to take clonidine?

Clonidine is usually taken in the morning and at bedtime. If you take different doses of this medicine at each dosing time, it may be best to take the larger dose at bedtime. Clonidine may be taken with or without food. Do not use two forms of clonidine at the same time.

Is clonidine safe for you?

To make sure clonidine is safe for you, tell your doctor if you have: heart disease or severe coronary artery disease; heart rhythm disorder, slow heartbeats; low blood pressure, or a history of fainting spells; a history of heart attack or stroke; pheochromocytoma (tumor of the adrenal gland); kidney disease; or.

What are the side effects of Clonidine?

Get emergency medical help if you have signs of an allergic reaction to clonidine: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: severe chest pain, shortness of breath, irregular heartbeats; a very slow heart rate; severe headache, pounding in your neck ...

Does clonidine lower blood pressure?

Clonidine lowers blood pressure by decreasing the levels of certain chemicals in your blood. This allows your blood vessels to relax and your heart to beat more slowly and easily. The Catapres brand of clonidine is used to treat hypertension (high blood pressure).

Can you take Clonidine if you are allergic to it?

You should not take this medicine if you are allergic to clonidine. To make sure clonidine is safe for you, tell your doctor if you have: heart disease or severe coronary artery disease; heart rhythm disorder, slow heartbeats; low blood pressure, or a history of fainting spells; a history of heart attack or stroke;

Can clonidine harm a baby?

Older adults may be more sensitive to the effects of this medicine. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while taking clonidine. Clonidine can pass into breast milk and may harm a nursing baby.

Can you give a baby clonidine?

Clonidine can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby. Catapres is not approved for use by anyone younger than 18 years old. Do not give Kapvay to a child younger than 6 years old.

Does Clonidine help with anxiety?

Anxiety: Clonidine for anxiety works by reducing the activity of the sympathetic nervous system. It can be used on its own to treat this health condition.

Can you combine Clonidine with stimulants?

Doctors can combine it with the stimulant drugs used to treat the condition for more efficacy. There are more off-label Clonidine uses for this medication than those that are FDA-approved. It demonstrates the versatility of this medication to an extent.

Is Catapres a clonidine?

Catapres is an effective medication with a wide array of uses. The Clonidine classification of drugs is known as centrally-acting alpha agonists. This is because they activate receptors in the brain known as alpha-adrenergic receptors. It is commonly sold under the brand name Catapres or Kapvay.

Does clonidine help with Tourette's syndrome?

Clonidine for kids with Tourette’s syndrome helps to decrease the severity and intensity of tics. Catapres works by acting on a different chemical system to dopamine by stimulating adrenaline receptors in the brain.

When was Catapres approved?

The development of Catapres was centered around its effect in lowering blood pressure. It was approved for the treatment of high blood pressure in 1974. Catapres drug class belongs to centrally acting alpha-agonist hypotensive agents. Сlonidine HCl can reduce tone in the sympathetic section of the central nervous system.

Does clonidine cause Xerostomia?

Xerostomia is a common side effect of clonidine and is often uncomfortable enough that patients stop using the drug. Counseling patients to chew sugar-free gum and take frequent sips of liquid can help alleviate this discomfort. Drowsiness is common, but this side effect becomes less intense over time.

What is Xerostomia with Clonidine?

Click card to see definition 👆. Tap card to see definition 👆. ANS: A. Xerostomia is a common side effect of clonidine and is often uncomfortable enough that patients stop using the drug. Counseling patients to chew sugar-free gum and take frequent sips of liquid can help alleviate this discomfort. Drowsiness is common, but this side effect ...

Is clonidine hypotensive to posture?

Patients should be counseled to avoid hazardous activities in the first weeks of therapy if they feel this effect. The hypertensive effects of clonidine are not posture dependent, as they are with the peripheral alpha-adrenergic blockers, so orthostatic hypotension is minimal with this drug.

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Medical uses

  • Clonidine tablets (Catapres) are used alone or in combination with other medications to treat high blood pressure. Clonidine extended-release (long-acting) tablets (Kapvay) are used alone or in combination with other medications as part of a treatment program to control symptoms of attention deficit hyperactivity disorder (ADHD; more difficulty foc...
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Administration

  • Clonidine comes as a tablet and an extended-release (long-acting) tablet to take by mouth. The tablet is usually taken two times a day at evenly spaced intervals. The extended-release tablet is usually taken once or twice a day with or without food. Take clonidine at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or phar…
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Treatment

  • Your doctor may start you on a low dose of clonidine and gradually increase your dose, not more than once every week. Clonidine may help to control your condition but will not cure it. Continue to take clonidine even if you feel well. Do not stop taking clonidine without talking to your doctor. If you suddenly stop taking clonidine, it can cause a rapid rise in your blood pressure and sympto…
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Risks

  • Clonidine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
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Prevention

  • Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, t…
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Results

  • Keep all appointments with your doctor. Your blood pressure should be checked regularly to determine your response to clonidine.
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Diagnosis

  • Your doctor may ask you to check your pulse (heart rate) daily and will tell you how rapid it should be. Ask your doctor or pharmacist to teach you how to take your pulse. If your pulse is slower or faster than it should be, call your doctor before taking this medication that day.
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