Treatment FAQ

after efudex treatment how do i know if i have a skin infection

by Dr. Taurean Botsford Published 2 years ago Updated 2 years ago

Your skin may tend to be dry and flaky for several weeks once you start the healing after Efudex. Find a nice, mild moisturizer that won’t create an excess amount of oil on the skin. Don’t be surprised if you see a pimple or two pop up in the treated area during healing.

Full Answer

Will my skin ever look normal after Efudex treatment?

If you are using Efudex now or gearing up to start treatment, you will soon realize that the area following treatment is nothing like it was when you started. Healing after Efudex can be hard! You may, in fact, wonder if your skin will ever look normal again.

How do I use Efudex topical medicine?

Topical medicine is for use only on the skin. Clean the area where you will apply Efudex. Rinse well and dry the area with a towel and wait ten minutes before applying the medication. Wash your hands before and immediately after applying this medicine, unless it is being used to treat a hand condition.

What are the side effects of Efudex?

Despite what many of us hear from prescribing physicians--it’s can be a real ordeal. From the itching and burning sensation during treatment to the withdrawal-type effects of the healing stage, Efudex brings with it a long list of questions.

What should I do after Efudex treatment?

This area will be sensitive for a while, and the last thing you want is a sunburn on an area you just worked so hard to get healthy. Your skin may tend to be dry and flaky for several weeks once you start the healing after Efudex. Find a nice, mild moisturizer that won’t create an excess amount of oil on the skin.

Can Efudex cause infection?

Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: stomach/abdominal pain, bloody diarrhea, vomiting, signs of infection (such as fever, chills, persistent sore throat), easy bruising/bleeding, mouth sores.

What does Efudix ulceration look like?

When Efudix is applied to the skin, the following usually happens: a redness of the affected area (generally within 3 to 5 days) followed by blistering, peeling, and cracking (within 11 to 14 days) with occasional open sores and some discomfort.

Can Efudix damage your skin?

What are the side effects of Efudix cream? The main side effect is skin irritation (dermatitis). The cream works by directly destroying the sun-damaged skin cells. This will cause intense inflammation, crusting, redness and oozing of the whole area treated.

What happens if you use too much Efudex?

The most frequent adverse reactions to EFUDEX occur locally and are often related to an extension of the pharmacological activity of the drug. These include burning, crusting, allergic contact dermatitis, pruritus, scarring, rash, soreness, and ulceration.

What does skin look like after using Efudix?

After 5 to 10 days of treatment, the sun-damaged parts of treated skin become red and scaly. As treatment is continued, sores and crusts may appear. These raw areas result from the destruction of defective skin cells.

Can you use Efudex too long?

Continue using Efudix for as long as your doctor has told you to. Continue treatment up until the ulceration stage, usually 3 to 4 weeks. The healing process is usually complete 1 to 2 months after the end of treatment.

What does skin look like after fluorouracil treatment?

After five to ten days of treatment, the sun-damaged parts of treated skin become red, scaly and tender. As treatment is continued, sores and crusts may appear. These raw areas result from the destruction of defective skin cells.

Can you have a mild reaction to Efudex?

It is very important to understand that your skin will react during the treatment. Some people have a mild reaction, others have a severe reaction. The reaction involves redness, inflammation, irritation, crusting and peeling.

What should I put on skin after Efudex treatment?

You may apply Aquaphor, Vaseline, or over-the-counter Hydrocortisone ointment to the area treated after applying Efudex.

How do you know when to stop using fluorouracil cream?

If you are using fluorouracil to treat actinic or solar keratoses, you should continue using it until the lesions start to peel off. This usually takes about 2 to 4 weeks. However, the lesions may not be completely healed until 1 or 2 months after you stop using fluorouracil.

Does Efudix cause itching?

As the skin grows accustomed to not receiving the cream, it begins to act out. The burning and itching magnify and, depending on the area being treated, it can become all but impossible to move freely without pain.

Can using Efudex make you tired?

