Treatment FAQ

cardiac sympathetic denervation for treatment of ventricular arrhythmia: where are we now?

by Tyrell Veum Published 2 years ago Updated 2 years ago
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Cardiac sympathetic denervation is now commonly accomplished by a video-assisted thoracoscopic surgical procedure which bisects the stellate ganglion removing the lower half along with a few ganglia below it.Jul 12, 2017

Is cardiac sympathetic denervation effective for ventricular arrhythmia?

In summary, cardiac sympathetic denervation is markedly effective for long QT syndrome and catecholaminergic polymorphic VT. For the remaining ventricular arrhythmia syndromes, early data are encouraging in certain subgroups, but more information is needed.

Which side of the heart for cardiac sympathetic denervation?

In this study, cardiac sympathetic denervation surgery will be performed on both the left and right side, which is supported by some recent evidence, although there have been questions in the past about the effects of right sided denervation. 9

What is left cardiac sympathetic denervation (LCSD)?

Left cardiac sympathetic denervation (LCSD) may reduce the wide gap between life-long ß-blocker medication and ICD implantation. Although LCSD is highly effective in prevention of cardiac events in patients with LQTS and CPVT, it is rarely used.

What is the role of cardiac sympathetic denervation in Chagas disease?

Cardiac sympathetic denervation for intractable ventricular arrhythmias in Chagas disease In patients with chagasic CM presenting with refractory monomorphic VT, early evidence suggests that BCSD reduces appropriate ICD therapy and may represent a valuable treatment option.

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What is used in the treatment of rapid ventricular arrhythmias?

Amiodarone is perhaps the most potent antiarrhythmic in suppressing all types ventricular arrhythmia episodes. IV verapamil can be useful in verapamil sensitive VT.

What medicine is a drug of choice for treatment of ventricular arrhythmia?

Amiodarone (Cordarone, Pacerone, Nexterone) Amiodarone is the drug of choice for the treatment of hemodynamically unstable VT that is refractory to other antiarrhythmic agents.

What is a cardiac sympathectomy?

Procedure: Cardiac Sympathetic Denervation (CSD) Cardiac sympathetic denervation is performed using an endoscopic procedure called VATS (video-assisted thoracoscopic sympathectomy). The surgeon removes the lower half of the stellate ganglia in addition to the thoracic ganglia of T2 - T4 on both the right and left side.

Can VT be cured?

Ventricular Tachycardia (VT) in patients without structural heart disease. Ventricular tachycardia can also occur in patients with structurally normal hearts, unrelated to any history of coronary artery disease. It can occur in both the young and the old, and can be a benign, potentially treatable and curable condition ...

What is the most effective antiarrhythmic drug?

Amiodarone is considered the most potent antiarrhythmic agent. The adverse event profile with amiodarone can be intolerable, with gastrointestinal effects the most common side effect.

What is left cardiac sympathetic denervation?

Left cardiac sympathetic denervation (LCSD) is a surgical antiadrenergic intervention with a strong antiarrhythmic effect, supported by preclinical as well as clinical data.

What is sympathectomy procedure?

Sympathectomy is a type of minimally-invasive procedure (small incisions of 2–3 inches long, done under general anesthesia) which involves cauterizing (cutting and sealing) a portion of the sympathetic nerve chain that runs down the back inside the chest, parallel to the spine.

What sympathetic nerve Innervates the heart?

The heart is innervated by vagal and sympathetic fibers. The right vagus nerve primarily innervates the SA node, whereas the left vagus innervates the AV node; however, there can be significant overlap in the anatomical distribution.

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