Other than changes to the skin, potential side effects of Efudex include: trouble sleeping. irritability. temporary hair loss.

What is Efudex used for?

Efudex (for the skin) is used to treat scaly overgrowths of skin (actinic or solar keratosis ). Efudex is also used to treat superficial basal cell carcinoma. Efudex may also be used for purposes not listed in this medication guide.

How to get rid of fluorouracil in eyes?

Rinse with water or saline if this medicine gets in your eyes. Do not let Efudex build up in the skin folds around your mouth, nose, or eyes. Use caution when applying the medicine around these areas. Avoid using other medications on the areas you treat with fluorouracil unless your doctor tells you to.

Can you take Efudex while pregnant?

Do not use Efudex if you are pregnant. It could harm the unborn baby or cause birth defects.

Can Efudex cause hives?

Efudex side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using Efudex and call your doctor at once if you have: severe pain or swelling of treated skin; severe itching, burning, or irritation; new or worsening skin sores;

Can you use Efudex on skin?

Apply only enough medicine to cover the affected skin with a thin film. Do not apply Efudex to skin that is irritated, peeling , or infected or on open wounds. Wait until these conditions have fully healed before using this medicine.

How long does it take for a dead skin to fade?

Generally speaking, we all reach our peak at different rates. Somewhere in the most commonly prescribed 2-4 week treatment period, the skin seeps and might begin to bleed in small areas. This is known as the erosion phase and signals the end of the treatment. Redness and irritation ramp up for several days (3-5 days for me), but it does, indeed, begin to fade. In fact, once you are able to gently remove the loose dead skin in the shower, you will notice the redness beginning to slowly dissipate.

What happens when you use chemo cream?

Over the course of a few weeks, you watch your skin turn red, become angry, and dark spots rise to the surface and form scabs. When it’s over, you have more questions.

What is the cream called for skin cancer?

Your dermatologist may find a suspicious spot you thought was just dry skin. She begins a discussion with you and mentions a cream called Efudex - a strange word in and of itself. You find yourself using the cream, a topical chemotherapy, to treat spots on your skin you didn’t know you had.

How long does it take for redness to go away after showering?

Redness and irritation ramp up for several days (3-5 days for me), but it does, indeed, begin to fade. In fact, once you are able to gently remove the loose dead skin in the shower, you will notice the redness beginning to slowly dissipate.

Does Efudex make your skin red?

Since I began using Efudex in 2014, I have noticed that the cream affects users in different ways. Some of us notice irritation and slight redness with the first application while others may not see any visible signs of redness for over a week into treatment. One thing all users seem to have in common is the fact their skin reddens, itches and burns, and can become inflamed as treatment progresses. Once the cream is no longer being regularly applied, the skin begins to tighten as it expects the cream to soften it daily. When this doesn’t happen, users across the board fear their skin will maintain this redness and inflammation.

Does redness fade with time?

The good news is that the redness does, indeed, disappear with time. Resuming your work or school schedule does not have to be put on hold. For me, the relief of having treatment behind me far outweighs any worry I might have over lingering redness. I know it feels like there is no end in sight and the road is weary, but that bit of red skin that wants to stick around is a gradually fading reminder of your strength and determination. Wear it like a badge of honor.

What is Efudex used for?

Efudex, a topical chemotherapy, is commonly prescribed by dermatologists to fight actinic keratoses, and with that prescription comes a plethora of questions. Some of the most frequent questions I have been asked as a regular Efudex user are, “What do you use to ease the pain and itching?” and “How do you cover the redness?”.

How long does it take for a pink skin peel to go away?

That area will remain red and tender for several weeks, and the overall pink tone may be present for a few months.

How to treat efudex?

These are two types of topical creams that doctors usually prescribe on the first and second days of healing after your Efudex treatment has been stopped 1. Mix and apply the two creams on the affected area two to three times daily, but preferably once after waking up and another one in the evening . During this time, expect your skin to crack and bleed and sting, and expect your eyes to swell.

How long does it take for Efudex to heal?

After the period of treatment, which usually lasts two to four weeks, you need another one to two months of healing.

How to treat a stinging scab?

Use an analgesic such as Tylenol to reduce the pain from the fourth to sixth days of healing. Expect a more stinging pain, a bloody broken skin and severe itchiness on the affected part. Apply sunscreen to protect the healing skin when you go out.

When does pinkness stop?

The itchiness is expected to stop and the pinkness reduced by the 28th day. Everything will be back to normal by the 36th day, although some patients might recover completely on the 22nd day.

Can you use cosmetics on basal cell skin cancer?

Local treatments other than surgery for basal and squamous cell skin cancers. Tips. During the healing process, never use any cosmetics or other skin products. If ever you forget an application of the creams, simply resume application as prescribed by your doctor without increasing or doubling the dose.

What is the erosion stage of Efudex?

What is the Efudex erosion stage? Erosion is the end of your Efudex treatment. This is the point at which you and your doctor will together decide to cease application of the chemotherapy cream. Simply put, the cream has done all it can, and it’s time to begin healing.

How long does it take for a dermatologist to tell you enough?

One day at a time. I know. I know. None of that sounds hopeful or positive. Your dermatologist thinks you can handle it, and so do I. Three to four weeks sounds like an eternity, but it passes more quickly when you know what to watch for. Keep in mind, only your doctor can tell you when enough is enough.

When does seeping occur?

Generally speaking, around the third or fourth week (patient instructions vary by case and doctor), seeping can occur. Clear fluid will escape the dry irritated skin through tiny cracks and can make its way to the surface. The seeping is cool. I don’t mean that in the way we have all come to know “cool.”.

Does cream burn your chest?

The cream absorbs more and more quickly as the days go by, and the treated area stiffens, tugs and pulls when you move, and this can cause the burning sensations to temporarily intensify. It’s during erosion that I feel much better sitting as still as possible.

What is the purpose of Efudex?

The purpose of using Efudex, topical chemotherapy, is to bring precancerous cells to the surface and remove them in the form of dead skin. When treatment is done, the actinic keratoses (AKs) your doctor diagnosed will, hopefully, be replaced with new, healthy skin.

How long does it take for a cream to crack?

With every application, your skin grows redder and itches with a steadily increasing intensity. After a couple of weeks, the skin where you are applying the cream is painful, unsightly, and is beginning to crack open.

Using Efudex for actinic keratoses

In 2014, when I was first prescribed Efudex for treatment of recurring actinic keratoses on my chest, I had very few questions because I assumed I was going to be applying a cream not unlike others I already used.

Skincare when using Efudex: Advice from my dermatologist

Before leaving the office with my prescription in hand, my dermatologist provided the following guidance:

Water, it is!

It all seemed very straightforward. Don’t use anything but water. That’s easier said than done when you are used to washing with cleansers, lotioning up, and going about your day. However, once I got used to the treatment phase and found support to help deal with the side effects, rinsing off and patting dry became my new normal.

Healing and avoiding makeup

Three years later, when my dermatologist prescribed Efudex for my face to treat what appeared to be two large precancers, I found out a little more about how long I would have to follow the water-only regimen. Following almost four weeks of applying the cream twice a day, I entered the erosion phase and began healing.

Here comes the concealer

Even though I looked forward to getting back to normal, using my usual products, and wearing makeup again, I had become more than accustomed to going without all of it. The focus was on healing. Makeup was the last thing on my mind by this point. Watching my skin make almost daily dramatic changes for the better, was far more satisfying.

You don't have to face it all alone

I don’t want you to go into treatment blind. Hopefully, you have a dermatologist who covers all the bases for you before you leave the office. If you don’t, reach out to us. You will have questions about products and when it is safe to use them.

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This article represents the opinions, thoughts, and experiences of the author; none of this content has been paid for by any advertiser. The SkinCancer.net team does not recommend or endorse any products or treatments discussed herein. Learn more about how we maintain editorial integrity here.

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